Click here to switch to the map view.

The map label for this gene is bioA [H]

Identifier: 150401191

GI number: 150401191

Start: 783941

End: 785374

Strand: Direct

Name: bioA [H]

Synonym: Maeo_0762

Alternate gene names: 150401191

Gene position: 783941-785374 (Clockwise)

Preceding gene: 150401190

Following gene: 150401192

Centisome position: 49.95

GC content: 29.99

Gene sequence:

>1434_bases
ATGAACAATAATTTAAATCCTAAAAAAATAATTGAAATGGATAAAAAATTTGTATGGCATCCATATACCCAAATGAAAGA
ATACAACCAAAACCCCAATAATATAATAATTGAAAGAGGTGAAGGAAATTATTTAATAGATATACGAAATAAAAAATATC
TTGATGCTGTTTCTTCTATTTGGTGTAATTTATTAGGACATAGTGAAAAAAGAATAATAAATGCAATTAAAGAACAGGCA
GATAAAATATGCCATTCCACATTATTGGGTTGTGGAAATGTTCCATCAACAATATTGGCGGAAAAGGTAATTAATATTAC
TCCCCCGCATTTGAAAAAAGTATTTTATTCAGAAGATGGGTCGGAAGCTGTTGAAATAGCTGTAAAAATGGCTTTTGAAT
ATTGTCAATTGAAAGATAGTAAAAATAATAAAGATAATAATAACAATAACCAAACAGCACAACCTCAAAGGACAAAATTT
GTTTCTGTAAAAGAGGGATACCACGGGGACACAATTGGAACAATGAGTGTAGGGGGGAGCTCCACATTTCACGGTATGTT
TAAACCGTTGTTGTTTAATGGATATTTTGCAAATACTCCTTATTGTTATAGATGCCAATATCATAATTTTAAAGATACAG
ACGATAGAAACAAATGCGGTTGTGAAATGGACTGTTTAAAGGAAATGTTAAATTTAATAGAATCCCACAAAGAAGAACTA
TTTTGCGTAATTCTTGAAGCTGGAGTTATGGGCTCAGCAGGTATAATTCCATATCCAGATGGATATATCGAAAAAGTTGC
AGAGCTCTGCAAAAAACACAATATTATATTAATATTAGATGAAGTTGCCACATATGGGAGACTTGGAAAATATTTATTTT
CAGACAATGAAACCCTTAAAAAATTAAATAAACCAGATATAATATGTATAGGAAAAGGAATAACTGGCGGTTATTTACCA
TTAGCTTTAACAATTACAACGGAAGAAATATATAATGAATTTTTAGGGGATTTTAAAGACTGTGTGCAATTTTTCCACGG
GCATACCTATACAGGAAATCAACTATTATGCGCCTCTGCAATTGCTACCCTTGATGTATTGGAAGATGACAAAATATTTG
AAAATACAAAGGATAAAATAAAATACCTCCATAATTCAATGGACAAATTAAAAGAACTGAATAATGTTGGAGATATTAGG
AAAAAAGGATTTATGATAGGTATAGAACTTGTAAAAGACAAAGAAACAAAAGAGCCATTCCCATATGAATTTAAAGCAGG
ATATAAAGTCGCAGATAAATTACTTGAAAAAGGAATATATATGAGACCAATATTTAACACAATTATAATAGTCCCCCCTT
TAACCATAACCGCCGAAGAAATATCATTTTTGGTTGATGGATTATATAATTCAATTAAAGAAATTTTTGAATAA

Upstream 100 bases:

>100_bases
GACCATATATTATTTGTTGGGATTTGGAATAAACAATAAATTTTAAGCAAATGTTCGCCGATTTACCCCCCCTATTTTTT
TAAATATTTTTGGTGATATA

Downstream 100 bases:

>100_bases
TATTTTTTTATTCATATCTTAACATACCATAATTATAAATAACAATTTAATACCATAAAATATTATGAAAGAATTATATC
GACAGCTAATTCATTTAATA

Product: aminotransferase class-III

Products: NA

Alternate protein names: 7,8-diamino-pelargonic acid aminotransferase; DAPA AT; DAPA aminotransferase; Diaminopelargonic acid synthase [H]

Number of amino acids: Translated: 477; Mature: 477

Protein sequence:

>477_residues
MNNNLNPKKIIEMDKKFVWHPYTQMKEYNQNPNNIIIERGEGNYLIDIRNKKYLDAVSSIWCNLLGHSEKRIINAIKEQA
DKICHSTLLGCGNVPSTILAEKVINITPPHLKKVFYSEDGSEAVEIAVKMAFEYCQLKDSKNNKDNNNNNQTAQPQRTKF
VSVKEGYHGDTIGTMSVGGSSTFHGMFKPLLFNGYFANTPYCYRCQYHNFKDTDDRNKCGCEMDCLKEMLNLIESHKEEL
FCVILEAGVMGSAGIIPYPDGYIEKVAELCKKHNIILILDEVATYGRLGKYLFSDNETLKKLNKPDIICIGKGITGGYLP
LALTITTEEIYNEFLGDFKDCVQFFHGHTYTGNQLLCASAIATLDVLEDDKIFENTKDKIKYLHNSMDKLKELNNVGDIR
KKGFMIGIELVKDKETKEPFPYEFKAGYKVADKLLEKGIYMRPIFNTIIIVPPLTITAEEISFLVDGLYNSIKEIFE

Sequences:

>Translated_477_residues
MNNNLNPKKIIEMDKKFVWHPYTQMKEYNQNPNNIIIERGEGNYLIDIRNKKYLDAVSSIWCNLLGHSEKRIINAIKEQA
DKICHSTLLGCGNVPSTILAEKVINITPPHLKKVFYSEDGSEAVEIAVKMAFEYCQLKDSKNNKDNNNNNQTAQPQRTKF
VSVKEGYHGDTIGTMSVGGSSTFHGMFKPLLFNGYFANTPYCYRCQYHNFKDTDDRNKCGCEMDCLKEMLNLIESHKEEL
FCVILEAGVMGSAGIIPYPDGYIEKVAELCKKHNIILILDEVATYGRLGKYLFSDNETLKKLNKPDIICIGKGITGGYLP
LALTITTEEIYNEFLGDFKDCVQFFHGHTYTGNQLLCASAIATLDVLEDDKIFENTKDKIKYLHNSMDKLKELNNVGDIR
KKGFMIGIELVKDKETKEPFPYEFKAGYKVADKLLEKGIYMRPIFNTIIIVPPLTITAEEISFLVDGLYNSIKEIFE
>Mature_477_residues
MNNNLNPKKIIEMDKKFVWHPYTQMKEYNQNPNNIIIERGEGNYLIDIRNKKYLDAVSSIWCNLLGHSEKRIINAIKEQA
DKICHSTLLGCGNVPSTILAEKVINITPPHLKKVFYSEDGSEAVEIAVKMAFEYCQLKDSKNNKDNNNNNQTAQPQRTKF
VSVKEGYHGDTIGTMSVGGSSTFHGMFKPLLFNGYFANTPYCYRCQYHNFKDTDDRNKCGCEMDCLKEMLNLIESHKEEL
FCVILEAGVMGSAGIIPYPDGYIEKVAELCKKHNIILILDEVATYGRLGKYLFSDNETLKKLNKPDIICIGKGITGGYLP
LALTITTEEIYNEFLGDFKDCVQFFHGHTYTGNQLLCASAIATLDVLEDDKIFENTKDKIKYLHNSMDKLKELNNVGDIR
KKGFMIGIELVKDKETKEPFPYEFKAGYKVADKLLEKGIYMRPIFNTIIIVPPLTITAEEISFLVDGLYNSIKEIFE

Specific function: Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor [H]

COG id: COG0161

COG function: function code H; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily [H]

Homologues:

Organism=Homo sapiens, GI13994255, Length=500, Percent_Identity=28, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI4557809, Length=438, Percent_Identity=28.0821917808219, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI37574042, Length=439, Percent_Identity=26.4236902050114, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI226442705, Length=439, Percent_Identity=26.1958997722096, Blast_Score=122, Evalue=7e-28,
Organism=Homo sapiens, GI226442709, Length=409, Percent_Identity=26.4058679706601, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI24119277, Length=463, Percent_Identity=23.110151187905, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI284507298, Length=216, Percent_Identity=32.8703703703704, Blast_Score=100, Evalue=4e-21,
Organism=Escherichia coli, GI1786991, Length=466, Percent_Identity=29.1845493562232, Blast_Score=204, Evalue=9e-54,
Organism=Escherichia coli, GI145693181, Length=447, Percent_Identity=26.8456375838926, Blast_Score=162, Evalue=4e-41,
Organism=Escherichia coli, GI1788044, Length=447, Percent_Identity=26.6219239373602, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1789759, Length=381, Percent_Identity=27.0341207349081, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1789016, Length=436, Percent_Identity=24.5412844036697, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1787560, Length=431, Percent_Identity=24.5939675174014, Blast_Score=94, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI32564660, Length=467, Percent_Identity=28.9079229122056, Blast_Score=152, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI25144271, Length=479, Percent_Identity=26.5135699373695, Blast_Score=132, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI71992977, Length=401, Percent_Identity=27.1820448877805, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI25144274, Length=231, Percent_Identity=31.1688311688312, Blast_Score=100, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6324386, Length=491, Percent_Identity=28.1059063136456, Blast_Score=176, Evalue=6e-45,
Organism=Saccharomyces cerevisiae, GI6323470, Length=478, Percent_Identity=26.3598326359833, Blast_Score=137, Evalue=4e-33,
Organism=Saccharomyces cerevisiae, GI6324432, Length=464, Percent_Identity=26.2931034482759, Blast_Score=123, Evalue=8e-29,
Organism=Drosophila melanogaster, GI28574759, Length=469, Percent_Identity=28.3582089552239, Blast_Score=149, Evalue=5e-36,
Organism=Drosophila melanogaster, GI161085790, Length=464, Percent_Identity=27.5862068965517, Blast_Score=148, Evalue=7e-36,
Organism=Drosophila melanogaster, GI21357415, Length=449, Percent_Identity=26.0579064587973, Blast_Score=129, Evalue=4e-30,
Organism=Drosophila melanogaster, GI21356575, Length=473, Percent_Identity=23.4672304439746, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI281366494, Length=395, Percent_Identity=24.3037974683544, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24667139, Length=395, Percent_Identity=24.3037974683544, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24667143, Length=395, Percent_Identity=24.3037974683544, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR005815
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.62 [H]

Molecular weight: Translated: 54281; Mature: 54281

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNNLNPKKIIEMDKKFVWHPYTQMKEYNQNPNNIIIERGEGNYLIDIRNKKYLDAVSSI
CCCCCCHHHHHHHHHHHEECCHHHHHHHCCCCCEEEEECCCCCEEEEECCCHHHHHHHHH
WCNLLGHSEKRIINAIKEQADKICHSTLLGCGNVPSTILAEKVINITPPHLKKVFYSEDG
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHCCCC
SEAVEIAVKMAFEYCQLKDSKNNKDNNNNNQTAQPQRTKFVSVKEGYHGDTIGTMSVGGS
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHEEEEECCCCCCCCCEEEECCCC
STFHGMFKPLLFNGYFANTPYCYRCQYHNFKDTDDRNKCGCEMDCLKEMLNLIESHKEEL
CHHHHHHHHHHHCCEECCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHE
FCVILEAGVMGSAGIIPYPDGYIEKVAELCKKHNIILILDEVATYGRLGKYLFSDNETLK
EEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHCCCHHHH
KLNKPDIICIGKGITGGYLPLALTITTEEIYNEFLGDFKDCVQFFHGHTYTGNQLLCASA
HCCCCCEEEEECCCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
IATLDVLEDDKIFENTKDKIKYLHNSMDKLKELNNVGDIRKKGFMIGIELVKDKETKEPF
HHHHHHHCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCC
PYEFKAGYKVADKLLEKGIYMRPIFNTIIIVPPLTITAEEISFLVDGLYNSIKEIFE
CCCCCCCHHHHHHHHHCCCEEEEHHCEEEEECCCEEEHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MNNNLNPKKIIEMDKKFVWHPYTQMKEYNQNPNNIIIERGEGNYLIDIRNKKYLDAVSSI
CCCCCCHHHHHHHHHHHEECCHHHHHHHCCCCCEEEEECCCCCEEEEECCCHHHHHHHHH
WCNLLGHSEKRIINAIKEQADKICHSTLLGCGNVPSTILAEKVINITPPHLKKVFYSEDG
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHCCCC
SEAVEIAVKMAFEYCQLKDSKNNKDNNNNNQTAQPQRTKFVSVKEGYHGDTIGTMSVGGS
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHEEEEECCCCCCCCCEEEECCCC
STFHGMFKPLLFNGYFANTPYCYRCQYHNFKDTDDRNKCGCEMDCLKEMLNLIESHKEEL
CHHHHHHHHHHHCCEECCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHE
FCVILEAGVMGSAGIIPYPDGYIEKVAELCKKHNIILILDEVATYGRLGKYLFSDNETLK
EEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHCCCHHHH
KLNKPDIICIGKGITGGYLPLALTITTEEIYNEFLGDFKDCVQFFHGHTYTGNQLLCASA
HCCCCCEEEEECCCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
IATLDVLEDDKIFENTKDKIKYLHNSMDKLKELNNVGDIRKKGFMIGIELVKDKETKEPF
HHHHHHHCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCC
PYEFKAGYKVADKLLEKGIYMRPIFNTIIIVPPLTITAEEISFLVDGLYNSIKEIFE
CCCCCCCHHHHHHHHHCCCEEEEHHCEEEEECCCEEEHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]