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The map label for this gene is mcpA [H]

Identifier: 150395714

GI number: 150395714

Start: 531702

End: 533798

Strand: Direct

Name: mcpA [H]

Synonym: Smed_0489

Alternate gene names: 150395714

Gene position: 531702-533798 (Clockwise)

Preceding gene: 150395713

Following gene: 150395722

Centisome position: 14.06

GC content: 62.95

Gene sequence:

>2097_bases
TTGTCCAAACGATCGAATCTCATGACGCGCATTCTCGTTGCCGCGTCCTGCGTCGTCGTCGGCGCCTTTGCCGGCTTCTC
CGTCTATATCGATAGTCTCCAGCGCGCCACGACCACGAAAGCCGTCGAGGAGGACATCGCTTCGTCCGGTCACCAGGCAG
CGCAGAGCGTCGCCAACTGGTTGAACGGCCGCGTGACGCTGACCGCCATGGCGGCAGACGCCGCAGGACGCGTCGCAGAT
GAAGCCGCCATCCAGGGAGTGCTGAAGAACGACGTCCTGATCGGCGAGTTTATTTCGACCTATGTCGGCAATGAGAGCGG
CAAATTCATAACGTGGCCGGAATCGGAGATGCCCGAAGGATACGACCCGCGCCAGCGCCCCTGGTACCAGCAGGCGGTTA
AGGCCGATGCCCGCGTACTCACCGAGCCCTATGTCGACGCTTCCAGCGGCGACCTGATCATCAGTGCCGCGGTGCCGGTC
AGGCACGAGGGCAGGCTTTATGGCGTCACCGGCAGCGATTTCTCGCTGAAAGCACTCGTCACCATGGTCAACGGCATCGA
TGTTGGCGGCGAAGGCTTTGCCTTTCTCGCAAACAGGGACGGGCAGATCCTGGTTCATCCGAATTCGAAGCTGGTGACGA
AGACGCTTACGGACGCCTTTCCGGTCGACACGCCGGCGATCGGCAGCGGCATCATGCAAACGGAGCTGGACGGCAAGCCG
ATGCTTGTGAGTTTTGTGCCGGTGAAGGGTCTTCCGTCGGTTGAATGGTATGTCGGTTTCGCGCTTGACGCGGATGTCGC
CTATTCGGCGATCAGCCAGTTCCGCGTGGCCGCGACCATAGCCACCATCCTGGCGGTCGGCGCCATGATAGCCTTTTTGG
CTACGCTGCTGAGCCGTCTGGTGATACGGCCGGTAACCGACATGACCGGCGCCATGGAGAAGCTTGCCGCCGGCAATCTC
GAGATAGCAATCCCGGGCGAGGAGCGGCGCGACCAGATCGGTTCAATGGCAGCCGCCGTCGCGGTTTTCCGTGCCAATGC
GGTCGAGCGCAGGCGCCTCGAAGACGAGGCGGATGCCAACCGTTCGATGTCGGAACGCGAACGTCTCGAGCACGAGGCGC
AGAAGACGCGCGACGCCGCCGAGGTTCAGCACGCGGTCGATGCGTTGGCGACGGGTCTCGGAAGGTTGGCGGATGGCGAT
CTCGCCTATCGGATCGGCAATCCCTTTGCCGATCGCCTGGATCGCCTCCGGGAAGATTTCAACAATTCTGTTGCCAAGTT
GCATGACACGCTTTGTGCCGTCGGCACGAACGCGCGCGCGATCGATGCAGGTGCAAGCGAAATTCGCTCGGCCGCCGACG
ATCTTGCCCGCCGCACTGAACAACAGGCGGCATCCGTTGAAGAAACAGCGGCTGCCCTCGAAGAGATCACCACCACGGTC
CGCGATTCCGCCCACCGGGCCGAGGAAGTCGGTGCGCTGGTCGCCCGCACCCGTGCCGGCGCGGAGAAGTCCGGCGAAGT
GGTGCAGAATGCCGTCATGGCCATGCACGCCATCGAGAAGTCATCCGGCGAAATCTCGAACATCATCGGCGTCATCGATG
ACATCGCCTTCCAGACGAATCTCCTGGCGCTGAATGCCGGCGTCGAAGCGGCACGAGCCGGCGAGGCCGGCAAGGGTTTC
GCCGTCGTTGCCCAGGAAGTCCGCGAACTGGCCCAACGCTCGGCCAATGCCGCCAAGGAAATCAAGGCGCTGATCACCAC
CTCCGGAGAGCAGGTGCAATCCGGCGTGACGCTGGTCGGCGATACCGGGAGGGCGCTGCAGGCGATCGTCGCCGAAGTGC
AGGAGATCAACAAGCATGTGAGTGCGATTGTCACGGCGACTCGCGAACAGTCGACCGGTCTCCAGGAGATCAACACGGCC
GTCAACACCATGGACCAGGGCACGCAGCAAAATGCCGCCATGGTCGAACAGCAGACGGCCGCAAGCCACGGCCTTGCTTC
GGAAGCCGCGGCGCTCAATTCGCTTCTTGCGCAGTTCAGACTGGGTGAGGCGCAAACGGCCTCTTACCCGGCCACGAATC
GCCGGCGCGCAGCCTGA

Upstream 100 bases:

>100_bases
CCTTTCGCGTCGCTTTTGCGACTGATTCCTCACGCGCGGGAAAACCGTCACGAGCATGTCCGGTGCATGACGCCGGCCAC
TCCCCAGGAGAGTTCCCACC

Downstream 100 bases:

>100_bases
CGATTTTTCCGAAGCATGCACATAAAGTGAGCAGCAATCGGAGTCGCTCTGGAGAGGCCCGGCTCATCGCCGGGCCTTCT
CATTTTTCGAGCGTCGCTAC

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 698; Mature: 697

Protein sequence:

>698_residues
MSKRSNLMTRILVAASCVVVGAFAGFSVYIDSLQRATTTKAVEEDIASSGHQAAQSVANWLNGRVTLTAMAADAAGRVAD
EAAIQGVLKNDVLIGEFISTYVGNESGKFITWPESEMPEGYDPRQRPWYQQAVKADARVLTEPYVDASSGDLIISAAVPV
RHEGRLYGVTGSDFSLKALVTMVNGIDVGGEGFAFLANRDGQILVHPNSKLVTKTLTDAFPVDTPAIGSGIMQTELDGKP
MLVSFVPVKGLPSVEWYVGFALDADVAYSAISQFRVAATIATILAVGAMIAFLATLLSRLVIRPVTDMTGAMEKLAAGNL
EIAIPGEERRDQIGSMAAAVAVFRANAVERRRLEDEADANRSMSERERLEHEAQKTRDAAEVQHAVDALATGLGRLADGD
LAYRIGNPFADRLDRLREDFNNSVAKLHDTLCAVGTNARAIDAGASEIRSAADDLARRTEQQAASVEETAAALEEITTTV
RDSAHRAEEVGALVARTRAGAEKSGEVVQNAVMAMHAIEKSSGEISNIIGVIDDIAFQTNLLALNAGVEAARAGEAGKGF
AVVAQEVRELAQRSANAAKEIKALITTSGEQVQSGVTLVGDTGRALQAIVAEVQEINKHVSAIVTATREQSTGLQEINTA
VNTMDQGTQQNAAMVEQQTAASHGLASEAAALNSLLAQFRLGEAQTASYPATNRRRAA

Sequences:

>Translated_698_residues
MSKRSNLMTRILVAASCVVVGAFAGFSVYIDSLQRATTTKAVEEDIASSGHQAAQSVANWLNGRVTLTAMAADAAGRVAD
EAAIQGVLKNDVLIGEFISTYVGNESGKFITWPESEMPEGYDPRQRPWYQQAVKADARVLTEPYVDASSGDLIISAAVPV
RHEGRLYGVTGSDFSLKALVTMVNGIDVGGEGFAFLANRDGQILVHPNSKLVTKTLTDAFPVDTPAIGSGIMQTELDGKP
MLVSFVPVKGLPSVEWYVGFALDADVAYSAISQFRVAATIATILAVGAMIAFLATLLSRLVIRPVTDMTGAMEKLAAGNL
EIAIPGEERRDQIGSMAAAVAVFRANAVERRRLEDEADANRSMSERERLEHEAQKTRDAAEVQHAVDALATGLGRLADGD
LAYRIGNPFADRLDRLREDFNNSVAKLHDTLCAVGTNARAIDAGASEIRSAADDLARRTEQQAASVEETAAALEEITTTV
RDSAHRAEEVGALVARTRAGAEKSGEVVQNAVMAMHAIEKSSGEISNIIGVIDDIAFQTNLLALNAGVEAARAGEAGKGF
AVVAQEVRELAQRSANAAKEIKALITTSGEQVQSGVTLVGDTGRALQAIVAEVQEINKHVSAIVTATREQSTGLQEINTA
VNTMDQGTQQNAAMVEQQTAASHGLASEAAALNSLLAQFRLGEAQTASYPATNRRRAA
>Mature_697_residues
SKRSNLMTRILVAASCVVVGAFAGFSVYIDSLQRATTTKAVEEDIASSGHQAAQSVANWLNGRVTLTAMAADAAGRVADE
AAIQGVLKNDVLIGEFISTYVGNESGKFITWPESEMPEGYDPRQRPWYQQAVKADARVLTEPYVDASSGDLIISAAVPVR
HEGRLYGVTGSDFSLKALVTMVNGIDVGGEGFAFLANRDGQILVHPNSKLVTKTLTDAFPVDTPAIGSGIMQTELDGKPM
LVSFVPVKGLPSVEWYVGFALDADVAYSAISQFRVAATIATILAVGAMIAFLATLLSRLVIRPVTDMTGAMEKLAAGNLE
IAIPGEERRDQIGSMAAAVAVFRANAVERRRLEDEADANRSMSERERLEHEAQKTRDAAEVQHAVDALATGLGRLADGDL
AYRIGNPFADRLDRLREDFNNSVAKLHDTLCAVGTNARAIDAGASEIRSAADDLARRTEQQAASVEETAAALEEITTTVR
DSAHRAEEVGALVARTRAGAEKSGEVVQNAVMAMHAIEKSSGEISNIIGVIDDIAFQTNLLALNAGVEAARAGEAGKGFA
VVAQEVRELAQRSANAAKEIKALITTSGEQVQSGVTLVGDTGRALQAIVAEVQEINKHVSAIVTATREQSTGLQEINTAV
NTMDQGTQQNAAMVEQQTAASHGLASEAAALNSLLAQFRLGEAQTASYPATNRRRAA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=300, Percent_Identity=45.3333333333333, Blast_Score=201, Evalue=2e-52,
Organism=Escherichia coli, GI1788195, Length=272, Percent_Identity=46.3235294117647, Blast_Score=198, Evalue=1e-51,
Organism=Escherichia coli, GI1787690, Length=309, Percent_Identity=40.7766990291262, Blast_Score=191, Evalue=1e-49,
Organism=Escherichia coli, GI1788194, Length=265, Percent_Identity=44.9056603773585, Blast_Score=189, Evalue=4e-49,
Organism=Escherichia coli, GI1789453, Length=239, Percent_Identity=38.4937238493724, Blast_Score=153, Evalue=4e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 73871; Mature: 73740

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKRSNLMTRILVAASCVVVGAFAGFSVYIDSLQRATTTKAVEEDIASSGHQAAQSVANW
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
LNGRVTLTAMAADAAGRVADEAAIQGVLKNDVLIGEFISTYVGNESGKFITWPESEMPEG
HCCCEEEEEEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEECCCCCCCCC
YDPRQRPWYQQAVKADARVLTEPYVDASSGDLIISAAVPVRHEGRLYGVTGSDFSLKALV
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCEEEEECCCCCHHHHHH
TMVNGIDVGGEGFAFLANRDGQILVHPNSKLVTKTLTDAFPVDTPAIGSGIMQTELDGKP
HHHHCCCCCCCCEEEEECCCCEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCEECCCCCC
MLVSFVPVKGLPSVEWYVGFALDADVAYSAISQFRVAATIATILAVGAMIAFLATLLSRL
EEEEEECCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIRPVTDMTGAMEKLAAGNLEIAIPGEERRDQIGSMAAAVAVFRANAVERRRLEDEADAN
HHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCC
RSMSERERLEHEAQKTRDAAEVQHAVDALATGLGRLADGDLAYRIGNPFADRLDRLREDF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHH
NNSVAKLHDTLCAVGTNARAIDAGASEIRSAADDLARRTEQQAASVEETAAALEEITTTV
HHHHHHHHHHHHHCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RDSAHRAEEVGALVARTRAGAEKSGEVVQNAVMAMHAIEKSSGEISNIIGVIDDIAFQTN
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHC
LLALNAGVEAARAGEAGKGFAVVAQEVRELAQRSANAAKEIKALITTSGEQVQSGVTLVG
EEEEECCCHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHCCCEEEC
DTGRALQAIVAEVQEINKHVSAIVTATREQSTGLQEINTAVNTMDQGTQQNAAMVEQQTA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHH
ASHGLASEAAALNSLLAQFRLGEAQTASYPATNRRRAA
HHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SKRSNLMTRILVAASCVVVGAFAGFSVYIDSLQRATTTKAVEEDIASSGHQAAQSVANW
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
LNGRVTLTAMAADAAGRVADEAAIQGVLKNDVLIGEFISTYVGNESGKFITWPESEMPEG
HCCCEEEEEEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEECCCCCCCCC
YDPRQRPWYQQAVKADARVLTEPYVDASSGDLIISAAVPVRHEGRLYGVTGSDFSLKALV
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCEEEEECCCCCHHHHHH
TMVNGIDVGGEGFAFLANRDGQILVHPNSKLVTKTLTDAFPVDTPAIGSGIMQTELDGKP
HHHHCCCCCCCCEEEEECCCCEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCEECCCCCC
MLVSFVPVKGLPSVEWYVGFALDADVAYSAISQFRVAATIATILAVGAMIAFLATLLSRL
EEEEEECCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIRPVTDMTGAMEKLAAGNLEIAIPGEERRDQIGSMAAAVAVFRANAVERRRLEDEADAN
HHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCC
RSMSERERLEHEAQKTRDAAEVQHAVDALATGLGRLADGDLAYRIGNPFADRLDRLREDF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHH
NNSVAKLHDTLCAVGTNARAIDAGASEIRSAADDLARRTEQQAASVEETAAALEEITTTV
HHHHHHHHHHHHHCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RDSAHRAEEVGALVARTRAGAEKSGEVVQNAVMAMHAIEKSSGEISNIIGVIDDIAFQTN
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHC
LLALNAGVEAARAGEAGKGFAVVAQEVRELAQRSANAAKEIKALITTSGEQVQSGVTLVG
EEEEECCCHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHCCCEEEC
DTGRALQAIVAEVQEINKHVSAIVTATREQSTGLQEINTAVNTMDQGTQQNAAMVEQQTA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHH
ASHGLASEAAALNSLLAQFRLGEAQTASYPATNRRRAA
HHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]