Click here to switch to the map view.

The map label for this gene is hfq [H]

Identifier: 150396314

GI number: 150396314

Start: 1165507

End: 1165749

Strand: Direct

Name: hfq [H]

Synonym: Smed_1095

Alternate gene names: 150396314

Gene position: 1165507-1165749 (Clockwise)

Preceding gene: 150396313

Following gene: 150396315

Centisome position: 30.82

GC content: 51.44

Gene sequence:

>243_bases
ATGGCGGAACGTTCTCAAAACTTGCAGGATCTATTTCTCAACACGGTCCGCAAGCAAAAGATTTCTTTGACCATTTTCCT
CATCAATGGCGTGAAGCTGACGGGTGTCGTAACATCGTTTGACAATTTCTGTGTACTGCTTCGCCGCGACGGCCATTCTC
AGCTCGTCTACAAGCACGCCATCTCGACGATCATGCCGGGCCAGCCGCTGCAGATGTTCGAGAATGAGGAAGCTGCCTCC
TGA

Upstream 100 bases:

>100_bases
CCAAACCTCTCGGAGGTGTCGGGGTTCGTTCGTGGCACCTTAAAAAATTGACAAAATGCACCGGTGAAAGAACGCCGGCA
AATAAGAAAGAAGCGGCGCG

Downstream 100 bases:

>100_bases
CGGGACGTGAGGAACATTACCAAGCGTGATTCAAAATCGTCGTCGATTATCCCGGAGCTTGAGCGGCTCCGTGATGACTC
GCGTGCCGTGGTCGTCGTCC

Product: RNA-binding protein Hfq

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 80; Mature: 79

Protein sequence:

>80_residues
MAERSQNLQDLFLNTVRKQKISLTIFLINGVKLTGVVTSFDNFCVLLRRDGHSQLVYKHAISTIMPGQPLQMFENEEAAS

Sequences:

>Translated_80_residues
MAERSQNLQDLFLNTVRKQKISLTIFLINGVKLTGVVTSFDNFCVLLRRDGHSQLVYKHAISTIMPGQPLQMFENEEAAS
>Mature_79_residues
AERSQNLQDLFLNTVRKQKISLTIFLINGVKLTGVVTSFDNFCVLLRRDGHSQLVYKHAISTIMPGQPLQMFENEEAAS

Specific function: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs [H]

COG id: COG1923

COG function: function code R; Uncharacterized host factor I protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hfq family [H]

Homologues:

Organism=Escherichia coli, GI1790614, Length=72, Percent_Identity=47.2222222222222, Blast_Score=81, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005001
- InterPro:   IPR010920
- InterPro:   IPR001163 [H]

Pfam domain/function: PF01423 LSM [H]

EC number: NA

Molecular weight: Translated: 9054; Mature: 8922

Theoretical pI: Translated: 8.53; Mature: 8.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAERSQNLQDLFLNTVRKQKISLTIFLINGVKLTGVVTSFDNFCVLLRRDGHSQLVYKHA
CCCCCCCHHHHHHHHHCCCEEEEEEEEECCEEEEEEEECCCCEEEEEEECCCCHHHHHHH
ISTIMPGQPLQMFENEEAAS
HHHCCCCCCHHHCCCCCCCC
>Mature Secondary Structure 
AERSQNLQDLFLNTVRKQKISLTIFLINGVKLTGVVTSFDNFCVLLRRDGHSQLVYKHA
CCCCCCHHHHHHHHHCCCEEEEEEEEECCEEEEEEEECCCCEEEEEEECCCCHHHHHHH
ISTIMPGQPLQMFENEEAAS
HHHCCCCCCHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA