| Definition | Methanococcus aeolicus Nankai-3, complete genome. |
|---|---|
| Accession | NC_009635 |
| Length | 1,569,500 |
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The map label for this gene is ugd [C]
Identifier: 150400846
GI number: 150400846
Start: 431821
End: 434541
Strand: Direct
Name: ugd [C]
Synonym: Maeo_0414
Alternate gene names: 150400846
Gene position: 431821-434541 (Clockwise)
Preceding gene: 150400845
Following gene: 150400847
Centisome position: 27.51
GC content: 28.92
Gene sequence:
>2721_bases ATGAAAATTTCAGTAATAGGAACAGGATATGTTGGCTTAATTCAAAGTGTAGGTTTGGCAGAGTTTGGATTTGATGTAGT AGGTATAGATATAGACGAAACTAAGGTAAAACGACTTAATGAGGGTAAATGTCCATTGTATGAAGATGGTTTGGAGGAGC TCCTAACAAATAATATAAATAAAAACTTAAAATTTACAACCTCATACCAGGAGATAAAAGATAGTGATATTATTTTTCTA TGTGTGGGGACCCCCCAAGATGAAAAAGGAAATGCAGATTTAAGATTTATTTACTCCGCCACAGAATCGATTAAAAAACA GCTAACAAAGGACAGTTATAAAGTTATAGTTCTAAAATCCACAGTACCAATTGGAACAAATAGAAAAATTAAGGAATCGT TAAAGGATTATATCGTTGATGTTGTTTCAAATCCTGAATTTTTAAGGGAGGGAATTGCAGTAGATGATTTCTTTAATCCT GAAAGAATTGTATTGGGATTTGAAAATTTAGAAAATAAAAAACCAATTGAAGCGATGAAAAAAATATATGGGGAATTTGA AGATAAGGGAGCTCCCATAATTATCACAGATTGGGAAAGTGCTGAAATGATAAAATATGCTTCCAATGCCTTTTTAGCTA CAAAAATTTCCTTTGCAAATGAATTATCAAAATTATCCGATGAAGTTGGTGCAGATATAAAAACCATAAGTGAGGCCATG GGAATCGATAAAAGGATTGGAAACAAGTTTTTAAACGCTGGAATAGGCTATGGCGGAAGCTGCTTCCATCCTGATGAAAT ACTATTTGTGGATTTTGGAGATGGATTAGAATGTATGGCATTTAAAGAACTATTTGACGAGCTCAGTAGAGACAATAATA GAAGTGTGAAAATATTATCCATCAATAAAAATTTAAAATTGGATTTAGCAAATCTAAAATTAATAACAAAAAGAGATTAC TCTGATGATTTAATTGTTTTAAAAACGACAATGGGAAGAGAAATAAAAATAACAAAAGACCATCCTGTTGTTGTGTTGAA TGGAGATAAACTACATGTTAAATTAGCGGAAAATATTAAAGAAGGGGATGAAATAGCACTACCTAAGGGGGAATTTAATA GTAATAGTAATATTAATAATATAATTACAATCGATATATTGGAAGAAATAAAAAATACCCCATTAATTGAAAAAACATAT TTAAATAATAAAAATATGGTGTTAAATGAATTTGAGAATATAAGAGCTCATCTATCAAACAAATATATTCACGATATAAA GAAGAATGGAACCGTAAGAGCAAAGGATATGTTACCAATAAGAAGCATATTAAATAAATATAATTATAATTCAAATAGGC TATTCACCGTTAGAAGCAAATCTACAACAATTCCATCAGTTATAAAAATAGACGGCGATTTTGCTAGATTAATAGGATAT TATTTAGCAGAAGGTTGGATTTCAGAGGATGGTAAAAAAAATGGTGCTATTAGAAAAAGAATTAGTTTTTCATTCGGAGC TCATGAGGAAGAATATATCAACGATGTTAAAAATATATTGAATAAATTGGATATAAATTATATCGAAAAAATTAGAAATG GTTCCCATTCCATAATAATATCTTCAAAATTGTTGGCATATATCTTCGAAGAGGCATTAAAATGTGGAAATAATTGTTAT AACAAGCAAATACCGCCACAAATATTTAATTCACCATCAGATATTAAATGGGAATTCTTAAAAGGTATTTTAAGGGGAGA TGGAGGTATTGTTAAATTAAATAATAACAAGAACCTAAACATTGAATATGGAACAGTCAGTAAAAAATTGGCAAATTCTT TGATGATATTATTACAATCGTTGGGCATAATCACATCATTAAAAAGATGCTACAATAACAAAAGCACAACATTAACCTAT ATTATAAGGATAAACGGATTAAACCAGGTTAAAAAAATCGGAGAATTATTTGGGGATAAATGGAACAATTACAAAGAAAT TGCAGATAATTATGAAAGAAATATAAAACCTATTGGTTATAAAAAATTTGATAACTATGCATCATTAAAGGTTAAATCCG TTGAAAGAGAATATTATGGCGGAGAAGTATATAGTGTAGAAACAGATAATAATTTGTTAATATCTTCTTATGGATTGTTA ATTCATAACTGCTTCCCAAAAGATGTTAGGGCACTTATAAATCAGTTTGAAAACCACAATATCTCCCCAAAATTGATTAA AGCCACAGATGAAGTAAATGATGAACAAATAAAATGGTTCTTCGATAAAATTAAAAATTATTATAACAACGATATTAATC AAAAAACCTTTGCAGTGTTGGGATTGGCATTTAAGCCAAATACTGATGATTTAAGAGAAAGCAGAGGTATAAAATTAATT GATTTGCTGTTAGAAGATGGTGCAATAGTTAAGGGCTTCGATTATGTTGAGAAAGCGAGAGAAAATACCATTAATAAATA TAAGTTGGATAAATCAAAAGCATTTTATGGATATAATTTATATGTATTAGATGATTTATACGAAACTGTAAAAGATGTTG ATGCCATTATAATAACTACGGAATATGATTTCAATGATGAAGATTGGGAAAAAATAAACAAATTAGTTAAGGATAAAGTT GTATTTGATGGTAGAAATATTCTCGATATGGACAAAATAAAGAAATTGGGATTTGAGTATTATGGGGTAGGTAGGAAATG A
Upstream 100 bases:
>100_bases TGACAGTGAAACTCAAAAAATATATCATGGCATTAATAACGATATTCTTAGCTTAAAATTAAATATTGAAGTTAAAAAAT CATATATGTGGGGTTAATTT
Downstream 100 bases:
>100_bases AATATAAAAATATTTTAATAACTGGAAGTGCGGGATTTATTGGATTTCATTTAAGCAAATATTTATTGGAAAATTATAAT AATGTCCAAGTCATTGGGAT
Product: UDP-glucose 6-dehydrogenase
Products: UDP-glucuronate; NADH; H+
Alternate protein names: NA
Number of amino acids: Translated: 906; Mature: 906
Protein sequence:
>906_residues MKISVIGTGYVGLIQSVGLAEFGFDVVGIDIDETKVKRLNEGKCPLYEDGLEELLTNNINKNLKFTTSYQEIKDSDIIFL CVGTPQDEKGNADLRFIYSATESIKKQLTKDSYKVIVLKSTVPIGTNRKIKESLKDYIVDVVSNPEFLREGIAVDDFFNP ERIVLGFENLENKKPIEAMKKIYGEFEDKGAPIIITDWESAEMIKYASNAFLATKISFANELSKLSDEVGADIKTISEAM GIDKRIGNKFLNAGIGYGGSCFHPDEILFVDFGDGLECMAFKELFDELSRDNNRSVKILSINKNLKLDLANLKLITKRDY SDDLIVLKTTMGREIKITKDHPVVVLNGDKLHVKLAENIKEGDEIALPKGEFNSNSNINNIITIDILEEIKNTPLIEKTY LNNKNMVLNEFENIRAHLSNKYIHDIKKNGTVRAKDMLPIRSILNKYNYNSNRLFTVRSKSTTIPSVIKIDGDFARLIGY YLAEGWISEDGKKNGAIRKRISFSFGAHEEEYINDVKNILNKLDINYIEKIRNGSHSIIISSKLLAYIFEEALKCGNNCY NKQIPPQIFNSPSDIKWEFLKGILRGDGGIVKLNNNKNLNIEYGTVSKKLANSLMILLQSLGIITSLKRCYNNKSTTLTY IIRINGLNQVKKIGELFGDKWNNYKEIADNYERNIKPIGYKKFDNYASLKVKSVEREYYGGEVYSVETDNNLLISSYGLL IHNCFPKDVRALINQFENHNISPKLIKATDEVNDEQIKWFFDKIKNYYNNDINQKTFAVLGLAFKPNTDDLRESRGIKLI DLLLEDGAIVKGFDYVEKARENTINKYKLDKSKAFYGYNLYVLDDLYETVKDVDAIIITTEYDFNDEDWEKINKLVKDKV VFDGRNILDMDKIKKLGFEYYGVGRK
Sequences:
>Translated_906_residues MKISVIGTGYVGLIQSVGLAEFGFDVVGIDIDETKVKRLNEGKCPLYEDGLEELLTNNINKNLKFTTSYQEIKDSDIIFL CVGTPQDEKGNADLRFIYSATESIKKQLTKDSYKVIVLKSTVPIGTNRKIKESLKDYIVDVVSNPEFLREGIAVDDFFNP ERIVLGFENLENKKPIEAMKKIYGEFEDKGAPIIITDWESAEMIKYASNAFLATKISFANELSKLSDEVGADIKTISEAM GIDKRIGNKFLNAGIGYGGSCFHPDEILFVDFGDGLECMAFKELFDELSRDNNRSVKILSINKNLKLDLANLKLITKRDY SDDLIVLKTTMGREIKITKDHPVVVLNGDKLHVKLAENIKEGDEIALPKGEFNSNSNINNIITIDILEEIKNTPLIEKTY LNNKNMVLNEFENIRAHLSNKYIHDIKKNGTVRAKDMLPIRSILNKYNYNSNRLFTVRSKSTTIPSVIKIDGDFARLIGY YLAEGWISEDGKKNGAIRKRISFSFGAHEEEYINDVKNILNKLDINYIEKIRNGSHSIIISSKLLAYIFEEALKCGNNCY NKQIPPQIFNSPSDIKWEFLKGILRGDGGIVKLNNNKNLNIEYGTVSKKLANSLMILLQSLGIITSLKRCYNNKSTTLTY IIRINGLNQVKKIGELFGDKWNNYKEIADNYERNIKPIGYKKFDNYASLKVKSVEREYYGGEVYSVETDNNLLISSYGLL IHNCFPKDVRALINQFENHNISPKLIKATDEVNDEQIKWFFDKIKNYYNNDINQKTFAVLGLAFKPNTDDLRESRGIKLI DLLLEDGAIVKGFDYVEKARENTINKYKLDKSKAFYGYNLYVLDDLYETVKDVDAIIITTEYDFNDEDWEKINKLVKDKV VFDGRNILDMDKIKKLGFEYYGVGRK >Mature_906_residues MKISVIGTGYVGLIQSVGLAEFGFDVVGIDIDETKVKRLNEGKCPLYEDGLEELLTNNINKNLKFTTSYQEIKDSDIIFL CVGTPQDEKGNADLRFIYSATESIKKQLTKDSYKVIVLKSTVPIGTNRKIKESLKDYIVDVVSNPEFLREGIAVDDFFNP ERIVLGFENLENKKPIEAMKKIYGEFEDKGAPIIITDWESAEMIKYASNAFLATKISFANELSKLSDEVGADIKTISEAM GIDKRIGNKFLNAGIGYGGSCFHPDEILFVDFGDGLECMAFKELFDELSRDNNRSVKILSINKNLKLDLANLKLITKRDY SDDLIVLKTTMGREIKITKDHPVVVLNGDKLHVKLAENIKEGDEIALPKGEFNSNSNINNIITIDILEEIKNTPLIEKTY LNNKNMVLNEFENIRAHLSNKYIHDIKKNGTVRAKDMLPIRSILNKYNYNSNRLFTVRSKSTTIPSVIKIDGDFARLIGY YLAEGWISEDGKKNGAIRKRISFSFGAHEEEYINDVKNILNKLDINYIEKIRNGSHSIIISSKLLAYIFEEALKCGNNCY NKQIPPQIFNSPSDIKWEFLKGILRGDGGIVKLNNNKNLNIEYGTVSKKLANSLMILLQSLGIITSLKRCYNNKSTTLTY IIRINGLNQVKKIGELFGDKWNNYKEIADNYERNIKPIGYKKFDNYASLKVKSVEREYYGGEVYSVETDNNLLISSYGLL IHNCFPKDVRALINQFENHNISPKLIKATDEVNDEQIKWFFDKIKNYYNNDINQKTFAVLGLAFKPNTDDLRESRGIKLI DLLLEDGAIVKGFDYVEKARENTINKYKLDKSKAFYGYNLYVLDDLYETVKDVDAIIITTEYDFNDEDWEKINKLVKDKV VFDGRNILDMDKIKKLGFEYYGVGRK
Specific function: Unknown
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 DOD-type homing endonuclease domain [H]
Homologues:
Organism=Homo sapiens, GI4507813, Length=291, Percent_Identity=35.3951890034364, Blast_Score=178, Evalue=2e-44, Organism=Homo sapiens, GI296040443, Length=278, Percent_Identity=31.294964028777, Blast_Score=134, Evalue=3e-31, Organism=Homo sapiens, GI296040438, Length=193, Percent_Identity=36.7875647668394, Blast_Score=132, Evalue=1e-30, Organism=Escherichia coli, GI1788340, Length=269, Percent_Identity=33.0855018587361, Blast_Score=135, Evalue=1e-32, Organism=Escherichia coli, GI48994968, Length=283, Percent_Identity=28.6219081272085, Blast_Score=101, Evalue=3e-22, Organism=Caenorhabditis elegans, GI17560350, Length=291, Percent_Identity=33.3333333333333, Blast_Score=158, Evalue=1e-38, Organism=Drosophila melanogaster, GI17136908, Length=279, Percent_Identity=37.9928315412186, Blast_Score=178, Evalue=1e-44,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR008927 - InterPro: IPR013328 - InterPro: IPR003586 - InterPro: IPR003587 - InterPro: IPR006142 - InterPro: IPR004042 - InterPro: IPR006141 - InterPro: IPR016040 - InterPro: IPR017476 - InterPro: IPR014027 - InterPro: IPR014026 - InterPro: IPR014028 - InterPro: IPR001732 [H]
Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]
EC number: 1.1.1.22
Molecular weight: Translated: 103349; Mature: 103349
Theoretical pI: Translated: 6.99; Mature: 6.99
Prosite motif: PS50817 INTEIN_N_TER ; PS50818 INTEIN_C_TER ; PS50819 INTEIN_ENDONUCLEASE
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.9 %Cys (Translated Protein) 1.1 %Met (Translated Protein) 2.0 %Cys+Met (Translated Protein) 0.9 %Cys (Mature Protein) 1.1 %Met (Mature Protein) 2.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKISVIGTGYVGLIQSVGLAEFGFDVVGIDIDETKVKRLNEGKCPLYEDGLEELLTNNIN CEEEEEECCHHHHHHHCCHHHCCCEEEEECCCHHHHHHCCCCCCCCHHHHHHHHHHCCCC KNLKFTTSYQEIKDSDIIFLCVGTPQDEKGNADLRFIYSATESIKKQLTKDSYKVIVLKS CCEEEEECHHHCCCCCEEEEEECCCCCCCCCCCEEEEEHHHHHHHHHHCCCCEEEEEEEE TVPIGTNRKIKESLKDYIVDVVSNPEFLREGIAVDDFFNPERIVLGFENLENKKPIEAMK CCCCCCCHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCEEEEEECCCCCCCHHHHHH KIYGEFEDKGAPIIITDWESAEMIKYASNAFLATKISFANELSKLSDEVGADIKTISEAM HHHCCCCCCCCCEEEECCCCHHHHHHHCCCEEEEHHHHHHHHHHHHHHHCCHHHHHHHHH GIDKRIGNKFLNAGIGYGGSCFHPDEILFVDFGDGLECMAFKELFDELSRDNNRSVKILS CCHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCEEEEEE INKNLKLDLANLKLITKRDYSDDLIVLKTTMGREIKITKDHPVVVLNGDKLHVKLAENIK ECCCCEEEEEEEEEEEECCCCCCEEEEEECCCCEEEEECCCCEEEEECCEEEEEEHHCCC EGDEIALPKGEFNSNSNINNIITIDILEEIKNTPLIEKTYLNNKNMVLNEFENIRAHLSN CCCCEECCCCCCCCCCCCCEEEEEEEHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHH KYIHDIKKNGTVRAKDMLPIRSILNKYNYNSNRLFTVRSKSTTIPSVIKIDGDFARLIGY HHHHHHHCCCCEEEHHCHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEECCHHHHHHHH YLAEGWISEDGKKNGAIRKRISFSFGAHEEEYINDVKNILNKLDINYIEKIRNGSHSIII HHHCCCCCCCCCCCCCHHEEEEECCCCCHHHHHHHHHHHHHHHCHHHHHHHCCCCCEEEE SSKLLAYIFEEALKCGNNCYNKQIPPQIFNSPSDIKWEFLKGILRGDGGIVKLNNNKNLN HHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCHHHHHHHHHCCCCCEEEECCCCEEE IEYGTVSKKLANSLMILLQSLGIITSLKRCYNNKSTTLTYIIRINGLNQVKKIGELFGDK EEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCHHHHHHHHHHHCCC WNNYKEIADNYERNIKPIGYKKFDNYASLKVKSVEREYYGGEVYSVETDNNLLISSYGLL CCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEHHHHHCCCEEEEEECCCCEEEEECCCH IHNCFPKDVRALINQFENHNISPKLIKATDEVNDEQIKWFFDKIKNYYNNDINQKTFAVL HCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEE GLAFKPNTDDLRESRGIKLIDLLLEDGAIVKGFDYVEKARENTINKYKLDKSKAFYGYNL EEEECCCCHHHHHHCCCEEEEEECCCCCEEECHHHHHHHHHCCCHHEECCCCCEEEEEEE YVLDDLYETVKDVDAIIITTEYDFNDEDWEKINKLVKDKVVFDGRNILDMDKIKKLGFEY EEHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHEEECCCCCCCHHHHHHCCCCE YGVGRK ECCCCC >Mature Secondary Structure MKISVIGTGYVGLIQSVGLAEFGFDVVGIDIDETKVKRLNEGKCPLYEDGLEELLTNNIN CEEEEEECCHHHHHHHCCHHHCCCEEEEECCCHHHHHHCCCCCCCCHHHHHHHHHHCCCC KNLKFTTSYQEIKDSDIIFLCVGTPQDEKGNADLRFIYSATESIKKQLTKDSYKVIVLKS CCEEEEECHHHCCCCCEEEEEECCCCCCCCCCCEEEEEHHHHHHHHHHCCCCEEEEEEEE TVPIGTNRKIKESLKDYIVDVVSNPEFLREGIAVDDFFNPERIVLGFENLENKKPIEAMK CCCCCCCHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCEEEEEECCCCCCCHHHHHH KIYGEFEDKGAPIIITDWESAEMIKYASNAFLATKISFANELSKLSDEVGADIKTISEAM HHHCCCCCCCCCEEEECCCCHHHHHHHCCCEEEEHHHHHHHHHHHHHHHCCHHHHHHHHH GIDKRIGNKFLNAGIGYGGSCFHPDEILFVDFGDGLECMAFKELFDELSRDNNRSVKILS CCHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCEEEEEE INKNLKLDLANLKLITKRDYSDDLIVLKTTMGREIKITKDHPVVVLNGDKLHVKLAENIK ECCCCEEEEEEEEEEEECCCCCCEEEEEECCCCEEEEECCCCEEEEECCEEEEEEHHCCC EGDEIALPKGEFNSNSNINNIITIDILEEIKNTPLIEKTYLNNKNMVLNEFENIRAHLSN CCCCEECCCCCCCCCCCCCEEEEEEEHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHH KYIHDIKKNGTVRAKDMLPIRSILNKYNYNSNRLFTVRSKSTTIPSVIKIDGDFARLIGY HHHHHHHCCCCEEEHHCHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEECCHHHHHHHH YLAEGWISEDGKKNGAIRKRISFSFGAHEEEYINDVKNILNKLDINYIEKIRNGSHSIII HHHCCCCCCCCCCCCCHHEEEEECCCCCHHHHHHHHHHHHHHHCHHHHHHHCCCCCEEEE SSKLLAYIFEEALKCGNNCYNKQIPPQIFNSPSDIKWEFLKGILRGDGGIVKLNNNKNLN HHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCHHHHHHHHHCCCCCEEEECCCCEEE IEYGTVSKKLANSLMILLQSLGIITSLKRCYNNKSTTLTYIIRINGLNQVKKIGELFGDK EEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCHHHHHHHHHHHCCC WNNYKEIADNYERNIKPIGYKKFDNYASLKVKSVEREYYGGEVYSVETDNNLLISSYGLL CCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEHHHHHCCCEEEEEECCCCEEEEECCCH IHNCFPKDVRALINQFENHNISPKLIKATDEVNDEQIKWFFDKIKNYYNNDINQKTFAVL HCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEE GLAFKPNTDDLRESRGIKLIDLLLEDGAIVKGFDYVEKARENTINKYKLDKSKAFYGYNL EEEECCCCHHHHHHCCCEEEEEECCCCCEEECHHHHHHHHHCCCHHEECCCCCEEEEEEE YVLDDLYETVKDVDAIIITTEYDFNDEDWEKINKLVKDKVVFDGRNILDMDKIKKLGFEY EEHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHEEECCCCCCCHHHHHHCCCCE YGVGRK ECCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: 3-Acetylpyridine adenine dinucleotide; 3-Pyridinealdehyde adenine dinucleotide; Deamino adenine dinucleotide; Thionicotinamide adenine dinucleotide [C]
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): 0.05 {NAD+}} 1 {UDPglucose}} [C]
Substrates: UDP-glucose; NAD+; H2O
Specific reaction: UDP-glucose + 2 NAD+ + H2O = UDP-glucuronate + 2 NADH + 2 H+
General reaction: Redox reaction [C]
Inhibitor: NADH; UDPglucuronate; UDPxyl ose [C]
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 8688087 [H]