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The map label for this gene is aroD

Identifier: 150400570

GI number: 150400570

Start: 148548

End: 149204

Strand: Direct

Name: aroD

Synonym: Maeo_0132

Alternate gene names: 150400570

Gene position: 148548-149204 (Clockwise)

Preceding gene: 150400569

Following gene: 150400572

Centisome position: 9.46

GC content: 29.98

Gene sequence:

>657_bases
ATGATTTGTATTCCAGTAATTGATAAAAATATAAATGATGCTTTAAAAAGTGCAGAAGAGGCTTTAAAAGTAGCCGATAT
AGTGGAATTTAGGGCAGACCTACTTGAAAGCGTAGATAAACAAGATATAGAAAAAATGGCAAAATATCCTTCAATAATTA
CAATTAGGGCAGATTGGGAAGGTGGAGAATATACTGGAGATAATAATAAAAGAATAGAGTTATATAAAACAGCAATTGAA
AATAATGTAAAATTCATAGATATTGAATTAAAGGAAGAAAAAAATAAAGAACTTGTTGAATTTAGAAATAAAATAGGCTC
AAAAACTAAAATTATTGTATCATATCATGATTTTGAAAAAACTCCATCTAAACAGGATTTAATGGAAATTGTGGAGAAAG
AGTTAAAAATTGGAGATATTGCTAAATTTGCCACAATGGCACAAAATAAAAATGATTTATTAAAGATTTTTGCAGTAATT
AGTATTTATGAAGGCAAAATAATTGGTATAGGAATGGGAGAAGTTGGTAAATTAACGAGAATAATCGGGGTCGAATTAGG
TTCAATTTTAACCTTTGCATCTATGGAGGGCAGGAGCTCCGCACCCGGTCAGGTTGATGTTGTTAAGTTGAAGAAAATAT
GGGAGCTCCTGAAATAA

Upstream 100 bases:

>100_bases
GAGAGGTTGAAGGCATAGGGGAGATAACAGCTAAAAAAATAAAATCAGTTCTTACAGAAAAATATGAGAAATAAATAACA
AAAGGTGTGTGTGATACTAT

Downstream 100 bases:

>100_bases
TTATAATATAATTATCTTAAAAATTAAATTTTCTCCTTTTTTTAATCTTTCCACAATTTCACGATTTAAATCATTTGCAC
TTTTATCCGCATTTATAATC

Product: 3-dehydroquinate dehydratase, type I

Products: NA

Alternate protein names: 3-dehydroquinase; Type I DHQase

Number of amino acids: Translated: 218; Mature: 218

Protein sequence:

>218_residues
MICIPVIDKNINDALKSAEEALKVADIVEFRADLLESVDKQDIEKMAKYPSIITIRADWEGGEYTGDNNKRIELYKTAIE
NNVKFIDIELKEEKNKELVEFRNKIGSKTKIIVSYHDFEKTPSKQDLMEIVEKELKIGDIAKFATMAQNKNDLLKIFAVI
SIYEGKIIGIGMGEVGKLTRIIGVELGSILTFASMEGRSSAPGQVDVVKLKKIWELLK

Sequences:

>Translated_218_residues
MICIPVIDKNINDALKSAEEALKVADIVEFRADLLESVDKQDIEKMAKYPSIITIRADWEGGEYTGDNNKRIELYKTAIE
NNVKFIDIELKEEKNKELVEFRNKIGSKTKIIVSYHDFEKTPSKQDLMEIVEKELKIGDIAKFATMAQNKNDLLKIFAVI
SIYEGKIIGIGMGEVGKLTRIIGVELGSILTFASMEGRSSAPGQVDVVKLKKIWELLK
>Mature_218_residues
MICIPVIDKNINDALKSAEEALKVADIVEFRADLLESVDKQDIEKMAKYPSIITIRADWEGGEYTGDNNKRIELYKTAIE
NNVKFIDIELKEEKNKELVEFRNKIGSKTKIIVSYHDFEKTPSKQDLMEIVEKELKIGDIAKFATMAQNKNDLLKIFAVI
SIYEGKIIGIGMGEVGKLTRIIGVELGSILTFASMEGRSSAPGQVDVVKLKKIWELLK

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; third step. [C]

COG id: COG0710

COG function: function code E; 3-dehydroquinate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-I 3-dehydroquinase family

Homologues:

Organism=Escherichia coli, GI1787984, Length=211, Percent_Identity=32.2274881516588, Blast_Score=85, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6320332, Length=209, Percent_Identity=29.1866028708134, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROD_META3 (A6UTA2)

Other databases:

- EMBL:   CP000743
- RefSeq:   YP_001324336.1
- ProteinModelPortal:   A6UTA2
- SMR:   A6UTA2
- STRING:   A6UTA2
- GeneID:   5327108
- GenomeReviews:   CP000743_GR
- KEGG:   mae:Maeo_0132
- eggNOG:   arNOG12575
- HOGENOM:   HBG732926
- OMA:   NHDFDKT
- ProtClustDB:   CLSK876583
- BioCyc:   MAEO419665:MAEO_0132-MONOMER
- HAMAP:   MF_00214
- InterPro:   IPR018508
- InterPro:   IPR013785
- InterPro:   IPR001381
- Gene3D:   G3DSA:3.20.20.70
- TIGRFAMs:   TIGR01093

Pfam domain/function: PF01487 DHquinase_I

EC number: =4.2.1.10

Molecular weight: Translated: 24567; Mature: 24567

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: PS01028 DEHYDROQUINASE_I

Important sites: ACT_SITE 116-116 ACT_SITE 142-142

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MICIPVIDKNINDALKSAEEALKVADIVEFRADLLESVDKQDIEKMAKYPSIITIRADWE
CEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCEEEEEECCC
GGEYTGDNNKRIELYKTAIENNVKFIDIELKEEKNKELVEFRNKIGSKTKIIVSYHDFEK
CCCEECCCCCEEEEEEEHHHCCCEEEEEEECCCCCHHHHHHHHHCCCCEEEEEEEECCCC
TPSKQDLMEIVEKELKIGDIAKFATMAQNKNDLLKIFAVISIYEGKIIGIGMGEVGKLTR
CCCHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCEEEEECCCCHHHHHH
IIGVELGSILTFASMEGRSSAPGQVDVVKLKKIWELLK
HHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHC
>Mature Secondary Structure
MICIPVIDKNINDALKSAEEALKVADIVEFRADLLESVDKQDIEKMAKYPSIITIRADWE
CEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCEEEEEECCC
GGEYTGDNNKRIELYKTAIENNVKFIDIELKEEKNKELVEFRNKIGSKTKIIVSYHDFEK
CCCEECCCCCEEEEEEEHHHCCCEEEEEEECCCCCHHHHHHHHHCCCCEEEEEEEECCCC
TPSKQDLMEIVEKELKIGDIAKFATMAQNKNDLLKIFAVISIYEGKIIGIGMGEVGKLTR
CCCHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCEEEEECCCCHHHHHH
IIGVELGSILTFASMEGRSSAPGQVDVVKLKKIWELLK
HHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA