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The map label for this gene is yfbQ [C]

Identifier: 150401408

GI number: 150401408

Start: 1006244

End: 1007545

Strand: Reverse

Name: yfbQ [C]

Synonym: Maeo_0984

Alternate gene names: 150401408

Gene position: 1007545-1006244 (Counterclockwise)

Preceding gene: 150401412

Following gene: 150401407

Centisome position: 64.2

GC content: 32.87

Gene sequence:

>1302_bases
ATGAGAACAGATATAACCCACGAAGGAGCAAATGAATTAACCTACGAAATAAGAGAAATCACAGAGGTTGCTAAAACGGT
GGAAAAACACGGAATAAATATTACCTGGGAGAATATTGGGGACCCAATAATAAAGGGGGAAAAAATTCCAGAATGGATGA
AAGAAATAATAGCAAATACATTAATGGATGATTATTCTTATGGATATTGCCCAACAAAAGGATTGTTGGAAACCAGGGAA
TTCATAGCCGATGAAACCAATAGAAAAAATGGGGCACAAATCACACCCGAGGATATTTTATTTTTTAATGGATTGGGTGA
AGCAATTACAAAAATATACGGACTTTTAAAAAAGGAATCCAGAGTAATAGGGCCATCTCCTGCATATCCTACCCACTCCT
CCGCAGAAGGGCTACATTCACGATGCCACCCACTTATGTATCGGATGGACGAAAATGACAACTGGAATCCCGATATAGAT
GATTTGACAAATAAAGTAAAATACAACCCCACAGTATCAGGAATATTAATTATAAACCCTGGAAATCCTACTGGTGCAGT
TTATTCAAAGAAAACCCTTGACGAAATAGTTGATTTGGCAAATGAATATGATTTATTTATATTATGTGATGAAATATACC
ATAATTTAGTTTATAATGGTAAAAAACATACGAATTTATCGGAAGTAATTGATGATGTTTGCGGAATATCTTTAAAAGGA
ATATCCAAAGAATTACCCTGGCCCGGGGCTCGATGTGGTTGGATGGAGACATATAACTACGATAAAGACCCATTATTTAA
AAGATATATTGACGGAATAGTTAAATTTAAGATGGTGGAGGTATGCTCCACTACGCTACCTCAAAAGGTAATACCCGAAA
TAATGGGAGCTCCTAAATTCAAACAATATTTAAAAGAGCGAAATAATTACTATGAAAAGGCGTCAAACTTTGCATATAAT
AAATTAAATAAAATTGATGGAATTACGATAAATAAAACTAATGGGGCATTTTATTCTACTGTGGTATTTGAGGAGGACAA
ATTAAATAACAGCCAAAGTTTAAAAATAGAAAATAAAGAATTACAAAAATACATTGAAAATGTTTCAAAAGGTCATAAAC
ACGATAGGAAGTTTGTTTATAATTTATTGGCATCCTCTGGTATTTGTGTGGTTCCTATGTCCTCATTTAACTCTGAATTA
AACGGATTTAGAACTACGCTTCTTGAAAGAGATGAAAATAAATTAAAATGGACTTATGAATCAATTGCTGAAAAAATAGA
GGAATATTTAAATAGCAATTAA

Upstream 100 bases:

>100_bases
AAATATATATTTATTCTATTATTATATTAATTATCAAATTTTATATTAATTATATTTTATTATTATTCTTATTATTTTAT
TAATTTTCACGAGAGGTACA

Downstream 100 bases:

>100_bases
ATATTAATTATTTTTATATCTTAGAATTATATTTTATATTTTTATTTTTTTATATTCTTTTATACTAATTTATATAAAAT
TTACAATAATGAATATACTT

Product: aminotransferase

Products: oxaloacetate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MRTDITHEGANELTYEIREITEVAKTVEKHGINITWENIGDPIIKGEKIPEWMKEIIANTLMDDYSYGYCPTKGLLETRE
FIADETNRKNGAQITPEDILFFNGLGEAITKIYGLLKKESRVIGPSPAYPTHSSAEGLHSRCHPLMYRMDENDNWNPDID
DLTNKVKYNPTVSGILIINPGNPTGAVYSKKTLDEIVDLANEYDLFILCDEIYHNLVYNGKKHTNLSEVIDDVCGISLKG
ISKELPWPGARCGWMETYNYDKDPLFKRYIDGIVKFKMVEVCSTTLPQKVIPEIMGAPKFKQYLKERNNYYEKASNFAYN
KLNKIDGITINKTNGAFYSTVVFEEDKLNNSQSLKIENKELQKYIENVSKGHKHDRKFVYNLLASSGICVVPMSSFNSEL
NGFRTTLLERDENKLKWTYESIAEKIEEYLNSN

Sequences:

>Translated_433_residues
MRTDITHEGANELTYEIREITEVAKTVEKHGINITWENIGDPIIKGEKIPEWMKEIIANTLMDDYSYGYCPTKGLLETRE
FIADETNRKNGAQITPEDILFFNGLGEAITKIYGLLKKESRVIGPSPAYPTHSSAEGLHSRCHPLMYRMDENDNWNPDID
DLTNKVKYNPTVSGILIINPGNPTGAVYSKKTLDEIVDLANEYDLFILCDEIYHNLVYNGKKHTNLSEVIDDVCGISLKG
ISKELPWPGARCGWMETYNYDKDPLFKRYIDGIVKFKMVEVCSTTLPQKVIPEIMGAPKFKQYLKERNNYYEKASNFAYN
KLNKIDGITINKTNGAFYSTVVFEEDKLNNSQSLKIENKELQKYIENVSKGHKHDRKFVYNLLASSGICVVPMSSFNSEL
NGFRTTLLERDENKLKWTYESIAEKIEEYLNSN
>Mature_433_residues
MRTDITHEGANELTYEIREITEVAKTVEKHGINITWENIGDPIIKGEKIPEWMKEIIANTLMDDYSYGYCPTKGLLETRE
FIADETNRKNGAQITPEDILFFNGLGEAITKIYGLLKKESRVIGPSPAYPTHSSAEGLHSRCHPLMYRMDENDNWNPDID
DLTNKVKYNPTVSGILIINPGNPTGAVYSKKTLDEIVDLANEYDLFILCDEIYHNLVYNGKKHTNLSEVIDDVCGISLKG
ISKELPWPGARCGWMETYNYDKDPLFKRYIDGIVKFKMVEVCSTTLPQKVIPEIMGAPKFKQYLKERNNYYEKASNFAYN
KLNKIDGITINKTNGAFYSTVVFEEDKLNNSQSLKIENKELQKYIENVSKGHKHDRKFVYNLLASSGICVVPMSSFNSEL
NGFRTTLLERDENKLKWTYESIAEKIEEYLNSN

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI19263340, Length=460, Percent_Identity=24.5652173913043, Blast_Score=105, Evalue=9e-23,
Organism=Homo sapiens, GI215599424, Length=388, Percent_Identity=26.8041237113402, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI4507369, Length=339, Percent_Identity=25.3687315634218, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI4885351, Length=454, Percent_Identity=23.7885462555066, Blast_Score=97, Evalue=2e-20,
Organism=Escherichia coli, GI1788627, Length=403, Percent_Identity=30.5210918114144, Blast_Score=168, Evalue=8e-43,
Organism=Caenorhabditis elegans, GI17567663, Length=432, Percent_Identity=25, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI71981209, Length=462, Percent_Identity=27.2727272727273, Blast_Score=115, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI71981215, Length=291, Percent_Identity=24.3986254295533, Blast_Score=73, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6320317, Length=374, Percent_Identity=28.6096256684492, Blast_Score=137, Evalue=4e-33,
Organism=Saccharomyces cerevisiae, GI6323118, Length=388, Percent_Identity=28.0927835051546, Blast_Score=127, Evalue=3e-30,
Organism=Drosophila melanogaster, GI24641770, Length=454, Percent_Identity=25.7709251101322, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24641760, Length=454, Percent_Identity=25.7709251101322, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24641768, Length=454, Percent_Identity=25.7709251101322, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24641766, Length=454, Percent_Identity=25.7709251101322, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24641764, Length=454, Percent_Identity=25.7709251101322, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI45551451, Length=454, Percent_Identity=25.7709251101322, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI18859735, Length=336, Percent_Identity=25.8928571428571, Blast_Score=100, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.1

Molecular weight: Translated: 49592; Mature: 49592

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTDITHEGANELTYEIREITEVAKTVEKHGINITWENIGDPIIKGEKIPEWMKEIIANT
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCHHHHHHHHHHH
LMDDYSYGYCPTKGLLETREFIADETNRKNGAQITPEDILFFNGLGEAITKIYGLLKKES
HHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHEECCHHHHHHHHHHHHHHCC
RVIGPSPAYPTHSSAEGLHSRCHPLMYRMDENDNWNPDIDDLTNKVKYNPTVSGILIINP
CCCCCCCCCCCCCCHHHHHHHHHHHHEEECCCCCCCCCHHHHHCCEECCCCEEEEEEEEC
GNPTGAVYSKKTLDEIVDLANEYDLFILCDEIYHNLVYNGKKHTNLSEVIDDVCGISLKG
CCCCCCCCCHHHHHHHHHHHCCCCEEEEHHHHHHHHHCCCCCCCCHHHHHHHHHCCEECC
ISKELPWPGARCGWMETYNYDKDPLFKRYIDGIVKFKMVEVCSTTLPQKVIPEIMGAPKF
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHH
KQYLKERNNYYEKASNFAYNKLNKIDGITINKTNGAFYSTVVFEEDKLNNSQSLKIENKE
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEEEEEEHHCCCCCCCEEECHHH
LQKYIENVSKGHKHDRKFVYNLLASSGICVVPMSSFNSELNGFRTTLLERDENKLKWTYE
HHHHHHHHHHCCHHHHHHHHHHHHCCCEEEEECHHHCHHHHHHHHHHHHCCCCHHEEHHH
SIAEKIEEYLNSN
HHHHHHHHHHCCC
>Mature Secondary Structure
MRTDITHEGANELTYEIREITEVAKTVEKHGINITWENIGDPIIKGEKIPEWMKEIIANT
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCHHHHHHHHHHH
LMDDYSYGYCPTKGLLETREFIADETNRKNGAQITPEDILFFNGLGEAITKIYGLLKKES
HHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHEECCHHHHHHHHHHHHHHCC
RVIGPSPAYPTHSSAEGLHSRCHPLMYRMDENDNWNPDIDDLTNKVKYNPTVSGILIINP
CCCCCCCCCCCCCCHHHHHHHHHHHHEEECCCCCCCCCHHHHHCCEECCCCEEEEEEEEC
GNPTGAVYSKKTLDEIVDLANEYDLFILCDEIYHNLVYNGKKHTNLSEVIDDVCGISLKG
CCCCCCCCCHHHHHHHHHHHCCCCEEEEHHHHHHHHHCCCCCCCCHHHHHHHHHCCEECC
ISKELPWPGARCGWMETYNYDKDPLFKRYIDGIVKFKMVEVCSTTLPQKVIPEIMGAPKF
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHH
KQYLKERNNYYEKASNFAYNKLNKIDGITINKTNGAFYSTVVFEEDKLNNSQSLKIENKE
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEEEEEEHHCCCCCCCEEECHHH
LQKYIENVSKGHKHDRKFVYNLLASSGICVVPMSSFNSELNGFRTTLLERDENKLKWTYE
HHHHHHHHHHCCHHHHHHHHHHHHCCCEEEEECHHHCHHHHHHHHHHHHCCCCHHEEHHH
SIAEKIEEYLNSN
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate; 2-oxoglutarate

Specific reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]