Click here to switch to the map view.

The map label for this gene is resE [H]

Identifier: 150401859

GI number: 150401859

Start: 1492291

End: 1494213

Strand: Direct

Name: resE [H]

Synonym: Maeo_1437

Alternate gene names: 150401859

Gene position: 1492291-1494213 (Clockwise)

Preceding gene: 150401858

Following gene: 150401861

Centisome position: 95.08

GC content: 31.83

Gene sequence:

>1923_bases
ATGGGGGAAATACCCAAAATAAGAAAATTTGGAACTAAATTAACGATTTATTCTATTATTGTCGCACTTATCCCCGTGGT
TATTCTTGGAGTGGTGTCCTCACATACTATTACACAAACCATGAATGAGCAGGCACAAGACAAAATAAACACCGACTTAT
ATGCTGCGGAAGAGTTTATGGGGCACAACCTTGATAAATTGTCTTCTATATGTGAATATACCGTCAATTCTCCCGATTTA
CTGGAGAACATGAAAAATAAGAATATTAAAAATTTAAAAAATATACTATTATTGACAAAAAAATCTAGTGATGCTGATTT
TGTTACTTTATTTGATAATACTGGAAATGTAGTATTGAGGTCAAATAACAATAACTATGGAGATAAAGAACTTTCAGACC
ATATAAAAAAGGTTTTAAATGGGAGTAATGTCACAGCCACCATAATATTGGATGAAAATACTGTTAAAAAAGAGAATCTT
GAAAATAAAACAATTATTTATATATTTGATAAGGGTGATTTTGTACCTCTTGATATGGAGAATAAATCCATTGAATATAG
GGGTCTTGCACTGGTATCGATAAAACCAATATATGATAACAATACTGGCGAAATAATGGGGGCCCTGATGATATCAAAAG
TGCTCAATAAAGATACATATATTGTAGATAAAATTAAAGCAACTACAAAGGACACCTCCACCATATTTTTAGGAGGGCTT
AGAATATCTACAAATGTTCAAGAAAATCACGAACGGGCAATAGGGACCTTTGTATCGCAGAATGTATATGAACAAGTAAT
AAAAAAAGGAGAAATATACTATGGGCGTGCATTTGTTGTTGATGATTGGTATTTAACAGCATACAAACCAATTAAAGATG
ATAACAATAATATTATCGGAATGATATATGTTGGAGTTCCAGAAAAGCCCTTTATCGCACTCCAAGATAAAATAAAACAC
ATAATTTTATGGGTTGGTTTAGTAGCCTTTTTAATGGCCTTGGTGGTTTCGGTAATTATTAACAGCACCATTACAAGACC
AATAAAGAAGCTGAAAAAAGGAGTAGAAATGATGGGAAAGGGGGACTATAATTTCAGAGTTAATATTAATAGCAATGATG
AATTTGAAGAACTTGCACATGCATTCAACAAAATGGCCGATGAAATTAAAAGCTCACAAGAAAAATTAAAAAAACAAGCC
GAAAAGCTGGAAATATCATACAATGAACTGAAAAAACTGGATAAATTCAAATCCGAAATAATATCCATAGTTTCGCATGA
GTTAAGAACGCCACTGACCTCAATAAAAGGGTATGTAGAGCTTGTATTAGATGGCACAATGGGCACCATAAACGAATCTC
AAAAAAGATGTCTTGAAATTGCCAATGAAAATATTGACCGGTTAAAAAGGTTGATAGATAATATGCTTGATTTATCAAAA
ATAGAGCGTGGAGAGCTAAAAATGGACATATCCAAGGTGAATTTAAATGATATCGTTCAAAATGTGGTTCATTCATTAAA
GCCATTGGCTGATGGAAAGAATATAAAAATAATAAATAAAGTAGAGCCCATAACTGCAAATTTGGATAAAGATAAAATAA
CAGGTGTGCTAACTAATTTAATAGAGAATGCCATAAAATTCTCCCCCGTAAACGAAAATGTAACTATTGAGGCATTTAAA
GAAAATAATATGGTACATATAACTGTAAAAGATAACGGTCCAGGTATACCAAAATCTGAATTAACTAAAATATTTGATAT
ATTCTATCAAGTTAATTCTTCTGCAAAAAGAATAAAAAGTGGTTCGGGTCTTGGTTTAGCGATATGTAAAAGTATCGTGG
AATCCCATGGTGGAAAAATATGGGTAGAAAGTAAGTTTGGAAAAGAAAGTACATTCCATATATTGCTCCCATTGGATAAA
TAA

Upstream 100 bases:

>100_bases
AGTAAATGAGTTAATATTAAAAATGCAAAAGGGCAATAAATAGGATAAATAAATAGGATATTTAGGTAGATTACTAAATT
AATAATATATAGGTGTAAAT

Downstream 100 bases:

>100_bases
TGCTGGTTAAGAATTTTATCTTAATGCCGATGGCGAATATAGTTAATCTTAAAAACTATCTCTTTATTGTCCAAAATAAT
TAAATAAAATCTCTTCGAGA

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 640; Mature: 639

Protein sequence:

>640_residues
MGEIPKIRKFGTKLTIYSIIVALIPVVILGVVSSHTITQTMNEQAQDKINTDLYAAEEFMGHNLDKLSSICEYTVNSPDL
LENMKNKNIKNLKNILLLTKKSSDADFVTLFDNTGNVVLRSNNNNYGDKELSDHIKKVLNGSNVTATIILDENTVKKENL
ENKTIIYIFDKGDFVPLDMENKSIEYRGLALVSIKPIYDNNTGEIMGALMISKVLNKDTYIVDKIKATTKDTSTIFLGGL
RISTNVQENHERAIGTFVSQNVYEQVIKKGEIYYGRAFVVDDWYLTAYKPIKDDNNNIIGMIYVGVPEKPFIALQDKIKH
IILWVGLVAFLMALVVSVIINSTITRPIKKLKKGVEMMGKGDYNFRVNINSNDEFEELAHAFNKMADEIKSSQEKLKKQA
EKLEISYNELKKLDKFKSEIISIVSHELRTPLTSIKGYVELVLDGTMGTINESQKRCLEIANENIDRLKRLIDNMLDLSK
IERGELKMDISKVNLNDIVQNVVHSLKPLADGKNIKIINKVEPITANLDKDKITGVLTNLIENAIKFSPVNENVTIEAFK
ENNMVHITVKDNGPGIPKSELTKIFDIFYQVNSSAKRIKSGSGLGLAICKSIVESHGGKIWVESKFGKESTFHILLPLDK

Sequences:

>Translated_640_residues
MGEIPKIRKFGTKLTIYSIIVALIPVVILGVVSSHTITQTMNEQAQDKINTDLYAAEEFMGHNLDKLSSICEYTVNSPDL
LENMKNKNIKNLKNILLLTKKSSDADFVTLFDNTGNVVLRSNNNNYGDKELSDHIKKVLNGSNVTATIILDENTVKKENL
ENKTIIYIFDKGDFVPLDMENKSIEYRGLALVSIKPIYDNNTGEIMGALMISKVLNKDTYIVDKIKATTKDTSTIFLGGL
RISTNVQENHERAIGTFVSQNVYEQVIKKGEIYYGRAFVVDDWYLTAYKPIKDDNNNIIGMIYVGVPEKPFIALQDKIKH
IILWVGLVAFLMALVVSVIINSTITRPIKKLKKGVEMMGKGDYNFRVNINSNDEFEELAHAFNKMADEIKSSQEKLKKQA
EKLEISYNELKKLDKFKSEIISIVSHELRTPLTSIKGYVELVLDGTMGTINESQKRCLEIANENIDRLKRLIDNMLDLSK
IERGELKMDISKVNLNDIVQNVVHSLKPLADGKNIKIINKVEPITANLDKDKITGVLTNLIENAIKFSPVNENVTIEAFK
ENNMVHITVKDNGPGIPKSELTKIFDIFYQVNSSAKRIKSGSGLGLAICKSIVESHGGKIWVESKFGKESTFHILLPLDK
>Mature_639_residues
GEIPKIRKFGTKLTIYSIIVALIPVVILGVVSSHTITQTMNEQAQDKINTDLYAAEEFMGHNLDKLSSICEYTVNSPDLL
ENMKNKNIKNLKNILLLTKKSSDADFVTLFDNTGNVVLRSNNNNYGDKELSDHIKKVLNGSNVTATIILDENTVKKENLE
NKTIIYIFDKGDFVPLDMENKSIEYRGLALVSIKPIYDNNTGEIMGALMISKVLNKDTYIVDKIKATTKDTSTIFLGGLR
ISTNVQENHERAIGTFVSQNVYEQVIKKGEIYYGRAFVVDDWYLTAYKPIKDDNNNIIGMIYVGVPEKPFIALQDKIKHI
ILWVGLVAFLMALVVSVIINSTITRPIKKLKKGVEMMGKGDYNFRVNINSNDEFEELAHAFNKMADEIKSSQEKLKKQAE
KLEISYNELKKLDKFKSEIISIVSHELRTPLTSIKGYVELVLDGTMGTINESQKRCLEIANENIDRLKRLIDNMLDLSKI
ERGELKMDISKVNLNDIVQNVVHSLKPLADGKNIKIINKVEPITANLDKDKITGVLTNLIENAIKFSPVNENVTIEAFKE
NNMVHITVKDNGPGIPKSELTKIFDIFYQVNSSAKRIKSGSGLGLAICKSIVESHGGKIWVESKFGKESTFHILLPLDK

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=296, Percent_Identity=28.3783783783784, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI145693157, Length=244, Percent_Identity=30.7377049180328, Blast_Score=123, Evalue=4e-29,
Organism=Escherichia coli, GI1789149, Length=404, Percent_Identity=25.990099009901, Blast_Score=123, Evalue=4e-29,
Organism=Escherichia coli, GI1788713, Length=244, Percent_Identity=32.7868852459016, Blast_Score=119, Evalue=5e-28,
Organism=Escherichia coli, GI1786912, Length=263, Percent_Identity=28.8973384030418, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1786600, Length=230, Percent_Identity=28.695652173913, Blast_Score=117, Evalue=3e-27,
Organism=Escherichia coli, GI48994928, Length=231, Percent_Identity=30.3030303030303, Blast_Score=117, Evalue=3e-27,
Organism=Escherichia coli, GI87082128, Length=320, Percent_Identity=26.25, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1786783, Length=328, Percent_Identity=24.6951219512195, Blast_Score=112, Evalue=1e-25,
Organism=Escherichia coli, GI1787894, Length=322, Percent_Identity=26.0869565217391, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1788279, Length=328, Percent_Identity=30.4878048780488, Blast_Score=105, Evalue=8e-24,
Organism=Escherichia coli, GI87081816, Length=342, Percent_Identity=24.5614035087719, Blast_Score=103, Evalue=5e-23,
Organism=Escherichia coli, GI1790436, Length=241, Percent_Identity=31.9502074688797, Blast_Score=101, Evalue=2e-22,
Organism=Escherichia coli, GI1788549, Length=255, Percent_Identity=28.2352941176471, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1790861, Length=335, Percent_Identity=22.3880597014925, Blast_Score=86, Evalue=1e-17,
Organism=Escherichia coli, GI1790346, Length=303, Percent_Identity=22.1122112211221, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1789403, Length=203, Percent_Identity=30.0492610837438, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1789808, Length=277, Percent_Identity=24.9097472924188, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI1790551, Length=303, Percent_Identity=22.4422442244224, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1790300, Length=251, Percent_Identity=25.8964143426295, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1787374, Length=281, Percent_Identity=25.6227758007117, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 71939; Mature: 71808

Theoretical pI: Translated: 8.58; Mature: 8.58

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGEIPKIRKFGTKLTIYSIIVALIPVVILGVVSSHTITQTMNEQAQDKINTDLYAAEEFM
CCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHH
GHNLDKLSSICEYTVNSPDLLENMKNKNIKNLKNILLLTKKSSDADFVTLFDNTGNVVLR
CCCHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHEEEEEECCCCCCEEEEEECCCCEEEE
SNNNNYGDKELSDHIKKVLNGSNVTATIILDENTVKKENLENKTIIYIFDKGDFVPLDME
CCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCEEEEEECCCCEEEECCC
NKSIEYRGLALVSIKPIYDNNTGEIMGALMISKVLNKDTYIVDKIKATTKDTSTIFLGGL
CCCEEECCEEEEEEEEEEECCHHHHHHHHHHHHHHCCCCEEEEHHHCCCCCCCEEEEEEE
RISTNVQENHERAIGTFVSQNVYEQVIKKGEIYYGRAFVVDDWYLTAYKPIKDDNNNIIG
EEECCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECEEEEEECCCCCCCCCEEE
MIYVGVPEKPFIALQDKIKHIILWVGLVAFLMALVVSVIINSTITRPIKKLKKGVEMMGK
EEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GDYNFRVNINSNDEFEELAHAFNKMADEIKSSQEKLKKQAEKLEISYNELKKLDKFKSEI
CCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
ISIVSHELRTPLTSIKGYVELVLDGTMGTINESQKRCLEIANENIDRLKRLIDNMLDLSK
HHHHHHHHHCCHHHHHHEEEEEEECCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
IERGELKMDISKVNLNDIVQNVVHSLKPLADGKNIKIINKVEPITANLDKDKITGVLTNL
CCCCCEEEEEEECCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHH
IENAIKFSPVNENVTIEAFKENNMVHITVKDNGPGIPKSELTKIFDIFYQVNSSAKRIKS
HHHHHEECCCCCCEEEEEEECCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCHHHHHCC
GSGLGLAICKSIVESHGGKIWVESKFGKESTFHILLPLDK
CCCCHHHHHHHHHHHCCCEEEEEECCCCCCEEEEEEECCC
>Mature Secondary Structure 
GEIPKIRKFGTKLTIYSIIVALIPVVILGVVSSHTITQTMNEQAQDKINTDLYAAEEFM
CCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHH
GHNLDKLSSICEYTVNSPDLLENMKNKNIKNLKNILLLTKKSSDADFVTLFDNTGNVVLR
CCCHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHEEEEEECCCCCCEEEEEECCCCEEEE
SNNNNYGDKELSDHIKKVLNGSNVTATIILDENTVKKENLENKTIIYIFDKGDFVPLDME
CCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCEEEEEECCCCEEEECCC
NKSIEYRGLALVSIKPIYDNNTGEIMGALMISKVLNKDTYIVDKIKATTKDTSTIFLGGL
CCCEEECCEEEEEEEEEEECCHHHHHHHHHHHHHHCCCCEEEEHHHCCCCCCCEEEEEEE
RISTNVQENHERAIGTFVSQNVYEQVIKKGEIYYGRAFVVDDWYLTAYKPIKDDNNNIIG
EEECCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECEEEEEECCCCCCCCCEEE
MIYVGVPEKPFIALQDKIKHIILWVGLVAFLMALVVSVIINSTITRPIKKLKKGVEMMGK
EEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GDYNFRVNINSNDEFEELAHAFNKMADEIKSSQEKLKKQAEKLEISYNELKKLDKFKSEI
CCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
ISIVSHELRTPLTSIKGYVELVLDGTMGTINESQKRCLEIANENIDRLKRLIDNMLDLSK
HHHHHHHHHCCHHHHHHEEEEEEECCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
IERGELKMDISKVNLNDIVQNVVHSLKPLADGKNIKIINKVEPITANLDKDKITGVLTNL
CCCCCEEEEEEECCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHH
IENAIKFSPVNENVTIEAFKENNMVHITVKDNGPGIPKSELTKIFDIFYQVNSSAKRIKS
HHHHHEECCCCCCEEEEEEECCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCHHHHHCC
GSGLGLAICKSIVESHGGKIWVESKFGKESTFHILLPLDK
CCCCHHHHHHHHHHHCCCEEEEEECCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]