Click here to switch to the map view.

The map label for this gene is tldD [H]

Identifier: 150395729

GI number: 150395729

Start: 548041

End: 549456

Strand: Direct

Name: tldD [H]

Synonym: Smed_0505

Alternate gene names: 150395729

Gene position: 548041-549456 (Clockwise)

Preceding gene: 150395728

Following gene: 150395731

Centisome position: 14.49

GC content: 64.41

Gene sequence:

>1416_bases
ATGGATACCAATCTGATCAGCCTCTTCGATGCGGACGAGGCGACGGTCCGCAAGGTTCTCTCCGACACGCTTGCCGGCGC
CGATGACGGCGAACTCTTCCTCGAACATGCGCAGGCGGAGGTGCTCTCCTTCGACAATGGCCGCCTGAAGGGCGGCAGTT
TCAACACCGACCAGGGCTTCGGCCTGCGCGCCGTCGCCGGCGAGGCTGTCGGCTACGCGCATGCCGGCGAGTTGTCGCTC
GCTGCCTTGAAGAGGGCTGCGGACGCGGTGGAGCAGGTGACGCGTGGCTATTCCGGCTCCTATTCGGCAGCGCCGCAGCG
CACCAACAAGAAGCTTTACGGAGACGGAAATCCGATCGGCGAGCCAAGTTTCGAGACCAAGGTGAAGCTGCTCCAGGAGA
TCGATGCCTATCTGCGCGCCAAGGAGGCCAAGGTCAGGCAGGTAACCGCGACGGTCGCTGCGAGCTGGCAGGTCGTGGAT
ATTCTGAGAGCCGATGGACACCGCGTCCACGACGTGCGGCCGATGACGCGGATCAACATCTCCGTCGTGGTCGGCGAGGG
CGACCGGCAGGAAAGCGGATCCTTCGGCATCGGCGGGCGGCGCGGCTTCGGTGAGTTCATCACCGAGGACAGCTGGAAAA
GCGGAGCCGACGAGGCACTGCGGCAGGCGCTTGTCAATCTGGAGGCGATCGACGCGCCGGCGGGCACCATGGACATCGTA
CTTGCCTCCGGCTGGCCCGGCGTCATGCTTCATGAAGCGGTCGGACATGGGCTGGAGGGCGATTTCAACCGCAAGAAAAC
CTCGGCCTTTGCGGGGCTCCTGGGAGAACAGGTTGCTGCCAAAGGCGTTACCGTCGTCGACGACGGTACAATCGAAGCGC
GCCGCGGCTCCATCTCGATCGACGACGAGGGCACACCCTCCGGCTACAACGTCCTGATCGAGGACGGCAAGCTCGTCGGC
TATATGCAGGACCGGCAGAATGCCCGCCTCATGGGCATGGAGCCGACCGGCAACGGCCGCCGCCAGGGCTACGCCCATGT
GCCGATGCCGCGCATGACCAACACCTATATGCTTGCCGGGGACCGCACGCCCGATGAAATCATCTCATCGGTGAAGAAGG
GCATCTATGCCGTCTCATTTGGCGGCGGGCAGGTCGACATCACCTCCGGCAAATTCGTCTTCGGCTGCACCGAGGCCTAC
CTGATCGAGAACGGCAAGGTCGGAGCGCCGGTCAAGGGTGCGATGCTGATCGGCAACGGACCGGATGCGATGAAGCGCGT
GACGATGGTCGGGAACGACACGAAGCTCGACACCGGCATCGGCAATTGCGGAAAGGCCGGCCAGTGGGTCCCGGTTGGCG
TCGGCCAGCCGCACCTGCGGATGGATCAGATCACCGTCGGCGGCACGCAGGCGTGA

Upstream 100 bases:

>100_bases
GATTTCCGGTGGTGTGTTTTTTCTTGGCTTGTCGGCCGGCTCTCCCTAAATGGAGCCAATACGTTTCACGACCCAATCCT
TCACGGCAGGGAGCAGAACC

Downstream 100 bases:

>100_bases
TAAGGCTTACCTCTGTGCTTCGCCACAGAGTGAGGCGTTAGCCCTCGTCGGGAAGCAGGACGCAGTCATAGGACCGCTTC
TTCAGGACGTCGCAGGCGAT

Product: peptidase U62 modulator of DNA gyrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 471; Mature: 471

Protein sequence:

>471_residues
MDTNLISLFDADEATVRKVLSDTLAGADDGELFLEHAQAEVLSFDNGRLKGGSFNTDQGFGLRAVAGEAVGYAHAGELSL
AALKRAADAVEQVTRGYSGSYSAAPQRTNKKLYGDGNPIGEPSFETKVKLLQEIDAYLRAKEAKVRQVTATVAASWQVVD
ILRADGHRVHDVRPMTRINISVVVGEGDRQESGSFGIGGRRGFGEFITEDSWKSGADEALRQALVNLEAIDAPAGTMDIV
LASGWPGVMLHEAVGHGLEGDFNRKKTSAFAGLLGEQVAAKGVTVVDDGTIEARRGSISIDDEGTPSGYNVLIEDGKLVG
YMQDRQNARLMGMEPTGNGRRQGYAHVPMPRMTNTYMLAGDRTPDEIISSVKKGIYAVSFGGGQVDITSGKFVFGCTEAY
LIENGKVGAPVKGAMLIGNGPDAMKRVTMVGNDTKLDTGIGNCGKAGQWVPVGVGQPHLRMDQITVGGTQA

Sequences:

>Translated_471_residues
MDTNLISLFDADEATVRKVLSDTLAGADDGELFLEHAQAEVLSFDNGRLKGGSFNTDQGFGLRAVAGEAVGYAHAGELSL
AALKRAADAVEQVTRGYSGSYSAAPQRTNKKLYGDGNPIGEPSFETKVKLLQEIDAYLRAKEAKVRQVTATVAASWQVVD
ILRADGHRVHDVRPMTRINISVVVGEGDRQESGSFGIGGRRGFGEFITEDSWKSGADEALRQALVNLEAIDAPAGTMDIV
LASGWPGVMLHEAVGHGLEGDFNRKKTSAFAGLLGEQVAAKGVTVVDDGTIEARRGSISIDDEGTPSGYNVLIEDGKLVG
YMQDRQNARLMGMEPTGNGRRQGYAHVPMPRMTNTYMLAGDRTPDEIISSVKKGIYAVSFGGGQVDITSGKFVFGCTEAY
LIENGKVGAPVKGAMLIGNGPDAMKRVTMVGNDTKLDTGIGNCGKAGQWVPVGVGQPHLRMDQITVGGTQA
>Mature_471_residues
MDTNLISLFDADEATVRKVLSDTLAGADDGELFLEHAQAEVLSFDNGRLKGGSFNTDQGFGLRAVAGEAVGYAHAGELSL
AALKRAADAVEQVTRGYSGSYSAAPQRTNKKLYGDGNPIGEPSFETKVKLLQEIDAYLRAKEAKVRQVTATVAASWQVVD
ILRADGHRVHDVRPMTRINISVVVGEGDRQESGSFGIGGRRGFGEFITEDSWKSGADEALRQALVNLEAIDAPAGTMDIV
LASGWPGVMLHEAVGHGLEGDFNRKKTSAFAGLLGEQVAAKGVTVVDDGTIEARRGSISIDDEGTPSGYNVLIEDGKLVG
YMQDRQNARLMGMEPTGNGRRQGYAHVPMPRMTNTYMLAGDRTPDEIISSVKKGIYAVSFGGGQVDITSGKFVFGCTEAY
LIENGKVGAPVKGAMLIGNGPDAMKRVTMVGNDTKLDTGIGNCGKAGQWVPVGVGQPHLRMDQITVGGTQA

Specific function: Suppresses The Inhibitory Activity Of The Carbon Storage Regulator (Csra). [C]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=450, Percent_Identity=53.7777777777778, Blast_Score=466, Evalue=1e-132,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 49897; Mature: 49897

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTNLISLFDADEATVRKVLSDTLAGADDGELFLEHAQAEVLSFDNGRLKGGSFNTDQGF
CCCCEEEEECCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHEEECCCCEECCCCCCCCCCC
GLRAVAGEAVGYAHAGELSLAALKRAADAVEQVTRGYSGSYSAAPQRTNKKLYGDGNPIG
CEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
EPSFETKVKLLQEIDAYLRAKEAKVRQVTATVAASWQVVDILRADGHRVHDVRPMTRINI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCEEECCCCEEEEEE
SVVVGEGDRQESGSFGIGGRRGFGEFITEDSWKSGADEALRQALVNLEAIDAPAGTMDIV
EEEECCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHEECCCCCCEEEE
LASGWPGVMLHEAVGHGLEGDFNRKKTSAFAGLLGEQVAAKGVTVVDDGTIEARRGSISI
EECCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCEEECCCEEEE
DDEGTPSGYNVLIEDGKLVGYMQDRQNARLMGMEPTGNGRRQGYAHVPMPRMTNTYMLAG
CCCCCCCCCEEEEECCEEEEEEECCCCCEEEEECCCCCCCCCCEEECCCCCCCCEEEEEC
DRTPDEIISSVKKGIYAVSFGGGQVDITSGKFVFGCTEAYLIENGKVGAPVKGAMLIGNG
CCCHHHHHHHHHCCEEEEEECCCEEEEECCCEEEECCEEEEEECCCCCCCCCCEEEECCC
PDAMKRVTMVGNDTKLDTGIGNCGKAGQWVPVGVGQPHLRMDQITVGGTQA
HHHHHEEEEECCCCEECCCCCCCCCCCCEEEECCCCCCEEEEEEECCCCCC
>Mature Secondary Structure
MDTNLISLFDADEATVRKVLSDTLAGADDGELFLEHAQAEVLSFDNGRLKGGSFNTDQGF
CCCCEEEEECCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHEEECCCCEECCCCCCCCCCC
GLRAVAGEAVGYAHAGELSLAALKRAADAVEQVTRGYSGSYSAAPQRTNKKLYGDGNPIG
CEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
EPSFETKVKLLQEIDAYLRAKEAKVRQVTATVAASWQVVDILRADGHRVHDVRPMTRINI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCEEECCCCEEEEEE
SVVVGEGDRQESGSFGIGGRRGFGEFITEDSWKSGADEALRQALVNLEAIDAPAGTMDIV
EEEECCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHEECCCCCCEEEE
LASGWPGVMLHEAVGHGLEGDFNRKKTSAFAGLLGEQVAAKGVTVVDDGTIEARRGSISI
EECCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCEEECCCEEEE
DDEGTPSGYNVLIEDGKLVGYMQDRQNARLMGMEPTGNGRRQGYAHVPMPRMTNTYMLAG
CCCCCCCCCEEEEECCEEEEEEECCCCCEEEEECCCCCCCCCCEEECCCCCCCCEEEEEC
DRTPDEIISSVKKGIYAVSFGGGQVDITSGKFVFGCTEAYLIENGKVGAPVKGAMLIGNG
CCCHHHHHHHHHCCEEEEEECCCEEEEECCCEEEECCEEEEEECCCCCCCCCCEEEECCC
PDAMKRVTMVGNDTKLDTGIGNCGKAGQWVPVGVGQPHLRMDQITVGGTQA
HHHHHEEEEECCCCEECCCCCCCCCCCCEEEECCCCCCEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]