Click here to switch to the map view.

The map label for this gene is dxs [C]

Identifier: 150401927

GI number: 150401927

Start: 1566483

End: 1567427

Strand: Direct

Name: dxs [C]

Synonym: Maeo_1505

Alternate gene names: 150401927

Gene position: 1566483-1567427 (Clockwise)

Preceding gene: 150401926

Following gene: 150401928

Centisome position: 99.81

GC content: 34.29

Gene sequence:

>945_bases
ATGGATTACAAAATAGGAGATAAAAAAGCTATGAGAAATGCCTACGGAGAAACCCTTGTTGAGTTGGGTAAAGAATATCC
AAATTTAGTTGTTCTTGATTCGGATTTATCGGGTTCCACGAAAACGGCAATGTTTGCAAAACAATATCCTGATAGATTTT
TTAATGCAGGAATAGCAGAGCAAAATATGATTGGTATGGCATCAGGACTTTCATTAACTGGAAAAATAGTATTTGCTTCC
TCATTTGCAATGTTTGCCAGTGGAAGGCCATGGGAACAAATTAGAAATTCGGTGGCATATGCAAATTTAAATGTAAAAAT
TGCAGCTACACATAGTGGTATAACTGTTGGGGAGGACGGGGCAACCCATCAAATGACCGAAGATATTGCCATAATGAGAG
CAATTCCAAACATGATTGTAATCGCACCCTCAGACTATTATGAAGCAAAAAGTGTCATAAGATGGAGTGCAACCTATGAC
GGTCCAGTATATATTAGGATGCCAAGGGGAGATACTGAAACAATATTCAAAGATGAAGAAGATGCTAAATTTGCATTTGG
AAAAGCAAAAATCATAAAAGACGGAAAAGATTTAACAATAATAGCAACGGGGGAAATAATTCCAGAGGCAATTAAAGCAT
CAGAAATATTAAAAGAAAAAGGTATAGATGCAGAAGTAATAATAATGGCAACCATAAAACCAATTGACGAACAGGCAGTA
ATTAATTCCAATGATTTTGTAGTTTCTGTTGAAGACCACAATATAATTGGAGGGCTTGGCGGTGCAATATCTGAAGTAAT
AGCAAGTAATGGACTTAACAAAAAACTTTTAAGAATTGGAATTAATGATGAGTTCGGTGAATCTGGTAAAGCTAATGAGC
TTTTAAAATACTATAAACTTGATAGTGAAAGTATTGCAAAAAAAATAATTGAAGAATTTAAATAA

Upstream 100 bases:

>100_bases
GCAGACTGCCTTATTGCAGCATCTGCCATATATAATCAAGAAGATGTTGGTGGAGCAGTGAAATTATTAAAAGAATCGGC
AAAATTCAAAAGGTGAAATA

Downstream 100 bases:

>100_bases
AAACTATTAGTTTTTATGGCCAATATCAAATAATTTTTTTATTTATCATTACTTATTATTATTATTATTTATTACTATTT
TATCCTTATCTTTGGAGATA

Product: transketolase central region

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MDYKIGDKKAMRNAYGETLVELGKEYPNLVVLDSDLSGSTKTAMFAKQYPDRFFNAGIAEQNMIGMASGLSLTGKIVFAS
SFAMFASGRPWEQIRNSVAYANLNVKIAATHSGITVGEDGATHQMTEDIAIMRAIPNMIVIAPSDYYEAKSVIRWSATYD
GPVYIRMPRGDTETIFKDEEDAKFAFGKAKIIKDGKDLTIIATGEIIPEAIKASEILKEKGIDAEVIIMATIKPIDEQAV
INSNDFVVSVEDHNIIGGLGGAISEVIASNGLNKKLLRIGINDEFGESGKANELLKYYKLDSESIAKKIIEEFK

Sequences:

>Translated_314_residues
MDYKIGDKKAMRNAYGETLVELGKEYPNLVVLDSDLSGSTKTAMFAKQYPDRFFNAGIAEQNMIGMASGLSLTGKIVFAS
SFAMFASGRPWEQIRNSVAYANLNVKIAATHSGITVGEDGATHQMTEDIAIMRAIPNMIVIAPSDYYEAKSVIRWSATYD
GPVYIRMPRGDTETIFKDEEDAKFAFGKAKIIKDGKDLTIIATGEIIPEAIKASEILKEKGIDAEVIIMATIKPIDEQAV
INSNDFVVSVEDHNIIGGLGGAISEVIASNGLNKKLLRIGINDEFGESGKANELLKYYKLDSESIAKKIIEEFK
>Mature_314_residues
MDYKIGDKKAMRNAYGETLVELGKEYPNLVVLDSDLSGSTKTAMFAKQYPDRFFNAGIAEQNMIGMASGLSLTGKIVFAS
SFAMFASGRPWEQIRNSVAYANLNVKIAATHSGITVGEDGATHQMTEDIAIMRAIPNMIVIAPSDYYEAKSVIRWSATYD
GPVYIRMPRGDTETIFKDEEDAKFAFGKAKIIKDGKDLTIIATGEIIPEAIKASEILKEKGIDAEVIIMATIKPIDEQAV
INSNDFVVSVEDHNIIGGLGGAISEVIASNGLNKKLLRIGINDEFGESGKANELLKYYKLDSESIAKKIIEEFK

Specific function: Catalyzes The Acyloin Condensation Reaction Between C Atoms 2 And 3 Of Pyruvate And Glyceraldehyde 3-Phosphate To Yield 1-Deoxy-D-Xylulose-5-Phosphate (Dxp). [C]

COG id: COG3958

COG function: function code G; Transketolase, C-terminal subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=315, Percent_Identity=35.5555555555556, Blast_Score=195, Evalue=4e-50,
Organism=Homo sapiens, GI4507521, Length=315, Percent_Identity=35.5555555555556, Blast_Score=195, Evalue=4e-50,
Organism=Homo sapiens, GI225637461, Length=311, Percent_Identity=34.0836012861736, Blast_Score=173, Evalue=1e-43,
Organism=Homo sapiens, GI225637459, Length=311, Percent_Identity=34.0836012861736, Blast_Score=173, Evalue=2e-43,
Organism=Homo sapiens, GI225637463, Length=311, Percent_Identity=34.0836012861736, Blast_Score=173, Evalue=2e-43,
Organism=Homo sapiens, GI133778974, Length=312, Percent_Identity=32.6923076923077, Blast_Score=167, Evalue=8e-42,
Organism=Escherichia coli, GI1786622, Length=299, Percent_Identity=30.4347826086957, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI48994911, Length=251, Percent_Identity=30.2788844621514, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788808, Length=323, Percent_Identity=26.9349845201238, Blast_Score=81, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17539652, Length=318, Percent_Identity=34.9056603773585, Blast_Score=170, Evalue=1e-42,
Organism=Saccharomyces cerevisiae, GI6319593, Length=330, Percent_Identity=26.6666666666667, Blast_Score=79, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6325331, Length=333, Percent_Identity=25.5255255255255, Blast_Score=77, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24666278, Length=315, Percent_Identity=32.0634920634921, Blast_Score=152, Evalue=3e-37,
Organism=Drosophila melanogaster, GI24645119, Length=273, Percent_Identity=34.4322344322344, Blast_Score=151, Evalue=5e-37,
Organism=Drosophila melanogaster, GI45551847, Length=273, Percent_Identity=34.4322344322344, Blast_Score=151, Evalue=5e-37,
Organism=Drosophila melanogaster, GI45550715, Length=273, Percent_Identity=34.4322344322344, Blast_Score=151, Evalue=5e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR020826
- InterPro:   IPR005476 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 34312; Mature: 34312

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYKIGDKKAMRNAYGETLVELGKEYPNLVVLDSDLSGSTKTAMFAKQYPDRFFNAGIAE
CCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHCCHHHHHCCCCC
QNMIGMASGLSLTGKIVFASSFAMFASGRPWEQIRNSVAYANLNVKIAATHSGITVGEDG
CCHHEEECCCCEEEEEEEEEEEHHHCCCCCHHHHHCCEEEEEEEEEEEEECCCEEECCCC
ATHQMTEDIAIMRAIPNMIVIAPSDYYEAKSVIRWSATYDGPVYIRMPRGDTETIFKDEE
CCHHHHHHHHHHHHCCCEEEECCCCHHHCHHEEEEEEECCCEEEEEECCCCCCCEECCCC
DAKFAFGKAKIIKDGKDLTIIATGEIIPEAIKASEILKEKGIDAEVIIMATIKPIDEQAV
CCEEEECEEEEEECCCCEEEEEECCCCHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCEE
INSNDFVVSVEDHNIIGGLGGAISEVIASNGLNKKLLRIGINDEFGESGKANELLKYYKL
ECCCCEEEEEECCCEECCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHCC
DSESIAKKIIEEFK
CHHHHHHHHHHHCC
>Mature Secondary Structure
MDYKIGDKKAMRNAYGETLVELGKEYPNLVVLDSDLSGSTKTAMFAKQYPDRFFNAGIAE
CCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHCCHHHHHCCCCC
QNMIGMASGLSLTGKIVFASSFAMFASGRPWEQIRNSVAYANLNVKIAATHSGITVGEDG
CCHHEEECCCCEEEEEEEEEEEHHHCCCCCHHHHHCCEEEEEEEEEEEEECCCEEECCCC
ATHQMTEDIAIMRAIPNMIVIAPSDYYEAKSVIRWSATYDGPVYIRMPRGDTETIFKDEE
CCHHHHHHHHHHHHCCCEEEECCCCHHHCHHEEEEEEECCCEEEEEECCCCCCCEECCCC
DAKFAFGKAKIIKDGKDLTIIATGEIIPEAIKASEILKEKGIDAEVIIMATIKPIDEQAV
CCEEEECEEEEEECCCCEEEEEECCCCHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCEE
INSNDFVVSVEDHNIIGGLGGAISEVIASNGLNKKLLRIGINDEFGESGKANELLKYYKL
ECCCCEEEEEECCCEECCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHCC
DSESIAKKIIEEFK
CHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]