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The map label for this gene is eIF1A

Identifier: 150401026

GI number: 150401026

Start: 610708

End: 611025

Strand: Reverse

Name: eIF1A

Synonym: Maeo_0595

Alternate gene names: 150401026

Gene position: 611025-610708 (Counterclockwise)

Preceding gene: 150401033

Following gene: 150401025

Centisome position: 38.93

GC content: 38.05

Gene sequence:

>318_bases
TTGCAGAAGAAGCCAATGGCGCCACAGCAACCCACAAGAGTTAGAACTCCAAGGGAAGAAAACAATGAAATATTGGGAAT
AATAGAGCAAATGCTTGGAGCAAGTAGAGTAAGAGTAAGATGTATGGACGGACATACAAGAATGGGTAGAATCCCAGGAA
AATTAAAAAGAAAAATATGGGTCCGAGAAGGGGATATCGTAATAGTAGTGCCTTGGGAGGTTCAATCCGACCAGAAATGT
GATATTATTTGGAGATATACAAAAGGACAGGTAAGCTGGTTATCTAAAAAAGGATATTTAAAACAAGCATATGATTAA

Upstream 100 bases:

>100_bases
TGCAACAAGTTTTTGAACATATTATATAGAATAATAAAATAAACTAATTAGCTCATATTAATATAACAATGAATATAAAA
TAAAAAAAATAGGTGATAAA

Downstream 100 bases:

>100_bases
AATGGGGGATATTATGGAAAACCCCAATAAACAGGAAAAACGACTGGATAACGAATACCAGAAAAAAATAATTGAAAGAA
AAAAGAAATTTTTGGAAGAT

Product: translation initiation factor IF-1A

Products: NA

Alternate protein names: aIF-1A

Number of amino acids: Translated: 105; Mature: 105

Protein sequence:

>105_residues
MQKKPMAPQQPTRVRTPREENNEILGIIEQMLGASRVRVRCMDGHTRMGRIPGKLKRKIWVREGDIVIVVPWEVQSDQKC
DIIWRYTKGQVSWLSKKGYLKQAYD

Sequences:

>Translated_105_residues
MQKKPMAPQQPTRVRTPREENNEILGIIEQMLGASRVRVRCMDGHTRMGRIPGKLKRKIWVREGDIVIVVPWEVQSDQKC
DIIWRYTKGQVSWLSKKGYLKQAYD
>Mature_105_residues
MQKKPMAPQQPTRVRTPREENNEILGIIEQMLGASRVRVRCMDGHTRMGRIPGKLKRKIWVREGDIVIVVPWEVQSDQKC
DIIWRYTKGQVSWLSKKGYLKQAYD

Specific function: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits

COG id: COG0361

COG function: function code J; Translation initiation factor 1 (IF-1)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1-like domain

Homologues:

Organism=Saccharomyces cerevisiae, GI6323916, Length=90, Percent_Identity=38.8888888888889, Blast_Score=69, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IF1A_META3 (A6UUK8)

Other databases:

- EMBL:   CP000743
- RefSeq:   YP_001324792.1
- ProteinModelPortal:   A6UUK8
- SMR:   A6UUK8
- STRING:   A6UUK8
- GeneID:   5327648
- GenomeReviews:   CP000743_GR
- KEGG:   mae:Maeo_0595
- eggNOG:   arNOG11452
- HOGENOM:   HBG521228
- OMA:   IWIREGD
- ProtClustDB:   PRK04012
- BioCyc:   MAEO419665:MAEO_0595-MONOMER
- HAMAP:   MF_00216
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR006196
- InterPro:   IPR001253
- InterPro:   IPR018104
- Gene3D:   G3DSA:2.40.50.140
- PANTHER:   PTHR21668
- ProDom:   PD005579
- SMART:   SM00652
- TIGRFAMs:   TIGR00523

Pfam domain/function: PF01176 eIF-1a; SSF50249 Nucleic_acid_OB

EC number: NA

Molecular weight: Translated: 12337; Mature: 12337

Theoretical pI: Translated: 10.70; Mature: 10.70

Prosite motif: PS01262 IF1A; PS50832 S1_IF1_TYPE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKKPMAPQQPTRVRTPREENNEILGIIEQMLGASRVRVRCMDGHTRMGRIPGKLKRKIW
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCEEEE
VREGDIVIVVPWEVQSDQKCDIIWRYTKGQVSWLSKKGYLKQAYD
EECCCEEEEECCCCCCCCCCEEEEEECCCCEEEECCCCCCCCCCC
>Mature Secondary Structure
MQKKPMAPQQPTRVRTPREENNEILGIIEQMLGASRVRVRCMDGHTRMGRIPGKLKRKIW
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCEEEE
VREGDIVIVVPWEVQSDQKCDIIWRYTKGQVSWLSKKGYLKQAYD
EECCCEEEEECCCCCCCCCCEEEEEECCCCEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA