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The map label for this gene is sppA [C]

Identifier: 150401144

GI number: 150401144

Start: 734089

End: 734961

Strand: Direct

Name: sppA [C]

Synonym: Maeo_0715

Alternate gene names: 150401144

Gene position: 734089-734961 (Clockwise)

Preceding gene: 150401143

Following gene: 150401145

Centisome position: 46.77

GC content: 34.14

Gene sequence:

>873_bases
ATGGCCATATTATTCATGCCAGATGGTAGCGGAAATAATATATTTTCATTTTGGAGTGATGAAGTTTCAATTATAGAATT
AACTGGCGAAATTAGTTCCAATGGTGGAGATGGGGGAGTATTTGGAGGATATTCTCCAAGTGCTGATGAATATATTAGAT
TATTAGATAATGCTGAAAATAACGATGGCGTAAAAGCAGTTGTATTAAAAATTAATTCTCCAGGAGGAGAAGTGGTGGCA
AGTGAAAAACTTGCAAGAAAAGTAAAAGAAGTTTCTGAAAAAAAGCCCGTTGTGGCATATATTGAAACTATTGGGGCTTC
TGGTGCATATATGGCAGCAGTGCCTTCCGATTATATTGTAGCCGAAAAACATTCAATGGTTGGAAGTATTGGGGTAATAA
TGGGACTATCTCATTATTATGAGCTTTATGAAAAAATTGGAATAAATACTACCACAATAAAAGCAGGAAAATATAAAGAT
ATCGGCTCACCAAATCGACCAATGACAGATGAAGAAAAAAAAATGTTAGAATCTATGACGGACGAAATGTATGGAGATTT
TATAAAATGGGTTGCTGAAAATAGGGGAATGGACATAAATAAAACCTACGAAGTAGCAGAAGGTAAAATATATACGGGAA
GCCAGGCTAAAAAAGCAGGATTAGTAGATGCCGTTGGTGTTGAACAGGATGCCATTGATAAAGCTTCTGAATTAGCAAAT
ATATCCAATCCTACCGTAGTCTATTATGATGCAAATAAACCAGCTGGATTATTTGGTTTATCTATTAATGATATTGTATA
TCATTTGGGTTATGGTATTGGCAGGGGTTTAAATCCAAACATAGAACAGAAAACTATTAAATTAAGTTATTAA

Upstream 100 bases:

>100_bases
TATAATTTATGCGGGCGATATTTTGAAAAATAAAAATATATATTTAATATTTGGGGCCTTGGTAGCATTATTGATATTAT
TATCTGTTGGGGCTCTAACA

Downstream 100 bases:

>100_bases
TATTAATTATAAAATTATTTATTAAAATATATTTTCTATTTTTTATTATTTTATTGTCTTCTTTGTTTATTAATTATTAA
TTTATCTAAATTTGGTGTAA

Product: signal peptide peptidase SppA, 36K type

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 290; Mature: 289

Protein sequence:

>290_residues
MAILFMPDGSGNNIFSFWSDEVSIIELTGEISSNGGDGGVFGGYSPSADEYIRLLDNAENNDGVKAVVLKINSPGGEVVA
SEKLARKVKEVSEKKPVVAYIETIGASGAYMAAVPSDYIVAEKHSMVGSIGVIMGLSHYYELYEKIGINTTTIKAGKYKD
IGSPNRPMTDEEKKMLESMTDEMYGDFIKWVAENRGMDINKTYEVAEGKIYTGSQAKKAGLVDAVGVEQDAIDKASELAN
ISNPTVVYYDANKPAGLFGLSINDIVYHLGYGIGRGLNPNIEQKTIKLSY

Sequences:

>Translated_290_residues
MAILFMPDGSGNNIFSFWSDEVSIIELTGEISSNGGDGGVFGGYSPSADEYIRLLDNAENNDGVKAVVLKINSPGGEVVA
SEKLARKVKEVSEKKPVVAYIETIGASGAYMAAVPSDYIVAEKHSMVGSIGVIMGLSHYYELYEKIGINTTTIKAGKYKD
IGSPNRPMTDEEKKMLESMTDEMYGDFIKWVAENRGMDINKTYEVAEGKIYTGSQAKKAGLVDAVGVEQDAIDKASELAN
ISNPTVVYYDANKPAGLFGLSINDIVYHLGYGIGRGLNPNIEQKTIKLSY
>Mature_289_residues
AILFMPDGSGNNIFSFWSDEVSIIELTGEISSNGGDGGVFGGYSPSADEYIRLLDNAENNDGVKAVVLKINSPGGEVVAS
EKLARKVKEVSEKKPVVAYIETIGASGAYMAAVPSDYIVAEKHSMVGSIGVIMGLSHYYELYEKIGINTTTIKAGKYKDI
GSPNRPMTDEEKKMLESMTDEMYGDFIKWVAENRGMDINKTYEVAEGKIYTGSQAKKAGLVDAVGVEQDAIDKASELANI
SNPTVVYYDANKPAGLFGLSINDIVYHLGYGIGRGLNPNIEQKTIKLSY

Specific function: Digestion Of The Cleaved Signal Peptides. This Activity Is Necessary To Maintain Proper Secretion Of Mature Proteins Across The Membrane. [C]

COG id: COG0616

COG function: function code OU; Periplasmic serine proteases (ClpP class)

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S49 family [H]

Homologues:

Organism=Escherichia coli, GI1788064, Length=231, Percent_Identity=31.6017316017316, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1787527, Length=170, Percent_Identity=30.5882352941176, Blast_Score=72, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004635
- InterPro:   IPR002142 [H]

Pfam domain/function: PF01343 Peptidase_S49 [H]

EC number: 3.4.21.-

Molecular weight: Translated: 31330; Mature: 31199

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAILFMPDGSGNNIFSFWSDEVSIIELTGEISSNGGDGGVFGGYSPSADEYIRLLDNAEN
CEEEEECCCCCCCEEEEECCCEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCCC
NDGVKAVVLKINSPGGEVVASEKLARKVKEVSEKKPVVAYIETIGASGAYMAAVPSDYIV
CCCEEEEEEEEECCCCCEEHHHHHHHHHHHHHHCCCEEEEEEHHCCCCEEEEECCCCEEE
AEKHSMVGSIGVIMGLSHYYELYEKIGINTTTIKAGKYKDIGSPNRPMTDEEKKMLESMT
ECHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHH
DEMYGDFIKWVAENRGMDINKTYEVAEGKIYTGSQAKKAGLVDAVGVEQDAIDKASELAN
HHHHHHHHHHHHHCCCCCCCCEEEECCCEEEECCCCCCCCCEEECCCCHHHHHHHHHHHC
ISNPTVVYYDANKPAGLFGLSINDIVYHLGYGIGRGLNPNIEQKTIKLSY
CCCCEEEEEECCCCCEEEECCHHHHHHHHHHHHCCCCCCCCCCCEEEECC
>Mature Secondary Structure 
AILFMPDGSGNNIFSFWSDEVSIIELTGEISSNGGDGGVFGGYSPSADEYIRLLDNAEN
EEEEECCCCCCCEEEEECCCEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCCC
NDGVKAVVLKINSPGGEVVASEKLARKVKEVSEKKPVVAYIETIGASGAYMAAVPSDYIV
CCCEEEEEEEEECCCCCEEHHHHHHHHHHHHHHCCCEEEEEEHHCCCCEEEEECCCCEEE
AEKHSMVGSIGVIMGLSHYYELYEKIGINTTTIKAGKYKDIGSPNRPMTDEEKKMLESMT
ECHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHH
DEMYGDFIKWVAENRGMDINKTYEVAEGKIYTGSQAKKAGLVDAVGVEQDAIDKASELAN
HHHHHHHHHHHHHCCCCCCCCEEEECCCEEEECCCCCCCCCEEECCCCHHHHHHHHHHHC
ISNPTVVYYDANKPAGLFGLSINDIVYHLGYGIGRGLNPNIEQKTIKLSY
CCCCEEEEEECCCCCEEEECCHHHHHHHHHHHHCCCCCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]