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The map label for this gene is cofG [H]

Identifier: 150401338

GI number: 150401338

Start: 935057

End: 936199

Strand: Reverse

Name: cofG [H]

Synonym: Maeo_0911

Alternate gene names: 150401338

Gene position: 936199-935057 (Counterclockwise)

Preceding gene: 150401339

Following gene: 150401337

Centisome position: 59.65

GC content: 29.57

Gene sequence:

>1143_bases
ATGAATAATATTAATGAAATAGAAGCGAAGCTTCTATACCCAAATCAAAGATTTGAGGATTTCCTATCGGAAATGGTGGA
ATTTCTAAATTCAAAAAATCCACAAGATATAATTGATAAATTAAGTCTGATAAATAATAATGGAAATAAAAATATCGGTA
ATGGCAATAAAACCAATAACAAAAAATATATCACTTACTCAAAAAATGTATTTATTCCAATATGTAATTGGTGCAAAAAC
ATTTGCGGATATTGCACATTTAGGAGAGAAAACTACAAACTGATGAATAAACAGGAAATAAAAGAAATATTATTAACTGG
AAATAAACATGGTTGTAGGGAGGCATTATTTACCTTTGGTGAAACCGTAGACGAAAATCCAAAAATAAAAGAAGATTTAA
AGAAAATGGGATACAACAATATTTTAGAATATTTATATGATATTTCCGACTGGTGTTTAACTAATACGGACCTATTGCCA
CATACAAATTGCGGGATATTATCCTATGAGGAATTAAAAACATTAAAAGAAGTAAATGCTTCCATGGGGCTCATGCTTGA
AAATTCTAGCGATAGGCTGTATAATACGATAGCCCACAAAGATAGCCCCGGAAAAGAACCAAAGAAACGATTAAAAATGA
TTGAAGATGCAGGAAAACTCAAAATACCTTTTACAACTGGAATATTGGTTGGTATTGGGGAAACCAATGAAGAAATTGTT
CAATCATTAGTTGATATTAACAATATTCATAAAAAATACGGTCATATTCAAGAAGTAATTATTCAAAATTTTAGGGCAAA
GGAAAGCATTCCTATGAGTAATTATGAAGAACCAACTCCTTTAAAAATGTTAAAAGTGCTAATTGTGGCAAAATTAATAT
TAAAAGATATATCTATTCAAGTTCCTCCTAATTTAAATTCTGAAACAGGTCAGCTGTTTTTATTTGCTGGTGTTGATGAT
TGGGGAGGGGTGTCGCCCATTACAAAAGATTTTGTAAATCCAGAGGCACCATGGCCAAAAATAGAGGAATTAAAAAAATA
TACCGAAGAATTTGGATATTCGTTAAAAGAAAGATTGCCAGTTTATGAAAAATATATCAATGAAAATTGGTTAAGTTGTA
AAGTTTTAGAAAAAATAAAATAG

Upstream 100 bases:

>100_bases
TATTATAGGGGATACGATATATTTGATAAAATATGTGAGGAAATGGAACAATTTTTAATTGAAAAAAATATTAAATTAAA
AGATATTGTTGGGGGAGCTC

Downstream 100 bases:

>100_bases
TAAAAACTTAAAAAAGGTAGATTCAGGTCGGGTAAGTTTCATCATAAAATCAGACAACCCTCTTTTCATCATTATCTACT
TTAAGCATGTGTTCGCATGT

Product: FO synthase subunit 1

Products: NA

Alternate protein names: 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit 1 [H]

Number of amino acids: Translated: 380; Mature: 380

Protein sequence:

>380_residues
MNNINEIEAKLLYPNQRFEDFLSEMVEFLNSKNPQDIIDKLSLINNNGNKNIGNGNKTNNKKYITYSKNVFIPICNWCKN
ICGYCTFRRENYKLMNKQEIKEILLTGNKHGCREALFTFGETVDENPKIKEDLKKMGYNNILEYLYDISDWCLTNTDLLP
HTNCGILSYEELKTLKEVNASMGLMLENSSDRLYNTIAHKDSPGKEPKKRLKMIEDAGKLKIPFTTGILVGIGETNEEIV
QSLVDINNIHKKYGHIQEVIIQNFRAKESIPMSNYEEPTPLKMLKVLIVAKLILKDISIQVPPNLNSETGQLFLFAGVDD
WGGVSPITKDFVNPEAPWPKIEELKKYTEEFGYSLKERLPVYEKYINENWLSCKVLEKIK

Sequences:

>Translated_380_residues
MNNINEIEAKLLYPNQRFEDFLSEMVEFLNSKNPQDIIDKLSLINNNGNKNIGNGNKTNNKKYITYSKNVFIPICNWCKN
ICGYCTFRRENYKLMNKQEIKEILLTGNKHGCREALFTFGETVDENPKIKEDLKKMGYNNILEYLYDISDWCLTNTDLLP
HTNCGILSYEELKTLKEVNASMGLMLENSSDRLYNTIAHKDSPGKEPKKRLKMIEDAGKLKIPFTTGILVGIGETNEEIV
QSLVDINNIHKKYGHIQEVIIQNFRAKESIPMSNYEEPTPLKMLKVLIVAKLILKDISIQVPPNLNSETGQLFLFAGVDD
WGGVSPITKDFVNPEAPWPKIEELKKYTEEFGYSLKERLPVYEKYINENWLSCKVLEKIK
>Mature_380_residues
MNNINEIEAKLLYPNQRFEDFLSEMVEFLNSKNPQDIIDKLSLINNNGNKNIGNGNKTNNKKYITYSKNVFIPICNWCKN
ICGYCTFRRENYKLMNKQEIKEILLTGNKHGCREALFTFGETVDENPKIKEDLKKMGYNNILEYLYDISDWCLTNTDLLP
HTNCGILSYEELKTLKEVNASMGLMLENSSDRLYNTIAHKDSPGKEPKKRLKMIEDAGKLKIPFTTGILVGIGETNEEIV
QSLVDINNIHKKYGHIQEVIIQNFRAKESIPMSNYEEPTPLKMLKVLIVAKLILKDISIQVPPNLNSETGQLFLFAGVDD
WGGVSPITKDFVNPEAPWPKIEELKKYTEEFGYSLKERLPVYEKYINENWLSCKVLEKIK

Specific function: Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) [H]

COG id: COG1060

COG function: function code HR; Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the radical SAM superfamily. CofG family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006638
- InterPro:   IPR019939
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM [H]

EC number: NA

Molecular weight: Translated: 43809; Mature: 43809

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNINEIEAKLLYPNQRFEDFLSEMVEFLNSKNPQDIIDKLSLINNNGNKNIGNGNKTNN
CCCHHHHHHEEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCC
KKYITYSKNVFIPICNWCKNICGYCTFRRENYKLMNKQEIKEILLTGNKHGCREALFTFG
CEEEEECCCEEEEHHHHHHHHHHHEEECCCCCHHCCHHHHHHHHHCCCCCHHHHHHHHHC
ETVDENPKIKEDLKKMGYNNILEYLYDISDWCLTNTDLLPHTNCGILSYEELKTLKEVNA
CCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHH
SMGLMLENSSDRLYNTIAHKDSPGKEPKKRLKMIEDAGKLKIPFTTGILVGIGETNEEIV
HHCEEEECCCHHHHHHHHCCCCCCCCHHHHHHHHHCCCCEEEEEECCEEEECCCCHHHHH
QSLVDINNIHKKYGHIQEVIIQNFRAKESIPMSNYEEPTPLKMLKVLIVAKLILKDISIQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCEE
VPPNLNSETGQLFLFAGVDDWGGVSPITKDFVNPEAPWPKIEELKKYTEEFGYSLKERLP
CCCCCCCCCCCEEEEECCCCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHHCC
VYEKYINENWLSCKVLEKIK
HHHHHHCCCCCEEHHHHHCC
>Mature Secondary Structure
MNNINEIEAKLLYPNQRFEDFLSEMVEFLNSKNPQDIIDKLSLINNNGNKNIGNGNKTNN
CCCHHHHHHEEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCC
KKYITYSKNVFIPICNWCKNICGYCTFRRENYKLMNKQEIKEILLTGNKHGCREALFTFG
CEEEEECCCEEEEHHHHHHHHHHHEEECCCCCHHCCHHHHHHHHHCCCCCHHHHHHHHHC
ETVDENPKIKEDLKKMGYNNILEYLYDISDWCLTNTDLLPHTNCGILSYEELKTLKEVNA
CCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHH
SMGLMLENSSDRLYNTIAHKDSPGKEPKKRLKMIEDAGKLKIPFTTGILVGIGETNEEIV
HHCEEEECCCHHHHHHHHCCCCCCCCHHHHHHHHHCCCCEEEEEECCEEEECCCCHHHHH
QSLVDINNIHKKYGHIQEVIIQNFRAKESIPMSNYEEPTPLKMLKVLIVAKLILKDISIQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCEE
VPPNLNSETGQLFLFAGVDDWGGVSPITKDFVNPEAPWPKIEELKKYTEEFGYSLKERLP
CCCCCCCCCCCEEEEECCCCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHHCC
VYEKYINENWLSCKVLEKIK
HHHHHHCCCCCEEHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA