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The map label for this gene is rfbG [H]

Identifier: 150400819

GI number: 150400819

Start: 400056

End: 401159

Strand: Direct

Name: rfbG [H]

Synonym: Maeo_0387

Alternate gene names: 150400819

Gene position: 400056-401159 (Clockwise)

Preceding gene: 150400818

Following gene: 150400820

Centisome position: 25.49

GC content: 32.07

Gene sequence:

>1104_bases
ATGAATAATAATGCAAATGATTCTTTGTGCAAATTTTTCAAAGGAAAAAAAATTCTCATTACAGGACATACAGGGTTTAA
AGGTAGTTGGCTAACACAGGTTTTATTGAATTCTGGGGCAGATGTTATAGGGTACTCCTTGAAACCAAACACCGACCCAA
ATTTATTCAATATTTTAAATTTGGAAAAGAAAATAAAAAATTATTTTGAAGATGTTAGGGACTATAGCAAAATTAAAGAA
ATCATTGAAAAAGAAAAACCGGAAATTGTTTTTCATCTTGCTGCCCAACCATTAGTTAGAGATAGTTATGATGATCCACT
ATTTACCTATGAAACAAATGTGATTGGAACTGCAAATATCCTTCAAGCTATAAAAGAGACTAAATGTGTTAAATCAGCGG
TAATAATAACCACAGACAAAGTTTATGAAAACAAGGAATGGATTTGGGCATATAGGGAGAATGATGAACTTGGAGGGTAT
GATCCATACAGTACATCAAAGGCATGTGCTGAATTGGTGGTTAGGTCATATATAAGAGCATTTTTTAATACAAAAGATTA
TGGAGATAGACACAACACATTAATAGCATCTGTAAGGGCAGGGAATGTAATAGGGGGAGGAGATTGGTCAAAAGATAGAT
TGATTCCAGATATTATTAGAGCAATATTTGAGAAAGACGAACAAATAATCATAAGAAGTCCTGAAAGTATAAGACCTTGG
CAGCATGTGTTAGAACCTTTACTGGGTTATTTATTATTGGCACAGCATCTCTACAATGGAAAAAAAGAATTCGTCGGTGC
GTGGAATTTTGCACCAAATGAAGAAAACTTTATAAATGTTGAGAAATTGGTGAAAAAGGGAATCGAGATACTTGGAACAG
GAAAATATACTGTAAAACGGGATGATAGCAAGCATGAAATGAAAATTTTAAAGTTAGATGCCACAAAGGCTAAAACTTAT
TTAAAATGGAAACCTGTATTGAATATTGATGAAACATTGAATTGGACTTTTGAATGGTATAGGAAATATTACGATAATGA
AGACATATCATCATTTACAAATAATCAAATAAATTCGTTTTTTGATAGGTGGAAAAATGTCTGA

Upstream 100 bases:

>100_bases
CCTGAATTTTTAAGGAATTTGGGATGGTTTCCTAAGTTTTCATTGGATGAAGGTTTAAGAAAAACAATATCTTACTATCA
AAAACATCTGGTGAAGAATG

Downstream 100 bases:

>100_bases
TGAAATTAAAAATAAAATTTTAGAATTGGTAAAGGAATATTACGTTAAATCCTATGAAAAATTACCTGATAATAAAGTCC
CAGTCTCCGGGAAAGTTTAT

Product: CDP-glucose 4,6-dehydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 367; Mature: 367

Protein sequence:

>367_residues
MNNNANDSLCKFFKGKKILITGHTGFKGSWLTQVLLNSGADVIGYSLKPNTDPNLFNILNLEKKIKNYFEDVRDYSKIKE
IIEKEKPEIVFHLAAQPLVRDSYDDPLFTYETNVIGTANILQAIKETKCVKSAVIITTDKVYENKEWIWAYRENDELGGY
DPYSTSKACAELVVRSYIRAFFNTKDYGDRHNTLIASVRAGNVIGGGDWSKDRLIPDIIRAIFEKDEQIIIRSPESIRPW
QHVLEPLLGYLLLAQHLYNGKKEFVGAWNFAPNEENFINVEKLVKKGIEILGTGKYTVKRDDSKHEMKILKLDATKAKTY
LKWKPVLNIDETLNWTFEWYRKYYDNEDISSFTNNQINSFFDRWKNV

Sequences:

>Translated_367_residues
MNNNANDSLCKFFKGKKILITGHTGFKGSWLTQVLLNSGADVIGYSLKPNTDPNLFNILNLEKKIKNYFEDVRDYSKIKE
IIEKEKPEIVFHLAAQPLVRDSYDDPLFTYETNVIGTANILQAIKETKCVKSAVIITTDKVYENKEWIWAYRENDELGGY
DPYSTSKACAELVVRSYIRAFFNTKDYGDRHNTLIASVRAGNVIGGGDWSKDRLIPDIIRAIFEKDEQIIIRSPESIRPW
QHVLEPLLGYLLLAQHLYNGKKEFVGAWNFAPNEENFINVEKLVKKGIEILGTGKYTVKRDDSKHEMKILKLDATKAKTY
LKWKPVLNIDETLNWTFEWYRKYYDNEDISSFTNNQINSFFDRWKNV
>Mature_367_residues
MNNNANDSLCKFFKGKKILITGHTGFKGSWLTQVLLNSGADVIGYSLKPNTDPNLFNILNLEKKIKNYFEDVRDYSKIKE
IIEKEKPEIVFHLAAQPLVRDSYDDPLFTYETNVIGTANILQAIKETKCVKSAVIITTDKVYENKEWIWAYRENDELGGY
DPYSTSKACAELVVRSYIRAFFNTKDYGDRHNTLIASVRAGNVIGGGDWSKDRLIPDIIRAIFEKDEQIIIRSPESIRPW
QHVLEPLLGYLLLAQHLYNGKKEFVGAWNFAPNEENFINVEKLVKKGIEILGTGKYTVKRDDSKHEMKILKLDATKAKTY
LKWKPVLNIDETLNWTFEWYRKYYDNEDISSFTNNQINSFFDRWKNV

Specific function: INVOLVED IN THE SYNTHESIS OF ENTEROBACTERIAL COMMON ANTIGEN (ECA) AND REQUIRED FOR SYNTHESIS OF LIPOPOLYSACCHARIDE O-SIDE CHAINS. [C]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI7657641, Length=351, Percent_Identity=26.2108262108262, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI48994969, Length=353, Percent_Identity=25.2124645892351, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI1788353, Length=352, Percent_Identity=24.1477272727273, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1786974, Length=347, Percent_Identity=23.9193083573487, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI133901790, Length=348, Percent_Identity=24.4252873563218, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI133901788, Length=348, Percent_Identity=24.4252873563218, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI133901786, Length=348, Percent_Identity=24.4252873563218, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17539422, Length=348, Percent_Identity=24.4252873563218, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17539424, Length=348, Percent_Identity=24.4252873563218, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17507723, Length=353, Percent_Identity=24.0793201133144, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI115532424, Length=353, Percent_Identity=22.3796033994334, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013445
- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =4.2.1.45 [H]

Molecular weight: Translated: 42568; Mature: 42568

Theoretical pI: Translated: 8.36; Mature: 8.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNNANDSLCKFFKGKKILITGHTGFKGSWLTQVLLNSGADVIGYSLKPNTDPNLFNILN
CCCCCCHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHH
LEKKIKNYFEDVRDYSKIKEIIEKEKPEIVFHLAAQPLVRDSYDDPLFTYETNVIGTANI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHCCCCCCCEEEECCCCCHHHH
LQAIKETKCVKSAVIITTDKVYENKEWIWAYRENDELGGYDPYSTSKACAELVVRSYIRA
HHHHHHHHHHHHEEEEEEHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHH
FFNTKDYGDRHNTLIASVRAGNVIGGGDWSKDRLIPDIIRAIFEKDEQIIIRSPESIRPW
HHCCCCCCCCCCEEEEEEECCCEECCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCHH
QHVLEPLLGYLLLAQHLYNGKKEFVGAWNFAPNEENFINVEKLVKKGIEILGTGKYTVKR
HHHHHHHHHHHHHHHHHHCCCHHHEEECCCCCCCCCEECHHHHHHCCHHEEECCCEEEEC
DDSKHEMKILKLDATKAKTYLKWKPVLNIDETLNWTFEWYRKYYDNEDISSFTNNQINSF
CCCCCCEEEEEEECHHHHHEEEECCCCCCCHHHHHHHHHHHHHHCCCHHHHHHCHHHHHH
FDRWKNV
HHHHCCC
>Mature Secondary Structure
MNNNANDSLCKFFKGKKILITGHTGFKGSWLTQVLLNSGADVIGYSLKPNTDPNLFNILN
CCCCCCHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHH
LEKKIKNYFEDVRDYSKIKEIIEKEKPEIVFHLAAQPLVRDSYDDPLFTYETNVIGTANI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHCCCCCCCEEEECCCCCHHHH
LQAIKETKCVKSAVIITTDKVYENKEWIWAYRENDELGGYDPYSTSKACAELVVRSYIRA
HHHHHHHHHHHHEEEEEEHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHH
FFNTKDYGDRHNTLIASVRAGNVIGGGDWSKDRLIPDIIRAIFEKDEQIIIRSPESIRPW
HHCCCCCCCCCCEEEEEEECCCEECCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCHH
QHVLEPLLGYLLLAQHLYNGKKEFVGAWNFAPNEENFINVEKLVKKGIEILGTGKYTVKR
HHHHHHHHHHHHHHHHHHCCCHHHEEECCCCCCCCCEECHHHHHHCCHHEEECCCEEEEC
DDSKHEMKILKLDATKAKTYLKWKPVLNIDETLNWTFEWYRKYYDNEDISSFTNNQINSF
CCCCCCEEEEEEECHHHHHEEEECCCCCCCHHHHHHHHHHHHHHCCCHHHHHHCHHHHHH
FDRWKNV
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1710759; 11677609 [H]