| Definition | Methanococcus aeolicus Nankai-3, complete genome. |
|---|---|
| Accession | NC_009635 |
| Length | 1,569,500 |
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The map label for this gene is srmB [C]
Identifier: 150400569
GI number: 150400569
Start: 146095
End: 148521
Strand: Direct
Name: srmB [C]
Synonym: Maeo_0131
Alternate gene names: 150400569
Gene position: 146095-148521 (Clockwise)
Preceding gene: 150400568
Following gene: 150400570
Centisome position: 9.31
GC content: 31.11
Gene sequence:
>2427_bases ATGAATATAACTCACCCACTTATAAAACCAAATACGATGGAAGCACGAATATATCAGCAAACTATGGTGGCAAATGCCCT TAGAAAAAATACGCTATGCGTATTGGGGACAGGATTGGGAAAAACTGCCATAGCAACTCTTACAATTGCGGGAATATTGT CAAAAAACAATAATAAAAATATAAATAAAAAAGTCCTAATTATAGCTCCGTCTCGTCCATTGGTAGAACAACATTACAAT AGTTTAAAAACTTTTTTAAATATTCCGGAGGATAAGATAGTTGTTTTAACTGGAAAAATAGCTCCTGCAAAGAGGCAAAA GATATGGGAAGAAGGGAAAATATTTATTGCAACCCCTCAAATTGTGGAAAATGATATTGTGGCAAATAGGGTAAATACTG ATGACTTTGCCCTATTAATCGCCGATGAGGCACACCACACCACAGGAAATCATTCTTATTCTTTTGTAGCTTCGGTATTT AGGAATAAGTCCCATATATTGGGATTAACAGCTTCCCCGGGCTCAAATATTGAGAAAATATTGGAAGTATGTAAAAATTT AGGTATTGAGCATGTGGAAATAAGAACAATAGATGATATTGATGTTAAAGAGTATGTTCAAACAGTGAAATTACGACCTA TTAAAGTGGAGCTCCCAAAAGAATTTGCTGAATGTATAAATTTATTAAAACAGGCCCAAATGGAACGACTGAAAATATTA AGAGACCATAAAATAATTTATTCCACCAATGTAAATAAAACAGAATTATTACAGCTTCAAAAAAGAATTATGGTAATTGA AGATAATTCTAAATATGAACTAATAAAAATAGCCTCCGAAGCAATAAAATTAGATTATGCCATTGAAACCCTTGAATGCC AGGGAAAAGAGGCATTTTTAAATTATTATGAACGGTTAAGTAGTCAGGACACAAAATCGGCAAAAGCCATAATTAAAGAT TCAAAAGTTTTAAAGGTGGCATATTCATTAAGAACTACTGAATTAGAGCACCCAAAAACTGAAAAACTTTTGGAAGTTGT AAATGATGTATTGAATAAAGAAGAAGGAAAAAAAGAAAAAAAGAACACTAAAAAAAAGAACACTAATAATACCAACAATA TTGATAATAATAATAAAACAATAATATTTGCCCAATATCGGGACACAGTAGAAAAGATAGTAAATTTATTAAATTCAAAC GGAATACAGGCAATACCTTTTGTAGGGCAATCTAATAAAGACGGAAAAGGAATGTCTCAGAAAAAACAAATTGAGGCAGT TGAAAAATTTAAAAATGACCCCGCCGTAAATGTTTTGGTCTCTACCAGCGTATCTGAGGAGGGTATAGATATAATGAGTG TAAATTTCGTTATATTTTATGAGCCGGTGCCTTCTGAAATAAGATTTATACAACGGCGAGGTAGGGCATCTCGTGGGGAA GGGGGGGAGTGTATTGTATTAATTACAAAAGATAGCCGTGATGAGGGATATTACTGGTCAGCCCTAAATAAAGAGCGGAA AATGAAAAGAATTTTAAAAGATATGCAAAAAATATTAAATGAGAAATTAAACGAGGAAAATGCACATAAATATATAATTG AGGATAAAAATACGATAGATTATCATATAAATAAAGAAAATAATAAGATGGCAGAAAAAGAAAATAACAAAATAGGCGAT ACAAATGGTAAAATATCTATTGAAGAAGATTGTAAAAATAATGTTAAAAAGGAAATTAAAGAAAATATTAACGAGATAAT AGAAAATAAAAATAATATCGTACTGTCGAATAAATGTTCCACAAAACCAGTTAAAATAATAGTGGATAGCAGGGAAAAAA TAATAAGTAGATATATTTATGATAAAGCAGATTTGGAGTTTAAAGCCCTTGATAATGGGGATTTTATATTAAGTGATAGA GTAATAGTGGAGCGAAAAACAGCCGAAGATTTAGAGGGCTCCATAATTGATAAAAGATTATTCAAACAATTGAAAGATTT AAAAAAATATGAAAGACCGATTTTAATTGTGGAGGGCAATGATTATTTTAGATTGTCCGAAAAAATAATAAATGGAACTA TGGTTTCTATAATGTTGGATTTTAACATACCTGTAATTTTTACGAAAGATATGGAAGAGACGGCGAATATATTAATAAAA ATGGCAGAACGGGAGCAGTTGCGGGATAAAAGAACAATATCCATAAGGACAGGAAAAAAACCAATGTCTTTAAAAGAAAG ACAAAGATTTATAGTTGAAAGTTTTCCAGATATTGGAGCTCTCATGGCCGAAAATTTACTTATAAAATTTGGCACAATTG AAAATATTGTTAAGGCATCTGTGGAGGAGCTCCGAGAGGTTGAAGGCATAGGGGAGATAACAGCTAAAAAAATAAAATCA GTTCTTACAGAAAAATATGAGAAATAA
Upstream 100 bases:
>100_bases AGAAATAGAGAATAAAATAAATATATAAAATCCTAAAAGGAGTTTATTCAAAAGCAGAGCTTTTGTATAAAAAATAAATT AAAAAATACGGGTATAAAAT
Downstream 100 bases:
>100_bases ATAACAAAAGGTGTGTGTGATACTATATGATTTGTATTCCAGTAATTGATAAAAATATAAATGATGCTTTAAAAAGTGCA GAAGAGGCTTTAAAAGTAGC
Product: Hef nuclease
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 808; Mature: 808
Protein sequence:
>808_residues MNITHPLIKPNTMEARIYQQTMVANALRKNTLCVLGTGLGKTAIATLTIAGILSKNNNKNINKKVLIIAPSRPLVEQHYN SLKTFLNIPEDKIVVLTGKIAPAKRQKIWEEGKIFIATPQIVENDIVANRVNTDDFALLIADEAHHTTGNHSYSFVASVF RNKSHILGLTASPGSNIEKILEVCKNLGIEHVEIRTIDDIDVKEYVQTVKLRPIKVELPKEFAECINLLKQAQMERLKIL RDHKIIYSTNVNKTELLQLQKRIMVIEDNSKYELIKIASEAIKLDYAIETLECQGKEAFLNYYERLSSQDTKSAKAIIKD SKVLKVAYSLRTTELEHPKTEKLLEVVNDVLNKEEGKKEKKNTKKKNTNNTNNIDNNNKTIIFAQYRDTVEKIVNLLNSN GIQAIPFVGQSNKDGKGMSQKKQIEAVEKFKNDPAVNVLVSTSVSEEGIDIMSVNFVIFYEPVPSEIRFIQRRGRASRGE GGECIVLITKDSRDEGYYWSALNKERKMKRILKDMQKILNEKLNEENAHKYIIEDKNTIDYHINKENNKMAEKENNKIGD TNGKISIEEDCKNNVKKEIKENINEIIENKNNIVLSNKCSTKPVKIIVDSREKIISRYIYDKADLEFKALDNGDFILSDR VIVERKTAEDLEGSIIDKRLFKQLKDLKKYERPILIVEGNDYFRLSEKIINGTMVSIMLDFNIPVIFTKDMEETANILIK MAEREQLRDKRTISIRTGKKPMSLKERQRFIVESFPDIGALMAENLLIKFGTIENIVKASVEELREVEGIGEITAKKIKS VLTEKYEK
Sequences:
>Translated_808_residues MNITHPLIKPNTMEARIYQQTMVANALRKNTLCVLGTGLGKTAIATLTIAGILSKNNNKNINKKVLIIAPSRPLVEQHYN SLKTFLNIPEDKIVVLTGKIAPAKRQKIWEEGKIFIATPQIVENDIVANRVNTDDFALLIADEAHHTTGNHSYSFVASVF RNKSHILGLTASPGSNIEKILEVCKNLGIEHVEIRTIDDIDVKEYVQTVKLRPIKVELPKEFAECINLLKQAQMERLKIL RDHKIIYSTNVNKTELLQLQKRIMVIEDNSKYELIKIASEAIKLDYAIETLECQGKEAFLNYYERLSSQDTKSAKAIIKD SKVLKVAYSLRTTELEHPKTEKLLEVVNDVLNKEEGKKEKKNTKKKNTNNTNNIDNNNKTIIFAQYRDTVEKIVNLLNSN GIQAIPFVGQSNKDGKGMSQKKQIEAVEKFKNDPAVNVLVSTSVSEEGIDIMSVNFVIFYEPVPSEIRFIQRRGRASRGE GGECIVLITKDSRDEGYYWSALNKERKMKRILKDMQKILNEKLNEENAHKYIIEDKNTIDYHINKENNKMAEKENNKIGD TNGKISIEEDCKNNVKKEIKENINEIIENKNNIVLSNKCSTKPVKIIVDSREKIISRYIYDKADLEFKALDNGDFILSDR VIVERKTAEDLEGSIIDKRLFKQLKDLKKYERPILIVEGNDYFRLSEKIINGTMVSIMLDFNIPVIFTKDMEETANILIK MAEREQLRDKRTISIRTGKKPMSLKERQRFIVESFPDIGALMAENLLIKFGTIENIVKASVEELREVEGIGEITAKKIKS VLTEKYEK >Mature_808_residues MNITHPLIKPNTMEARIYQQTMVANALRKNTLCVLGTGLGKTAIATLTIAGILSKNNNKNINKKVLIIAPSRPLVEQHYN SLKTFLNIPEDKIVVLTGKIAPAKRQKIWEEGKIFIATPQIVENDIVANRVNTDDFALLIADEAHHTTGNHSYSFVASVF RNKSHILGLTASPGSNIEKILEVCKNLGIEHVEIRTIDDIDVKEYVQTVKLRPIKVELPKEFAECINLLKQAQMERLKIL RDHKIIYSTNVNKTELLQLQKRIMVIEDNSKYELIKIASEAIKLDYAIETLECQGKEAFLNYYERLSSQDTKSAKAIIKD SKVLKVAYSLRTTELEHPKTEKLLEVVNDVLNKEEGKKEKKNTKKKNTNNTNNIDNNNKTIIFAQYRDTVEKIVNLLNSN GIQAIPFVGQSNKDGKGMSQKKQIEAVEKFKNDPAVNVLVSTSVSEEGIDIMSVNFVIFYEPVPSEIRFIQRRGRASRGE GGECIVLITKDSRDEGYYWSALNKERKMKRILKDMQKILNEKLNEENAHKYIIEDKNTIDYHINKENNKMAEKENNKIGD TNGKISIEEDCKNNVKKEIKENINEIIENKNNIVLSNKCSTKPVKIIVDSREKIISRYIYDKADLEFKALDNGDFILSDR VIVERKTAEDLEGSIIDKRLFKQLKDLKKYERPILIVEGNDYFRLSEKIINGTMVSIMLDFNIPVIFTKDMEETANILIK MAEREQLRDKRTISIRTGKKPMSLKERQRFIVESFPDIGALMAENLLIKFGTIENIVKASVEELREVEGIGEITAKKIKS VLTEKYEK
Specific function: RNA-Dependent ATPase Activity. Suppressor Of A Mutant Defective In 50s Ribosomal Subunit Assembly. Probably Interacts With 23s Ribosomal RNA. [C]
COG id: COG1111
COG function: function code L; ERCC4-like helicases
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 helicase C-terminal domain [H]
Homologues:
Organism=Homo sapiens, GI74959747, Length=569, Percent_Identity=28.4710017574692, Blast_Score=192, Evalue=2e-48, Organism=Homo sapiens, GI27881482, Length=621, Percent_Identity=22.2222222222222, Blast_Score=99, Evalue=2e-20, Organism=Saccharomyces cerevisiae, GI6322192, Length=563, Percent_Identity=26.2877442273535, Blast_Score=164, Evalue=4e-41, Organism=Drosophila melanogaster, GI116008407, Length=518, Percent_Identity=29.7297297297297, Blast_Score=201, Evalue=2e-51,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR014001 - InterPro: IPR011545 - InterPro: IPR020819 - InterPro: IPR006166 - InterPro: IPR001650 - InterPro: IPR014021 - InterPro: IPR000445 - InterPro: IPR003583 - InterPro: IPR011335 - InterPro: IPR010994 [H]
Pfam domain/function: PF00270 DEAD; PF02732 ERCC4; PF00271 Helicase_C; PF00633 HHH [H]
EC number: =3.6.4.13 [H]
Molecular weight: Translated: 92344; Mature: 92344
Theoretical pI: Translated: 9.44; Mature: 9.44
Prosite motif: PS00152 ATPASE_ALPHA_BETA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.9 %Cys (Translated Protein) 2.0 %Met (Translated Protein) 2.8 %Cys+Met (Translated Protein) 0.9 %Cys (Mature Protein) 2.0 %Met (Mature Protein) 2.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNITHPLIKPNTMEARIYQQTMVANALRKNTLCVLGTGLGKTAIATLTIAGILSKNNNKN CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCC INKKVLIIAPSRPLVEQHYNSLKTFLNIPEDKIVVLTGKIAPAKRQKIWEEGKIFIATPQ CCEEEEEEECCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHCCCEEEECCH IVENDIVANRVNTDDFALLIADEAHHTTGNHSYSFVASVFRNKSHILGLTASPGSNIEKI HHHCCHHHCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCHHHH LEVCKNLGIEHVEIRTIDDIDVKEYVQTVKLRPIKVELPKEFAECINLLKQAQMERLKIL HHHHHHCCCCEEEEEEECCCCHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHHHHHHH RDHKIIYSTNVNKTELLQLQKRIMVIEDNSKYELIKIASEAIKLDYAIETLECQGKEAFL HCCEEEEECCCCHHHHHHHHHCEEEEECCCCEEHHHHHHHHHHHHEEEEEEECCCHHHHH NYYERLSSQDTKSAKAIIKDSKVLKVAYSLRTTELEHPKTEKLLEVVNDVLNKEEGKKEK HHHHHHCCCCCHHHHHHHCCCCEEEEEEHHHHCCCCCCCHHHHHHHHHHHHCCCCCCHHH KNTKKKNTNNTNNIDNNNKTIIFAQYRDTVEKIVNLLNSNGIQAIPFVGQSNKDGKGMSQ HHCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCH KKQIEAVEKFKNDPAVNVLVSTSVSEEGIDIMSVNFVIFYEPVPSEIRFIQRRGRASRGE HHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEEEEEEEEECCCCHHHHHHHHCCCCCCCC GGECIVLITKDSRDEGYYWSALNKERKMKRILKDMQKILNEKLNEENAHKYIIEDKNTID CCCEEEEEEECCCCCCEEEHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCEEE YHINKENNKMAEKENNKIGDTNGKISIEEDCKNNVKKEIKENINEIIENKNNIVLSNKCS EEEECCCCCHHHHCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCC TKPVKIIVDSREKIISRYIYDKADLEFKALDNGDFILSDRVIVERKTAEDLEGSIIDKRL CCCEEEEECCHHHHHHHHHHCCCCCEEEEECCCCEEEECCEEEEECCHHHHCHHHHHHHH FKQLKDLKKYERPILIVEGNDYFRLSEKIINGTMVSIMLDFNIPVIFTKDMEETANILIK HHHHHHHHHHCCCEEEEECCCEEEHHHHHHCCEEEEEEEECCCCEEEECCHHHHHHHHHH MAEREQLRDKRTISIRTGKKPMSLKERQRFIVESFPDIGALMAENLLIKFGTIENIVKAS HHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHHEEEECCHHHHHHHH VEELREVEGIGEITAKKIKSVLTEKYEK HHHHHHHHCCHHHHHHHHHHHHHHHCCC >Mature Secondary Structure MNITHPLIKPNTMEARIYQQTMVANALRKNTLCVLGTGLGKTAIATLTIAGILSKNNNKN CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCC INKKVLIIAPSRPLVEQHYNSLKTFLNIPEDKIVVLTGKIAPAKRQKIWEEGKIFIATPQ CCEEEEEEECCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHCCCEEEECCH IVENDIVANRVNTDDFALLIADEAHHTTGNHSYSFVASVFRNKSHILGLTASPGSNIEKI HHHCCHHHCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCHHHH LEVCKNLGIEHVEIRTIDDIDVKEYVQTVKLRPIKVELPKEFAECINLLKQAQMERLKIL HHHHHHCCCCEEEEEEECCCCHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHHHHHHH RDHKIIYSTNVNKTELLQLQKRIMVIEDNSKYELIKIASEAIKLDYAIETLECQGKEAFL HCCEEEEECCCCHHHHHHHHHCEEEEECCCCEEHHHHHHHHHHHHEEEEEEECCCHHHHH NYYERLSSQDTKSAKAIIKDSKVLKVAYSLRTTELEHPKTEKLLEVVNDVLNKEEGKKEK HHHHHHCCCCCHHHHHHHCCCCEEEEEEHHHHCCCCCCCHHHHHHHHHHHHCCCCCCHHH KNTKKKNTNNTNNIDNNNKTIIFAQYRDTVEKIVNLLNSNGIQAIPFVGQSNKDGKGMSQ HHCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCH KKQIEAVEKFKNDPAVNVLVSTSVSEEGIDIMSVNFVIFYEPVPSEIRFIQRRGRASRGE HHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEEEEEEEEECCCCHHHHHHHHCCCCCCCC GGECIVLITKDSRDEGYYWSALNKERKMKRILKDMQKILNEKLNEENAHKYIIEDKNTID CCCEEEEEEECCCCCCEEEHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCEEE YHINKENNKMAEKENNKIGDTNGKISIEEDCKNNVKKEIKENINEIIENKNNIVLSNKCS EEEECCCCCHHHHCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCC TKPVKIIVDSREKIISRYIYDKADLEFKALDNGDFILSDRVIVERKTAEDLEGSIIDKRL CCCEEEEECCHHHHHHHHHHCCCCCEEEEECCCCEEEECCEEEEECCHHHHCHHHHHHHH FKQLKDLKKYERPILIVEGNDYFRLSEKIINGTMVSIMLDFNIPVIFTKDMEETANILIK HHHHHHHHHHCCCEEEEECCCEEEHHHHHHCCEEEEEEEECCCCEEEECCHHHHHHHHHH MAEREQLRDKRTISIRTGKKPMSLKERQRFIVESFPDIGALMAENLLIKFGTIENIVKAS HHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHHEEEECCHHHHHHHH VEELREVEGIGEITAKKIKSVLTEKYEK HHHHHHHHCCHHHHHHHHHHHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 8688087 [H]