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The map label for this gene is yrbG [C]

Identifier: 150401145

GI number: 150401145

Start: 735065

End: 736057

Strand: Direct

Name: yrbG [C]

Synonym: Maeo_0716

Alternate gene names: 150401145

Gene position: 735065-736057 (Clockwise)

Preceding gene: 150401144

Following gene: 150401146

Centisome position: 46.83

GC content: 28.7

Gene sequence:

>993_bases
ATGGTAGAAATTTTATTTAGTGTATTTATTCTATTATTGGGTTTGGCATTACTTAATTATGGTAGTGATTGGTTTGTAGT
GGGGAGCTCCAAAGTAGCAAAACATTTAAATGTTTCAAATTTTGTAATTGGGGCAACAGTTGTTGCTTTTGGAACCTCAT
TACCTGAAATAATAACAAGCGTTTATGCATCATATATTGGCTCCACAGGAATAGCCGTAGGAAACTCATTAGGTAGTAAT
ATAGCCAATGTTGGATTAATATTGGGATTAAGTGCCCTAATTGCTCCAATATATATAAGAAAAGAAAATATTTTAAAAAA
CGGATATATTTATTTATTATTTACAATCATAGCATTTATATTAGGCTATGATGGTTTTAATTCAATTGATGGTATATTAT
TATTTATAATGCTAATTTCATACATAACATATACTATTAAAAAAGGAGGATGTTGCGAGGAAATGGGGGAAAATAATGGG
AGCATAGTTAAATCAGTGTTATTTACTATTTTAGGACTATTGGCAGTTATAGTTGGAAGTAGCCTATTTGTAAGTGGTGC
AAAAGATATTGCATTGTTTTTAGGCATATCTGATAAAATCATTGGATTTACCCTTGTTGCTTTTGGAACCTCATTACCTG
AATTGGTGGTTTCAATTACCGCAGTTAAAAGAAAACTGGGAGATATGGTAATTGGAAATATTATTGGTAGTAATATAGCA
AATATTGGCGGTGCATTGGCATTGGCTTCCATAATAAGCCCACTCCCAAAAGTTCCTTTTGAAATGACTGTAAATTTACT
TTTAACCTCATTGATGGTATTATTTATGTCCAAACATATTCTGGAATTTATTAAGAAAAATAAGGATAAAATACATAACA
AAAAAGATAATAACGATAATGAAACCATTTACTCAAAAATAAATAGAATTGATGGAACAATATTAATTTTAATTTATTTA
GGATTTATATTATTTATTTCCAATATATTATAA

Upstream 100 bases:

>100_bases
TAATTATAAAATTATTTATTAAAATATATTTTCTATTTTTTATTATTTTATTGTCTTCTTTGTTTATTAATTATTAATTT
ATCTAAATTTGGTGTAAATT

Downstream 100 bases:

>100_bases
ATAGATAGATATATAGATAAATAGATAAATAATAACACATCGTGATACAATGAAACAAATAAAATTAAAAATAAAATTAA
ATGGAGTATTTAAAGAATAT

Product: CaCA family Na(+)/Ca(+) antiporter

Products: Na (I) [Cytoplasm]; Ca (II) [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MVEILFSVFILLLGLALLNYGSDWFVVGSSKVAKHLNVSNFVIGATVVAFGTSLPEIITSVYASYIGSTGIAVGNSLGSN
IANVGLILGLSALIAPIYIRKENILKNGYIYLLFTIIAFILGYDGFNSIDGILLFIMLISYITYTIKKGGCCEEMGENNG
SIVKSVLFTILGLLAVIVGSSLFVSGAKDIALFLGISDKIIGFTLVAFGTSLPELVVSITAVKRKLGDMVIGNIIGSNIA
NIGGALALASIISPLPKVPFEMTVNLLLTSLMVLFMSKHILEFIKKNKDKIHNKKDNNDNETIYSKINRIDGTILILIYL
GFILFISNIL

Sequences:

>Translated_330_residues
MVEILFSVFILLLGLALLNYGSDWFVVGSSKVAKHLNVSNFVIGATVVAFGTSLPEIITSVYASYIGSTGIAVGNSLGSN
IANVGLILGLSALIAPIYIRKENILKNGYIYLLFTIIAFILGYDGFNSIDGILLFIMLISYITYTIKKGGCCEEMGENNG
SIVKSVLFTILGLLAVIVGSSLFVSGAKDIALFLGISDKIIGFTLVAFGTSLPELVVSITAVKRKLGDMVIGNIIGSNIA
NIGGALALASIISPLPKVPFEMTVNLLLTSLMVLFMSKHILEFIKKNKDKIHNKKDNNDNETIYSKINRIDGTILILIYL
GFILFISNIL
>Mature_330_residues
MVEILFSVFILLLGLALLNYGSDWFVVGSSKVAKHLNVSNFVIGATVVAFGTSLPEIITSVYASYIGSTGIAVGNSLGSN
IANVGLILGLSALIAPIYIRKENILKNGYIYLLFTIIAFILGYDGFNSIDGILLFIMLISYITYTIKKGGCCEEMGENNG
SIVKSVLFTILGLLAVIVGSSLFVSGAKDIALFLGISDKIIGFTLVAFGTSLPELVVSITAVKRKLGDMVIGNIIGSNIA
NIGGALALASIISPLPKVPFEMTVNLLLTSLMVLFMSKHILEFIKKNKDKIHNKKDNNDNETIYSKINRIDGTILILIYL
GFILFISNIL

Specific function: Unknown

COG id: COG0530

COG function: function code P; Ca2+/Na+ antiporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium/potassium/calcium exchanger family [H]

Homologues:

Organism=Homo sapiens, GI4759128, Length=101, Percent_Identity=37.6237623762376, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1789587, Length=248, Percent_Identity=33.8709677419355, Blast_Score=105, Evalue=5e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004481
- InterPro:   IPR004837 [H]

Pfam domain/function: PF01699 Na_Ca_ex [H]

EC number: NA

Molecular weight: Translated: 35459; Mature: 35459

Theoretical pI: Translated: 8.90; Mature: 8.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVEILFSVFILLLGLALLNYGSDWFVVGSSKVAKHLNVSNFVIGATVVAFGTSLPEIITS
CHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHH
VYASYIGSTGIAVGNSLGSNIANVGLILGLSALIAPIYIRKENILKNGYIYLLFTIIAFI
HHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
LGYDGFNSIDGILLFIMLISYITYTIKKGGCCEEMGENNGSIVKSVLFTILGLLAVIVGS
HCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHCC
SLFVSGAKDIALFLGISDKIIGFTLVAFGTSLPELVVSITAVKRKLGDMVIGNIIGSNIA
HHHHCCCHHHEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NIGGALALASIISPLPKVPFEMTVNLLLTSLMVLFMSKHILEFIKKNKDKIHNKKDNNDN
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCH
ETIYSKINRIDGTILILIYLGFILFISNIL
HHHHHHHHHCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVEILFSVFILLLGLALLNYGSDWFVVGSSKVAKHLNVSNFVIGATVVAFGTSLPEIITS
CHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHH
VYASYIGSTGIAVGNSLGSNIANVGLILGLSALIAPIYIRKENILKNGYIYLLFTIIAFI
HHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
LGYDGFNSIDGILLFIMLISYITYTIKKGGCCEEMGENNGSIVKSVLFTILGLLAVIVGS
HCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHCC
SLFVSGAKDIALFLGISDKIIGFTLVAFGTSLPELVVSITAVKRKLGDMVIGNIIGSNIA
HHHHCCCHHHEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NIGGALALASIISPLPKVPFEMTVNLLLTSLMVLFMSKHILEFIKKNKDKIHNKKDNNDN
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCH
ETIYSKINRIDGTILILIYLGFILFISNIL
HHHHHHHHHCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; Ca (II) [Cytoplasm] [C]

Specific reaction: Na (I) [Periplasm] + Ca (II) [Cytoplasm] = Na (I) [Cytoplasm] + Ca (II) [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]