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The map label for this gene is nadX

Identifier: 150401276

GI number: 150401276

Start: 875762

End: 876562

Strand: Direct

Name: nadX

Synonym: Maeo_0848

Alternate gene names: 150401276

Gene position: 875762-876562 (Clockwise)

Preceding gene: 150401275

Following gene: 150401277

Centisome position: 55.8

GC content: 32.21

Gene sequence:

>801_bases
ATGTTAAAAATAGGCATAATAGGGTGCGGAACAATAGCTACGATGATAGCAAAAGCCATTAACTACAAAAAAATCAACGG
GACTATTGTAGCACTATATGACAAACATAACGATAAATCACAAGATTTAAATAAATTAACTAATGCCAAAATATGCGATA
GTATAGATAAGCTTGTAAAAGAAGAATTAGATATAGTAATAGAATGTGCATCAATTAAATCAGTAGAAGAAGTTGCCACC
AAATCATTAAATCATAAAAAAAATGTAGTTATTATGAGTGTTGGAGCTTTGGCAGATAAAAATTTATTTTCAAAATTATA
TAAAATTGCCAACGATAACGAAAAAAAGATATTTGTTCCGTCAGGAGCTATTGCAGGAGTTGATGCTATTAAAACCGCAT
CAATAGGACGAATAGATGAAGTGAGCTTAATCACTACAAAGCCAGTTTATGGATTGGAAGATGCCTTAAAAAATAAAGGT
ATAGATACTACAAATATATCAGAACCTACGGTTGTTTTTGAAGGAACTGTGTTTGATGCCATTAAAGAATTCCCTCAAAA
CATAAATGTATCCGTAGTGTTATCCATTGCCTCAAAAATTCCTGCAAAGGTTAAAATTGTAGCTGACCCGTCGGCAACAT
CAAATAAACACGAAATAATTGTAAAAGGTTCAATAGGCACAATTAAAACGGTGGTGGAAAATAATCCCTGTAAAGACAAC
CCCAAAACTTCGGCGTTAGCTGCCTATTCTGTTATTAGATTGTTAAAAGATTTGTCTGAACCAATAATTGTTGGAACATA
A

Upstream 100 bases:

>100_bases
ATATTCTAAATATAATTTTTATTTTGCATAATTTGTATGGATTTTTTTTATTATATTGATAGTTTTTTATTTTATAATTT
AATATTAGAGTGAATGAAAA

Downstream 100 bases:

>100_bases
AATTTTCCAAAACACATAAAAAAATACATAAAATTATATATTATTTATTTCTATTTTTATTTACAATTAATTATTAGCTG
TTAATTATTAGCGAATTTAT

Product: L-aspartate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 266; Mature: 266

Protein sequence:

>266_residues
MLKIGIIGCGTIATMIAKAINYKKINGTIVALYDKHNDKSQDLNKLTNAKICDSIDKLVKEELDIVIECASIKSVEEVAT
KSLNHKKNVVIMSVGALADKNLFSKLYKIANDNEKKIFVPSGAIAGVDAIKTASIGRIDEVSLITTKPVYGLEDALKNKG
IDTTNISEPTVVFEGTVFDAIKEFPQNINVSVVLSIASKIPAKVKIVADPSATSNKHEIIVKGSIGTIKTVVENNPCKDN
PKTSALAAYSVIRLLKDLSEPIIVGT

Sequences:

>Translated_266_residues
MLKIGIIGCGTIATMIAKAINYKKINGTIVALYDKHNDKSQDLNKLTNAKICDSIDKLVKEELDIVIECASIKSVEEVAT
KSLNHKKNVVIMSVGALADKNLFSKLYKIANDNEKKIFVPSGAIAGVDAIKTASIGRIDEVSLITTKPVYGLEDALKNKG
IDTTNISEPTVVFEGTVFDAIKEFPQNINVSVVLSIASKIPAKVKIVADPSATSNKHEIIVKGSIGTIKTVVENNPCKDN
PKTSALAAYSVIRLLKDLSEPIIVGT
>Mature_266_residues
MLKIGIIGCGTIATMIAKAINYKKINGTIVALYDKHNDKSQDLNKLTNAKICDSIDKLVKEELDIVIECASIKSVEEVAT
KSLNHKKNVVIMSVGALADKNLFSKLYKIANDNEKKIFVPSGAIAGVDAIKTASIGRIDEVSLITTKPVYGLEDALKNKG
IDTTNISEPTVVFEGTVFDAIKEFPQNINVSVVLSIASKIPAKVKIVADPSATSNKHEIIVKGSIGTIKTVVENNPCKDN
PKTSALAAYSVIRLLKDLSEPIIVGT

Specific function: Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate

COG id: COG1712

COG function: function code R; Predicted dinucleotide-utilizing enzyme

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the L-aspartate dehydrogenase family

Homologues:

Organism=Caenorhabditis elegans, GI71984591, Length=274, Percent_Identity=24.8175182481752, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ASPD_META3 (A6UVA8)

Other databases:

- EMBL:   CP000743
- RefSeq:   YP_001325042.1
- ProteinModelPortal:   A6UVA8
- SMR:   A6UVA8
- STRING:   A6UVA8
- GeneID:   5326330
- GenomeReviews:   CP000743_GR
- KEGG:   mae:Maeo_0848
- eggNOG:   arNOG05209
- HOGENOM:   HBG649642
- OMA:   ECAGHSA
- ProtClustDB:   PRK13304
- BioCyc:   MAEO419665:MAEO_0848-MONOMER
- HAMAP:   MF_01265
- InterPro:   IPR005106
- InterPro:   IPR002811
- InterPro:   IPR011182
- InterPro:   IPR020626
- InterPro:   IPR022487
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PIRSF:   PIRSF005227
- TIGRFAMs:   TIGR03855

Pfam domain/function: PF01958 DUF108; PF03447 NAD_binding_3

EC number: =1.4.1.21

Molecular weight: Translated: 28533; Mature: 28533

Theoretical pI: Translated: 9.09; Mature: 9.09

Prosite motif: NA

Important sites: ACT_SITE 217-217 BINDING 123-123 BINDING 189-189

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKIGIIGCGTIATMIAKAINYKKINGTIVALYDKHNDKSQDLNKLTNAKICDSIDKLVK
CEEEEEEEHHHHHHHHHHHHCEEEECCEEEEEEECCCCCHHHHHHHCCCHHHHHHHHHHH
EELDIVIECASIKSVEEVATKSLNHKKNVVIMSVGALADKNLFSKLYKIANDNEKKIFVP
HHHHEEEEECCCHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHCCCCCCEEEEC
SGAIAGVDAIKTASIGRIDEVSLITTKPVYGLEDALKNKGIDTTNISEPTVVFEGTVFDA
CCCCCCCHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHCCCCCCCCCCCEEEEECHHHHH
IKEFPQNINVSVVLSIASKIPAKVKIVADPSATSNKHEIIVKGSIGTIKTVVENNPCKDN
HHHCCCCCCCEEEEEEHHHCCCEEEEEECCCCCCCCCEEEEECCCCEEEHEECCCCCCCC
PKTSALAAYSVIRLLKDLSEPIIVGT
CCHHHHHHHHHHHHHHHCCCCEEECC
>Mature Secondary Structure
MLKIGIIGCGTIATMIAKAINYKKINGTIVALYDKHNDKSQDLNKLTNAKICDSIDKLVK
CEEEEEEEHHHHHHHHHHHHCEEEECCEEEEEEECCCCCHHHHHHHCCCHHHHHHHHHHH
EELDIVIECASIKSVEEVATKSLNHKKNVVIMSVGALADKNLFSKLYKIANDNEKKIFVP
HHHHEEEEECCCHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHCCCCCCEEEEC
SGAIAGVDAIKTASIGRIDEVSLITTKPVYGLEDALKNKGIDTTNISEPTVVFEGTVFDA
CCCCCCCHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHCCCCCCCCCCCEEEEECHHHHH
IKEFPQNINVSVVLSIASKIPAKVKIVADPSATSNKHEIIVKGSIGTIKTVVENNPCKDN
HHHCCCCCCCEEEEEEHHHCCCEEEEEECCCCCCCCCEEEEECCCCEEEHEECCCCCCCC
PKTSALAAYSVIRLLKDLSEPIIVGT
CCHHHHHHHHHHHHHHHCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA