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The map label for this gene is rio1 [H]

Identifier: 150401025

GI number: 150401025

Start: 609882

End: 610694

Strand: Reverse

Name: rio1 [H]

Synonym: Maeo_0594

Alternate gene names: 150401025

Gene position: 610694-609882 (Counterclockwise)

Preceding gene: 150401026

Following gene: 150401024

Centisome position: 38.91

GC content: 30.01

Gene sequence:

>813_bases
ATGGAAAACCCCAATAAACAGGAAAAACGACTGGATAACGAATACCAGAAAAAAATAATTGAAAGAAAAAAGAAATTTTT
GGAAGATTTCAAAACTGAAAATAGTGTATTTGATAAAAAAACCCAGTTGGCACTGTTCGGACTTTTAAATGCAAATCATG
TTGATGAATATCTTGGAATAATTAATTCTGGAAAGGAATCAATAGTATTTTTAGCAGTTAAGGATAATAAATATTGTGCT
GTAAAAGTTTATCGAGTTTCAACCTGTGATTTTAAAACTATGTGGAAATATATCCAAGGAGACCCACGATTTCATTTAAG
AAAGAGCTCCACCAGACAGATAATACATGCCTGGGTAGATAAAGAATATAGAAATCTATTAAGAGCAAATAAATATGTAA
ATAGCTCAAAAGCAATATTAAAACGGGACAATGTAATGTTAATGGAATTGGTGGGCGATGGAGATATTCCAGCCCCTCGA
TTAAAAGATTACAATGGAGATATAGATTACTCCAAATTATATAATACCATTGTGGAAGATTTAAAAATATTATACAATGA
TGCCCAAATTGTTCATGGGGATTTATCGGAGTATAATATATTGATTAAAGATAATGAGCCTGTTTATATTGACTTTTCCC
AGGGTGTTGTAATACAGCATCCCCTTTCAAAATCTTTATTGATTAGAGATATAAAAAATGTTTGTAATTACTTTATTAAA
AAAGGAGTTTCCTGCAATTATAAAGAATTATTTAAATATATAACTGGGGAGGAGCTCCGACCAATTGAAGAAGAATTAGC
AATAGGATATTAA

Upstream 100 bases:

>100_bases
CAGAAATGTGATATTATTTGGAGATATACAAAAGGACAGGTAAGCTGGTTATCTAAAAAAGGATATTTAAAACAAGCATA
TGATTAAAATGGGGGATATT

Downstream 100 bases:

>100_bases
TTTTTATATTAATTTTTATATATTTTTTATTAATTTATAACTCAGTATAATATAATACAAATATTTTTTTAAAATAAAAA
ATTTTAATAATATAGTTTTA

Product: non-specific serine/threonine protein kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MENPNKQEKRLDNEYQKKIIERKKKFLEDFKTENSVFDKKTQLALFGLLNANHVDEYLGIINSGKESIVFLAVKDNKYCA
VKVYRVSTCDFKTMWKYIQGDPRFHLRKSSTRQIIHAWVDKEYRNLLRANKYVNSSKAILKRDNVMLMELVGDGDIPAPR
LKDYNGDIDYSKLYNTIVEDLKILYNDAQIVHGDLSEYNILIKDNEPVYIDFSQGVVIQHPLSKSLLIRDIKNVCNYFIK
KGVSCNYKELFKYITGEELRPIEEELAIGY

Sequences:

>Translated_270_residues
MENPNKQEKRLDNEYQKKIIERKKKFLEDFKTENSVFDKKTQLALFGLLNANHVDEYLGIINSGKESIVFLAVKDNKYCA
VKVYRVSTCDFKTMWKYIQGDPRFHLRKSSTRQIIHAWVDKEYRNLLRANKYVNSSKAILKRDNVMLMELVGDGDIPAPR
LKDYNGDIDYSKLYNTIVEDLKILYNDAQIVHGDLSEYNILIKDNEPVYIDFSQGVVIQHPLSKSLLIRDIKNVCNYFIK
KGVSCNYKELFKYITGEELRPIEEELAIGY
>Mature_270_residues
MENPNKQEKRLDNEYQKKIIERKKKFLEDFKTENSVFDKKTQLALFGLLNANHVDEYLGIINSGKESIVFLAVKDNKYCA
VKVYRVSTCDFKTMWKYIQGDPRFHLRKSSTRQIIHAWVDKEYRNLLRANKYVNSSKAILKRDNVMLMELVGDGDIPAPR
LKDYNGDIDYSKLYNTIVEDLKILYNDAQIVHGDLSEYNILIKDNEPVYIDFSQGVVIQHPLSKSLLIRDIKNVCNYFIK
KGVSCNYKELFKYITGEELRPIEEELAIGY

Specific function: Unknown

COG id: COG1718

COG function: function code TD; Serine/threonine protein kinase involved in cell cycle control

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI23510356, Length=233, Percent_Identity=33.9055793991416, Blast_Score=134, Evalue=7e-32,
Organism=Homo sapiens, GI22325377, Length=257, Percent_Identity=33.0739299610895, Blast_Score=132, Evalue=3e-31,
Organism=Homo sapiens, GI23510358, Length=145, Percent_Identity=33.7931034482759, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI115532073, Length=262, Percent_Identity=33.969465648855, Blast_Score=128, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI17556977, Length=237, Percent_Identity=32.9113924050633, Blast_Score=125, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI71989043, Length=171, Percent_Identity=33.3333333333333, Blast_Score=79, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6324693, Length=259, Percent_Identity=31.2741312741313, Blast_Score=115, Evalue=6e-27,
Organism=Drosophila melanogaster, GI24662811, Length=238, Percent_Identity=37.8151260504202, Blast_Score=144, Evalue=6e-35,
Organism=Drosophila melanogaster, GI21356879, Length=238, Percent_Identity=37.8151260504202, Blast_Score=144, Evalue=6e-35,
Organism=Drosophila melanogaster, GI19920700, Length=257, Percent_Identity=33.0739299610895, Blast_Score=132, Evalue=3e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR018934
- InterPro:   IPR000687
- InterPro:   IPR018935
- InterPro:   IPR008266 [H]

Pfam domain/function: PF01163 RIO1 [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 31614; Mature: 31614

Theoretical pI: Translated: 8.73; Mature: 8.73

Prosite motif: PS00109 PROTEIN_KINASE_TYR ; PS50011 PROTEIN_KINASE_DOM ; PS01245 RIO1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENPNKQEKRLDNEYQKKIIERKKKFLEDFKTENSVFDKKTQLALFGLLNANHVDEYLGI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHH
INSGKESIVFLAVKDNKYCAVKVYRVSTCDFKTMWKYIQGDPRFHLRKSSTRQIIHAWVD
HCCCCCEEEEEEEECCCEEEEEEEEECCCCHHHHHHHHCCCCCEEEECHHHHHHHHHHHH
KEYRNLLRANKYVNSSKAILKRDNVMLMELVGDGDIPAPRLKDYNGDIDYSKLYNTIVED
HHHHHHHHHHHHCCCCHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHH
LKILYNDAQIVHGDLSEYNILIKDNEPVYIDFSQGVVIQHPLSKSLLIRDIKNVCNYFIK
HHHHHCCCCEEECCCCCEEEEEECCCEEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHH
KGVSCNYKELFKYITGEELRPIEEELAIGY
CCCCCCHHHHHHHHCCCCCCCCHHHHCCCC
>Mature Secondary Structure
MENPNKQEKRLDNEYQKKIIERKKKFLEDFKTENSVFDKKTQLALFGLLNANHVDEYLGI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHH
INSGKESIVFLAVKDNKYCAVKVYRVSTCDFKTMWKYIQGDPRFHLRKSSTRQIIHAWVD
HCCCCCEEEEEEEECCCEEEEEEEEECCCCHHHHHHHHCCCCCEEEECHHHHHHHHHHHH
KEYRNLLRANKYVNSSKAILKRDNVMLMELVGDGDIPAPRLKDYNGDIDYSKLYNTIVED
HHHHHHHHHHHHCCCCHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHH
LKILYNDAQIVHGDLSEYNILIKDNEPVYIDFSQGVVIQHPLSKSLLIRDIKNVCNYFIK
HHHHHCCCCEEECCCCCEEEEEECCCEEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHH
KGVSCNYKELFKYITGEELRPIEEELAIGY
CCCCCCHHHHHHHHCCCCCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]