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The map label for this gene is aroC [H]

Identifier: 150395739

GI number: 150395739

Start: 558536

End: 559633

Strand: Direct

Name: aroC [H]

Synonym: Smed_0515

Alternate gene names: 150395739

Gene position: 558536-559633 (Clockwise)

Preceding gene: 150395737

Following gene: 150395740

Centisome position: 14.77

GC content: 62.93

Gene sequence:

>1098_bases
ATGTCGCACAATACATTCGGTCATCTTTTCCGCGTAACGACCTGGGGGGAAAGCCACGGTCCTGCACTTGGCTGTGTCGT
TGACGGGTGCCCGCCCGGACTTCGCTTCACGCTCGCGGACATTCAAACCTGGCTTGACAAGCGCAAGCCGGGGCAGTCCC
GCTTCGTCACTCAGCGTCGCGAGGACGATCTTGTAAAGGTCCTTTCCGGGGTGATGCTCGACGACGACGGTGAGACGATG
ATTTCCACCGGGACGCCGATTTCGATGTTGATCGAAAACACCGACCAACGGTCCAAGGATTACTCGGAGATCGCCAAGCG
CTATCGCCCGGGCCATGCGGATTATACATATGACGTGAAATACGGCATCCGCGACTATCGCGGCGGCGGCCGCTCCTCGG
CCCGTGAGACGGCTGCACGCGTGGCTGCCGGTGCGATCGCACGCCAGGTCGTCCCCGGTCTCGTCGTGCGCGGCGCGCTC
GTCCAGATCGGCAAGCACAGAATCGACCGCGCCAACTGGGACTGGGCGGAAGTCGGCAAAAACCCGTTCTTTTCTCCCGA
CCCGGCCGTCGTTCCTGTCTGGGAGGAATATCTCGACGGCATCCGCAAAGCCGGCTCGTCGATCGGCGCAATCGTCGAGG
TGATTGCCGAAGGCGTTCCGGCCGGTATAGGCGCACCGATCTACGGCAAGCTCGATCAGGACATCGCCGCCAACCTGATG
TCGATCAATGCCGTAAAGGGCGTGGAGATCGGTAATGGCTTCGCGGCCGCCGAGATCAGCGGCGAAGACAATGCCGACGA
GATGCGTGTCGGGGCAGGGGGCGACGCGGTTTTCCTTTCCAACAATGCCGGCGGCATTCTGGGCGGCATCTCGACCGGGC
AGCCGGTGGTTGCGCGCTTCGCCATCAAGCCGACCTCTTCCATTCTGAGCGAGCGCCGTTCGATCGATAGCGACGGCAAG
GAGGTCGACGTGCGCACCAAGGGTCGCCACGACCCCTGCGTCGGCATCCGGGCCGTACCGATCGGGGAGGCGATGCTTGC
CTGCGCAATCGCCGACCATTACCTGCGTGATCGCGGCCAGACAGGCCGGCTGAAGTAA

Upstream 100 bases:

>100_bases
CGTTGCCACGGAGCGGACCAGCTGCGGCTCCGGGAATTGGAATTGACGCGAAGGTTCGGGCCGGTCCGCCATCTTCGCGA
TCCGGAGTTCGGTAGCCGCC

Downstream 100 bases:

>100_bases
CAAGGCAGTGCAATTGCGGTGAAACAACACGTCGCGGAGATAAAAATGTCCTACGACCAAAAGCGCGTCGTCGAAGCCAT
TCGCGCATTTGAAGCGGGAG

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase [H]

Number of amino acids: Translated: 365; Mature: 364

Protein sequence:

>365_residues
MSHNTFGHLFRVTTWGESHGPALGCVVDGCPPGLRFTLADIQTWLDKRKPGQSRFVTQRREDDLVKVLSGVMLDDDGETM
ISTGTPISMLIENTDQRSKDYSEIAKRYRPGHADYTYDVKYGIRDYRGGGRSSARETAARVAAGAIARQVVPGLVVRGAL
VQIGKHRIDRANWDWAEVGKNPFFSPDPAVVPVWEEYLDGIRKAGSSIGAIVEVIAEGVPAGIGAPIYGKLDQDIAANLM
SINAVKGVEIGNGFAAAEISGEDNADEMRVGAGGDAVFLSNNAGGILGGISTGQPVVARFAIKPTSSILSERRSIDSDGK
EVDVRTKGRHDPCVGIRAVPIGEAMLACAIADHYLRDRGQTGRLK

Sequences:

>Translated_365_residues
MSHNTFGHLFRVTTWGESHGPALGCVVDGCPPGLRFTLADIQTWLDKRKPGQSRFVTQRREDDLVKVLSGVMLDDDGETM
ISTGTPISMLIENTDQRSKDYSEIAKRYRPGHADYTYDVKYGIRDYRGGGRSSARETAARVAAGAIARQVVPGLVVRGAL
VQIGKHRIDRANWDWAEVGKNPFFSPDPAVVPVWEEYLDGIRKAGSSIGAIVEVIAEGVPAGIGAPIYGKLDQDIAANLM
SINAVKGVEIGNGFAAAEISGEDNADEMRVGAGGDAVFLSNNAGGILGGISTGQPVVARFAIKPTSSILSERRSIDSDGK
EVDVRTKGRHDPCVGIRAVPIGEAMLACAIADHYLRDRGQTGRLK
>Mature_364_residues
SHNTFGHLFRVTTWGESHGPALGCVVDGCPPGLRFTLADIQTWLDKRKPGQSRFVTQRREDDLVKVLSGVMLDDDGETMI
STGTPISMLIENTDQRSKDYSEIAKRYRPGHADYTYDVKYGIRDYRGGGRSSARETAARVAAGAIARQVVPGLVVRGALV
QIGKHRIDRANWDWAEVGKNPFFSPDPAVVPVWEEYLDGIRKAGSSIGAIVEVIAEGVPAGIGAPIYGKLDQDIAANLMS
INAVKGVEIGNGFAAAEISGEDNADEMRVGAGGDAVFLSNNAGGILGGISTGQPVVARFAIKPTSSILSERRSIDSDGKE
VDVRTKGRHDPCVGIRAVPIGEAMLACAIADHYLRDRGQTGRLK

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788669, Length=368, Percent_Identity=57.8804347826087, Blast_Score=391, Evalue=1e-110,
Organism=Saccharomyces cerevisiae, GI6321290, Length=368, Percent_Identity=40.2173913043478, Blast_Score=263, Evalue=2e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000453
- InterPro:   IPR020541 [H]

Pfam domain/function: PF01264 Chorismate_synt [H]

EC number: =4.2.3.5 [H]

Molecular weight: Translated: 39100; Mature: 38968

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1 ; PS00788 CHORISMATE_SYNTHASE_2 ; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHNTFGHLFRVTTWGESHGPALGCVVDGCPPGLRFTLADIQTWLDKRKPGQSRFVTQRR
CCCCCCEEEEEEEECCCCCCCEEEEEECCCCCCCEEEHHHHHHHHHHCCCCCHHHHHHHH
EDDLVKVLSGVMLDDDGETMISTGTPISMLIENTDQRSKDYSEIAKRYRPGHADYTYDVK
HHHHHHHHHCCEECCCCCEEEECCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCEEEEEE
YGIRDYRGGGRSSARETAARVAAGAIARQVVPGLVVRGALVQIGKHRIDRANWDWAEVGK
ECCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCC
NPFFSPDPAVVPVWEEYLDGIRKAGSSIGAIVEVIAEGVPAGIGAPIYGKLDQDIAANLM
CCCCCCCCCEECCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHH
SINAVKGVEIGNGFAAAEISGEDNADEMRVGAGGDAVFLSNNAGGILGGISTGQPVVARF
HHHCCCCEEECCCEEEEEECCCCCCCCEEECCCCCEEEEECCCCCEEECCCCCCCEEEEE
AIKPTSSILSERRSIDSDGKEVDVRTKGRHDPCVGIRAVPIGEAMLACAIADHYLRDRGQ
EECCHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCEEECCCHHHHHHHHHHHHHHHCCCC
TGRLK
CCCCC
>Mature Secondary Structure 
SHNTFGHLFRVTTWGESHGPALGCVVDGCPPGLRFTLADIQTWLDKRKPGQSRFVTQRR
CCCCCEEEEEEEECCCCCCCEEEEEECCCCCCCEEEHHHHHHHHHHCCCCCHHHHHHHH
EDDLVKVLSGVMLDDDGETMISTGTPISMLIENTDQRSKDYSEIAKRYRPGHADYTYDVK
HHHHHHHHHCCEECCCCCEEEECCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCEEEEEE
YGIRDYRGGGRSSARETAARVAAGAIARQVVPGLVVRGALVQIGKHRIDRANWDWAEVGK
ECCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCC
NPFFSPDPAVVPVWEEYLDGIRKAGSSIGAIVEVIAEGVPAGIGAPIYGKLDQDIAANLM
CCCCCCCCCEECCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHH
SINAVKGVEIGNGFAAAEISGEDNADEMRVGAGGDAVFLSNNAGGILGGISTGQPVVARF
HHHCCCCEEECCCEEEEEECCCCCCCCEEECCCCCEEEEECCCCCEEECCCCCCCEEEEE
AIKPTSSILSERRSIDSDGKEVDVRTKGRHDPCVGIRAVPIGEAMLACAIADHYLRDRGQ
EECCHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCEEECCCHHHHHHHHHHHHHHHCCCC
TGRLK
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]