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The map label for this gene is aroA

Identifier: 150400587

GI number: 150400587

Start: 167239

End: 168540

Strand: Reverse

Name: aroA

Synonym: Maeo_0149

Alternate gene names: 150400587

Gene position: 168540-167239 (Counterclockwise)

Preceding gene: 150400589

Following gene: 150400586

Centisome position: 10.74

GC content: 33.95

Gene sequence:

>1302_bases
GTGATAATAATAGAAAAAACAGAACAAATAAAGGGAACTATAAATGCCCCTCCTTCAAAATCTTACACCCACAGGGCAGT
AATTTGTGCCTCACTGGCAGACGGAACCTCTGAAATAATTAGTCCTTTAAATAGTGCTGACTGTCTTTCGTCTGTTCATG
GTGCTATGATGCTTGGGGCCGAAATTGATGCAACGGATAAAAATAAATGGGTTGTGGTGGGAAATAATAACAGCCCTAAA
ACTCCAAATAATGTTGTAGATATTGGAAACAGCGGAACAACTCTAAGGATTTTAACAGGAATAGCCTCCCAAATACCAGA
AGGATATGCCATATTAACAGGAGATAGCTCTATTATAACCAGACCAATGCAACCGCTACTTGATGCTTTAAATCAATTAG
GTATTAGAGCTTTTTCATCTAAAACAGACGGAACCGCCCCGATTATTGTAGAACATGGCGAAATAAAAAATAATGTTGTA
AAAATAAGAGGGGATATGAGCTCCCAATTTATTACCTCATTAATGATGACGATGCCATTTTCAAAAATGGATTCTACCAT
TGAATTAACTACTCCTTTAAAATCAGCACCTTATTTAGATATTACAATTGATGTATTGGATAAATTTGGAGTAAAAATAG
AAAAAGTGAAAAATAAAAATAAATTAACCAAATTTATCATTAAAGGAAATCAAAAATATAAACCATACTCCTATACTGTG
GAGGGCGATTGTTCTTCGGCATCATACTTTATAGCAGCAGGAGTGCTTATGAATTCCGATATTACAATAAATAATATATT
CAAAAACTCAAAACAGGGTGATAGAGAAATAGTAAATATTGTTAAAAAAATGGGAGCTCCCATAATAGAGGAAGAGGATA
AAATAATAATTAAAGGACCATATAAATTAAAAGGTATAGATATAGATGTAAAGGATACTCCTGATCTAGTGCCTACAATT
GCTATATTGGGCTGTTTTGCGGAAGGAACAACAACAATATATAACGGCGAACATGTTAGATTAAAAGAATGCGATAGATT
AATGGCTTGTGCAAAGGAATTAACTAAAATGGGAGCAAAAATAACAGAAAAACCAGACGGTTTAATTATTGAAGGAGTTG
GAAAATTAAATGGGGCAGAAATGGAGACATACCACGACCATAGGCTTGTTATGGCTTTCACGGTGGCTGGAATGATGGCA
GAGGGAAAAACAATAATTAAAGGAGAGGATGCTGTTAAAATATCATTCCCTAATTTTGTGGAAGCAATTAAATCAATTGG
GGCAAATATTACTATTAAATAA

Upstream 100 bases:

>100_bases
GTACGATATTATGTGATAAATACCCAAAGATATTATAATATTTATGATATTAATATTTATAATTTATAATCAACAATAAA
ATAAAAAAGCGGTGGTATAT

Downstream 100 bases:

>100_bases
TATAAATTTTTATAATTCTATAAAATTATAATTAAAATATAAAACCGCGAGAAATAAAAGATGATATAATATGGCAATAC
ACAAAATAAAAGAATTTATG

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MIIIEKTEQIKGTINAPPSKSYTHRAVICASLADGTSEIISPLNSADCLSSVHGAMMLGAEIDATDKNKWVVVGNNNSPK
TPNNVVDIGNSGTTLRILTGIASQIPEGYAILTGDSSIITRPMQPLLDALNQLGIRAFSSKTDGTAPIIVEHGEIKNNVV
KIRGDMSSQFITSLMMTMPFSKMDSTIELTTPLKSAPYLDITIDVLDKFGVKIEKVKNKNKLTKFIIKGNQKYKPYSYTV
EGDCSSASYFIAAGVLMNSDITINNIFKNSKQGDREIVNIVKKMGAPIIEEEDKIIIKGPYKLKGIDIDVKDTPDLVPTI
AILGCFAEGTTTIYNGEHVRLKECDRLMACAKELTKMGAKITEKPDGLIIEGVGKLNGAEMETYHDHRLVMAFTVAGMMA
EGKTIIKGEDAVKISFPNFVEAIKSIGANITIK

Sequences:

>Translated_433_residues
MIIIEKTEQIKGTINAPPSKSYTHRAVICASLADGTSEIISPLNSADCLSSVHGAMMLGAEIDATDKNKWVVVGNNNSPK
TPNNVVDIGNSGTTLRILTGIASQIPEGYAILTGDSSIITRPMQPLLDALNQLGIRAFSSKTDGTAPIIVEHGEIKNNVV
KIRGDMSSQFITSLMMTMPFSKMDSTIELTTPLKSAPYLDITIDVLDKFGVKIEKVKNKNKLTKFIIKGNQKYKPYSYTV
EGDCSSASYFIAAGVLMNSDITINNIFKNSKQGDREIVNIVKKMGAPIIEEEDKIIIKGPYKLKGIDIDVKDTPDLVPTI
AILGCFAEGTTTIYNGEHVRLKECDRLMACAKELTKMGAKITEKPDGLIIEGVGKLNGAEMETYHDHRLVMAFTVAGMMA
EGKTIIKGEDAVKISFPNFVEAIKSIGANITIK
>Mature_433_residues
MIIIEKTEQIKGTINAPPSKSYTHRAVICASLADGTSEIISPLNSADCLSSVHGAMMLGAEIDATDKNKWVVVGNNNSPK
TPNNVVDIGNSGTTLRILTGIASQIPEGYAILTGDSSIITRPMQPLLDALNQLGIRAFSSKTDGTAPIIVEHGEIKNNVV
KIRGDMSSQFITSLMMTMPFSKMDSTIELTTPLKSAPYLDITIDVLDKFGVKIEKVKNKNKLTKFIIKGNQKYKPYSYTV
EGDCSSASYFIAAGVLMNSDITINNIFKNSKQGDREIVNIVKKMGAPIIEEEDKIIIKGPYKLKGIDIDVKDTPDLVPTI
AILGCFAEGTTTIYNGEHVRLKECDRLMACAKELTKMGAKITEKPDGLIIEGVGKLNGAEMETYHDHRLVMAFTVAGMMA
EGKTIIKGEDAVKISFPNFVEAIKSIGANITIK

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family

Homologues:

Organism=Escherichia coli, GI1787137, Length=430, Percent_Identity=35.3488372093023, Blast_Score=232, Evalue=4e-62,
Organism=Saccharomyces cerevisiae, GI6320332, Length=417, Percent_Identity=31.6546762589928, Blast_Score=172, Evalue=9e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROA_META3 (A6UTB9)

Other databases:

- EMBL:   CP000743
- RefSeq:   YP_001324353.1
- STRING:   A6UTB9
- GeneID:   5327505
- GenomeReviews:   CP000743_GR
- KEGG:   mae:Maeo_0149
- eggNOG:   arNOG05032
- HOGENOM:   HBG646626
- OMA:   SSQFITS
- ProtClustDB:   PRK02427
- BioCyc:   MAEO419665:MAEO_0149-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00210
- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792
- Gene3D:   G3DSA:3.65.10.10
- PIRSF:   PIRSF000505
- TIGRFAMs:   TIGR01356

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.19

Molecular weight: Translated: 46952; Mature: 46952

Theoretical pI: Translated: 7.46; Mature: 7.46

Prosite motif: PS00104 EPSP_SYNTHASE_1; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIIEKTEQIKGTINAPPSKSYTHRAVICASLADGTSEIISPLNSADCLSSVHGAMMLGA
CEEEECCHHCCEEECCCCCCCCCCEEEEEEECCCCHHHHHCCCCHHHHHHHHHHHEEECC
EIDATDKNKWVVVGNNNSPKTPNNVVDIGNSGTTLRILTGIASQIPEGYAILTGDSSIIT
EECCCCCCCEEEEECCCCCCCCCCEEEECCCCCEEEEEHHHHHHCCCCEEEEECCCHHHH
RPMQPLLDALNQLGIRAFSSKTDGTAPIIVEHGEIKNNVVKIRGDMSSQFITSLMMTMPF
CCHHHHHHHHHHHCCEEECCCCCCCCCEEEECCCCCCCEEEEECCCHHHHHHHHHHHCCH
SKMDSTIELTTPLKSAPYLDITIDVLDKFGVKIEKVKNKNKLTKFIIKGNQKYKPYSYTV
HHCCCEEEEECCCCCCCEEEEEHEEHHHHCCEEEECCCCCCEEEEEEECCCCCCCEEEEE
EGDCSSASYFIAAGVLMNSDITINNIFKNSKQGDREIVNIVKKMGAPIIEEEDKIIIKGP
CCCCCCCCEEEEEEEEECCCEEEEHHHCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEECC
YKLKGIDIDVKDTPDLVPTIAILGCFAEGTTTIYNGEHVRLKECDRLMACAKELTKMGAK
EEEEEEEEECCCCCCHHHHHHHHHHHCCCCEEEECCCEEEHHHHHHHHHHHHHHHHCCCE
ITEKPDGLIIEGVGKLNGAEMETYHDHRLVMAFTVAGMMAEGKTIIKGEDAVKISFPNFV
ECCCCCCEEEEECCCCCCCEEEEECCCEEEEEHHHHHHHHCCCEEEECCCEEEEECHHHH
EAIKSIGANITIK
HHHHHCCCCEEEC
>Mature Secondary Structure
MIIIEKTEQIKGTINAPPSKSYTHRAVICASLADGTSEIISPLNSADCLSSVHGAMMLGA
CEEEECCHHCCEEECCCCCCCCCCEEEEEEECCCCHHHHHCCCCHHHHHHHHHHHEEECC
EIDATDKNKWVVVGNNNSPKTPNNVVDIGNSGTTLRILTGIASQIPEGYAILTGDSSIIT
EECCCCCCCEEEEECCCCCCCCCCEEEECCCCCEEEEEHHHHHHCCCCEEEEECCCHHHH
RPMQPLLDALNQLGIRAFSSKTDGTAPIIVEHGEIKNNVVKIRGDMSSQFITSLMMTMPF
CCHHHHHHHHHHHCCEEECCCCCCCCCEEEECCCCCCCEEEEECCCHHHHHHHHHHHCCH
SKMDSTIELTTPLKSAPYLDITIDVLDKFGVKIEKVKNKNKLTKFIIKGNQKYKPYSYTV
HHCCCEEEEECCCCCCCEEEEEHEEHHHHCCEEEECCCCCCEEEEEEECCCCCCCEEEEE
EGDCSSASYFIAAGVLMNSDITINNIFKNSKQGDREIVNIVKKMGAPIIEEEDKIIIKGP
CCCCCCCCEEEEEEEEECCCEEEEHHHCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEECC
YKLKGIDIDVKDTPDLVPTIAILGCFAEGTTTIYNGEHVRLKECDRLMACAKELTKMGAK
EEEEEEEEECCCCCCHHHHHHHHHHHCCCCEEEECCCEEEHHHHHHHHHHHHHHHHCCCE
ITEKPDGLIIEGVGKLNGAEMETYHDHRLVMAFTVAGMMAEGKTIIKGEDAVKISFPNFV
ECCCCCCEEEEECCCCCCCEEEEECCCEEEEEHHHHHHHHCCCEEEECCCEEEEECHHHH
EAIKSIGANITIK
HHHHHCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA