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The map label for this gene is trpS [H]

Identifier: 150401907

GI number: 150401907

Start: 1546536

End: 1547621

Strand: Reverse

Name: trpS [H]

Synonym: Maeo_1485

Alternate gene names: 150401907

Gene position: 1547621-1546536 (Counterclockwise)

Preceding gene: 150401908

Following gene: 150401906

Centisome position: 98.61

GC content: 30.39

Gene sequence:

>1086_bases
TTGATAACGCCATGGGAAGTTTCAGAAGATATAGATTATAAAAAAACAATGGAACAATTTGGAATAAAATCTATAAAAGA
GTTATTAGATGATATTGAAAATCCCCATCATTTTATGAGGAGAGGAATAATATTCGGACATAGAGATTTTGGAAGAATAA
TCAATTCAATAAATGAAAATAAAAAATTTGCCGTAGTTAGCGGAATGATGCCATCTGGTAAAATGCACTTTGGACATAAA
ATGATTATTGACCAACTGCTATATTATCAAAAGCATAATGCAGAAATATATATTCCAATAGCAGATTTGGAGGCATATTG
GGCAAGAGGCATGGATTTTGAAACCACAAAAAATCTTGCAATTGAGGAATATATAACTAACTACATAGCATTGGGTTTAA
ACCCCGATAAAATAAATATATATCTCCAATCAAAAAATGAATCAGTTAAAGATTTAGCTATGAAATTATCTAAAAGAGTT
AATTTTAGCGAAATGAAAGGAATATATGGTTTTGGTGGTGAAACTAACATTGGACATATATTTGCCCCAATTGTTCAAGT
TGCAGATATATTATACCCCCAATTAAATGAAAAAATACCAACAATAGTTCCCGTTGGAATTGACCAAGACCCCCATTTGA
GATTAACAAGAGATATAGCAAGTAGGGCAAATAAAACAAAAGAATTTAATTTTATGCCTCCATCTTCCACATATCATAGA
TTTATGACTGGACTATCTGGTGGAAAAATGAGTTCTTCAAAACCTGAAACTGCCATATTTCTAAGCGATACTCCATCTAA
ATCATTAAAAAAGAAAATTATGTCCAGTAAAACTGGAGGTAGAGAGACATTAGAGGAACAGAAAAAATTAGGAGGAACTC
CTGAAAATTGTGTAGTATATGAATTATTTGTATATCATTTAATTGATGATGATAAAGAGTTAAAAGAAATATATGATAGT
TGCAAAGGCGGGGAGCTCCTTTGTGGAAGTTGTAAAAAGAATTGTTATGAAAAAATTAAAGAATTTTTAACTGATTTAGG
AGAAAAAAGAGAATGTGCAAAAGAAATTGCCATGCAGATTGTATAA

Upstream 100 bases:

>100_bases
TATGTAAAAATGCACTTTTTAAAATAGAAAGGACAGTTATTGAAGATAAATTATAAATTAACAATTAATTATTATAACAA
TATGATATAACGGTGAAATT

Downstream 100 bases:

>100_bases
ATTGATTACCTTATAATATTATTATATACCATACAGGGAGCTCCGGGCACATACCTAATGATATATTCTATTATTCTATT
TTTTTAGCATACATTTATAT

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 361; Mature: 361

Protein sequence:

>361_residues
MITPWEVSEDIDYKKTMEQFGIKSIKELLDDIENPHHFMRRGIIFGHRDFGRIINSINENKKFAVVSGMMPSGKMHFGHK
MIIDQLLYYQKHNAEIYIPIADLEAYWARGMDFETTKNLAIEEYITNYIALGLNPDKINIYLQSKNESVKDLAMKLSKRV
NFSEMKGIYGFGGETNIGHIFAPIVQVADILYPQLNEKIPTIVPVGIDQDPHLRLTRDIASRANKTKEFNFMPPSSTYHR
FMTGLSGGKMSSSKPETAIFLSDTPSKSLKKKIMSSKTGGRETLEEQKKLGGTPENCVVYELFVYHLIDDDKELKEIYDS
CKGGELLCGSCKKNCYEKIKEFLTDLGEKRECAKEIAMQIV

Sequences:

>Translated_361_residues
MITPWEVSEDIDYKKTMEQFGIKSIKELLDDIENPHHFMRRGIIFGHRDFGRIINSINENKKFAVVSGMMPSGKMHFGHK
MIIDQLLYYQKHNAEIYIPIADLEAYWARGMDFETTKNLAIEEYITNYIALGLNPDKINIYLQSKNESVKDLAMKLSKRV
NFSEMKGIYGFGGETNIGHIFAPIVQVADILYPQLNEKIPTIVPVGIDQDPHLRLTRDIASRANKTKEFNFMPPSSTYHR
FMTGLSGGKMSSSKPETAIFLSDTPSKSLKKKIMSSKTGGRETLEEQKKLGGTPENCVVYELFVYHLIDDDKELKEIYDS
CKGGELLCGSCKKNCYEKIKEFLTDLGEKRECAKEIAMQIV
>Mature_361_residues
MITPWEVSEDIDYKKTMEQFGIKSIKELLDDIENPHHFMRRGIIFGHRDFGRIINSINENKKFAVVSGMMPSGKMHFGHK
MIIDQLLYYQKHNAEIYIPIADLEAYWARGMDFETTKNLAIEEYITNYIALGLNPDKINIYLQSKNESVKDLAMKLSKRV
NFSEMKGIYGFGGETNIGHIFAPIVQVADILYPQLNEKIPTIVPVGIDQDPHLRLTRDIASRANKTKEFNFMPPSSTYHR
FMTGLSGGKMSSSKPETAIFLSDTPSKSLKKKIMSSKTGGRETLEEQKKLGGTPENCVVYELFVYHLIDDDKELKEIYDS
CKGGELLCGSCKKNCYEKIKEFLTDLGEKRECAKEIAMQIV

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI47419916, Length=389, Percent_Identity=32.6478149100257, Blast_Score=176, Evalue=2e-44,
Organism=Homo sapiens, GI47419914, Length=389, Percent_Identity=32.6478149100257, Blast_Score=176, Evalue=2e-44,
Organism=Homo sapiens, GI47419920, Length=389, Percent_Identity=32.6478149100257, Blast_Score=176, Evalue=3e-44,
Organism=Homo sapiens, GI47419918, Length=389, Percent_Identity=32.6478149100257, Blast_Score=176, Evalue=3e-44,
Organism=Escherichia coli, GI1789786, Length=236, Percent_Identity=32.2033898305085, Blast_Score=65, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI72001474, Length=373, Percent_Identity=31.0991957104558, Blast_Score=170, Evalue=1e-42,
Organism=Saccharomyces cerevisiae, GI6324475, Length=383, Percent_Identity=31.8537859007833, Blast_Score=185, Evalue=1e-47,
Organism=Saccharomyces cerevisiae, GI6320474, Length=256, Percent_Identity=27.734375, Blast_Score=70, Evalue=6e-13,
Organism=Drosophila melanogaster, GI17864462, Length=380, Percent_Identity=31.8421052631579, Blast_Score=168, Evalue=6e-42,
Organism=Drosophila melanogaster, GI24645295, Length=380, Percent_Identity=31.8421052631579, Blast_Score=168, Evalue=6e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306
- InterPro:   IPR020653 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 41182; Mature: 41182

Theoretical pI: Translated: 7.29; Mature: 7.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITPWEVSEDIDYKKTMEQFGIKSIKELLDDIENPHHFMRRGIIFGHRDFGRIINSINEN
CCCCCCCCCCCCHHHHHHHHCHHHHHHHHHHCCCHHHHHHHCCCCCCHHHHHHHHHHCCC
KKFAVVSGMMPSGKMHFGHKMIIDQLLYYQKHNAEIYIPIADLEAYWARGMDFETTKNLA
CCEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHCCCCCCHHHHHH
IEEYITNYIALGLNPDKINIYLQSKNESVKDLAMKLSKRVNFSEMKGIYGFGGETNIGHI
HHHHHHHHEEECCCCCEEEEEEECCCCHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCHHH
FAPIVQVADILYPQLNEKIPTIVPVGIDQDPHLRLTRDIASRANKTKEFNFMPPSSTYHR
HHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHH
FMTGLSGGKMSSSKPETAIFLSDTPSKSLKKKIMSSKTGGRETLEEQKKLGGTPENCVVY
HHHCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCHHHH
ELFVYHLIDDDKELKEIYDSCKGGELLCGSCKKNCYEKIKEFLTDLGEKRECAKEIAMQI
HHHHHHHHCCCHHHHHHHHHCCCCCEEECHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHC
V
C
>Mature Secondary Structure
MITPWEVSEDIDYKKTMEQFGIKSIKELLDDIENPHHFMRRGIIFGHRDFGRIINSINEN
CCCCCCCCCCCCHHHHHHHHCHHHHHHHHHHCCCHHHHHHHCCCCCCHHHHHHHHHHCCC
KKFAVVSGMMPSGKMHFGHKMIIDQLLYYQKHNAEIYIPIADLEAYWARGMDFETTKNLA
CCEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHCCCCCCHHHHHH
IEEYITNYIALGLNPDKINIYLQSKNESVKDLAMKLSKRVNFSEMKGIYGFGGETNIGHI
HHHHHHHHEEECCCCCEEEEEEECCCCHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCHHH
FAPIVQVADILYPQLNEKIPTIVPVGIDQDPHLRLTRDIASRANKTKEFNFMPPSSTYHR
HHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHH
FMTGLSGGKMSSSKPETAIFLSDTPSKSLKKKIMSSKTGGRETLEEQKKLGGTPENCVVY
HHHCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCHHHH
ELFVYHLIDDDKELKEIYDSCKGGELLCGSCKKNCYEKIKEFLTDLGEKRECAKEIAMQI
HHHHHHHHCCCHHHHHHHHHCCCCCEEECHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHC
V
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]