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The map label for this gene is map [H]

Identifier: 150401298

GI number: 150401298

Start: 896646

End: 897533

Strand: Reverse

Name: map [H]

Synonym: Maeo_0870

Alternate gene names: 150401298

Gene position: 897533-896646 (Counterclockwise)

Preceding gene: 150401299

Following gene: 150401297

Centisome position: 57.19

GC content: 33.78

Gene sequence:

>888_bases
ATGACCAATGAAGAAATATATAATAAATTAAAAAAAGCTGGAGAAATTCATAAAATCGTTATGGAGGAAGGTATTAAATT
AATAAAAAAAGATGCCAAATTATATGATGTTGCGGAGCATGTTGAAAATAGAACAAAGGAATTAGGTGGAGAAATAGCAT
TTCCATGCAATATTTCTATAAACGATATTGCAGCACATTATACTCCATATTATGGGGATAAATCCGTATTTTCTGAAAAT
GACATCATAAAGCTTGATGTTGGAGTTCATGTAGATGGATATATTGCAGATGGTGCTAAAACTGTTGATTTATCCAACTC
ATACAAGGATTTAGTAAAGGCGTCGGAAGATGCCTTAAAAACTGTAATAAATGAGGTAGAACCACCGATGAATGTGGGGG
AAATGGGAAAAATAATAAAAGAAGTAATTAACAGCTATGGGTATAAACCAATATCCAACCTTTCAGGGCATGTTATGGGG
CAATATGATTTACATTCTGGAATATGCGTTCCAAATGTGCCAGAAAATACAAAATATACAATTGATGTTGGGGATATTGT
AGCAATCGAGCCATTTGCCACAGATGGGCATGGTCAGGTAATAGATGGAAAAGAAAAATATATATACAAATACATAGCTC
CGCGACCTGTTAGGCTTCCATCTGCTCGAAAATTGTTGGGAATTATTGAAAAAAATCATGCATATTTGCCATTTGCAGAA
AGATGGTTTTCAAAAATTCCAAAACATACCATGGCACTTAGAACCCTTATGAATTCAGGCTGTATTTATGGTTATCCTAC
ACTTATTGACAGAGGTGGCGGAATGGTAAGTCAGGCAGAGCACACAATTTATATTGGAGAAGATAAAATAGAAATAATTA
CAAAATAA

Upstream 100 bases:

>100_bases
ATGAAGATATACTAACAATTGTTATTAAAAGAACTAATTAAAATAATAAATAAAAATATAGGAGCTCCTTGGAGCTCCAA
TTAATTTTAATGATGATAAA

Downstream 100 bases:

>100_bases
AAGGAATATATAAGAATATATGCAGAATATAATACAAATATAAGTTGGTGATTATATGATTGTAATTCTTAACAATGGCG
GTCAATATGTCCATAGAATT

Product: methionine aminopeptidase

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 295; Mature: 294

Protein sequence:

>295_residues
MTNEEIYNKLKKAGEIHKIVMEEGIKLIKKDAKLYDVAEHVENRTKELGGEIAFPCNISINDIAAHYTPYYGDKSVFSEN
DIIKLDVGVHVDGYIADGAKTVDLSNSYKDLVKASEDALKTVINEVEPPMNVGEMGKIIKEVINSYGYKPISNLSGHVMG
QYDLHSGICVPNVPENTKYTIDVGDIVAIEPFATDGHGQVIDGKEKYIYKYIAPRPVRLPSARKLLGIIEKNHAYLPFAE
RWFSKIPKHTMALRTLMNSGCIYGYPTLIDRGGGMVSQAEHTIYIGEDKIEIITK

Sequences:

>Translated_295_residues
MTNEEIYNKLKKAGEIHKIVMEEGIKLIKKDAKLYDVAEHVENRTKELGGEIAFPCNISINDIAAHYTPYYGDKSVFSEN
DIIKLDVGVHVDGYIADGAKTVDLSNSYKDLVKASEDALKTVINEVEPPMNVGEMGKIIKEVINSYGYKPISNLSGHVMG
QYDLHSGICVPNVPENTKYTIDVGDIVAIEPFATDGHGQVIDGKEKYIYKYIAPRPVRLPSARKLLGIIEKNHAYLPFAE
RWFSKIPKHTMALRTLMNSGCIYGYPTLIDRGGGMVSQAEHTIYIGEDKIEIITK
>Mature_294_residues
TNEEIYNKLKKAGEIHKIVMEEGIKLIKKDAKLYDVAEHVENRTKELGGEIAFPCNISINDIAAHYTPYYGDKSVFSEND
IIKLDVGVHVDGYIADGAKTVDLSNSYKDLVKASEDALKTVINEVEPPMNVGEMGKIIKEVINSYGYKPISNLSGHVMGQ
YDLHSGICVPNVPENTKYTIDVGDIVAIEPFATDGHGQVIDGKEKYIYKYIAPRPVRLPSARKLLGIIEKNHAYLPFAER
WFSKIPKHTMALRTLMNSGCIYGYPTLIDRGGGMVSQAEHTIYIGEDKIEIITK

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI5803092, Length=315, Percent_Identity=34.6031746031746, Blast_Score=182, Evalue=3e-46,
Organism=Homo sapiens, GI124494254, Length=285, Percent_Identity=24.2105263157895, Blast_Score=98, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17544396, Length=314, Percent_Identity=33.1210191082803, Blast_Score=166, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI17542840, Length=320, Percent_Identity=24.6875, Blast_Score=94, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6319380, Length=318, Percent_Identity=34.2767295597484, Blast_Score=166, Evalue=4e-42,
Organism=Drosophila melanogaster, GI17137568, Length=313, Percent_Identity=33.8658146964856, Blast_Score=176, Evalue=2e-44,
Organism=Drosophila melanogaster, GI24658585, Length=320, Percent_Identity=23.4375, Blast_Score=95, Evalue=6e-20,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002468
- InterPro:   IPR018349
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 32879; Mature: 32748

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS01202 MAP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNEEIYNKLKKAGEIHKIVMEEGIKLIKKDAKLYDVAEHVENRTKELGGEIAFPCNISI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCH
NDIAAHYTPYYGDKSVFSENDIIKLDVGVHVDGYIADGAKTVDLSNSYKDLVKASEDALK
HHHHHHCCCCCCCCCCCCCCCEEEEEECEEECCEEECCEEEEECCHHHHHHHHCCHHHHH
TVINEVEPPMNVGEMGKIIKEVINSYGYKPISNLSGHVMGQYDLHSGICVPNVPENTKYT
HHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCEEE
IDVGDIVAIEPFATDGHGQVIDGKEKYIYKYIAPRPVRLPSARKLLGIIEKNHAYLPFAE
EECCCEEEEECCCCCCCCCEECCCHHEEEEEECCCCCCCCCHHHHHHHHHCCCCCCCHHH
RWFSKIPKHTMALRTLMNSGCIYGYPTLIDRGGGMVSQAEHTIYIGEDKIEIITK
HHHHHCCHHHHHHHHHHHCCCEECCHHHHCCCCCCCCCCCEEEEECCCCEEEEEC
>Mature Secondary Structure 
TNEEIYNKLKKAGEIHKIVMEEGIKLIKKDAKLYDVAEHVENRTKELGGEIAFPCNISI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCH
NDIAAHYTPYYGDKSVFSENDIIKLDVGVHVDGYIADGAKTVDLSNSYKDLVKASEDALK
HHHHHHCCCCCCCCCCCCCCCEEEEEECEEECCEEECCEEEEECCHHHHHHHHCCHHHHH
TVINEVEPPMNVGEMGKIIKEVINSYGYKPISNLSGHVMGQYDLHSGICVPNVPENTKYT
HHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCEEE
IDVGDIVAIEPFATDGHGQVIDGKEKYIYKYIAPRPVRLPSARKLLGIIEKNHAYLPFAE
EECCCEEEEECCCCCCCCCEECCCHHEEEEEECCCCCCCCCHHHHHHHHHCCCCCCCHHH
RWFSKIPKHTMALRTLMNSGCIYGYPTLIDRGGGMVSQAEHTIYIGEDKIEIITK
HHHHHCCHHHHHHHHHHHCCCEECCHHHHCCCCCCCCCCCEEEEECCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]