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The map label for this gene is 150401648

Identifier: 150401648

GI number: 150401648

Start: 1295377

End: 1297551

Strand: Reverse

Name: 150401648

Synonym: Maeo_1226

Alternate gene names: NA

Gene position: 1297551-1295377 (Counterclockwise)

Preceding gene: 150401649

Following gene: 150401647

Centisome position: 82.67

GC content: 32.83

Gene sequence:

>2175_bases
ATGAGTATATCAGAAGAAATACTTAAACTTATCGAAAATGGAATAACTGAATGGGACGAAATCTATACAAGATTAATCAA
CAATCACAAGAAAAATGCAGTATCTATGGCAAAAAATAGACTTATCCAACAAGGAAAAATAAAAGAAGAAACAATAAACG
GTAAAAAAATACTTTCAATACAACATGAGAATGAGGAACTAATATCTGATGTAGATGCATACCTATTCGAACATAGCCAA
GAAATAAAAGAATACTTTAAACTAATCCTACACCAGAACCCAGATAATAGAACCTTTAACATTAAAGAATTTATATTGTC
ATTCCCTCATTTAGCAGAATTAAGTGATATTATAAAAAACAATCCTTTTGAAGCAAGGAACATACTAACAAACATTTACA
AAGAAACATACGAAGAACTATTTGCAGAGGAAACGAACATAACACACATATTCATAACAAACCTCCTAACATCAAAAAAG
AAACTTTCAGAAATAGGAGCAAATGACATAGGAAAACTTGTAGAATTTGAATGTTCAATAGTTCAAGCATCAAAGAACAA
ATCAAGAACAACGGAAGCGGAATATCTGTGCTTTGAATGTGGAACTAAAAGAACTGTAAAACTTGACTTCTGGGAAGACC
CTGAAAAAAAGAAAGTATCCTGTCCAAACTGTTCAAATCAAAGAATGACAATTGACTCAAAAAGTAGGATAACATTCCAA
GAATTAATTGTCCAACAATTGGAAGTTTCACAAGATGGGAAACAACACACTGCATCATTATTCCTTGAAGATTCAGAACC
AATATATTCTGGAAAGTTAAGAGTAGTTGCAGTGCCAATTGAAAAATACAAAAAAGGAACATCTGTTGCAGATATACACT
TATACGCATTTGGATACGAAGAAATAGACAACATCGATATTAACATCACAGAAGATGACATTGAAAACATCTATAAAATA
GCAAAAGACCCAGAAGTTATAGAAAAATTAGCAAACTATATGCTCAGGGAAACAAAGGGAATGGATGAGGTAAAGAAAGC
CATATTTTTACAGCAAGTTAAAGGGGTAGAAAAAGGAGACAAAAGAAGGAATCTAAATATTCTTTTAATTACAGACCCAG
GAGTAGGAAAATCTACAATGATGCACCAACTTAAAAAACTTCCAAACACAAAGTATGCCACAATGTCAGGAGCATCAGGG
GCAGGATTAATTGGAGGTATAAATAAAGAAAAAACAGAGTTTGGGGAATCATGGGTAGTAAAACCGGGTATCTATGCCTT
AGCAGATGGGGGAACCGTATGTTTAGATGAATTTACACATAATAAAGAAGTAATGCCTTATGTCCATGATGCAATGGAAA
GCCAAATGGCAAAAATTACAAAGATGCAAAACAACCTTGAACTACCTGCAAGATGTGCAACATTGGCAGCATGTAATCCA
AAATTAGGAAGGTATGACTCAAACCTATCAGTTATGGAACAAGTCCCTATAAAACCCGAAACACTTTCAAGATTTGATTT
AATATTCCCATTAAGGGATGTTCCAGACAATGAAAACGATAAAGATATTTTAAAATTCATAATAAGAAGTGGAAATGAAA
AAATAAAAGGAACTGAAAAAAAGATAAAAATAAACGGCGTTGAACTTTCCGATGAACTGTTAATAAAGTATCTTCATTAT
GTTGATGAAAATTTCAAACCAACCATATCAGATGAAGCAGAAGAATTAATCATTGATTACTACTTAAAAATGAGGGAATT
ATCAAAAAATGGAGCCATAACAATTACAACAAGACAGGCTGAATCACTTATAAGATTATCCGAAGTGGTAGCCAAAGCCA
GGTTAAAGAATGAAGTTGATACCGAAGATGCAAGGGAAGCAATAGAACTTATGCAGTTCTGTTTAGAGCAAATATCTTAT
GACCCAGAAACTGGAAAAATAGATATTGATAAAGTTTATGGAATACCCAAGAGCAAAAGGGAAAAATCAGAACAGGTATT
AAAAATTATCGAAGATGAAAACAAATGCAAGGACATAGTAAGTGAAGAGATTATATTCGAACGGGCAGAAAAGGAATACA
ACATAACTATTGAGGAAGTAGAGCGTATTTTAGAAGTATTATCTATCCGAGGAGAGATATACAGCCCGAAATTTGGGTAT
TGGCGTACTACATAG

Upstream 100 bases:

>100_bases
ATAAAATAACACAATGCGATAAAATAGAGTATTTAATGGACACTGTAAGAGATAGAGAAAATATATCAAAAATATATTGA
TTAAGAAAAGAGGGGTAATT

Downstream 100 bases:

>100_bases
AGGTGAAAATATGATAAAAGAAGGCATGGGAAAAATAGCAATGGTAATAACAAAACATAATGGAGAATTTATAAGATATT
GTGATGAAATCACCAATATG

Product: MCM family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 724; Mature: 723

Protein sequence:

>724_residues
MSISEEILKLIENGITEWDEIYTRLINNHKKNAVSMAKNRLIQQGKIKEETINGKKILSIQHENEELISDVDAYLFEHSQ
EIKEYFKLILHQNPDNRTFNIKEFILSFPHLAELSDIIKNNPFEARNILTNIYKETYEELFAEETNITHIFITNLLTSKK
KLSEIGANDIGKLVEFECSIVQASKNKSRTTEAEYLCFECGTKRTVKLDFWEDPEKKKVSCPNCSNQRMTIDSKSRITFQ
ELIVQQLEVSQDGKQHTASLFLEDSEPIYSGKLRVVAVPIEKYKKGTSVADIHLYAFGYEEIDNIDINITEDDIENIYKI
AKDPEVIEKLANYMLRETKGMDEVKKAIFLQQVKGVEKGDKRRNLNILLITDPGVGKSTMMHQLKKLPNTKYATMSGASG
AGLIGGINKEKTEFGESWVVKPGIYALADGGTVCLDEFTHNKEVMPYVHDAMESQMAKITKMQNNLELPARCATLAACNP
KLGRYDSNLSVMEQVPIKPETLSRFDLIFPLRDVPDNENDKDILKFIIRSGNEKIKGTEKKIKINGVELSDELLIKYLHY
VDENFKPTISDEAEELIIDYYLKMRELSKNGAITITTRQAESLIRLSEVVAKARLKNEVDTEDAREAIELMQFCLEQISY
DPETGKIDIDKVYGIPKSKREKSEQVLKIIEDENKCKDIVSEEIIFERAEKEYNITIEEVERILEVLSIRGEIYSPKFGY
WRTT

Sequences:

>Translated_724_residues
MSISEEILKLIENGITEWDEIYTRLINNHKKNAVSMAKNRLIQQGKIKEETINGKKILSIQHENEELISDVDAYLFEHSQ
EIKEYFKLILHQNPDNRTFNIKEFILSFPHLAELSDIIKNNPFEARNILTNIYKETYEELFAEETNITHIFITNLLTSKK
KLSEIGANDIGKLVEFECSIVQASKNKSRTTEAEYLCFECGTKRTVKLDFWEDPEKKKVSCPNCSNQRMTIDSKSRITFQ
ELIVQQLEVSQDGKQHTASLFLEDSEPIYSGKLRVVAVPIEKYKKGTSVADIHLYAFGYEEIDNIDINITEDDIENIYKI
AKDPEVIEKLANYMLRETKGMDEVKKAIFLQQVKGVEKGDKRRNLNILLITDPGVGKSTMMHQLKKLPNTKYATMSGASG
AGLIGGINKEKTEFGESWVVKPGIYALADGGTVCLDEFTHNKEVMPYVHDAMESQMAKITKMQNNLELPARCATLAACNP
KLGRYDSNLSVMEQVPIKPETLSRFDLIFPLRDVPDNENDKDILKFIIRSGNEKIKGTEKKIKINGVELSDELLIKYLHY
VDENFKPTISDEAEELIIDYYLKMRELSKNGAITITTRQAESLIRLSEVVAKARLKNEVDTEDAREAIELMQFCLEQISY
DPETGKIDIDKVYGIPKSKREKSEQVLKIIEDENKCKDIVSEEIIFERAEKEYNITIEEVERILEVLSIRGEIYSPKFGY
WRTT
>Mature_723_residues
SISEEILKLIENGITEWDEIYTRLINNHKKNAVSMAKNRLIQQGKIKEETINGKKILSIQHENEELISDVDAYLFEHSQE
IKEYFKLILHQNPDNRTFNIKEFILSFPHLAELSDIIKNNPFEARNILTNIYKETYEELFAEETNITHIFITNLLTSKKK
LSEIGANDIGKLVEFECSIVQASKNKSRTTEAEYLCFECGTKRTVKLDFWEDPEKKKVSCPNCSNQRMTIDSKSRITFQE
LIVQQLEVSQDGKQHTASLFLEDSEPIYSGKLRVVAVPIEKYKKGTSVADIHLYAFGYEEIDNIDINITEDDIENIYKIA
KDPEVIEKLANYMLRETKGMDEVKKAIFLQQVKGVEKGDKRRNLNILLITDPGVGKSTMMHQLKKLPNTKYATMSGASGA
GLIGGINKEKTEFGESWVVKPGIYALADGGTVCLDEFTHNKEVMPYVHDAMESQMAKITKMQNNLELPARCATLAACNPK
LGRYDSNLSVMEQVPIKPETLSRFDLIFPLRDVPDNENDKDILKFIIRSGNEKIKGTEKKIKINGVELSDELLIKYLHYV
DENFKPTISDEAEELIIDYYLKMRELSKNGAITITTRQAESLIRLSEVVAKARLKNEVDTEDAREAIELMQFCLEQISYD
PETGKIDIDKVYGIPKSKREKSEQVLKIIEDENKCKDIVSEEIIFERAEKEYNITIEEVERILEVLSIRGEIYSPKFGYW
RTT

Specific function: Unknown

COG id: COG1241

COG function: function code L; Predicted ATPase involved in replication control, Cdc46/Mcm family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MCM domain [H]

Homologues:

Organism=Homo sapiens, GI33469919, Length=591, Percent_Identity=26.9035532994924, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI33469917, Length=591, Percent_Identity=26.9035532994924, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI33469968, Length=504, Percent_Identity=29.1666666666667, Blast_Score=157, Evalue=4e-38,
Organism=Homo sapiens, GI6631095, Length=381, Percent_Identity=30.9711286089239, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI33356547, Length=407, Percent_Identity=29.2383292383292, Blast_Score=152, Evalue=9e-37,
Organism=Homo sapiens, GI7427519, Length=569, Percent_Identity=24.6045694200351, Blast_Score=151, Evalue=3e-36,
Organism=Homo sapiens, GI33469922, Length=473, Percent_Identity=28.9640591966173, Blast_Score=144, Evalue=4e-34,
Organism=Homo sapiens, GI33469924, Length=608, Percent_Identity=24.0131578947368, Blast_Score=142, Evalue=2e-33,
Organism=Homo sapiens, GI19923727, Length=624, Percent_Identity=23.7179487179487, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI23510448, Length=380, Percent_Identity=28.4210526315789, Blast_Score=137, Evalue=4e-32,
Organism=Homo sapiens, GI310128402, Length=303, Percent_Identity=29.3729372937294, Blast_Score=107, Evalue=5e-23,
Organism=Homo sapiens, GI310115110, Length=303, Percent_Identity=29.3729372937294, Blast_Score=107, Evalue=5e-23,
Organism=Homo sapiens, GI310119838, Length=303, Percent_Identity=29.3729372937294, Blast_Score=107, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17508417, Length=588, Percent_Identity=28.2312925170068, Blast_Score=204, Evalue=1e-52,
Organism=Caenorhabditis elegans, GI17562702, Length=581, Percent_Identity=27.710843373494, Blast_Score=175, Evalue=9e-44,
Organism=Caenorhabditis elegans, GI71997752, Length=373, Percent_Identity=31.9034852546917, Blast_Score=167, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI17562700, Length=377, Percent_Identity=30.2387267904509, Blast_Score=159, Evalue=6e-39,
Organism=Caenorhabditis elegans, GI17554306, Length=355, Percent_Identity=29.8591549295775, Blast_Score=139, Evalue=5e-33,
Organism=Caenorhabditis elegans, GI71997571, Length=278, Percent_Identity=34.1726618705036, Blast_Score=137, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI71997563, Length=278, Percent_Identity=34.1726618705036, Blast_Score=137, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6325276, Length=594, Percent_Identity=28.4511784511784, Blast_Score=184, Evalue=4e-47,
Organism=Saccharomyces cerevisiae, GI6323304, Length=366, Percent_Identity=30.6010928961749, Blast_Score=153, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6319448, Length=622, Percent_Identity=25.08038585209, Blast_Score=151, Evalue=3e-37,
Organism=Saccharomyces cerevisiae, GI6321237, Length=347, Percent_Identity=29.971181556196, Blast_Score=144, Evalue=5e-35,
Organism=Saccharomyces cerevisiae, GI6319679, Length=285, Percent_Identity=28.7719298245614, Blast_Score=130, Evalue=8e-31,
Organism=Saccharomyces cerevisiae, GI6320803, Length=229, Percent_Identity=33.6244541484716, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI17137242, Length=558, Percent_Identity=27.7777777777778, Blast_Score=179, Evalue=4e-45,
Organism=Drosophila melanogaster, GI17137132, Length=577, Percent_Identity=26.6897746967071, Blast_Score=171, Evalue=1e-42,
Organism=Drosophila melanogaster, GI24645774, Length=576, Percent_Identity=28.2986111111111, Blast_Score=169, Evalue=7e-42,
Organism=Drosophila melanogaster, GI17530827, Length=545, Percent_Identity=25.6880733944954, Blast_Score=159, Evalue=5e-39,
Organism=Drosophila melanogaster, GI24639835, Length=380, Percent_Identity=32.3684210526316, Blast_Score=159, Evalue=9e-39,
Organism=Drosophila melanogaster, GI17647617, Length=325, Percent_Identity=30.1538461538462, Blast_Score=137, Evalue=3e-32,
Organism=Drosophila melanogaster, GI24647251, Length=242, Percent_Identity=24.3801652892562, Blast_Score=76, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR001208
- InterPro:   IPR018525
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00493 MCM [H]

EC number: NA

Molecular weight: Translated: 83077; Mature: 82946

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS50051 MCM_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSISEEILKLIENGITEWDEIYTRLINNHKKNAVSMAKNRLIQQGKIKEETINGKKILSI
CCHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHCCCCEEEEE
QHENEELISDVDAYLFEHSQEIKEYFKLILHQNPDNRTFNIKEFILSFPHLAELSDIIKN
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHCCCCHHHHHHHHCC
NPFEARNILTNIYKETYEELFAEETNITHIFITNLLTSKKKLSEIGANDIGKLVEFECSI
CCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHE
VQASKNKSRTTEAEYLCFECGTKRTVKLDFWEDPEKKKVSCPNCSNQRMTIDSKSRITFQ
EECCCCCCCCCHHHEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCEEEECCCCCHHHH
ELIVQQLEVSQDGKQHTASLFLEDSEPIYSGKLRVVAVPIEKYKKGTSVADIHLYAFGYE
HHHHHHHHHCCCCCHHHHEEEEECCCCCCCCCEEEEEEEHHHHCCCCCEEEEEEEEECCH
EIDNIDINITEDDIENIYKIAKDPEVIEKLANYMLRETKGMDEVKKAIFLQQVKGVEKGD
HHCCCEEEECHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCC
KRRNLNILLITDPGVGKSTMMHQLKKLPNTKYATMSGASGAGLIGGINKEKTEFGESWVV
CCCCCEEEEEECCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCHHHHCCCCEEE
KPGIYALADGGTVCLDEFTHNKEVMPYVHDAMESQMAKITKMQNNLELPARCATLAACNP
CCCEEEEECCCEEEEHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCC
KLGRYDSNLSVMEQVPIKPETLSRFDLIFPLRDVPDNENDKDILKFIIRSGNEKIKGTEK
CCCCCCCCCHHHHHCCCCCHHHHHHHEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCC
KIKINGVELSDELLIKYLHYVDENFKPTISDEAEELIIDYYLKMRELSKNGAITITTRQA
EEEEECCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEHHH
ESLIRLSEVVAKARLKNEVDTEDAREAIELMQFCLEQISYDPETGKIDIDKVYGIPKSKR
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHCCCCCHHH
EKSEQVLKIIEDENKCKDIVSEEIIFERAEKEYNITIEEVERILEVLSIRGEIYSPKFGY
HHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHCCCCCCCCCCC
WRTT
CCCC
>Mature Secondary Structure 
SISEEILKLIENGITEWDEIYTRLINNHKKNAVSMAKNRLIQQGKIKEETINGKKILSI
CHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHCCCCEEEEE
QHENEELISDVDAYLFEHSQEIKEYFKLILHQNPDNRTFNIKEFILSFPHLAELSDIIKN
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHCCCCHHHHHHHHCC
NPFEARNILTNIYKETYEELFAEETNITHIFITNLLTSKKKLSEIGANDIGKLVEFECSI
CCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHE
VQASKNKSRTTEAEYLCFECGTKRTVKLDFWEDPEKKKVSCPNCSNQRMTIDSKSRITFQ
EECCCCCCCCCHHHEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCEEEECCCCCHHHH
ELIVQQLEVSQDGKQHTASLFLEDSEPIYSGKLRVVAVPIEKYKKGTSVADIHLYAFGYE
HHHHHHHHHCCCCCHHHHEEEEECCCCCCCCCEEEEEEEHHHHCCCCCEEEEEEEEECCH
EIDNIDINITEDDIENIYKIAKDPEVIEKLANYMLRETKGMDEVKKAIFLQQVKGVEKGD
HHCCCEEEECHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCC
KRRNLNILLITDPGVGKSTMMHQLKKLPNTKYATMSGASGAGLIGGINKEKTEFGESWVV
CCCCCEEEEEECCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCHHHHCCCCEEE
KPGIYALADGGTVCLDEFTHNKEVMPYVHDAMESQMAKITKMQNNLELPARCATLAACNP
CCCEEEEECCCEEEEHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCC
KLGRYDSNLSVMEQVPIKPETLSRFDLIFPLRDVPDNENDKDILKFIIRSGNEKIKGTEK
CCCCCCCCCHHHHHCCCCCHHHHHHHEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCC
KIKINGVELSDELLIKYLHYVDENFKPTISDEAEELIIDYYLKMRELSKNGAITITTRQA
EEEEECCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEHHH
ESLIRLSEVVAKARLKNEVDTEDAREAIELMQFCLEQISYDPETGKIDIDKVYGIPKSKR
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHCCCCCHHH
EKSEQVLKIIEDENKCKDIVSEEIIFERAEKEYNITIEEVERILEVLSIRGEIYSPKFGY
HHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHCCCCCCCCCCC
WRTT
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]