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The map label for this gene is mvp [H]

Identifier: 150401921

GI number: 150401921

Start: 1561150

End: 1561842

Strand: Direct

Name: mvp [H]

Synonym: Maeo_1499

Alternate gene names: 150401921

Gene position: 1561150-1561842 (Clockwise)

Preceding gene: 150401920

Following gene: 150401923

Centisome position: 99.47

GC content: 28.72

Gene sequence:

>693_bases
ATGAACAGGGAGCTCCATAAAAAAATATATTCTCCAAGAATATATAGAAAAATTGAATTTATAGTATTATTATGCACTTT
GGAAATTATTATTTCTTTTGTAATATCCACATATAATCCTCCGTATGAAGCATTATTATTTAAATTAGATTTTTTTTCCA
TCTCATTTTTAACTTTTGAGTTTATATATAGGTTTGTTGGGTCAAAAAATAAAACAAAGTTTTTTAAAGATAAATATAAT
CTTATAGATGCTTTTGTTATTGTGGCTTTTATAATGTATTTATTGGAGGCAACTTTAACCCATGTAATTGTCAGTCTTAG
AATAATTAATGCCGTTAGGGTATTAATGGTATTGAGGGCAATAAAATTTAAGGAGCTCCGGCTTAGCAATGAAACCATTA
ATTTCATTACAATATTTACATTTAGTTTTATACTATCCTGCTTTATCTGGTTGGTAGAACATGAAGTAAATCCAGGCATA
AATAATTTTGGGGATGCCTTTTATTTTACGGTGGTATCTTTAACTACAATAGGATACGGGGATATAACACCTATGACATC
AGAGGGAAAGCTTATAATAGTTTTAGCTGTGCTTTATGTAATATCCGGATTGGTCTCTAAGGCAAAAGGGTTTTTGCATG
AGGAACATCGGCTATATTATGAAAATAAAAAGATAAAAAAGAAAATCAGCTAA

Upstream 100 bases:

>100_bases
GAGATCGTAAAAATCGCTTTGCGATTTTGAGATAGTTTAATGAAAAAGACCGAAGATTAACTATAATATTTTTTACATTT
TATTTATATATGGCGATATT

Downstream 100 bases:

>100_bases
TAAAAATTAATTAAAAGTGGCATACAATATGAAAACGACCGAAGATTAGCTGTAAAAATTATTATCAAAAGTATAAAATT
ATTAAAATAAATATAAAATA

Product: Ion transport 2 domain-containing protein

Products: NA

Alternate protein names: MVP [H]

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MNRELHKKIYSPRIYRKIEFIVLLCTLEIIISFVISTYNPPYEALLFKLDFFSISFLTFEFIYRFVGSKNKTKFFKDKYN
LIDAFVIVAFIMYLLEATLTHVIVSLRIINAVRVLMVLRAIKFKELRLSNETINFITIFTFSFILSCFIWLVEHEVNPGI
NNFGDAFYFTVVSLTTIGYGDITPMTSEGKLIIVLAVLYVISGLVSKAKGFLHEEHRLYYENKKIKKKIS

Sequences:

>Translated_230_residues
MNRELHKKIYSPRIYRKIEFIVLLCTLEIIISFVISTYNPPYEALLFKLDFFSISFLTFEFIYRFVGSKNKTKFFKDKYN
LIDAFVIVAFIMYLLEATLTHVIVSLRIINAVRVLMVLRAIKFKELRLSNETINFITIFTFSFILSCFIWLVEHEVNPGI
NNFGDAFYFTVVSLTTIGYGDITPMTSEGKLIIVLAVLYVISGLVSKAKGFLHEEHRLYYENKKIKKKIS
>Mature_230_residues
MNRELHKKIYSPRIYRKIEFIVLLCTLEIIISFVISTYNPPYEALLFKLDFFSISFLTFEFIYRFVGSKNKTKFFKDKYN
LIDAFVIVAFIMYLLEATLTHVIVSLRIINAVRVLMVLRAIKFKELRLSNETINFITIFTFSFILSCFIWLVEHEVNPGI
NNFGDAFYFTVVSLTTIGYGDITPMTSEGKLIIVLAVLYVISGLVSKAKGFLHEEHRLYYENKKIKKKIS

Specific function: Voltage-gated potassium-selective channel opened by hyperpolarization [H]

COG id: COG1226

COG function: function code P; Kef-type K+ transport systems, predicted NAD-binding component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the potassium channel family [H]

Homologues:

Organism=Homo sapiens, GI45383011, Length=207, Percent_Identity=29.4685990338164, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI236462242, Length=253, Percent_Identity=25.6916996047431, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI236462079, Length=253, Percent_Identity=25.6916996047431, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI236461942, Length=253, Percent_Identity=25.6916996047431, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI236461719, Length=253, Percent_Identity=25.6916996047431, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI28373065, Length=253, Percent_Identity=25.6916996047431, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI4826784, Length=245, Percent_Identity=25.7142857142857, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI27436974, Length=200, Percent_Identity=25, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI26051262, Length=259, Percent_Identity=24.7104247104247, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI26051260, Length=259, Percent_Identity=24.7104247104247, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI26051266, Length=259, Percent_Identity=24.7104247104247, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI26051264, Length=259, Percent_Identity=24.7104247104247, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI27436993, Length=206, Percent_Identity=25.7281553398058, Blast_Score=64, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI25147238, Length=233, Percent_Identity=26.6094420600858, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI25147242, Length=233, Percent_Identity=26.6094420600858, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI72001311, Length=213, Percent_Identity=24.8826291079812, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI72001309, Length=213, Percent_Identity=24.8826291079812, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI72001307, Length=213, Percent_Identity=24.8826291079812, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71989381, Length=166, Percent_Identity=27.710843373494, Blast_Score=64, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI71989369, Length=166, Percent_Identity=27.710843373494, Blast_Score=64, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI71989361, Length=166, Percent_Identity=27.710843373494, Blast_Score=64, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI71989376, Length=166, Percent_Identity=27.710843373494, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI281363097, Length=235, Percent_Identity=24.6808510638298, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI281363095, Length=235, Percent_Identity=24.6808510638298, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI221330119, Length=235, Percent_Identity=24.6808510638298, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI281365536, Length=204, Percent_Identity=27.4509803921569, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI116007764, Length=204, Percent_Identity=27.4509803921569, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24656289, Length=204, Percent_Identity=27.4509803921569, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24656294, Length=204, Percent_Identity=27.4509803921569, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI221330117, Length=231, Percent_Identity=25.1082251082251, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013099
- InterPro:   IPR003091 [H]

Pfam domain/function: PF07885 Ion_trans_2 [H]

EC number: NA

Molecular weight: Translated: 26868; Mature: 26868

Theoretical pI: Translated: 9.84; Mature: 9.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRELHKKIYSPRIYRKIEFIVLLCTLEIIISFVISTYNPPYEALLFKLDFFSISFLTFE
CCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
FIYRFVGSKNKTKFFKDKYNLIDAFVIVAFIMYLLEATLTHVIVSLRIINAVRVLMVLRA
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IKFKELRLSNETINFITIFTFSFILSCFIWLVEHEVNPGINNFGDAFYFTVVSLTTIGYG
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCC
DITPMTSEGKLIIVLAVLYVISGLVSKAKGFLHEEHRLYYENKKIKKKIS
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNRELHKKIYSPRIYRKIEFIVLLCTLEIIISFVISTYNPPYEALLFKLDFFSISFLTFE
CCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
FIYRFVGSKNKTKFFKDKYNLIDAFVIVAFIMYLLEATLTHVIVSLRIINAVRVLMVLRA
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IKFKELRLSNETINFITIFTFSFILSCFIWLVEHEVNPGINNFGDAFYFTVVSLTTIGYG
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCC
DITPMTSEGKLIIVLAVLYVISGLVSKAKGFLHEEHRLYYENKKIKKKIS
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12640457; 8688087 [H]