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The map label for this gene is ctrA [H]

Identifier: 150395425

GI number: 150395425

Start: 225195

End: 226382

Strand: Direct

Name: ctrA [H]

Synonym: Smed_0198

Alternate gene names: 150395425

Gene position: 225195-226382 (Clockwise)

Preceding gene: 150395419

Following gene: 150395426

Centisome position: 5.95

GC content: 61.62

Gene sequence:

>1188_bases
GTGAAACGAGTGACTGCCCTTCTGCTCTGTACCGCGCTTGCGGGATGCCAGGCCGTACCGGGCGAGGGCCCTTTGACAAC
CGATATCGTGTCGGATGCCGGCCAGTCCGGATCCGAGATCGGCAGAAGGAATGCCACGGTTTTTGATATCGTCGATGTCG
ACGGGCAGTCGGCGCGGCTTGTTTCCGAGTATGTTTCCACAACCCTCAGCCGCCGCTTCGGGATTGGCGGTGGCGTCGGC
CAAGTAGTCATCGGCATCGGTGACCAGTTGAAGGTCACGATCTTCGAGGCGGGCAGCGACGGCCTGTTTTCCACAACTGA
ATCGAAGCAGACGAGCATCGACCTCGTCGTCCAGCCCGATGGCAAGGCCGCGATTCCCTATGTTGGATCTGTCCGCTTTG
CCGGTCTGACGCTCGAGCAGGCGCGGCAGGCGATCCTGGAGGCGCTGAAGCAGAAGGCGGTGGAACCGGATGTGATCGTG
ACGTCGACATCGACGGCATCGCGCAACGTGACTGTCTCCGGCGCGGTCGGCCGCCCCTCGGTCGTGCCGCTCAATCTCGT
CAGCGAGACGATCAATGAGGTGATCGCCAAGGCGGGCGGCCCCTCGGCGCAGCCTTACGAGACCTACGTCACCCTCGTGC
GCGGCAAGAAGACCGGCACGGTCCTGCTGAAGTCGATGATTGAAAGCCCTTCGGAAAACATTCACGTAAAGCCCGGCGAC
CAGATCTTCGTTACGCGCGATCCGCGCACCTTCACGGTCCTCGGCCAGGTCCGGGCCAATCAGCGCGTCGAGTTCGGCGC
CAACGACCTCAACCTGCTCGAAGCCGTGGCGCTCGGAGGCGGCGGCTCGGATCGCACGGTGGACGCCAAGGGCTACTTCG
TCTTCCGGTTCGAGGAGCCGGACATCGTCATGAGCCTGCTTGGGCAGGAGCGTTTCCATCAGATGCTGAGCAAGGGCATG
AAAGCCGATCGCGTGGGGCGCTATCCCATCGTCTACCGGTTCGACATGACCAACCCGGACAGTCTCATCGTCGGCCAGAC
CTTCCCGATCAAGAATCGCGACGTCATCTACGCCTCGCGCCATCCCTCGGTCGATATCACGAAATTCCTCGACTTCGTCG
CACGTCCGATCGGTATCGTGAATTCCGGCGTAAACATCGCCGACAATATCGACGACTTCAGAAACTGA

Upstream 100 bases:

>100_bases
CGACCTTTGTGCTTTTCAGTGACCGGCGGATTCCCTGCCGGGAAAATGCGGCGCAGATATCTGTTTGGATTCATTGCTGT
GCCGAAGACGGAGTGTCGTA

Downstream 100 bases:

>100_bases
GGCTGCAGGGGCAACTGTCACCCCCTTGCGCCGCGATGCTGCGATGTTCTGCAGCATGCCGCCAGAATCCCGCGGCGTGC
GCCGAACATGCTTGCCGCCG

Product: polysaccharide export protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MKRVTALLLCTALAGCQAVPGEGPLTTDIVSDAGQSGSEIGRRNATVFDIVDVDGQSARLVSEYVSTTLSRRFGIGGGVG
QVVIGIGDQLKVTIFEAGSDGLFSTTESKQTSIDLVVQPDGKAAIPYVGSVRFAGLTLEQARQAILEALKQKAVEPDVIV
TSTSTASRNVTVSGAVGRPSVVPLNLVSETINEVIAKAGGPSAQPYETYVTLVRGKKTGTVLLKSMIESPSENIHVKPGD
QIFVTRDPRTFTVLGQVRANQRVEFGANDLNLLEAVALGGGGSDRTVDAKGYFVFRFEEPDIVMSLLGQERFHQMLSKGM
KADRVGRYPIVYRFDMTNPDSLIVGQTFPIKNRDVIYASRHPSVDITKFLDFVARPIGIVNSGVNIADNIDDFRN

Sequences:

>Translated_395_residues
MKRVTALLLCTALAGCQAVPGEGPLTTDIVSDAGQSGSEIGRRNATVFDIVDVDGQSARLVSEYVSTTLSRRFGIGGGVG
QVVIGIGDQLKVTIFEAGSDGLFSTTESKQTSIDLVVQPDGKAAIPYVGSVRFAGLTLEQARQAILEALKQKAVEPDVIV
TSTSTASRNVTVSGAVGRPSVVPLNLVSETINEVIAKAGGPSAQPYETYVTLVRGKKTGTVLLKSMIESPSENIHVKPGD
QIFVTRDPRTFTVLGQVRANQRVEFGANDLNLLEAVALGGGGSDRTVDAKGYFVFRFEEPDIVMSLLGQERFHQMLSKGM
KADRVGRYPIVYRFDMTNPDSLIVGQTFPIKNRDVIYASRHPSVDITKFLDFVARPIGIVNSGVNIADNIDDFRN
>Mature_395_residues
MKRVTALLLCTALAGCQAVPGEGPLTTDIVSDAGQSGSEIGRRNATVFDIVDVDGQSARLVSEYVSTTLSRRFGIGGGVG
QVVIGIGDQLKVTIFEAGSDGLFSTTESKQTSIDLVVQPDGKAAIPYVGSVRFAGLTLEQARQAILEALKQKAVEPDVIV
TSTSTASRNVTVSGAVGRPSVVPLNLVSETINEVIAKAGGPSAQPYETYVTLVRGKKTGTVLLKSMIESPSENIHVKPGD
QIFVTRDPRTFTVLGQVRANQRVEFGANDLNLLEAVALGGGGSDRTVDAKGYFVFRFEEPDIVMSLLGQERFHQMLSKGM
KADRVGRYPIVYRFDMTNPDSLIVGQTFPIKNRDVIYASRHPSVDITKFLDFVARPIGIVNSGVNIADNIDDFRN

Specific function: Involved in transport of capsular polysaccharides to the cell surface. May function as a membrane anchor for capsular polysaccharides. Possible porin properties [H]

COG id: COG1596

COG function: function code M; Periplasmic protein involved in polysaccharide export

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BexD/CtrA/VexA family [H]

Homologues:

Organism=Escherichia coli, GI1788376, Length=408, Percent_Identity=24.0196078431373, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1787218, Length=283, Percent_Identity=24.7349823321555, Blast_Score=78, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003715 [H]

Pfam domain/function: PF02563 Poly_export [H]

EC number: NA

Molecular weight: Translated: 42338; Mature: 42338

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRVTALLLCTALAGCQAVPGEGPLTTDIVSDAGQSGSEIGRRNATVFDIVDVDGQSARL
CCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCHHHHCCCCEEEEEEECCCCHHHH
VSEYVSTTLSRRFGIGGGVGQVVIGIGDQLKVTIFEAGSDGLFSTTESKQTSIDLVVQPD
HHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEEEEECCCCCCEECCCCCCCEEEEEECCC
GKAAIPYVGSVRFAGLTLEQARQAILEALKQKAVEPDVIVTSTSTASRNVTVSGAVGRPS
CCEECCCCCCEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEECCCCCCC
VVPLNLVSETINEVIAKAGGPSAQPYETYVTLVRGKKTGTVLLKSMIESPSENIHVKPGD
EEEHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCHHHHHHHHHHCCCCCCEEECCCC
QIFVTRDPRTFTVLGQVRANQRVEFGANDLNLLEAVALGGGGSDRTVDAKGYFVFRFEEP
EEEEEECCCEEEEEEECCCCCEEEECCCCHHHHHHHEECCCCCCCEEECCCEEEEEECCC
DIVMSLLGQERFHQMLSKGMKADRVGRYPIVYRFDMTNPDSLIVGQTFPIKNRDVIYASR
HHHHHHHCHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCEEEECCCCCCCCCEEEECC
HPSVDITKFLDFVARPIGIVNSGVNIADNIDDFRN
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHCC
>Mature Secondary Structure
MKRVTALLLCTALAGCQAVPGEGPLTTDIVSDAGQSGSEIGRRNATVFDIVDVDGQSARL
CCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCHHHHCCCCEEEEEEECCCCHHHH
VSEYVSTTLSRRFGIGGGVGQVVIGIGDQLKVTIFEAGSDGLFSTTESKQTSIDLVVQPD
HHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEEEEECCCCCCEECCCCCCCEEEEEECCC
GKAAIPYVGSVRFAGLTLEQARQAILEALKQKAVEPDVIVTSTSTASRNVTVSGAVGRPS
CCEECCCCCCEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEECCCCCCC
VVPLNLVSETINEVIAKAGGPSAQPYETYVTLVRGKKTGTVLLKSMIESPSENIHVKPGD
EEEHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCHHHHHHHHHHCCCCCCEEECCCC
QIFVTRDPRTFTVLGQVRANQRVEFGANDLNLLEAVALGGGGSDRTVDAKGYFVFRFEEP
EEEEEECCCEEEEEEECCCCCEEEECCCCHHHHHHHEECCCCCCCEEECCCEEEEEECCC
DIVMSLLGQERFHQMLSKGMKADRVGRYPIVYRFDMTNPDSLIVGQTFPIKNRDVIYASR
HHHHHHHCHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCEEEECCCCCCCCCEEEECC
HPSVDITKFLDFVARPIGIVNSGVNIADNIDDFRN
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1659649; 1371768; 10710307 [H]