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The map label for this gene is rfbF [H]

Identifier: 150400817

GI number: 150400817

Start: 398391

End: 399164

Strand: Direct

Name: rfbF [H]

Synonym: Maeo_0385

Alternate gene names: 150400817

Gene position: 398391-399164 (Clockwise)

Preceding gene: 150400816

Following gene: 150400818

Centisome position: 25.38

GC content: 33.85

Gene sequence:

>774_bases
ATGAAAGTAGTAATTTTAGCAGGAGGATTTGGAACAAGATTGTCAGAAGAAACTCACAAGATACCAAAACCAATGGTGGA
AATTGGGGGAAAACCAATTTTATGGCATATTATGAAAATATATTCTACTTATGGATATAATGACTTTGTGATATGTCTCG
GATATAAAGGATATGTAATAAAGGAATATTTTGCCAATTATTTTTTACACAACAGTGATGTAACAATAGACATTAAGAAT
AACACTATGGAAATACACAACAACTATTCTGAACCATGGAAGGTTACTCTCGTAGATACAGGACTTAATACAATGACGGG
AGGTAGAATTAAGAGAGTTGCCAAATACTTGGATGATGAAACATTCATGCTAACTTATGGTGATGGAGTGGGAAATATTA
ACATAAAAGAACTTGTTGAATTTCACAGAAACCATGGTAAATTGGCAACAGTTACTGCAACACAGCCCGAAGGAAGGTTT
GGGGCATTAAGATTAGAGGATAATAAAGTTACAAGTTTTGCTGAAAAAATGGATAATAAAGACAGCTGGATAAATGGCGG
TTTTTTTGTATTGGAACCAGAAGTAATTAACTACATAAAAGATGACACTACAATATGGGAAAGGGAACCGCTGGAAAAAT
TATCAAAAGATGGGGAGTTAATGGCGTATTTCCATAATGGTTTCTGGAAACCTATGGATAAATTAAAAGATAAGATGGAA
TTGGAAGAAATGTGGAATTCAGGTAATGCACCATGGAAAATATGGGGTGAGTAA

Upstream 100 bases:

>100_bases
ACTGTCGTATATACATAATTAGATATAATACTCCGTATGATTAACAATATGATGGAATTTTTTATAACATTTACTTTAAA
TTAGGCGTAATGGTGAAATC

Downstream 100 bases:

>100_bases
TATTGTCTAAAACAATATTATTAACAGGGGCCACTGGGTTCTTGGGAAGTCATTTATTGGAAATGTTGGTAAAAGAAGGG
AATAATGTTATCATTTTAAA

Product: glucose-1-phosphate cytidylyltransferase

Products: NA

Alternate protein names: CDP-glucose pyrophosphorylase [H]

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MKVVILAGGFGTRLSEETHKIPKPMVEIGGKPILWHIMKIYSTYGYNDFVICLGYKGYVIKEYFANYFLHNSDVTIDIKN
NTMEIHNNYSEPWKVTLVDTGLNTMTGGRIKRVAKYLDDETFMLTYGDGVGNINIKELVEFHRNHGKLATVTATQPEGRF
GALRLEDNKVTSFAEKMDNKDSWINGGFFVLEPEVINYIKDDTTIWEREPLEKLSKDGELMAYFHNGFWKPMDKLKDKME
LEEMWNSGNAPWKIWGE

Sequences:

>Translated_257_residues
MKVVILAGGFGTRLSEETHKIPKPMVEIGGKPILWHIMKIYSTYGYNDFVICLGYKGYVIKEYFANYFLHNSDVTIDIKN
NTMEIHNNYSEPWKVTLVDTGLNTMTGGRIKRVAKYLDDETFMLTYGDGVGNINIKELVEFHRNHGKLATVTATQPEGRF
GALRLEDNKVTSFAEKMDNKDSWINGGFFVLEPEVINYIKDDTTIWEREPLEKLSKDGELMAYFHNGFWKPMDKLKDKME
LEEMWNSGNAPWKIWGE
>Mature_257_residues
MKVVILAGGFGTRLSEETHKIPKPMVEIGGKPILWHIMKIYSTYGYNDFVICLGYKGYVIKEYFANYFLHNSDVTIDIKN
NTMEIHNNYSEPWKVTLVDTGLNTMTGGRIKRVAKYLDDETFMLTYGDGVGNINIKELVEFHRNHGKLATVTATQPEGRF
GALRLEDNKVTSFAEKMDNKDSWINGGFFVLEPEVINYIKDDTTIWEREPLEKLSKDGELMAYFHNGFWKPMDKLKDKME
LEEMWNSGNAPWKIWGE

Specific function: Involved in the biosynthesis of the tyvelose, a 3,6- dideoxyhexose found in the O-antigen of the surface lipopolysaccharides. It catalyzes the transfer of a CMP moiety from CTP to glucose 1-phosphate. This enzyme can utilize either CTP or UTP as the nucle

COG id: COG1208

COG function: function code MJ; Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucose-1-phosphate cytidylyltransferase family [H]

Homologues:

Organism=Caenorhabditis elegans, GI133931050, Length=243, Percent_Identity=27.1604938271605, Blast_Score=96, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6320148, Length=246, Percent_Identity=28.4552845528455, Blast_Score=96, Evalue=5e-21,
Organism=Drosophila melanogaster, GI21355443, Length=244, Percent_Identity=27.4590163934426, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24644084, Length=244, Percent_Identity=27.4590163934426, Blast_Score=94, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013446
- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.33 [H]

Molecular weight: Translated: 29685; Mature: 29685

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVVILAGGFGTRLSEETHKIPKPMVEIGGKPILWHIMKIYSTYGYNDFVICLGYKGYVI
CEEEEEECCCCCCCCHHHHHCCCHHHHHCCCHHHHHHHHHHHHCCCCCEEEEECCCCCHH
KEYFANYFLHNSDVTIDIKNNTMEIHNNYSEPWKVTLVDTGLNTMTGGRIKRVAKYLDDE
HHHHHHHEEECCCEEEEEECCEEEEECCCCCCEEEEEEECCCCCCCCHHHHHHHHHCCCC
TFMLTYGDGVGNINIKELVEFHRNHGKLATVTATQPEGRFGALRLEDNKVTSFAEKMDNK
EEEEEECCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCEEEEEEECCHHHHHHHHCCCC
DSWINGGFFVLEPEVINYIKDDTTIWEREPLEKLSKDGELMAYFHNGFWKPMDKLKDKME
CCEECCCEEEECHHHHHHHCCCCCCCCCCHHHHHCCCCCEEEEEECCCCCHHHHHHHHHH
LEEMWNSGNAPWKIWGE
HHHHHCCCCCCEEECCC
>Mature Secondary Structure
MKVVILAGGFGTRLSEETHKIPKPMVEIGGKPILWHIMKIYSTYGYNDFVICLGYKGYVI
CEEEEEECCCCCCCCHHHHHCCCHHHHHCCCHHHHHHHHHHHHCCCCCEEEEECCCCCHH
KEYFANYFLHNSDVTIDIKNNTMEIHNNYSEPWKVTLVDTGLNTMTGGRIKRVAKYLDDE
HHHHHHHEEECCCEEEEEECCEEEEECCCCCCEEEEEEECCCCCCCCHHHHHHHHHCCCC
TFMLTYGDGVGNINIKELVEFHRNHGKLATVTATQPEGRFGALRLEDNKVTSFAEKMDNK
EEEEEECCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCEEEEEEECCHHHHHHHHCCCC
DSWINGGFFVLEPEVINYIKDDTTIWEREPLEKLSKDGELMAYFHNGFWKPMDKLKDKME
CCEECCCEEEECHHHHHHHCCCCCCCCCCHHHHHCCCCCEEEEEECCCCCHHHHHHHHHH
LEEMWNSGNAPWKIWGE
HHHHHCCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]