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The map label for this gene is iscS [C]

Identifier: 150401111

GI number: 150401111

Start: 699023

End: 700180

Strand: Reverse

Name: iscS [C]

Synonym: Maeo_0681

Alternate gene names: 150401111

Gene position: 700180-699023 (Counterclockwise)

Preceding gene: 150401117

Following gene: 150401110

Centisome position: 44.61

GC content: 32.99

Gene sequence:

>1158_bases
ATGGACGAATTAAATATAAATTTTGACAAATATAAAAATATTAGGCGAACGATGGGACGAGAATTAATAGATTTAAATCC
AATACAAAGAGGAGGGGAGCTCCCAGTAGAATCAAAAAAAGCAATATATGAATATTGGGATGGATACAGTGTATGTGATT
ACTGTGGTGGAAGGTTGGATAAAGTAGAAACACCTCCAATTTGCGAATATTTGCATGATGTATCCAAATTTTTAGGAATG
GATTTTACTCGTCCGACGCATGGAGCAAGGGAAAGTAAATTTATAGTTATGCACTCTGTATGTAATGAAGGAGATTTCGT
AGTTCTTGATGGAAATGCACATTATACTTCTTTTGTAGCATTGGAAAGGGCAAAATTAAATAGTGAAATAGTTGAGCATG
ATGGTTATCCTACATTTAGAGTTAATCCCGAGAAATATGCGGAAGTTATTGATAATTTGGAGGATAAAAATAAACCAATA
GGATTAATATTATTAACTCATGTAGATGGAAATTATGGAAATCTTGCAGATGCTGAAAAAGTTGGAAAAATAGCAAAACA
AAAAGGATACCCATTTTTATTAAATTGTGCCTATTCTGTGGGAAGATTGCCAGTAAATGGAAAAAAACTAAATGCAGACT
TTTTGGCAATATCTGGACATAAAAGCATGGCTTCAGCCAGTCCTTGCGGTTTGGTATCTATAAAGGGAGAATATGCTGAT
AAAGTATTTAGAACATCAAAAACCCATCCAGTAAAAGAAATTGAAATGTTAGGTTGCACCAGTAGGGGAGCTCCACTTAT
TTCACTTATGGCAAGTTTCTCACATGTTGCCGAGAGAGTTAAAAACTGGGATAATGAAGTTAAAAAAACACGGTTTGTAG
TTGATGAATTAGAAAAAATAGGATTTAATCAACTGGGCATAAAACCAAAACAACATGATTTAATTAAATTTGAAACTCCA
ATATTGGACGAAATAGCACAGAAGGATAAAAGAAGAGGTTATTTCTTTTACGAGGAATTGAAAAAGAGGGGAATTGGAGG
CATAAAAAGAGGAACTACAAAAGAAATAAAAATGAGTGTTTATGGTTTATCGTGGGAACAAGTGCGTTATGTTGTAGATA
ACATTAAAGAAATTGTTGAACAGGGAAATAATATTTAA

Upstream 100 bases:

>100_bases
GCGTATTAATAGAATATAGTCTTATTTGCATAAACAGGGTGAAACAGTTCGAAGATTGACTATATATATTTTATATGACA
ACTTAAATATTGGTGCTAAT

Downstream 100 bases:

>100_bases
AAAATATATTAAAACGATAATCTTGATTATCGTATTTTTTTTATTTTGGGGACATCGTTAAATATTTAATAAATGTTGAA
TTACACGGAGCTCCCAAACC

Product: Sep-tRNA:Cys-tRNA synthetase

Products: NA

Alternate protein names: Sep-tRNA:Cys-tRNA synthase; SepCysS

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MDELNINFDKYKNIRRTMGRELIDLNPIQRGGELPVESKKAIYEYWDGYSVCDYCGGRLDKVETPPICEYLHDVSKFLGM
DFTRPTHGARESKFIVMHSVCNEGDFVVLDGNAHYTSFVALERAKLNSEIVEHDGYPTFRVNPEKYAEVIDNLEDKNKPI
GLILLTHVDGNYGNLADAEKVGKIAKQKGYPFLLNCAYSVGRLPVNGKKLNADFLAISGHKSMASASPCGLVSIKGEYAD
KVFRTSKTHPVKEIEMLGCTSRGAPLISLMASFSHVAERVKNWDNEVKKTRFVVDELEKIGFNQLGIKPKQHDLIKFETP
ILDEIAQKDKRRGYFFYEELKKRGIGGIKRGTTKEIKMSVYGLSWEQVRYVVDNIKEIVEQGNNI

Sequences:

>Translated_385_residues
MDELNINFDKYKNIRRTMGRELIDLNPIQRGGELPVESKKAIYEYWDGYSVCDYCGGRLDKVETPPICEYLHDVSKFLGM
DFTRPTHGARESKFIVMHSVCNEGDFVVLDGNAHYTSFVALERAKLNSEIVEHDGYPTFRVNPEKYAEVIDNLEDKNKPI
GLILLTHVDGNYGNLADAEKVGKIAKQKGYPFLLNCAYSVGRLPVNGKKLNADFLAISGHKSMASASPCGLVSIKGEYAD
KVFRTSKTHPVKEIEMLGCTSRGAPLISLMASFSHVAERVKNWDNEVKKTRFVVDELEKIGFNQLGIKPKQHDLIKFETP
ILDEIAQKDKRRGYFFYEELKKRGIGGIKRGTTKEIKMSVYGLSWEQVRYVVDNIKEIVEQGNNI
>Mature_385_residues
MDELNINFDKYKNIRRTMGRELIDLNPIQRGGELPVESKKAIYEYWDGYSVCDYCGGRLDKVETPPICEYLHDVSKFLGM
DFTRPTHGARESKFIVMHSVCNEGDFVVLDGNAHYTSFVALERAKLNSEIVEHDGYPTFRVNPEKYAEVIDNLEDKNKPI
GLILLTHVDGNYGNLADAEKVGKIAKQKGYPFLLNCAYSVGRLPVNGKKLNADFLAISGHKSMASASPCGLVSIKGEYAD
KVFRTSKTHPVKEIEMLGCTSRGAPLISLMASFSHVAERVKNWDNEVKKTRFVVDELEKIGFNQLGIKPKQHDLIKFETP
ILDEIAQKDKRRGYFFYEELKKRGIGGIKRGTTKEIKMSVYGLSWEQVRYVVDNIKEIVEQGNNI

Specific function: Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L-cysteinyl-tRNA(Cys) (Cys-tRNA(Cys))

COG id: COG1103

COG function: function code R; Archaea-specific pyridoxal phosphate-dependent enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SepCysS family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SPSS_META3 (A6UUU3)

Other databases:

- EMBL:   CP000743
- RefSeq:   YP_001324877.1
- ProteinModelPortal:   A6UUU3
- SMR:   A6UUU3
- STRING:   A6UUU3
- GeneID:   5326269
- GenomeReviews:   CP000743_GR
- KEGG:   mae:Maeo_0681
- eggNOG:   arNOG04793
- HOGENOM:   HBG539014
- OMA:   HKSMAAS
- ProtClustDB:   PRK09331
- BioCyc:   MAEO419665:MAEO_0681-MONOMER
- GO:   GO:0006412
- HAMAP:   MF_01675
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR013375
- InterPro:   IPR008829
- Gene3D:   G3DSA:3.40.640.10
- TIGRFAMs:   TIGR02539

Pfam domain/function: PF05889 SLA_LP_auto_ag; SSF53383 PyrdxlP-dep_Trfase_major

EC number: =2.5.1.73

Molecular weight: Translated: 43616; Mature: 43616

Theoretical pI: Translated: 8.05; Mature: 8.05

Prosite motif: NA

Important sites: BINDING 90-90 BINDING 114-114 BINDING 115-115 BINDING 195-195 BINDING 279-279 BINDING 288-288

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDELNINFDKYKNIRRTMGRELIDLNPIQRGGELPVESKKAIYEYWDGYSVCDYCGGRLD
CCCCCCCHHHHHHHHHHHCCHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHCCCCCC
KVETPPICEYLHDVSKFLGMDFTRPTHGARESKFIVMHSVCNEGDFVVLDGNAHYTSFVA
CCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCEEEECCCCCCHHHHH
LERAKLNSEIVEHDGYPTFRVNPEKYAEVIDNLEDKNKPIGLILLTHVDGNYGNLADAEK
HHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCHHH
VGKIAKQKGYPFLLNCAYSVGRLPVNGKKLNADFLAISGHKSMASASPCGLVSIKGEYAD
HHHHHHHCCCCEEEEEHHHHCCCCCCCCEECCEEEEEECCCCCCCCCCCCEEEECCHHHH
KVFRTSKTHPVKEIEMLGCTSRGAPLISLMASFSHVAERVKNWDNEVKKTRFVVDELEKI
HHHHCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GFNQLGIKPKQHDLIKFETPILDEIAQKDKRRGYFFYEELKKRGIGGIKRGTTKEIKMSV
CCHHCCCCCCCCCCEEECCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCEEEEEE
YGLSWEQVRYVVDNIKEIVEQGNNI
ECCCHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MDELNINFDKYKNIRRTMGRELIDLNPIQRGGELPVESKKAIYEYWDGYSVCDYCGGRLD
CCCCCCCHHHHHHHHHHHCCHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHCCCCCC
KVETPPICEYLHDVSKFLGMDFTRPTHGARESKFIVMHSVCNEGDFVVLDGNAHYTSFVA
CCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCEEEECCCCCCHHHHH
LERAKLNSEIVEHDGYPTFRVNPEKYAEVIDNLEDKNKPIGLILLTHVDGNYGNLADAEK
HHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCHHH
VGKIAKQKGYPFLLNCAYSVGRLPVNGKKLNADFLAISGHKSMASASPCGLVSIKGEYAD
HHHHHHHCCCCEEEEEHHHHCCCCCCCCEECCEEEEEECCCCCCCCCCCCEEEECCHHHH
KVFRTSKTHPVKEIEMLGCTSRGAPLISLMASFSHVAERVKNWDNEVKKTRFVVDELEKI
HHHHCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GFNQLGIKPKQHDLIKFETPILDEIAQKDKRRGYFFYEELKKRGIGGIKRGTTKEIKMSV
CCHHCCCCCCCCCCEEECCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCEEEEEE
YGLSWEQVRYVVDNIKEIVEQGNNI
ECCCHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA