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The map label for this gene is iolG [H]

Identifier: 150395417

GI number: 150395417

Start: 209176

End: 210171

Strand: Direct

Name: iolG [H]

Synonym: Smed_0190

Alternate gene names: 150395417

Gene position: 209176-210171 (Clockwise)

Preceding gene: 150395416

Following gene: 150395418

Centisome position: 5.53

GC content: 63.65

Gene sequence:

>996_bases
ATGACACTCAAGATCGGTTGGATCGGCTGTGGCGTGCACGCCAGCCAGATGCTGCTTCCACAGCTCGTTCGCCATGACAT
CCAGGTGACTGCGCTCTGCGACATCGATGCCGCTCGCCTTGCTTCTGCAGGGCGGCAGTTCGGCGTTTCGAACCTGACGG
GCGATGCGGAAGAACTCATCCGCCGCTCCGACATAGACGCGGTCGGCATGGCCGTCGGGCCGGACCAGCACCTGCTATTC
GGCAAGATGGCTCTGGAGCGGGGCCTGCCGGTCTTCATGGAAAAGCCGCCGTCCGGCAGCGCGGAAGGCGCGCGCGAATT
GCTCGCCGCCTCGGAAAGGTCCGGCAAGCCATTGCTCGTCGGCTTCATGAAGCGGTATTCCGCCGGAAACAGGATTGCGG
CGAACATCTTGCGCTCGGGCCGGTTCGGCCCCGTCTATGGCCTCACCGGCTACTACATGACGGCGCCGGCCTATTTCGCC
GGCAATGTCGACTACACCGGCTTCTTTCTGCACCATTGCGTGCACTATATGGACCTCGTTTCCTTCCTCGTCTCGCCTGT
TACGAAACTGACGGCGCGCAAGGTCGAAAAGGATCGCGGCAAGGTCCTCTTCCACGTGCATTTCGATTTCGAATGCGGCG
CGATCGGCACGATTGCGATGGGCACGGCCCAGTCGCGCGGCGCGCCGGTGGAGCGCCTGGAGATCATGGGCGACCACCAG
CGCATCGAGGTGGATAATGTCATCGAGGTGCGCTGGAACAGAAATCCGCCCTTCAAGGTCGATGATCCGGCTGCCACACT
TGACGGCGCGGTCGACACGCTGACCTGGAAGCCGAACTTCACCGCAGCCGCCAACGAGGACCCGAAGGGCTATCATGCGC
TGCTCGCCGACGTCATTCCGGCGCTTGCAGGCAAGCAGACGCCGGCGCCGACCATCCGCGAGGGCGTGATCGCCATGGAA
CGCCTGGAAACGCTGCGGCGCGCGCTCGCGCTCTAA

Upstream 100 bases:

>100_bases
CCTTTGCCCAGTGGCGCCCGCCGCACGAGGACGAGAGCGAACGCCTCGCCGCCAGCGCCGAATTCATCAAGTCCCACATC
CTGCTTACGGAATATCGTCG

Downstream 100 bases:

>100_bases
AGGCCGGGCTGCTCGATGAGGCGCCGCTTTACGCTCCCGGTCTGGACGCTGCCTTTCGAGTATAGCTGAGTGTCGGTCAA
GCATTCTTGTGCTATGGCAG

Product: oxidoreductase domain-containing protein

Products: NA

Alternate protein names: Myo-inositol 2-dehydrogenase; MI 2-dehydrogenase [H]

Number of amino acids: Translated: 331; Mature: 330

Protein sequence:

>331_residues
MTLKIGWIGCGVHASQMLLPQLVRHDIQVTALCDIDAARLASAGRQFGVSNLTGDAEELIRRSDIDAVGMAVGPDQHLLF
GKMALERGLPVFMEKPPSGSAEGARELLAASERSGKPLLVGFMKRYSAGNRIAANILRSGRFGPVYGLTGYYMTAPAYFA
GNVDYTGFFLHHCVHYMDLVSFLVSPVTKLTARKVEKDRGKVLFHVHFDFECGAIGTIAMGTAQSRGAPVERLEIMGDHQ
RIEVDNVIEVRWNRNPPFKVDDPAATLDGAVDTLTWKPNFTAAANEDPKGYHALLADVIPALAGKQTPAPTIREGVIAME
RLETLRRALAL

Sequences:

>Translated_331_residues
MTLKIGWIGCGVHASQMLLPQLVRHDIQVTALCDIDAARLASAGRQFGVSNLTGDAEELIRRSDIDAVGMAVGPDQHLLF
GKMALERGLPVFMEKPPSGSAEGARELLAASERSGKPLLVGFMKRYSAGNRIAANILRSGRFGPVYGLTGYYMTAPAYFA
GNVDYTGFFLHHCVHYMDLVSFLVSPVTKLTARKVEKDRGKVLFHVHFDFECGAIGTIAMGTAQSRGAPVERLEIMGDHQ
RIEVDNVIEVRWNRNPPFKVDDPAATLDGAVDTLTWKPNFTAAANEDPKGYHALLADVIPALAGKQTPAPTIREGVIAME
RLETLRRALAL
>Mature_330_residues
TLKIGWIGCGVHASQMLLPQLVRHDIQVTALCDIDAARLASAGRQFGVSNLTGDAEELIRRSDIDAVGMAVGPDQHLLFG
KMALERGLPVFMEKPPSGSAEGARELLAASERSGKPLLVGFMKRYSAGNRIAANILRSGRFGPVYGLTGYYMTAPAYFAG
NVDYTGFFLHHCVHYMDLVSFLVSPVTKLTARKVEKDRGKVLFHVHFDFECGAIGTIAMGTAQSRGAPVERLEIMGDHQR
IEVDNVIEVRWNRNPPFKVDDPAATLDGAVDTLTWKPNFTAAANEDPKGYHALLADVIPALAGKQTPAPTIREGVIAMER
LETLRRALAL

Specific function: Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) [H]

COG id: COG0673

COG function: function code R; Predicted dehydrogenases and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: =1.1.1.18 [H]

Molecular weight: Translated: 36025; Mature: 35894

Theoretical pI: Translated: 7.66; Mature: 7.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLKIGWIGCGVHASQMLLPQLVRHDIQVTALCDIDAARLASAGRQFGVSNLTGDAEELI
CEEEEEEEECCCHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHCCCCCCCCCHHHHH
RRSDIDAVGMAVGPDQHLLFGKMALERGLPVFMEKPPSGSAEGARELLAASERSGKPLLV
HHCCCCCCCEEECCCCHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHCCCCCCHHH
GFMKRYSAGNRIAANILRSGRFGPVYGLTGYYMTAPAYFAGNVDYTGFFLHHCVHYMDLV
HHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCEEECCEEEECCCCHHHHHHHHHHHHHHHH
SFLVSPVTKLTARKVEKDRGKVLFHVHFDFECGAIGTIAMGTAQSRGAPVERLEIMGDHQ
HHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEEEECCCCCCCCCHHHHHHCCCCC
RIEVDNVIEVRWNRNPPFKVDDPAATLDGAVDTLTWKPNFTAAANEDPKGYHALLADVIP
EEEECCEEEEEECCCCCCCCCCCCHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHH
ALAGKQTPAPTIREGVIAMERLETLRRALAL
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TLKIGWIGCGVHASQMLLPQLVRHDIQVTALCDIDAARLASAGRQFGVSNLTGDAEELI
EEEEEEEECCCHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHCCCCCCCCCHHHHH
RRSDIDAVGMAVGPDQHLLFGKMALERGLPVFMEKPPSGSAEGARELLAASERSGKPLLV
HHCCCCCCCEEECCCCHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHCCCCCCHHH
GFMKRYSAGNRIAANILRSGRFGPVYGLTGYYMTAPAYFAGNVDYTGFFLHHCVHYMDLV
HHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCEEECCEEEECCCCHHHHHHHHHHHHHHHH
SFLVSPVTKLTARKVEKDRGKVLFHVHFDFECGAIGTIAMGTAQSRGAPVERLEIMGDHQ
HHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEEEECCCCCCCCCHHHHHHCCCCC
RIEVDNVIEVRWNRNPPFKVDDPAATLDGAVDTLTWKPNFTAAANEDPKGYHALLADVIP
EEEECCEEEEEECCCCCCCCCCCCHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHH
ALAGKQTPAPTIREGVIAMERLETLRRALAL
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA