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The map label for this gene is yceE [C]

Identifier: 150401740

GI number: 150401740

Start: 1380765

End: 1381985

Strand: Reverse

Name: yceE [C]

Synonym: Maeo_1318

Alternate gene names: 150401740

Gene position: 1381985-1380765 (Counterclockwise)

Preceding gene: 150401741

Following gene: 150401739

Centisome position: 88.05

GC content: 31.94

Gene sequence:

>1221_bases
ATGGAAACGGTAATAATATTATGGATTACAACATTTATAACAATGTTAGGAATTGGGTTAATAGCTCCACTTATGTCTAT
TTATGCTAAAAGCTTAGGGGCGTCAAACTTAGACATAGGACTTATTTTTGGCTCTTTTGCAATAGCAAGAACCATAGCTC
AAATGCCTGTTGGGAGTTTATCGGACAAATATGGAAAAAAGATATTCATATTAATCGGAACATTTTTCTGCGGGATTTTT
ACGCTATCCTACGCCTTTGTAGCTTCTGTTATTGGATTAATATTTGTTAGAGTATTAAATGGTGTATTCTCCTCATTTAT
TACTCCTGTTGCCGGAGCCTATGTTGCGTCAATAGCTCCAAGGGAAAAACTTGGAGAATATATGGGATTATTCAGTAGTG
CAATAGCTCTTGGATTTGCCACAGGTCCATTAATTGGAGGATTTCTCGCAGAGTGGTATGGATTGACTACACCATTTTAT
TTTTGTGGAGCAATTACCTTTTTTGCCTTTATTGTTAGTTATTTTAAATTAAAAAATATAATGGTAAATGAAAATGGCGA
TTTTCAATATACTGATAAATTATTATTTTATAAACGGGACAATTTACAAAACTACAAACAAAAATTAATATCATTTGAAT
TTTTGAAAAATAAATATTTTTTAGCCTCTTATATTATGAATACAACATATATGGCAACCACAGCAGGAGTTGTGGGTTAT
TTGGCAATATATGCCCATGGCTTCAATATTGGATTGGGAGAAGTTGGATTTTTAATAGCCTCTACAAATTTAGTTATGGG
GATATTACAGAGAGCTTTTGGGAAGATATATGATAAAAAAGGCAATATATTAATAATTATTGGGCTAATAATTGCATCAG
TTGGGGTTTGGTCATTATCTGAAAGCTATTCCTTTTTAACCATGCTTGGAGCTCTTATGATAATGGCTGTTGGTAATGCA
ATATATACTCCTGCCATTAATGCACTATCTATGAAAGAAATATTGTCACATAAAAAAGGTAGTGCCATGGGATTTTTTAC
CACCAGTTTAAACATTGGTATGTTTATTGGTGCCGTAGTTCTTGGTTTTGTGGCTGATTATGTTGGTTTATCTAATATGT
ATAAATTTGCCGTGATATCTTCATTTATAATATGTTCCATGGCATATCTTGCAATAGTAAAAGAAGATAAAAAGAAAATA
GAAAGAAGAGATAGAAAATAA

Upstream 100 bases:

>100_bases
ATAAAAGATATGAAAATTAATATATATAACCATAAACATGCCATATAACATACCAAACAAAAACAAAAATGGAAATATAA
TGAATAAAAACACAAATCCA

Downstream 100 bases:

>100_bases
TATTAATATATATAATATCTATAATCTAAAAGAGAGTATATATTATGACAATAAAAAAAATGGAAGCAATTGTTAAAGGA
TTAATAAACGCAGGATATTT

Product: major facilitator transporter

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 406; Mature: 406

Protein sequence:

>406_residues
METVIILWITTFITMLGIGLIAPLMSIYAKSLGASNLDIGLIFGSFAIARTIAQMPVGSLSDKYGKKIFILIGTFFCGIF
TLSYAFVASVIGLIFVRVLNGVFSSFITPVAGAYVASIAPREKLGEYMGLFSSAIALGFATGPLIGGFLAEWYGLTTPFY
FCGAITFFAFIVSYFKLKNIMVNENGDFQYTDKLLFYKRDNLQNYKQKLISFEFLKNKYFLASYIMNTTYMATTAGVVGY
LAIYAHGFNIGLGEVGFLIASTNLVMGILQRAFGKIYDKKGNILIIIGLIIASVGVWSLSESYSFLTMLGALMIMAVGNA
IYTPAINALSMKEILSHKKGSAMGFFTTSLNIGMFIGAVVLGFVADYVGLSNMYKFAVISSFIICSMAYLAIVKEDKKKI
ERRDRK

Sequences:

>Translated_406_residues
METVIILWITTFITMLGIGLIAPLMSIYAKSLGASNLDIGLIFGSFAIARTIAQMPVGSLSDKYGKKIFILIGTFFCGIF
TLSYAFVASVIGLIFVRVLNGVFSSFITPVAGAYVASIAPREKLGEYMGLFSSAIALGFATGPLIGGFLAEWYGLTTPFY
FCGAITFFAFIVSYFKLKNIMVNENGDFQYTDKLLFYKRDNLQNYKQKLISFEFLKNKYFLASYIMNTTYMATTAGVVGY
LAIYAHGFNIGLGEVGFLIASTNLVMGILQRAFGKIYDKKGNILIIIGLIIASVGVWSLSESYSFLTMLGALMIMAVGNA
IYTPAINALSMKEILSHKKGSAMGFFTTSLNIGMFIGAVVLGFVADYVGLSNMYKFAVISSFIICSMAYLAIVKEDKKKI
ERRDRK
>Mature_406_residues
METVIILWITTFITMLGIGLIAPLMSIYAKSLGASNLDIGLIFGSFAIARTIAQMPVGSLSDKYGKKIFILIGTFFCGIF
TLSYAFVASVIGLIFVRVLNGVFSSFITPVAGAYVASIAPREKLGEYMGLFSSAIALGFATGPLIGGFLAEWYGLTTPFY
FCGAITFFAFIVSYFKLKNIMVNENGDFQYTDKLLFYKRDNLQNYKQKLISFEFLKNKYFLASYIMNTTYMATTAGVVGY
LAIYAHGFNIGLGEVGFLIASTNLVMGILQRAFGKIYDKKGNILIIIGLIIASVGVWSLSESYSFLTMLGALMIMAVGNA
IYTPAINALSMKEILSHKKGSAMGFFTTSLNIGMFIGAVVLGFVADYVGLSNMYKFAVISSFIICSMAYLAIVKEDKKKI
ERRDRK

Specific function: Unknown

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

Organism=Homo sapiens, GI217416366, Length=209, Percent_Identity=26.3157894736842, Blast_Score=73, Evalue=4e-13,
Organism=Escherichia coli, GI1787291, Length=303, Percent_Identity=25.4125412541254, Blast_Score=75, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR001958 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 44501; Mature: 44501

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METVIILWITTFITMLGIGLIAPLMSIYAKSLGASNLDIGLIFGSFAIARTIAQMPVGSL
CCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCC
SDKYGKKIFILIGTFFCGIFTLSYAFVASVIGLIFVRVLNGVFSSFITPVAGAYVASIAP
CHHHCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
REKLGEYMGLFSSAIALGFATGPLIGGFLAEWYGLTTPFYFCGAITFFAFIVSYFKLKNI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
MVNENGDFQYTDKLLFYKRDNLQNYKQKLISFEFLKNKYFLASYIMNTTYMATTAGVVGY
EECCCCCCEEECHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAIYAHGFNIGLGEVGFLIASTNLVMGILQRAFGKIYDKKGNILIIIGLIIASVGVWSLS
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHH
ESYSFLTMLGALMIMAVGNAIYTPAINALSMKEILSHKKGSAMGFFTTSLNIGMFIGAVV
HHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHH
LGFVADYVGLSNMYKFAVISSFIICSMAYLAIVKEDKKKIERRDRK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
METVIILWITTFITMLGIGLIAPLMSIYAKSLGASNLDIGLIFGSFAIARTIAQMPVGSL
CCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCC
SDKYGKKIFILIGTFFCGIFTLSYAFVASVIGLIFVRVLNGVFSSFITPVAGAYVASIAP
CHHHCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
REKLGEYMGLFSSAIALGFATGPLIGGFLAEWYGLTTPFYFCGAITFFAFIVSYFKLKNI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
MVNENGDFQYTDKLLFYKRDNLQNYKQKLISFEFLKNKYFLASYIMNTTYMATTAGVVGY
EECCCCCCEEECHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAIYAHGFNIGLGEVGFLIASTNLVMGILQRAFGKIYDKKGNILIIIGLIIASVGVWSLS
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHH
ESYSFLTMLGALMIMAVGNAIYTPAINALSMKEILSHKKGSAMGFFTTSLNIGMFIGAVV
HHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHH
LGFVADYVGLSNMYKFAVISSFIICSMAYLAIVKEDKKKIERRDRK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]