Click here to switch to the map view.

The map label for this gene is ndk [H]

Identifier: 150400540

GI number: 150400540

Start: 109610

End: 110005

Strand: Reverse

Name: ndk [H]

Synonym: Maeo_0102

Alternate gene names: 150400540

Gene position: 110005-109610 (Counterclockwise)

Preceding gene: 150400543

Following gene: 150400539

Centisome position: 7.01

GC content: 31.57

Gene sequence:

>396_bases
ATGGAACAAACATTGGTATTACTAAAACCAGATTCAGTCGAAAGAAAACTAATAGGTAAAATCATTCAACGATTTGAGAA
TAAAAACTTTAATATTACAAATTTAAAAATGATTACTATGAATCGGGAACTCGCGGAAAAACATTATGAGGAACATCGTG
GAAGAGATTATTTTGATAAAATTGTATCATTTATGTGTTCTGGAAGAATTGTGGCAATGGTAATAGAGGGAGAAGGAGTT
ATAAAATCTGTTAGAAAAATGGTGGGAAAAACCAATCCATTGGAAGCAGAAGCAGGAACTATAAGGGGAGATTATGGATA
TACCACACCGGCAAATTTAATACATTCTTCAGATTCGGAAGAAAGTGCTAAAAGGGAAATAAATTTATTTTTTTAG

Upstream 100 bases:

>100_bases
ATATAATATTAGATAAATAAAATACAAATATTAAATGGAAAAATACCTACCAATTTCAAAAAAAATTAAAGAAAATTATC
AAATATTAACAGGGGTTAAT

Downstream 100 bases:

>100_bases
AAAATTAATTTTATATATTATTTTTTTAGAATCTTACTCATGGATAAACAGTTGTCCGCTAAAGTCTATAAATATATTCT
TTTGGCATATTAGAATAAAC

Product: nucleoside diphosphate kinase

Products: NA

Alternate protein names: NDK; NDP kinase; Nucleoside-2-P kinase [H]

Number of amino acids: Translated: 131; Mature: 131

Protein sequence:

>131_residues
MEQTLVLLKPDSVERKLIGKIIQRFENKNFNITNLKMITMNRELAEKHYEEHRGRDYFDKIVSFMCSGRIVAMVIEGEGV
IKSVRKMVGKTNPLEAEAGTIRGDYGYTTPANLIHSSDSEESAKREINLFF

Sequences:

>Translated_131_residues
MEQTLVLLKPDSVERKLIGKIIQRFENKNFNITNLKMITMNRELAEKHYEEHRGRDYFDKIVSFMCSGRIVAMVIEGEGV
IKSVRKMVGKTNPLEAEAGTIRGDYGYTTPANLIHSSDSEESAKREINLFF
>Mature_131_residues
MEQTLVLLKPDSVERKLIGKIIQRFENKNFNITNLKMITMNRELAEKHYEEHRGRDYFDKIVSFMCSGRIVAMVIEGEGV
IKSVRKMVGKTNPLEAEAGTIRGDYGYTTPANLIHSSDSEESAKREINLFF

Specific function: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate [H]

COG id: COG0105

COG function: function code F; Nucleoside diphosphate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NDK family [H]

Homologues:

Organism=Homo sapiens, GI37693993, Length=130, Percent_Identity=46.9230769230769, Blast_Score=138, Evalue=1e-33,
Organism=Homo sapiens, GI4826862, Length=130, Percent_Identity=43.8461538461538, Blast_Score=132, Evalue=8e-32,
Organism=Homo sapiens, GI38045913, Length=130, Percent_Identity=46.1538461538462, Blast_Score=130, Evalue=4e-31,
Organism=Homo sapiens, GI4557797, Length=130, Percent_Identity=46.1538461538462, Blast_Score=130, Evalue=4e-31,
Organism=Homo sapiens, GI66392203, Length=131, Percent_Identity=44.2748091603053, Blast_Score=126, Evalue=4e-30,
Organism=Homo sapiens, GI66392227, Length=131, Percent_Identity=44.2748091603053, Blast_Score=126, Evalue=5e-30,
Organism=Homo sapiens, GI66392205, Length=131, Percent_Identity=44.2748091603053, Blast_Score=126, Evalue=5e-30,
Organism=Homo sapiens, GI4505409, Length=131, Percent_Identity=44.2748091603053, Blast_Score=126, Evalue=5e-30,
Organism=Homo sapiens, GI66392192, Length=131, Percent_Identity=44.2748091603053, Blast_Score=126, Evalue=5e-30,
Organism=Homo sapiens, GI5031951, Length=135, Percent_Identity=34.8148148148148, Blast_Score=85, Evalue=2e-17,
Organism=Homo sapiens, GI37574614, Length=133, Percent_Identity=33.8345864661654, Blast_Score=80, Evalue=6e-16,
Organism=Homo sapiens, GI7019465, Length=133, Percent_Identity=33.8345864661654, Blast_Score=80, Evalue=6e-16,
Organism=Homo sapiens, GI30023828, Length=135, Percent_Identity=31.1111111111111, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1788866, Length=131, Percent_Identity=45.0381679389313, Blast_Score=121, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17506807, Length=130, Percent_Identity=43.0769230769231, Blast_Score=124, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI71995094, Length=130, Percent_Identity=27.6923076923077, Blast_Score=64, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322783, Length=130, Percent_Identity=46.9230769230769, Blast_Score=136, Evalue=1e-33,
Organism=Drosophila melanogaster, GI45549037, Length=130, Percent_Identity=47.6923076923077, Blast_Score=136, Evalue=4e-33,
Organism=Drosophila melanogaster, GI18860097, Length=134, Percent_Identity=35.0746268656716, Blast_Score=92, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001564
- InterPro:   IPR023005 [H]

Pfam domain/function: PF00334 NDK [H]

EC number: =2.7.4.6 [H]

Molecular weight: Translated: 15029; Mature: 15029

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQTLVLLKPDSVERKLIGKIIQRFENKNFNITNLKMITMNRELAEKHYEEHRGRDYFDK
CCCCEEEECCCCHHHHHHHHHHHHHCCCCCCEEEEEEEECCHHHHHHHHHHHCCCHHHHH
IVSFMCSGRIVAMVIEGEGVIKSVRKMVGKTNPLEAEAGTIRGDYGYTTPANLIHSSDSE
HHHHHHCCCEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCEECCCCCCCHHHHHCCCCCH
ESAKREINLFF
HHHHHEEEECC
>Mature Secondary Structure
MEQTLVLLKPDSVERKLIGKIIQRFENKNFNITNLKMITMNRELAEKHYEEHRGRDYFDK
CCCCEEEECCCCHHHHHHHHHHHHHCCCCCCEEEEEEEECCHHHHHHHHHHHCCCHHHHH
IVSFMCSGRIVAMVIEGEGVIKSVRKMVGKTNPLEAEAGTIRGDYGYTTPANLIHSSDSE
HHHHHHCCCEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCEECCCCCCCHHHHHCCCCCH
ESAKREINLFF
HHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087; 11053861 [H]