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The map label for this gene is degQ [H]

Identifier: 150396235

GI number: 150396235

Start: 1084606

End: 1086003

Strand: Direct

Name: degQ [H]

Synonym: Smed_1014

Alternate gene names: 150396235

Gene position: 1084606-1086003 (Clockwise)

Preceding gene: 150396232

Following gene: 150396236

Centisome position: 28.68

GC content: 62.3

Gene sequence:

>1398_bases
ATGATCTTTGGCCACCGAGCCGCCGCGGCTATCGTCCTCGCAATTGCCATTTCGACGCCTGCGATGGCTCAGGATACCAG
GACTGTGCCGCAGTCGCGGGCGGAGATGCAACTCTCTTTCGCGCCGCTCGTCAAACAGACGGCGAATGCGGTCGTGAACG
TCTATGCCGAGCGCGCGGTGGAACGGCGGTCGATCTTTGCCGGGGACCCTTTCTTCGAGGAGTTTTTCGGTCAGCGGATG
CCCAATCGCACCGAAAAGCAGTCATCGCTCGGATCAGGCGTGATCGTCGGCCGCAACGGCCTGGTCGTCACCAACAACCA
TGTCATCGATGGTGCCGACGATATCAAGGTGGCACTGGCCGACGGGCGGGAGTTCCCTTGCAAGCTTATATTGAAGGACG
ATCGCCTGGACCTCGCGGTCATGAAAATCCAGTCGGACGGCCCGTTCGACATCATCCCGATCGGCGATTCCGACGCGGTG
GAAGTCGGGGACCTTGTGCTGGCGATGGGTAATCCTTTCGGTGTCGGGCAGACGGTCACGAGCGGCATCGTGTCGGCACT
CGCCCGTAACCAGATTTCCAACGGGGATTTCGGTTTTTTCATCCAGACGGATGCAGCCATCAATCCCGGCAATTCCGGCG
GGGGTCTGATCGACATGAAGGGCGAGTTGATCGGAATCAACACCGCGATTTTCTCAAGAGGCGGCGGTTCCAACGGTGTC
GGCTTTGCGATCCCTGCCAATCTGGTCAAGGTTTTCGTGGCCTCCGCTGAAGGAGGCAATGGCTCATTCATTCGGCCCTT
CGTCGGAGCGACCTTCGAACCGGTGACGTCCGACGTGGCCGAGGCGCTTGGACTTGAACGGGCGCGTGGGGCGCTGGTGA
CGGCGGTTGTCGCGGGCGGTCCGGCCGAGAGCGCCGGCATGCGCCCCGGCCAGGTGGTCACCGCCGTCAACGATATACCG
GTCGAACACCCCGATGCGCTCGGCTACCGCCTGACGACGGTCGGGATCGGGCATGAGGCGCGCGTGACGGTTTCGGAGAA
CGGCGATTTGCGCGAAATCACCCTCCGGCTGGAGCGGGCGCCGGAAACTCAGCCGCGTGACGAACGGCTGATCGAGGGTC
GCAATCCCTTCGCCGGCGCCGTGGTGGCAAATCTCTCACCCCGGCTTGCCGAGGAGTTGCGCATGCCGACGTCGCTGCAG
GGCGTGGTGGTCACCGAGATCAATCGCGGCTCGCCGGCCGCTCGCATCGGCCTCGAACCGAAAGACATTGTTCGTTCTGT
CAACGGCACCGCAATCGAGAGTTCGAAGACACTGGAAAGCGTCGTCGCCGAGGATGCTTCCTTCTGGCGTGTCGAGATCG
AACGCAACGGCCAGATCATCCGTCAGTTCTTCCGATGA

Upstream 100 bases:

>100_bases
GGCTTTGCAATCAGGAAACGCTGAATTGTCGGGCGGCAGGTTTGCCTTTTTTCGTACGAAATCCTATCTCACCTAGCAGC
AATGAAAGGGAGACTGCTTC

Downstream 100 bases:

>100_bases
GCGACCTCTTCGCCCCCCATGAACCTCCTGAGATGGCCTCGGCAAGGCCACTTGCGGACCGGCTGCGGCCGCGTACGCTG
GGAGAGGTGACCGGCCAGGA

Product: protease Do

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 465; Mature: 465

Protein sequence:

>465_residues
MIFGHRAAAAIVLAIAISTPAMAQDTRTVPQSRAEMQLSFAPLVKQTANAVVNVYAERAVERRSIFAGDPFFEEFFGQRM
PNRTEKQSSLGSGVIVGRNGLVVTNNHVIDGADDIKVALADGREFPCKLILKDDRLDLAVMKIQSDGPFDIIPIGDSDAV
EVGDLVLAMGNPFGVGQTVTSGIVSALARNQISNGDFGFFIQTDAAINPGNSGGGLIDMKGELIGINTAIFSRGGGSNGV
GFAIPANLVKVFVASAEGGNGSFIRPFVGATFEPVTSDVAEALGLERARGALVTAVVAGGPAESAGMRPGQVVTAVNDIP
VEHPDALGYRLTTVGIGHEARVTVSENGDLREITLRLERAPETQPRDERLIEGRNPFAGAVVANLSPRLAEELRMPTSLQ
GVVVTEINRGSPAARIGLEPKDIVRSVNGTAIESSKTLESVVAEDASFWRVEIERNGQIIRQFFR

Sequences:

>Translated_465_residues
MIFGHRAAAAIVLAIAISTPAMAQDTRTVPQSRAEMQLSFAPLVKQTANAVVNVYAERAVERRSIFAGDPFFEEFFGQRM
PNRTEKQSSLGSGVIVGRNGLVVTNNHVIDGADDIKVALADGREFPCKLILKDDRLDLAVMKIQSDGPFDIIPIGDSDAV
EVGDLVLAMGNPFGVGQTVTSGIVSALARNQISNGDFGFFIQTDAAINPGNSGGGLIDMKGELIGINTAIFSRGGGSNGV
GFAIPANLVKVFVASAEGGNGSFIRPFVGATFEPVTSDVAEALGLERARGALVTAVVAGGPAESAGMRPGQVVTAVNDIP
VEHPDALGYRLTTVGIGHEARVTVSENGDLREITLRLERAPETQPRDERLIEGRNPFAGAVVANLSPRLAEELRMPTSLQ
GVVVTEINRGSPAARIGLEPKDIVRSVNGTAIESSKTLESVVAEDASFWRVEIERNGQIIRQFFR
>Mature_465_residues
MIFGHRAAAAIVLAIAISTPAMAQDTRTVPQSRAEMQLSFAPLVKQTANAVVNVYAERAVERRSIFAGDPFFEEFFGQRM
PNRTEKQSSLGSGVIVGRNGLVVTNNHVIDGADDIKVALADGREFPCKLILKDDRLDLAVMKIQSDGPFDIIPIGDSDAV
EVGDLVLAMGNPFGVGQTVTSGIVSALARNQISNGDFGFFIQTDAAINPGNSGGGLIDMKGELIGINTAIFSRGGGSNGV
GFAIPANLVKVFVASAEGGNGSFIRPFVGATFEPVTSDVAEALGLERARGALVTAVVAGGPAESAGMRPGQVVTAVNDIP
VEHPDALGYRLTTVGIGHEARVTVSENGDLREITLRLERAPETQPRDERLIEGRNPFAGAVVANLSPRLAEELRMPTSLQ
GVVVTEINRGSPAARIGLEPKDIVRSVNGTAIESSKTLESVVAEDASFWRVEIERNGQIIRQFFR

Specific function: Protease with a shared specificity with degP [H]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=259, Percent_Identity=33.976833976834, Blast_Score=137, Evalue=3e-32,
Organism=Homo sapiens, GI7019477, Length=305, Percent_Identity=33.4426229508197, Blast_Score=135, Evalue=1e-31,
Organism=Homo sapiens, GI24308541, Length=244, Percent_Identity=32.7868852459016, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI22129776, Length=299, Percent_Identity=29.7658862876254, Blast_Score=116, Evalue=4e-26,
Organism=Escherichia coli, GI1789629, Length=461, Percent_Identity=34.9240780911063, Blast_Score=249, Evalue=3e-67,
Organism=Escherichia coli, GI1786356, Length=469, Percent_Identity=34.7547974413646, Blast_Score=247, Evalue=1e-66,
Organism=Escherichia coli, GI1789630, Length=298, Percent_Identity=37.9194630872483, Blast_Score=163, Evalue=2e-41,
Organism=Drosophila melanogaster, GI24646839, Length=290, Percent_Identity=33.1034482758621, Blast_Score=139, Evalue=5e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 49195; Mature: 49195

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFGHRAAAAIVLAIAISTPAMAQDTRTVPQSRAEMQLSFAPLVKQTANAVVNVYAERAV
CCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHEEEHHHHHHHHHHHHHHHHHHHHHH
ERRSIFAGDPFFEEFFGQRMPNRTEKQSSLGSGVIVGRNGLVVTNNHVIDGADDIKVALA
HHHHCCCCCCHHHHHHHHHCCCCHHHHHCCCCCEEEECCCEEEECCEEECCCCCEEEEEE
DGREFPCKLILKDDRLDLAVMKIQSDGPFDIIPIGDSDAVEVGDLVLAMGNPFGVGQTVT
CCCCCCEEEEEECCCCEEEEEEEECCCCEEEEECCCCCCEECCEEEEECCCCCCCCHHHH
SGIVSALARNQISNGDFGFFIQTDAAINPGNSGGGLIDMKGELIGINTAIFSRGGGSNGV
HHHHHHHHHHCCCCCCEEEEEEECCEECCCCCCCCEEEECCCEEEEEHEEEECCCCCCCC
GFAIPANLVKVFVASAEGGNGSFIRPFVGATFEPVTSDVAEALGLERARGALVTAVVAGG
EEECHHHHEEEEEEECCCCCCCEECHHHCCCCCHHHHHHHHHHCHHHHCCEEEEEEEECC
PAESAGMRPGQVVTAVNDIPVEHPDALGYRLTTVGIGHEARVTVSENGDLREITLRLERA
CCHHCCCCCCEEEEEECCCCCCCCCCCCEEEEEEECCCCEEEEECCCCCEEEEEEEEECC
PETQPRDERLIEGRNPFAGAVVANLSPRLAEELRMPTSLQGVVVTEINRGSPAARIGLEP
CCCCCCHHHHHCCCCCCCCEEEECCCHHHHHHHCCCCCCCCEEEEEECCCCCCEEECCCH
KDIVRSVNGTAIESSKTLESVVAEDASFWRVEIERNGQIIRQFFR
HHHHHHCCCCEECCHHHHHHHHHCCCCEEEEEEECCCHHHHHHHC
>Mature Secondary Structure
MIFGHRAAAAIVLAIAISTPAMAQDTRTVPQSRAEMQLSFAPLVKQTANAVVNVYAERAV
CCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHEEEHHHHHHHHHHHHHHHHHHHHHH
ERRSIFAGDPFFEEFFGQRMPNRTEKQSSLGSGVIVGRNGLVVTNNHVIDGADDIKVALA
HHHHCCCCCCHHHHHHHHHCCCCHHHHHCCCCCEEEECCCEEEECCEEECCCCCEEEEEE
DGREFPCKLILKDDRLDLAVMKIQSDGPFDIIPIGDSDAVEVGDLVLAMGNPFGVGQTVT
CCCCCCEEEEEECCCCEEEEEEEECCCCEEEEECCCCCCEECCEEEEECCCCCCCCHHHH
SGIVSALARNQISNGDFGFFIQTDAAINPGNSGGGLIDMKGELIGINTAIFSRGGGSNGV
HHHHHHHHHHCCCCCCEEEEEEECCEECCCCCCCCEEEECCCEEEEEHEEEECCCCCCCC
GFAIPANLVKVFVASAEGGNGSFIRPFVGATFEPVTSDVAEALGLERARGALVTAVVAGG
EEECHHHHEEEEEEECCCCCCCEECHHHCCCCCHHHHHHHHHHCHHHHCCEEEEEEEECC
PAESAGMRPGQVVTAVNDIPVEHPDALGYRLTTVGIGHEARVTVSENGDLREITLRLERA
CCHHCCCCCCEEEEEECCCCCCCCCCCCEEEEEEECCCCEEEEECCCCCEEEEEEEEECC
PETQPRDERLIEGRNPFAGAVVANLSPRLAEELRMPTSLQGVVVTEINRGSPAARIGLEP
CCCCCCHHHHHCCCCCCCCEEEECCCHHHHHHHCCCCCCCCEEEEEECCCCCCEEECCCH
KDIVRSVNGTAIESSKTLESVVAEDASFWRVEIERNGQIIRQFFR
HHHHHHCCCCEECCHHHHHHHHHCCCCEEEEEEECCCHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8576051; 9278503 [H]