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The map label for this gene is yghX [H]

Identifier: 150395606

GI number: 150395606

Start: 408389

End: 409264

Strand: Direct

Name: yghX [H]

Synonym: Smed_0381

Alternate gene names: 150395606

Gene position: 408389-409264 (Clockwise)

Preceding gene: 150395605

Following gene: 150395608

Centisome position: 10.8

GC content: 61.53

Gene sequence:

>876_bases
ATGAACAAACCTGTCATTACCCAGGCGATGATCGATGCCTATGACGAGTATACGCATCTCACCTTGGACCGCCGCCGCTT
CATGGAGAAACTGACGGCGCTTGCCGGGACGGCTGCCGCCGCCGCTGCAATCGCGCCGATGCTGGCTGCCAACAGCGCCA
AAGCCGAAATAATCGCCGAAACGGACGAGCGAATCAAAGGCGAGGACATCACCTATCCTGGCGGCGATGGCAAAATGAAG
GGTTATCTCGTGAAGCCCGCCGAAATGTCCGGCAAGCTTCCCGCCGTCATCGTCATCCACGAGAATCGCGGCCTCAATCC
GCACATCAGAGACGTTGCACGCCGCATGGCGCTCGAAGGTTTTCTGGCACTTGCTCCCGATTTCCTTTCGCCGGAGGGGG
GAACCCCGGGCGATGAGGACAAGGCGCGCGAGATGATCGGCGCGCTCGATGCAAGCGCTACGAATGCCAACGCCGTCGCC
ACAGTGGCCTTCCTGAAGGGTCATGCGGAAAGCACCGCCAATGTGGGGGCGATCGGCTTTTGCTGGGGCGGCGGTCTCGT
CAACAGGCTTGCCGTGAACGCGCCTGACCTCAAGGCCGGCGTCGCCTATTACGGCGCCCAGCCGAAAGCCGAGGACGTGC
CGAAGATCAAGGCTGCGCTGCTGCTGCATTATGCCGGGCTCGATGAGCGCATCAATGCCGGCATCGAGGCCTACCGCAAG
GCGTTGACGGAAAACGGCAAGGACGCCACGATTCACGTCTATGAGGGCGTGAACCACGCTTTCAACAACGACACCTCGGC
AGCCCGTTACGACAAGGAGGCGGCCGACCTTGCCTGGCAGCGGACCGTCGAATTCCTGAAGGCGAAGCTCGCTTAG

Upstream 100 bases:

>100_bases
ATGGCGATGAGCTGAGGTAACGCAGTTTTGTAAGTCCGTGACCGCGCCGCTGACCTATTCTGTCCAGCGGCTTTCATCTG
CCACAGCCCAGGAGAGCGTC

Downstream 100 bases:

>100_bases
TCATACGGCCGGTTTGGGCGCAGATTTCACTGCGCCTCTATCGGCCGGGATAGCGCCCTGCGAGACCTCGCGGGCACAGG
TCGATATGGCGTCTGCAAGC

Product: carboxymethylenebutenolidase

Products: 4-oxohex-2-enedioate

Alternate protein names: NA

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MNKPVITQAMIDAYDEYTHLTLDRRRFMEKLTALAGTAAAAAAIAPMLAANSAKAEIIAETDERIKGEDITYPGGDGKMK
GYLVKPAEMSGKLPAVIVIHENRGLNPHIRDVARRMALEGFLALAPDFLSPEGGTPGDEDKAREMIGALDASATNANAVA
TVAFLKGHAESTANVGAIGFCWGGGLVNRLAVNAPDLKAGVAYYGAQPKAEDVPKIKAALLLHYAGLDERINAGIEAYRK
ALTENGKDATIHVYEGVNHAFNNDTSAARYDKEAADLAWQRTVEFLKAKLA

Sequences:

>Translated_291_residues
MNKPVITQAMIDAYDEYTHLTLDRRRFMEKLTALAGTAAAAAAIAPMLAANSAKAEIIAETDERIKGEDITYPGGDGKMK
GYLVKPAEMSGKLPAVIVIHENRGLNPHIRDVARRMALEGFLALAPDFLSPEGGTPGDEDKAREMIGALDASATNANAVA
TVAFLKGHAESTANVGAIGFCWGGGLVNRLAVNAPDLKAGVAYYGAQPKAEDVPKIKAALLLHYAGLDERINAGIEAYRK
ALTENGKDATIHVYEGVNHAFNNDTSAARYDKEAADLAWQRTVEFLKAKLA
>Mature_291_residues
MNKPVITQAMIDAYDEYTHLTLDRRRFMEKLTALAGTAAAAAAIAPMLAANSAKAEIIAETDERIKGEDITYPGGDGKMK
GYLVKPAEMSGKLPAVIVIHENRGLNPHIRDVARRMALEGFLALAPDFLSPEGGTPGDEDKAREMIGALDASATNANAVA
TVAFLKGHAESTANVGAIGFCWGGGLVNRLAVNAPDLKAGVAYYGAQPKAEDVPKIKAALLLHYAGLDERINAGIEAYRK
ALTENGKDATIHVYEGVNHAFNNDTSAARYDKEAADLAWQRTVEFLKAKLA

Specific function: Unknown

COG id: COG0412

COG function: function code Q; Dienelactone hydrolase and related enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI20270371, Length=217, Percent_Identity=29.4930875576037, Blast_Score=75, Evalue=5e-14,
Organism=Escherichia coli, GI48994982, Length=254, Percent_Identity=32.6771653543307, Blast_Score=120, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002925 [H]

Pfam domain/function: PF01738 DLH [H]

EC number: 3.1.1.45

Molecular weight: Translated: 31019; Mature: 31019

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKPVITQAMIDAYDEYTHLTLDRRRFMEKLTALAGTAAAAAAIAPMLAANSAKAEIIAE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEC
TDERIKGEDITYPGGDGKMKGYLVKPAEMSGKLPAVIVIHENRGLNPHIRDVARRMALEG
CHHHCCCCCCCCCCCCCCCCEEEECCHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHH
FLALAPDFLSPEGGTPGDEDKAREMIGALDASATNANAVATVAFLKGHAESTANVGAIGF
HHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCEEEE
CWGGGLVNRLAVNAPDLKAGVAYYGAQPKAEDVPKIKAALLLHYAGLDERINAGIEAYRK
EECCHHHHHHCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHH
ALTENGKDATIHVYEGVNHAFNNDTSAARYDKEAADLAWQRTVEFLKAKLA
HHHCCCCCCEEEEECCCCHHCCCCCCHHHHCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNKPVITQAMIDAYDEYTHLTLDRRRFMEKLTALAGTAAAAAAIAPMLAANSAKAEIIAE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEC
TDERIKGEDITYPGGDGKMKGYLVKPAEMSGKLPAVIVIHENRGLNPHIRDVARRMALEG
CHHHCCCCCCCCCCCCCCCCEEEECCHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHH
FLALAPDFLSPEGGTPGDEDKAREMIGALDASATNANAVATVAFLKGHAESTANVGAIGF
HHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCEEEE
CWGGGLVNRLAVNAPDLKAGVAYYGAQPKAEDVPKIKAALLLHYAGLDERINAGIEAYRK
EECCHHHHHHCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHH
ALTENGKDATIHVYEGVNHAFNNDTSAARYDKEAADLAWQRTVEFLKAKLA
HHHCCCCCCEEEEECCCCHHCCCCCCHHHHCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 4-carboxymethylenebut-2-en-4-olide; H2O

Specific reaction: 4-carboxymethylenebut-2-en-4-olide + H2O = 4-oxohex-2-enedioate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]