Click here to switch to the map view.

The map label for this gene is fwdA [H]

Identifier: 150400521

GI number: 150400521

Start: 84860

End: 86653

Strand: Direct

Name: fwdA [H]

Synonym: Maeo_0083

Alternate gene names: 150400521

Gene position: 84860-86653 (Clockwise)

Preceding gene: 150400520

Following gene: 150400522

Centisome position: 5.41

GC content: 35.79

Gene sequence:

>1794_bases
ATGAACCTTATTATAAAGAATGGATTCGTTTTTGACCCATTAAATAAAATAGACGGGGAAAAAATGGATATATTTGTAAA
AAATGGAAAAATCGTTCAATCGCTTTCCCCGGGCGAAAAAAAGAAAGCAAAAATAATAGATGCGACCAATAAAACCATAA
TGCCGGGGGGCGTAGATTCTCACACACATATTGCAGGGGCAAAAGTAACCACTGGAAGAATGATGTGCCCGGAGCTCCAA
TATGATACCCCAATAAGTAAAACAGAAAATACTCATTGTGGTAGTGGAAATATCGTTCCATCGTCATATATTATAGGATA
TAAATATGCCTCTATGGGATATACTTCACTTTTTGAACCAGCCATACCTCCAATGTTGGCCAGACATACCCACGAAGAGC
TATACCACATTCCAATAGTTGACAAAGCGGGCTACCTATTACTTGGAAACAACTGGTTTGTAATGAAATATTTAAAAGAA
GGGGACATCGATAAAGCAGCAGCTTATGTTGGTTGGATGTTAAACACCCATAAAGCATATGGTATTAAATGTGTAAATCC
TGCAGGAGTAGAAAACTGGGGTTGGGGTATGGATGTGAGCTCTCTAGACGAAGCAAATATTCATTTTGAAGTAACCCCAA
GGGAAGTAATTGAAGGACTTTGTGAAGTTAATGAAATATTGGGTTGCCCAATGTCAATGCATCTTCATGCCAACAATCTT
GGACACCCCGGAAACTGGGAAATAACAAGAGATTCATTAGAAATTCCAAAAAATGTGGGGGTAACTTCAAAGAAGCATAA
TTCAAAAAAGAATATGGTTAATTTGGATAGTAAAAATAATGAAATTGAATTGGAAAAAACAAAAATAGAATGGGAAAGAA
ATCAAAGCATATATATGACACATGTTCAATTCAATGCATTTGGGGGAACTTCGTGGAAGGATTTTGAATCTGGAACAAAA
GGAATCATTGACTATGTAAATAAATCAAAACATGCCATTATTGATAGTGGCTGTGTAGTATTTGGTCAAACTATTTGTAT
GACTGGGGATGGTCCGTCAATATATGGATTAGGGGCATTAACAGGAGGAAAATGGACAAACTGTGATGTAGAATTAGAAT
GTGGTTCTGGTATTGCGCCCATGAATTATAAAAAGAAAAATGGAGTTCATGCAACCCAATGGGCAATGGGATTGGAATTA
ATATTGGGTATAGATGACCCATGGAAAGTTATAATGACAACAGATAGTCCAAATGGTGGTTGTTTTGTTCATTATCCCAA
AATTATAGCTTGGTTAATGTCTAAAAAAGGAAGGGAAAACACATTAAATGAAGTCCATAAATGGGCATCAGATAGAACAG
ACCTTCCGGGAATGGATAGGGAAATGTCATTATATGATATAGCCACAGTTACAAGGGCAACAGCCGCAAAATGTGTTGGA
CTTGCACATAAAAAAGGACATCTTGGAGTTGGAGCCGATGCAGATATTGCAATATATGACATAAATCCAAATACACTTGA
TGTAAATGATTATGATGGCATTGTAAATAAATTCTCATGCACAGAATATACCATAAAAGGCGGTGTAATTGTATCCAAAG
GAGATAAAATTGTAGATGCTTCAAATGGAACAACAAGATTTTGTAATGTGTCGTTGCCTGATGAACAGGTATATCAAGAT
GTATTTAAGGACATAGAATCTTGGTTTAAGAAATACTACTCACTTAGGCTAAAAAACTATCCTACAACGAATAAATATCT
TACAAATCCAGAAGCTGTAAATATAGGTGAATAA

Upstream 100 bases:

>100_bases
GTATTATTTAATAAATTATATGATTTGAATTATGTGTATTTTTATATCGGTATATGTTAATATAAATTAATATGTATTGG
TATATCGTGTAGGTGATGTT

Downstream 100 bases:

>100_bases
TATGGATATAATATTAACTCCAACCAAAAAACCAGACATATCAATTGAGGCAGATGTTATTTCTCCCGATTATTTTGCAG
GTAAAACCATAGACGAAATT

Product: amidohydrolase 3

Products: CO2; methanofuran; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 597; Mature: 597

Protein sequence:

>597_residues
MNLIIKNGFVFDPLNKIDGEKMDIFVKNGKIVQSLSPGEKKKAKIIDATNKTIMPGGVDSHTHIAGAKVTTGRMMCPELQ
YDTPISKTENTHCGSGNIVPSSYIIGYKYASMGYTSLFEPAIPPMLARHTHEELYHIPIVDKAGYLLLGNNWFVMKYLKE
GDIDKAAAYVGWMLNTHKAYGIKCVNPAGVENWGWGMDVSSLDEANIHFEVTPREVIEGLCEVNEILGCPMSMHLHANNL
GHPGNWEITRDSLEIPKNVGVTSKKHNSKKNMVNLDSKNNEIELEKTKIEWERNQSIYMTHVQFNAFGGTSWKDFESGTK
GIIDYVNKSKHAIIDSGCVVFGQTICMTGDGPSIYGLGALTGGKWTNCDVELECGSGIAPMNYKKKNGVHATQWAMGLEL
ILGIDDPWKVIMTTDSPNGGCFVHYPKIIAWLMSKKGRENTLNEVHKWASDRTDLPGMDREMSLYDIATVTRATAAKCVG
LAHKKGHLGVGADADIAIYDINPNTLDVNDYDGIVNKFSCTEYTIKGGVIVSKGDKIVDASNGTTRFCNVSLPDEQVYQD
VFKDIESWFKKYYSLRLKNYPTTNKYLTNPEAVNIGE

Sequences:

>Translated_597_residues
MNLIIKNGFVFDPLNKIDGEKMDIFVKNGKIVQSLSPGEKKKAKIIDATNKTIMPGGVDSHTHIAGAKVTTGRMMCPELQ
YDTPISKTENTHCGSGNIVPSSYIIGYKYASMGYTSLFEPAIPPMLARHTHEELYHIPIVDKAGYLLLGNNWFVMKYLKE
GDIDKAAAYVGWMLNTHKAYGIKCVNPAGVENWGWGMDVSSLDEANIHFEVTPREVIEGLCEVNEILGCPMSMHLHANNL
GHPGNWEITRDSLEIPKNVGVTSKKHNSKKNMVNLDSKNNEIELEKTKIEWERNQSIYMTHVQFNAFGGTSWKDFESGTK
GIIDYVNKSKHAIIDSGCVVFGQTICMTGDGPSIYGLGALTGGKWTNCDVELECGSGIAPMNYKKKNGVHATQWAMGLEL
ILGIDDPWKVIMTTDSPNGGCFVHYPKIIAWLMSKKGRENTLNEVHKWASDRTDLPGMDREMSLYDIATVTRATAAKCVG
LAHKKGHLGVGADADIAIYDINPNTLDVNDYDGIVNKFSCTEYTIKGGVIVSKGDKIVDASNGTTRFCNVSLPDEQVYQD
VFKDIESWFKKYYSLRLKNYPTTNKYLTNPEAVNIGE
>Mature_597_residues
MNLIIKNGFVFDPLNKIDGEKMDIFVKNGKIVQSLSPGEKKKAKIIDATNKTIMPGGVDSHTHIAGAKVTTGRMMCPELQ
YDTPISKTENTHCGSGNIVPSSYIIGYKYASMGYTSLFEPAIPPMLARHTHEELYHIPIVDKAGYLLLGNNWFVMKYLKE
GDIDKAAAYVGWMLNTHKAYGIKCVNPAGVENWGWGMDVSSLDEANIHFEVTPREVIEGLCEVNEILGCPMSMHLHANNL
GHPGNWEITRDSLEIPKNVGVTSKKHNSKKNMVNLDSKNNEIELEKTKIEWERNQSIYMTHVQFNAFGGTSWKDFESGTK
GIIDYVNKSKHAIIDSGCVVFGQTICMTGDGPSIYGLGALTGGKWTNCDVELECGSGIAPMNYKKKNGVHATQWAMGLEL
ILGIDDPWKVIMTTDSPNGGCFVHYPKIIAWLMSKKGRENTLNEVHKWASDRTDLPGMDREMSLYDIATVTRATAAKCVG
LAHKKGHLGVGADADIAIYDINPNTLDVNDYDGIVNKFSCTEYTIKGGVIVSKGDKIVDASNGTTRFCNVSLPDEQVYQD
VFKDIESWFKKYYSLRLKNYPTTNKYLTNPEAVNIGE

Specific function: Unknown

COG id: COG1229

COG function: function code C; Formylmethanofuran dehydrogenase subunit A

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013108
- InterPro:   IPR012027
- InterPro:   IPR011059 [H]

Pfam domain/function: PF07969 Amidohydro_3 [H]

EC number: 1.2.99.5

Molecular weight: Translated: 66167; Mature: 66167

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: PS00211 ABC_TRANSPORTER_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLIIKNGFVFDPLNKIDGEKMDIFVKNGKIVQSLSPGEKKKAKIIDATNKTIMPGGVDS
CEEEEECCEEECCHHHCCCCEEEEEEECCEEEECCCCCCCCCEEEEECCCCEECCCCCCC
HTHIAGAKVTTGRMMCPELQYDTPISKTENTHCGSGNIVPSSYIIGYKYASMGYTSLFEP
CCEECCCEEECCCEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCHHHHCC
AIPPMLARHTHEELYHIPIVDKAGYLLLGNNWFVMKYLKEGDIDKAAAYVGWMLNTHKAY
CCCHHHHHCCHHHEEEEEEECCCCEEEECCCEEEEEEECCCCCHHHHHHHHHHEECCCCC
GIKCVNPAGVENWGWGMDVSSLDEANIHFEVTPREVIEGLCEVNEILGCPMSMHLHANNL
CEEECCCCCCCCCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHCCCEEEEEEECCC
GHPGNWEITRDSLEIPKNVGVTSKKHNSKKNMVNLDSKNNEIELEKTKIEWERNQSIYMT
CCCCCCEEECCCCCCCCCCCCCCCCCCCCCCEEEECCCCCEEEEEEEEEEEECCCEEEEE
HVQFNAFGGTSWKDFESGTKGIIDYVNKSKHAIIDSGCVVFGQTICMTGDGPSIYGLGAL
EEEEEECCCCCCHHHHCCCHHHHHHHCCCCEEEEECCCEEECCEEEEECCCCCEEEEEEE
TGGKWTNCDVELECGSGIAPMNYKKKNGVHATQWAMGLELILGIDDPWKVIMTTDSPNGG
CCCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHCCEEEEEECCCCCEEEEEECCCCCC
CFVHYPKIIAWLMSKKGRENTLNEVHKWASDRTDLPGMDREMSLYDIATVTRATAAKCVG
EEEEHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHH
LAHKKGHLGVGADADIAIYDINPNTLDVNDYDGIVNKFSCTEYTIKGGVIVSKGDKIVDA
HHCCCCCCCCCCCCCEEEEECCCCEEECCCCCCHHCEEECCEEEEECCEEEECCCEEEEC
SNGTTRFCNVSLPDEQVYQDVFKDIESWFKKYYSLRLKNYPTTNKYLTNPEAVNIGE
CCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCEECCCCEEECCC
>Mature Secondary Structure
MNLIIKNGFVFDPLNKIDGEKMDIFVKNGKIVQSLSPGEKKKAKIIDATNKTIMPGGVDS
CEEEEECCEEECCHHHCCCCEEEEEEECCEEEECCCCCCCCCEEEEECCCCEECCCCCCC
HTHIAGAKVTTGRMMCPELQYDTPISKTENTHCGSGNIVPSSYIIGYKYASMGYTSLFEP
CCEECCCEEECCCEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCHHHHCC
AIPPMLARHTHEELYHIPIVDKAGYLLLGNNWFVMKYLKEGDIDKAAAYVGWMLNTHKAY
CCCHHHHHCCHHHEEEEEEECCCCEEEECCCEEEEEEECCCCCHHHHHHHHHHEECCCCC
GIKCVNPAGVENWGWGMDVSSLDEANIHFEVTPREVIEGLCEVNEILGCPMSMHLHANNL
CEEECCCCCCCCCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHCCCEEEEEEECCC
GHPGNWEITRDSLEIPKNVGVTSKKHNSKKNMVNLDSKNNEIELEKTKIEWERNQSIYMT
CCCCCCEEECCCCCCCCCCCCCCCCCCCCCCEEEECCCCCEEEEEEEEEEEECCCEEEEE
HVQFNAFGGTSWKDFESGTKGIIDYVNKSKHAIIDSGCVVFGQTICMTGDGPSIYGLGAL
EEEEEECCCCCCHHHHCCCHHHHHHHCCCCEEEEECCCEEECCEEEEECCCCCEEEEEEE
TGGKWTNCDVELECGSGIAPMNYKKKNGVHATQWAMGLELILGIDDPWKVIMTTDSPNGG
CCCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHCCEEEEEECCCCCEEEEEECCCCCC
CFVHYPKIIAWLMSKKGRENTLNEVHKWASDRTDLPGMDREMSLYDIATVTRATAAKCVG
EEEEHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHH
LAHKKGHLGVGADADIAIYDINPNTLDVNDYDGIVNKFSCTEYTIKGGVIVSKGDKIVDA
HHCCCCCCCCCCCCCEEEEECCCCEEECCCCCCHHCEEECCEEEEECCEEEECCCEEEEC
SNGTTRFCNVSLPDEQVYQDVFKDIESWFKKYYSLRLKNYPTTNKYLTNPEAVNIGE
CCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCEECCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: formylmethanofuran; H2O; acceptor

Specific reaction: formylmethanofuran + H2O + acceptor = CO2 + methanofuran + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]