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The map label for this gene is hslO [H]

Identifier: 150395357

GI number: 150395357

Start: 143372

End: 144364

Strand: Direct

Name: hslO [H]

Synonym: Smed_0129

Alternate gene names: 150395357

Gene position: 143372-144364 (Clockwise)

Preceding gene: 150395356

Following gene: 150395360

Centisome position: 3.79

GC content: 62.94

Gene sequence:

>993_bases
ATGACAGAAACAGCGCCGGGACTCGGCGAGTTCGATTTTGCCGGTGACGATCAGGTCGTGCCCTTCCAGGTCGAGGGGCT
CGACGTGCGCGGCCGCGCCGTTCAACTTGGTCCGATGCTGGATGCAATTCTCGAGCGGCACAGCTATCCGCTTCCGGTAG
CCCGGCTTGTCGCCGAAACCGTGGTGCTGACAGTGCTGCTCGGGACGTCCCTTAAATTCGAAGGCAAGCTGATCGTCCAG
ACACAGGGTGATGGGCCGGTTGACCTCGTTGTCGCGGACTTCTCGACGCCGGACCGCGTTCGCGCCTATGCCCGCTACGA
TGAGGAGGCGCTTGCCGCTGCCGAGAAAAACGGGCGGTCCCAGCCTCACGAGCTGCTGGGTAACGGCATTCTCGCCTTCA
CCATCGACCAGGGTGCGCATACGCAGCGCTACCAGGGCATCGTCGCGCTTGACGGAGCGACGCTCGAGGAGATCGCGGGC
GCCTATTTCCGGCAATCGGAGCAGATACCGACCAGGGTGCGTCTCGCCGTTGCCGAGCTTCTCGACAAGGACGAGAACGG
CAAGCCTCGGCATCGCTGGCGCGCCGGCGGCATGGTCGCGCAGTTCCTGCCCGATGCGCCCGACCGGATGCGACAGCCGG
ATCTGCCGGGCGGCGACGGCGAGGCAGACATCGAGGATATCTTTGACGAGGACGATCTATGGGCGGAAGCCAAGGTGATG
GTCGAGACGATCGACACCGATGAGCTCACCGATCCCACAGTCGGAACCGAAAGACTGCTGTACCGGCTGTTTCACGAGCG
CGGTGTTCGCGTCTATGAACCGCAGGCGGTCTATGACCGCTGCAGCTGCTCGCGCGAGAAAATCAGGGATGTTCTGACTG
GGCTCGGCGACGAAGATATCGAAAGCAGTGTCGAGGACGGGCTGATCAAGGTCACCTGCGAGTTCTGTTCGACGACCTAC
CGCTTCGAGGCGAGTGAGGTCCGTACCCAGTGA

Upstream 100 bases:

>100_bases
CAGTTTCCGTCCGGAGCCCGAATGGAGTTTGAAAGGGCCATGGCCACAATCCCCGGATTGGATCAATTCGGATGATCATG
GTCGAGGCAAGGAGCAAGCA

Downstream 100 bases:

>100_bases
GAAGCTGCCCAGGCTTCAAGTCTCCCGTGCCCGGCAGGCGGTCGCTTGCGGGGAGAAGGAGGCCGGCAGGCCGCATGAGG
GCGCTTTTCTAGTTAAGGGT

Product: Hsp33-like chaperonin

Products: NA

Alternate protein names: Heat shock protein 33 homolog; HSP33 [H]

Number of amino acids: Translated: 330; Mature: 329

Protein sequence:

>330_residues
MTETAPGLGEFDFAGDDQVVPFQVEGLDVRGRAVQLGPMLDAILERHSYPLPVARLVAETVVLTVLLGTSLKFEGKLIVQ
TQGDGPVDLVVADFSTPDRVRAYARYDEEALAAAEKNGRSQPHELLGNGILAFTIDQGAHTQRYQGIVALDGATLEEIAG
AYFRQSEQIPTRVRLAVAELLDKDENGKPRHRWRAGGMVAQFLPDAPDRMRQPDLPGGDGEADIEDIFDEDDLWAEAKVM
VETIDTDELTDPTVGTERLLYRLFHERGVRVYEPQAVYDRCSCSREKIRDVLTGLGDEDIESSVEDGLIKVTCEFCSTTY
RFEASEVRTQ

Sequences:

>Translated_330_residues
MTETAPGLGEFDFAGDDQVVPFQVEGLDVRGRAVQLGPMLDAILERHSYPLPVARLVAETVVLTVLLGTSLKFEGKLIVQ
TQGDGPVDLVVADFSTPDRVRAYARYDEEALAAAEKNGRSQPHELLGNGILAFTIDQGAHTQRYQGIVALDGATLEEIAG
AYFRQSEQIPTRVRLAVAELLDKDENGKPRHRWRAGGMVAQFLPDAPDRMRQPDLPGGDGEADIEDIFDEDDLWAEAKVM
VETIDTDELTDPTVGTERLLYRLFHERGVRVYEPQAVYDRCSCSREKIRDVLTGLGDEDIESSVEDGLIKVTCEFCSTTY
RFEASEVRTQ
>Mature_329_residues
TETAPGLGEFDFAGDDQVVPFQVEGLDVRGRAVQLGPMLDAILERHSYPLPVARLVAETVVLTVLLGTSLKFEGKLIVQT
QGDGPVDLVVADFSTPDRVRAYARYDEEALAAAEKNGRSQPHELLGNGILAFTIDQGAHTQRYQGIVALDGATLEEIAGA
YFRQSEQIPTRVRLAVAELLDKDENGKPRHRWRAGGMVAQFLPDAPDRMRQPDLPGGDGEADIEDIFDEDDLWAEAKVMV
ETIDTDELTDPTVGTERLLYRLFHERGVRVYEPQAVYDRCSCSREKIRDVLTGLGDEDIESSVEDGLIKVTCEFCSTTYR
FEASEVRTQ

Specific function: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress [H]

COG id: COG1281

COG function: function code O; Disulfide bond chaperones of the HSP33 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HSP33 family [H]

Homologues:

Organism=Escherichia coli, GI87082260, Length=312, Percent_Identity=36.5384615384615, Blast_Score=174, Evalue=5e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000397
- InterPro:   IPR016154
- InterPro:   IPR016153 [H]

Pfam domain/function: PF01430 HSP33 [H]

EC number: NA

Molecular weight: Translated: 36561; Mature: 36430

Theoretical pI: Translated: 4.24; Mature: 4.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTETAPGLGEFDFAGDDQVVPFQVEGLDVRGRAVQLGPMLDAILERHSYPLPVARLVAET
CCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCEEEHHHHHHHHHHHCCCCCHHHHHHHHH
VVLTVLLGTSLKFEGKLIVQTQGDGPVDLVVADFSTPDRVRAYARYDEEALAAAEKNGRS
HHHHHHHCCCEEECCEEEEEECCCCCEEEEEECCCCHHHHHHHHHCCHHHHHHHHHCCCC
QPHELLGNGILAFTIDQGAHTQRYQGIVALDGATLEEIAGAYFRQSEQIPTRVRLAVAEL
CCHHHHHCCEEEEEECCCCCHHHHCCEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHH
LDKDENGKPRHRWRAGGMVAQFLPDAPDRMRQPDLPGGDGEADIEDIFDEDDLWAEAKVM
HCCCCCCCCHHHHHHCCCHHHHCCCCHHHHCCCCCCCCCCCCCHHHHCCCCCCHHHHEEE
VETIDTDELTDPTVGTERLLYRLFHERGVRVYEPQAVYDRCSCSREKIRDVLTGLGDEDI
EEECCCCCCCCCCCCHHHHHHHHHHHCCCEEECCHHHHHHHCCCHHHHHHHHHCCCCHHH
ESSVEDGLIKVTCEFCSTTYRFEASEVRTQ
HHHHHCCEEEEEEHHHCCEEEEEHHHHCCC
>Mature Secondary Structure 
TETAPGLGEFDFAGDDQVVPFQVEGLDVRGRAVQLGPMLDAILERHSYPLPVARLVAET
CCCCCCCCCCCCCCCCCEEEEEECCCCCCCCEEEHHHHHHHHHHHCCCCCHHHHHHHHH
VVLTVLLGTSLKFEGKLIVQTQGDGPVDLVVADFSTPDRVRAYARYDEEALAAAEKNGRS
HHHHHHHCCCEEECCEEEEEECCCCCEEEEEECCCCHHHHHHHHHCCHHHHHHHHHCCCC
QPHELLGNGILAFTIDQGAHTQRYQGIVALDGATLEEIAGAYFRQSEQIPTRVRLAVAEL
CCHHHHHCCEEEEEECCCCCHHHHCCEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHH
LDKDENGKPRHRWRAGGMVAQFLPDAPDRMRQPDLPGGDGEADIEDIFDEDDLWAEAKVM
HCCCCCCCCHHHHHHCCCHHHHCCCCHHHHCCCCCCCCCCCCCHHHHCCCCCCHHHHEEE
VETIDTDELTDPTVGTERLLYRLFHERGVRVYEPQAVYDRCSCSREKIRDVLTGLGDEDI
EEECCCCCCCCCCCCHHHHHHHHHHHCCCEEECCHHHHHHHCCCHHHHHHHHHCCCCHHH
ESSVEDGLIKVTCEFCSTTYRFEASEVRTQ
HHHHHCCEEEEEEHHHCCEEEEEHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA