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The map label for this gene is eif2b

Identifier: 150401923

GI number: 150401923

Start: 1563000

End: 1563419

Strand: Direct

Name: eif2b

Synonym: Maeo_1501

Alternate gene names: 150401923

Gene position: 1563000-1563419 (Clockwise)

Preceding gene: 150401921

Following gene: 150401924

Centisome position: 99.59

GC content: 31.9

Gene sequence:

>420_bases
ATGAATAGTGATTATTATGATTATGACGCACTTTTAAAAAGGGCTGTTAGTCAGCTTCCAGAAGAAGTGTTTAAAGATGT
TAGGTTTGAAGTTCCTCATGCAGATAGCTTCGTAGAAGGAAATAGAACTATGGTAAAGAACTTTGTAGATATTTCTAAGG
TTATACGAAGAGAACCGCAATTTTTTGCAAAATATGTATTGAAGGAGCTCGGAACTGCGGGAGATGTTGAAGGTCCAAGA
TTGATATTACAGGGTAAATTTGGAAATTACATTATCAATTCAAAAATTAAGAAATTTGTAGATGAATATGTATTATGTCC
AGAATGTGGAAAACCAGATACTAAAATAATTAAAGAAGGAAGAATTCACTTCCTTAAATGTATGGCTTGTGGTGCAATGA
AGCCTATTAAATTAATTTAA

Upstream 100 bases:

>100_bases
ATTATATATTAAAATTATTATGTTATTTTGGCATTATTTTTAGGATATAATTTTTTCTATTAAAAAAATTTATAGATATA
TTTATTTGGATGGTGAAAAT

Downstream 100 bases:

>100_bases
TATTATAGTATTATATTACTATTTTTTTATTTTTTTAGTTTCATGAATTGTTAATTGTAATACTAAATTTGGCGTTCTAA
ACAACTATAAATACCCATAT

Product: translation initiation factor IF-2 subunit beta

Products: NA

Alternate protein names: aIF2-beta; eIF-2-beta

Number of amino acids: Translated: 139; Mature: 139

Protein sequence:

>139_residues
MNSDYYDYDALLKRAVSQLPEEVFKDVRFEVPHADSFVEGNRTMVKNFVDISKVIRREPQFFAKYVLKELGTAGDVEGPR
LILQGKFGNYIINSKIKKFVDEYVLCPECGKPDTKIIKEGRIHFLKCMACGAMKPIKLI

Sequences:

>Translated_139_residues
MNSDYYDYDALLKRAVSQLPEEVFKDVRFEVPHADSFVEGNRTMVKNFVDISKVIRREPQFFAKYVLKELGTAGDVEGPR
LILQGKFGNYIINSKIKKFVDEYVLCPECGKPDTKIIKEGRIHFLKCMACGAMKPIKLI
>Mature_139_residues
MNSDYYDYDALLKRAVSQLPEEVFKDVRFEVPHADSFVEGNRTMVKNFVDISKVIRREPQFFAKYVLKELGTAGDVEGPR
LILQGKFGNYIINSKIKKFVDEYVLCPECGKPDTKIIKEGRIHFLKCMACGAMKPIKLI

Specific function: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA

COG id: COG1601

COG function: function code J; Translation initiation factor 2, beta subunit (eIF-2beta)/eIF-5 N-terminal domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the eIF-2-beta/eIF-5 family

Homologues:

Organism=Homo sapiens, GI29826335, Length=92, Percent_Identity=35.8695652173913, Blast_Score=79, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17508049, Length=111, Percent_Identity=32.4324324324324, Blast_Score=78, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6325018, Length=115, Percent_Identity=30.4347826086957, Blast_Score=77, Evalue=1e-15,
Organism=Drosophila melanogaster, GI17647377, Length=140, Percent_Identity=32.8571428571429, Blast_Score=79, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IF2B_META3 (A6UX55)

Other databases:

- EMBL:   CP000743
- RefSeq:   YP_001325689.1
- ProteinModelPortal:   A6UX55
- SMR:   A6UX55
- STRING:   A6UX55
- GeneID:   5327541
- GenomeReviews:   CP000743_GR
- KEGG:   mae:Maeo_1501
- eggNOG:   arNOG13033
- HOGENOM:   HBG738095
- OMA:   FLKCEAC
- ProtClustDB:   PRK03988
- BioCyc:   MAEO419665:MAEO_1501-MONOMER
- HAMAP:   MF_00232
- InterPro:   IPR004458
- InterPro:   IPR002735
- InterPro:   IPR016189
- InterPro:   IPR016190
- TIGRFAMs:   TIGR00311

Pfam domain/function: PF01873 eIF-5_eIF-2B; SSF100966 Transl_init_fac_IF2/IF5_N; SSF75689 Transl_init_fac_IF2/IF5_Zn-bd

EC number: NA

Molecular weight: Translated: 15955; Mature: 15955

Theoretical pI: Translated: 8.88; Mature: 8.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSDYYDYDALLKRAVSQLPEEVFKDVRFEVPHADSFVEGNRTMVKNFVDISKVIRREPQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCHHHHHHHHHHHHHHHCCHH
FFAKYVLKELGTAGDVEGPRLILQGKFGNYIINSKIKKFVDEYVLCPECGKPDTKIIKEG
HHHHHHHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
RIHFLKCMACGAMKPIKLI
HHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MNSDYYDYDALLKRAVSQLPEEVFKDVRFEVPHADSFVEGNRTMVKNFVDISKVIRREPQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCHHHHHHHHHHHHHHHCCHH
FFAKYVLKELGTAGDVEGPRLILQGKFGNYIINSKIKKFVDEYVLCPECGKPDTKIIKEG
HHHHHHHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
RIHFLKCMACGAMKPIKLI
HHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA