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The map label for this gene is rfbC [H]

Identifier: 150400816

GI number: 150400816

Start: 396406

End: 396963

Strand: Direct

Name: rfbC [H]

Synonym: Maeo_0383

Alternate gene names: 150400816

Gene position: 396406-396963 (Clockwise)

Preceding gene: 150400815

Following gene: 150400817

Centisome position: 25.26

GC content: 34.41

Gene sequence:

>558_bases
ATGCCATTTGAATTTATGAAAACCAAAATTTCAGAAGTGATATTAATAAAACCAAAAATTTTTGGAGACGAAAGAGGATT
TTTTTTAGAAACATATGAAAAAGAAGATTTTGAAAATGCAGGCATTAAAGGAGAATTTGTTCAGGACAATCATTCTAAAT
CTTGTCATGGTGTGTTAAGAGGATTACATTTTCAAAAAGAACCTTATGCACAAGCTAAAATAGTTAGGTGTATTAAAGGA
GTTATTTTTGATGTTGCTGTGGATTTAAGGGGGAGCTCTCCAACATTTGGGCAGTGGGTAGGGGTTGTGCTGTCAGAGTA
TAATAAACATCAATTGTATATTCCAAGGGGATTTGCCCATGGTTTTTGCGTTTTAAGTGATGAGGCAGAGGTAGTATATA
AGGTGGATAATAAATATGCTCCTGAATGTGAATGCGGAGTAATTTGGAATGATGAAGATATTGGTATTGACTGGCTTATT
GATGAACCAATACTGTCCGATAAGGATAAACAATGGCATACTTTAAAGGAGTTGGATGAGAAGGGTGAGCTCTTTTAA

Upstream 100 bases:

>100_bases
TTCTTCGTTTTTTAGTACTGGATAAATATTTACATATAATAGGCGATTTAGGGAAATATTTCGAAGATTTACTATAAATA
AAAGAAAGGTGTGTGATACT

Downstream 100 bases:

>100_bases
TTAGAGAAAGTGAAATTAAAGAAATACTATCAATTTTAGAGGGAGAACCTAACTTAATATATTTCATCTACGGTTCTATA
AATAGTGGAAAATCTACTTT

Product: dTDP-4-dehydrorhamnose 3,5-epimerase

Products: NA

Alternate protein names: Thymidine diphospho-4-keto-rhamnose 3,5-epimerase; dTDP-4-keto-6-deoxyglucose 3,5-epimerase; dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase; dTDP-L-rhamnose synthase [H]

Number of amino acids: Translated: 185; Mature: 184

Protein sequence:

>185_residues
MPFEFMKTKISEVILIKPKIFGDERGFFLETYEKEDFENAGIKGEFVQDNHSKSCHGVLRGLHFQKEPYAQAKIVRCIKG
VIFDVAVDLRGSSPTFGQWVGVVLSEYNKHQLYIPRGFAHGFCVLSDEAEVVYKVDNKYAPECECGVIWNDEDIGIDWLI
DEPILSDKDKQWHTLKELDEKGELF

Sequences:

>Translated_185_residues
MPFEFMKTKISEVILIKPKIFGDERGFFLETYEKEDFENAGIKGEFVQDNHSKSCHGVLRGLHFQKEPYAQAKIVRCIKG
VIFDVAVDLRGSSPTFGQWVGVVLSEYNKHQLYIPRGFAHGFCVLSDEAEVVYKVDNKYAPECECGVIWNDEDIGIDWLI
DEPILSDKDKQWHTLKELDEKGELF
>Mature_184_residues
PFEFMKTKISEVILIKPKIFGDERGFFLETYEKEDFENAGIKGEFVQDNHSKSCHGVLRGLHFQKEPYAQAKIVRCIKGV
IFDVAVDLRGSSPTFGQWVGVVLSEYNKHQLYIPRGFAHGFCVLSDEAEVVYKVDNKYAPECECGVIWNDEDIGIDWLID
EPILSDKDKQWHTLKELDEKGELF

Specific function: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose [H]

COG id: COG1898

COG function: function code M; dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI1788350, Length=175, Percent_Identity=56, Blast_Score=201, Evalue=3e-53,
Organism=Caenorhabditis elegans, GI17550412, Length=174, Percent_Identity=49.4252873563218, Blast_Score=152, Evalue=9e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR000888
- InterPro:   IPR014710
- ProDom:   PD001462 [H]

Pfam domain/function: PF00908 dTDP_sugar_isom [H]

EC number: =5.1.3.13 [H]

Molecular weight: Translated: 21296; Mature: 21165

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFEFMKTKISEVILIKPKIFGDERGFFLETYEKEDFENAGIKGEFVQDNHSKSCHGVLR
CCHHHHHHHHCEEEEECCEEECCCCCCEEEECCCCCCCCCCCCCEEECCCCCCHHHHHHH
GLHFQKEPYAQAKIVRCIKGVIFDVAVDLRGSSPTFGQWVGVVLSEYNKHQLYIPRGFAH
HCCCCCCCHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHCCCCCEEEEECCCCC
GFCVLSDEAEVVYKVDNKYAPECECGVIWNDEDIGIDWLIDEPILSDKDKQWHTLKELDE
CEEEEECCCEEEEEECCCCCCCCCEEEEECCCCCCEEEEECCCCCCCCCCCHHHHHHHHH
KGELF
CCCCC
>Mature Secondary Structure 
PFEFMKTKISEVILIKPKIFGDERGFFLETYEKEDFENAGIKGEFVQDNHSKSCHGVLR
CHHHHHHHHCEEEEECCEEECCCCCCEEEECCCCCCCCCCCCCEEECCCCCCHHHHHHH
GLHFQKEPYAQAKIVRCIKGVIFDVAVDLRGSSPTFGQWVGVVLSEYNKHQLYIPRGFAH
HCCCCCCCHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHCCCCCEEEEECCCCC
GFCVLSDEAEVVYKVDNKYAPECECGVIWNDEDIGIDWLIDEPILSDKDKQWHTLKELDE
CEEEEECCCEEEEEECCCCCCCCCEEEEECCCCCCEEEEECCCCCCCCCCCHHHHHHHHH
KGELF
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8170390; 8157605; 12384590; 12704152 [H]