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The map label for this gene is atpA

Identifier: 150400503

GI number: 150400503

Start: 71153

End: 72913

Strand: Direct

Name: atpA

Synonym: Maeo_0065

Alternate gene names: 150400503

Gene position: 71153-72913 (Clockwise)

Preceding gene: 150400502

Following gene: 150400504

Centisome position: 4.53

GC content: 38.05

Gene sequence:

>1761_bases
ATGGTATCAGGTAAAATTGTAAAAATAGCAGGTCCTGTTGTTGTTGCCGAAGGAATGAAAGGAGCTCAAATGTATGAAGT
TGTTAAAGTAGGGAACGAAGGATTAACAGGAGAAATTATCCAGTTAGAATCAGATAAAGCAGTTATTCAGGTATATGAAG
AAACCGCAGGTATTGTTCCAGGGGAGCCAGTTGAAGGGACAGGAGCTCCATTATCCGCAGAGCTTGGACCCGGTATGTTA
AAGGCAATGTATGATGGTATTCAAAGACCATTAACAGCTATTGAAGATGCTACAAAAAGTATTTACATCCCAAGAGGGGT
TAGCGTTCCATCAATATCCCGAGAAGCAAAATGGGACTTTACACCAACTGTAAATGTTGGAGATAAAGTTGAGGCAGGAG
ACATCATTGGAACTGTTCCAGAAACAAAATCAATTGTTCATAAAATAATGATTCCAAATGGGATAAGCGGAACAATTAAA
GAAATAAAATCCGGTAGTTTCACAGTTGTAGAACCAATTGCAATAGTAGAAACAGAAAACGGGGAAGAAAAAGAAATCAT
AATGATGCAAAAATGGCCTGTTAGAAATCCAAGACCATACAAAGAAAAATTACCTCCTGAAATTCCATTAGTTACAGGAC
AAAGATTAGAAGATACATTCTTTGGTTTGGCAAAAGGTGGTGCATCTGCAATTCCAGGACCATTCGGAAGTGGTAAAACA
GTTACACAACACCAGTTGGCAAAATGGTCAGATGCTGATATTGTTGTATATATTGGATGTGGAGAAAGAGGAAACGAGAT
GACGGAAGTTATTGAAGAATTCCCGCACCTTGATGACCTTAAAACAGGAAATAAATTAATGGACAGAACTGTATTAATTG
CTAACACATCAAACATGCCTGTGGCTGCTAGGGAAGCATCAGTATATACTGGTATTACCATTGCAGAATATTTCAGAGAT
ATGGGATACGGTGTTTTATTAACTGCTGATTCCACATCAAGATGGGCAGAGGCAATGAGAGAGATTTCAGGAAGATTGGA
GGAAATGCCAGGGGAAGAAGGATACCCAGCTTACTTGTCTTCAAGATTGGCTCAATTCTACGAAAGAGCAGGAAGAGTTG
CATGTATGGGGCATGACGAAAAACAAGGATTCGTATGTATTGTAGGTGCTGTATCTCCACCCGGAGGGGATTTCTCCGAG
CCAGTTACATCAAACACATTAAGGATTGTAAAGGTGTTCTGGGCATTAGATGCTAATCTCGCAAGAAGAAGACATTTCCC
AGCTATTAACTGGTTGCAAAGTTATTCATTATATCTTGACGATATAGAAGATTGGTGGAAAGAAAACACAGCAGAAGATT
GGAGAGAGATAAGAGACGAAGCTATGAACTTATTGCAAAAAGAAGCAGAATTACAAGAAATTGTTCAGTTAGTTGGTCCC
GATGCACTTCCTGATAAAGAAAGAGTTATTTTGGAAGTATCAAGAATGCTCAGAGAGGATTTCTTACAACAAGATGCTTT
CAGCGATATAGATAGCTACTGTTCTCCTATGAAACAGTACACAATGTTAAAGACAATTATGACATTCTACAGTAAAGCTA
TATTGGCAGTTGAAAAAGGAGCTGACCCAGCAGATATTGCAAAAGTTTCAGTTAAACAGGATGTAGCGAAAATGAAATAT
ACTCCTGAAGAAGAGTTCTTAAATAAATTAGCTCCTGCAATAGTTGAAAAAATTAGTAAAGAATTAGACGCTTTAGTATA
A

Upstream 100 bases:

>100_bases
GACAAAAATGGTGCAATAGTTAGAGAACACGACCCAGTTAAAACTCTTGTAAGAAAAGCCGTAGGTGTAGAACTCAAATA
ATCAAATTACAGGTGAAAAT

Downstream 100 bases:

>100_bases
TTAGATTTATATGAATTAATTATTTATTATAATTAATTTTTAAATTTTTAAAATATTATATTTTACCTATATATTATAAA
TGTTAAAATCATACAAAAAA

Product: V-type ATP synthase subunit A

Products: NA

Alternate protein names: V-ATPase subunit A

Number of amino acids: Translated: 586; Mature: 586

Protein sequence:

>586_residues
MVSGKIVKIAGPVVVAEGMKGAQMYEVVKVGNEGLTGEIIQLESDKAVIQVYEETAGIVPGEPVEGTGAPLSAELGPGML
KAMYDGIQRPLTAIEDATKSIYIPRGVSVPSISREAKWDFTPTVNVGDKVEAGDIIGTVPETKSIVHKIMIPNGISGTIK
EIKSGSFTVVEPIAIVETENGEEKEIIMMQKWPVRNPRPYKEKLPPEIPLVTGQRLEDTFFGLAKGGASAIPGPFGSGKT
VTQHQLAKWSDADIVVYIGCGERGNEMTEVIEEFPHLDDLKTGNKLMDRTVLIANTSNMPVAAREASVYTGITIAEYFRD
MGYGVLLTADSTSRWAEAMREISGRLEEMPGEEGYPAYLSSRLAQFYERAGRVACMGHDEKQGFVCIVGAVSPPGGDFSE
PVTSNTLRIVKVFWALDANLARRRHFPAINWLQSYSLYLDDIEDWWKENTAEDWREIRDEAMNLLQKEAELQEIVQLVGP
DALPDKERVILEVSRMLREDFLQQDAFSDIDSYCSPMKQYTMLKTIMTFYSKAILAVEKGADPADIAKVSVKQDVAKMKY
TPEEEFLNKLAPAIVEKISKELDALV

Sequences:

>Translated_586_residues
MVSGKIVKIAGPVVVAEGMKGAQMYEVVKVGNEGLTGEIIQLESDKAVIQVYEETAGIVPGEPVEGTGAPLSAELGPGML
KAMYDGIQRPLTAIEDATKSIYIPRGVSVPSISREAKWDFTPTVNVGDKVEAGDIIGTVPETKSIVHKIMIPNGISGTIK
EIKSGSFTVVEPIAIVETENGEEKEIIMMQKWPVRNPRPYKEKLPPEIPLVTGQRLEDTFFGLAKGGASAIPGPFGSGKT
VTQHQLAKWSDADIVVYIGCGERGNEMTEVIEEFPHLDDLKTGNKLMDRTVLIANTSNMPVAAREASVYTGITIAEYFRD
MGYGVLLTADSTSRWAEAMREISGRLEEMPGEEGYPAYLSSRLAQFYERAGRVACMGHDEKQGFVCIVGAVSPPGGDFSE
PVTSNTLRIVKVFWALDANLARRRHFPAINWLQSYSLYLDDIEDWWKENTAEDWREIRDEAMNLLQKEAELQEIVQLVGP
DALPDKERVILEVSRMLREDFLQQDAFSDIDSYCSPMKQYTMLKTIMTFYSKAILAVEKGADPADIAKVSVKQDVAKMKY
TPEEEFLNKLAPAIVEKISKELDALV
>Mature_586_residues
MVSGKIVKIAGPVVVAEGMKGAQMYEVVKVGNEGLTGEIIQLESDKAVIQVYEETAGIVPGEPVEGTGAPLSAELGPGML
KAMYDGIQRPLTAIEDATKSIYIPRGVSVPSISREAKWDFTPTVNVGDKVEAGDIIGTVPETKSIVHKIMIPNGISGTIK
EIKSGSFTVVEPIAIVETENGEEKEIIMMQKWPVRNPRPYKEKLPPEIPLVTGQRLEDTFFGLAKGGASAIPGPFGSGKT
VTQHQLAKWSDADIVVYIGCGERGNEMTEVIEEFPHLDDLKTGNKLMDRTVLIANTSNMPVAAREASVYTGITIAEYFRD
MGYGVLLTADSTSRWAEAMREISGRLEEMPGEEGYPAYLSSRLAQFYERAGRVACMGHDEKQGFVCIVGAVSPPGGDFSE
PVTSNTLRIVKVFWALDANLARRRHFPAINWLQSYSLYLDDIEDWWKENTAEDWREIRDEAMNLLQKEAELQEIVQLVGP
DALPDKERVILEVSRMLREDFLQQDAFSDIDSYCSPMKQYTMLKTIMTFYSKAILAVEKGADPADIAKVSVKQDVAKMKY
TPEEEFLNKLAPAIVEKISKELDALV

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit

COG id: COG1155

COG function: function code C; Archaeal/vacuolar-type H+-ATPase subunit A

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI19913424, Length=543, Percent_Identity=54.3278084714549, Blast_Score=599, Evalue=1e-171,
Organism=Homo sapiens, GI32189394, Length=320, Percent_Identity=26.5625, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI19913428, Length=227, Percent_Identity=27.3127753303965, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI19913426, Length=227, Percent_Identity=27.3127753303965, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI50345984, Length=235, Percent_Identity=25.531914893617, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI4757810, Length=235, Percent_Identity=25.531914893617, Blast_Score=72, Evalue=2e-12,
Organism=Escherichia coli, GI1790170, Length=393, Percent_Identity=27.2264631043257, Blast_Score=115, Evalue=9e-27,
Organism=Escherichia coli, GI1788251, Length=235, Percent_Identity=29.7872340425532, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI1790172, Length=242, Percent_Identity=26.4462809917355, Blast_Score=72, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17565854, Length=543, Percent_Identity=54.6961325966851, Blast_Score=603, Evalue=1e-173,
Organism=Caenorhabditis elegans, GI25144756, Length=301, Percent_Identity=28.5714285714286, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17510931, Length=224, Percent_Identity=28.5714285714286, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17570191, Length=227, Percent_Identity=27.3127753303965, Blast_Score=87, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71988080, Length=268, Percent_Identity=25.3731343283582, Blast_Score=76, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI71988063, Length=268, Percent_Identity=25.3731343283582, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI71988074, Length=268, Percent_Identity=25.3731343283582, Blast_Score=75, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6320016, Length=327, Percent_Identity=48.6238532110092, Blast_Score=319, Evalue=6e-88,
Organism=Saccharomyces cerevisiae, GI6322581, Length=348, Percent_Identity=26.7241379310345, Blast_Score=103, Evalue=9e-23,
Organism=Saccharomyces cerevisiae, GI6319603, Length=244, Percent_Identity=27.8688524590164, Blast_Score=86, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6319370, Length=235, Percent_Identity=25.531914893617, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24583988, Length=543, Percent_Identity=54.51197053407, Blast_Score=608, Evalue=1e-174,
Organism=Drosophila melanogaster, GI24583986, Length=543, Percent_Identity=54.51197053407, Blast_Score=608, Evalue=1e-174,
Organism=Drosophila melanogaster, GI24583984, Length=543, Percent_Identity=54.51197053407, Blast_Score=608, Evalue=1e-174,
Organism=Drosophila melanogaster, GI20129479, Length=545, Percent_Identity=53.9449541284404, Blast_Score=604, Evalue=1e-173,
Organism=Drosophila melanogaster, GI24583992, Length=542, Percent_Identity=53.690036900369, Blast_Score=592, Evalue=1e-169,
Organism=Drosophila melanogaster, GI28574560, Length=303, Percent_Identity=29.7029702970297, Blast_Score=105, Evalue=6e-23,
Organism=Drosophila melanogaster, GI24638766, Length=336, Percent_Identity=28.2738095238095, Blast_Score=103, Evalue=5e-22,
Organism=Drosophila melanogaster, GI281361666, Length=227, Percent_Identity=26.431718061674, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24646341, Length=227, Percent_Identity=26.431718061674, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI17136796, Length=227, Percent_Identity=26.431718061674, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24658560, Length=236, Percent_Identity=25.8474576271186, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: 10836 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): VATA_META3 (A6UT35)

Other databases:

- EMBL:   CP000743
- RefSeq:   YP_001324269.1
- ProteinModelPortal:   A6UT35
- SMR:   A6UT35
- STRING:   A6UT35
- GeneID:   5326818
- GenomeReviews:   CP000743_GR
- KEGG:   mae:Maeo_0065
- eggNOG:   arNOG04086
- HOGENOM:   HBG288114
- OMA:   KITWNVI
- ProtClustDB:   PRK04192
- BioCyc:   MAEO419665:MAEO_0065-MONOMER
- HAMAP:   MF_00309
- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005726
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- InterPro:   IPR022878
- TIGRFAMs:   TIGR01043

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 64626; Mature: 64626

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSGKIVKIAGPVVVAEGMKGAQMYEVVKVGNEGLTGEIIQLESDKAVIQVYEETAGIVP
CCCCEEEEEECCEEEECCCCCHHHHHHHHHCCCCCCCEEEEEECCCHHHHEEHHHCCCCC
GEPVEGTGAPLSAELGPGMLKAMYDGIQRPLTAIEDATKSIYIPRGVSVPSISREAKWDF
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCC
TPTVNVGDKVEAGDIIGTVPETKSIVHKIMIPNGISGTIKEIKSGSFTVVEPIAIVETEN
CCCCCCCCCCCCCCEEECCCCHHHHHHHHHCCCCCCHHHHHHCCCCEEEECCEEEEECCC
GEEKEIIMMQKWPVRNPRPYKEKLPPEIPLVTGQRLEDTFFGLAKGGASAIPGPFGSGKT
CCCCEEEEEECCCCCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCC
VTQHQLAKWSDADIVVYIGCGERGNEMTEVIEEFPHLDDLKTGNKLMDRTVLIANTSNMP
HHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCHHHCCEEEEEECCCCC
VAAREASVYTGITIAEYFRDMGYGVLLTADSTSRWAEAMREISGRLEEMPGEEGYPAYLS
EEECCCHHHCCHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
SRLAQFYERAGRVACMGHDEKQGFVCIVGAVSPPGGDFSEPVTSNTLRIVKVFWALDANL
HHHHHHHHHCCCEEEECCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
ARRRHFPAINWLQSYSLYLDDIEDWWKENTAEDWREIRDEAMNLLQKEAELQEIVQLVGP
HHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DALPDKERVILEVSRMLREDFLQQDAFSDIDSYCSPMKQYTMLKTIMTFYSKAILAVEKG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECC
ADPADIAKVSVKQDVAKMKYTPEEEFLNKLAPAIVEKISKELDALV
CCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVSGKIVKIAGPVVVAEGMKGAQMYEVVKVGNEGLTGEIIQLESDKAVIQVYEETAGIVP
CCCCEEEEEECCEEEECCCCCHHHHHHHHHCCCCCCCEEEEEECCCHHHHEEHHHCCCCC
GEPVEGTGAPLSAELGPGMLKAMYDGIQRPLTAIEDATKSIYIPRGVSVPSISREAKWDF
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCC
TPTVNVGDKVEAGDIIGTVPETKSIVHKIMIPNGISGTIKEIKSGSFTVVEPIAIVETEN
CCCCCCCCCCCCCCEEECCCCHHHHHHHHHCCCCCCHHHHHHCCCCEEEECCEEEEECCC
GEEKEIIMMQKWPVRNPRPYKEKLPPEIPLVTGQRLEDTFFGLAKGGASAIPGPFGSGKT
CCCCEEEEEECCCCCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCC
VTQHQLAKWSDADIVVYIGCGERGNEMTEVIEEFPHLDDLKTGNKLMDRTVLIANTSNMP
HHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCHHHCCEEEEEECCCCC
VAAREASVYTGITIAEYFRDMGYGVLLTADSTSRWAEAMREISGRLEEMPGEEGYPAYLS
EEECCCHHHCCHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
SRLAQFYERAGRVACMGHDEKQGFVCIVGAVSPPGGDFSEPVTSNTLRIVKVFWALDANL
HHHHHHHHHCCCEEEECCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
ARRRHFPAINWLQSYSLYLDDIEDWWKENTAEDWREIRDEAMNLLQKEAELQEIVQLVGP
HHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DALPDKERVILEVSRMLREDFLQQDAFSDIDSYCSPMKQYTMLKTIMTFYSKAILAVEKG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECC
ADPADIAKVSVKQDVAKMKYTPEEEFLNKLAPAIVEKISKELDALV
CCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA