BacMap

Definition	Methanococcus aeolicus Nankai-3, complete genome.
Accession	NC_009635
Length	1,569,500

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The map label for this gene is aspC

Identifier: 150400467

GI number: 150400467

Start: 30801

End: 32117

Strand: Direct

Name: aspC

Synonym: Maeo_0028

Alternate gene names: 150400467

Gene position: 30801-32117 (Clockwise)

Preceding gene: 150400466

Following gene: 150400468

Centisome position: 1.96

GC content: 34.4

Gene sequence:

>1317_bases
ATGTATGCATTAGGCGATTGGAGAAGAACACATTATTCATCAGAAGTAAATTCAGAAATGGACGGTCAAGAAATTATAAT
TATGGGCTGGAATCATTCTATAAGAAAATTAGGAAAATTAGTATTTATTATATTGAGAGATAGGGAAGGAACTATACAAA
TAGTAGCACCAAAACAGAAAGTATCAGAAGAAACATTTGCAACGGCGAAATCACTTGGAAAAGAAGATGTAATGGCAATT
AAAGGAAAAGTTGTAGCAAATGAAAAGGCACCTGCTGGATTTGAAGTAATTCCTATTGAAATAAAAATATTAAACAAAGC
AGATACTCCTCTTCCATTGGACCCATCGGAAAAGGTTTCCGCAGATATTGATACAAGATTGGATAAAAGATTTTTAGATT
TAAGAAGACCAAAAATACAATCATTATTTAAATTAAGGTCTGAGGTATTAAAATCTATTAGAAATACTTTTCATGACAAC
GGATTTATTGATGTAGATACCCCAAAACTTGTAGCAAGTGCAACAGAGGGAGGAACAGAATTATTCCCAATATCATACTT
TGATAAAGAGGCGTTTTTAGGACAAAGCCCACAGTTATATAAACAAATGATGATGGCAGCAGGATTTGACAGAGTATTTG
AAATTGGACCAATATTTAGGGCAGAAGAGCACAACACAAGAAGACATTTAAATGAGGCAATCTCAATTGACTGTGAAATG
TCATTTGCAGACGAAAAAGATGCTATGGAAATACTTGAAAAGGTTATTAATAACGCATTTACCGATATCTATAATAATAA
TCAGAAGGAGCTCCAAACACTTGGTATTGATTTAAAAGTTCAAGAAACACCATTCCCAAGAATAGAATATACCGAAGCTG
TTGATATGGTAAATGCAAAAGGTGTTGAAATGGAATGGGGAGAAGACTTCTCCAGACCAGCAGAGGCGGCATTGGGAGAA
ATGATGGATGGATTTTACTTTATAACCGATTGGCCAACTGAAATAAGACCATTTTATACATTGCCAAATGAGGACAACCC
AAAATTATGTAAGGCTTTTGACTTAATGTATAAAGATTTGGAAATATCCTCAGGAGCTCAAAGAAATCATAAATATGATT
TACTTGTGGAGGGAATAAAAAGAATGGGACTTAATCCAGAAGGATTTGGAACATACTTAGAGGCATTTAAATATGGTATG
CCCCCACACTCTGGTTGGGGAGTAGGTATTGAAAGACTTATGATGATTATGGCATGCCAGCAAAATATTAGGGAGTGTGT
TTTATTCCCAAGAGATAGGCAAAGATTAACACCATAA

Upstream 100 bases:

>100_bases
CAAATAAAAAATAATAAATATATAAATAATAAATATATAATACAAATATCAAAATATAAAATTATTATAAAATTATAAAA
ACTAAATAAGGAGATATAAA

Downstream 100 bases:

>100_bases
AAACCAAAACACATAAATGAAATAATAAAAATAATAAATATTAAATTATAAATGAAATAATAAAATTTTGCAAGTGGTGA
ATAATATGGTTTCAAAAGAG

Product: aspartyl-tRNA synthetase

Products: NA

Alternate protein names: Aspartate--tRNA ligase; AspRS

Number of amino acids: Translated: 438; Mature: 438

Protein sequence:

>438_residues
MYALGDWRRTHYSSEVNSEMDGQEIIIMGWNHSIRKLGKLVFIILRDREGTIQIVAPKQKVSEETFATAKSLGKEDVMAI
KGKVVANEKAPAGFEVIPIEIKILNKADTPLPLDPSEKVSADIDTRLDKRFLDLRRPKIQSLFKLRSEVLKSIRNTFHDN
GFIDVDTPKLVASATEGGTELFPISYFDKEAFLGQSPQLYKQMMMAAGFDRVFEIGPIFRAEEHNTRRHLNEAISIDCEM
SFADEKDAMEILEKVINNAFTDIYNNNQKELQTLGIDLKVQETPFPRIEYTEAVDMVNAKGVEMEWGEDFSRPAEAALGE
MMDGFYFITDWPTEIRPFYTLPNEDNPKLCKAFDLMYKDLEISSGAQRNHKYDLLVEGIKRMGLNPEGFGTYLEAFKYGM
PPHSGWGVGIERLMMIMACQQNIRECVLFPRDRQRLTP

Sequences:

>Translated_438_residues
MYALGDWRRTHYSSEVNSEMDGQEIIIMGWNHSIRKLGKLVFIILRDREGTIQIVAPKQKVSEETFATAKSLGKEDVMAI
KGKVVANEKAPAGFEVIPIEIKILNKADTPLPLDPSEKVSADIDTRLDKRFLDLRRPKIQSLFKLRSEVLKSIRNTFHDN
GFIDVDTPKLVASATEGGTELFPISYFDKEAFLGQSPQLYKQMMMAAGFDRVFEIGPIFRAEEHNTRRHLNEAISIDCEM
SFADEKDAMEILEKVINNAFTDIYNNNQKELQTLGIDLKVQETPFPRIEYTEAVDMVNAKGVEMEWGEDFSRPAEAALGE
MMDGFYFITDWPTEIRPFYTLPNEDNPKLCKAFDLMYKDLEISSGAQRNHKYDLLVEGIKRMGLNPEGFGTYLEAFKYGM
PPHSGWGVGIERLMMIMACQQNIRECVLFPRDRQRLTP
>Mature_438_residues
MYALGDWRRTHYSSEVNSEMDGQEIIIMGWNHSIRKLGKLVFIILRDREGTIQIVAPKQKVSEETFATAKSLGKEDVMAI
KGKVVANEKAPAGFEVIPIEIKILNKADTPLPLDPSEKVSADIDTRLDKRFLDLRRPKIQSLFKLRSEVLKSIRNTFHDN
GFIDVDTPKLVASATEGGTELFPISYFDKEAFLGQSPQLYKQMMMAAGFDRVFEIGPIFRAEEHNTRRHLNEAISIDCEM
SFADEKDAMEILEKVINNAFTDIYNNNQKELQTLGIDLKVQETPFPRIEYTEAVDMVNAKGVEMEWGEDFSRPAEAALGE
MMDGFYFITDWPTEIRPFYTLPNEDNPKLCKAFDLMYKDLEISSGAQRNHKYDLLVEGIKRMGLNPEGFGTYLEAFKYGM
PPHSGWGVGIERLMMIMACQQNIRECVLFPRDRQRLTP

Specific function: Unknown

COG id: COG0017

COG function: function code J; Aspartyl/asparaginyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI45439306, Length=435, Percent_Identity=36.0919540229885, Blast_Score=288, Evalue=5e-78,
Organism=Homo sapiens, GI4758762, Length=432, Percent_Identity=29.8611111111111, Blast_Score=198, Evalue=9e-51,
Organism=Homo sapiens, GI226491502, Length=442, Percent_Identity=26.6968325791855, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI194272210, Length=456, Percent_Identity=27.8508771929825, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI5031815, Length=456, Percent_Identity=27.8508771929825, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI40789249, Length=262, Percent_Identity=29.7709923664122, Blast_Score=114, Evalue=2e-25,
Organism=Escherichia coli, GI1787161, Length=387, Percent_Identity=28.6821705426357, Blast_Score=155, Evalue=5e-39,
Organism=Escherichia coli, GI1789256, Length=476, Percent_Identity=27.7310924369748, Blast_Score=155, Evalue=5e-39,
Organism=Escherichia coli, GI1788173, Length=294, Percent_Identity=32.6530612244898, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1790571, Length=477, Percent_Identity=26.8343815513627, Blast_Score=142, Evalue=6e-35,
Organism=Caenorhabditis elegans, GI17551876, Length=458, Percent_Identity=32.9694323144105, Blast_Score=276, Evalue=2e-74,
Organism=Caenorhabditis elegans, GI71984122, Length=426, Percent_Identity=28.6384976525822, Blast_Score=184, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI17556372, Length=408, Percent_Identity=29.1666666666667, Blast_Score=140, Evalue=9e-34,
Organism=Caenorhabditis elegans, GI32566633, Length=298, Percent_Identity=30.2013422818792, Blast_Score=124, Evalue=8e-29,
Organism=Caenorhabditis elegans, GI17535925, Length=461, Percent_Identity=25.8134490238612, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI71994340, Length=461, Percent_Identity=25.8134490238612, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17535927, Length=461, Percent_Identity=25.8134490238612, Blast_Score=112, Evalue=5e-25,
Organism=Saccharomyces cerevisiae, GI6323011, Length=451, Percent_Identity=35.0332594235033, Blast_Score=261, Evalue=1e-70,
Organism=Saccharomyces cerevisiae, GI6321807, Length=433, Percent_Identity=30.9468822170901, Blast_Score=213, Evalue=6e-56,
Organism=Saccharomyces cerevisiae, GI6319872, Length=455, Percent_Identity=26.5934065934066, Blast_Score=135, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6325153, Length=250, Percent_Identity=33.2, Blast_Score=108, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6320242, Length=458, Percent_Identity=24.6724890829694, Blast_Score=100, Evalue=3e-22,
Organism=Drosophila melanogaster, GI17136276, Length=457, Percent_Identity=37.199124726477, Blast_Score=297, Evalue=8e-81,
Organism=Drosophila melanogaster, GI19921528, Length=433, Percent_Identity=29.7921478060046, Blast_Score=183, Evalue=2e-46,
Organism=Drosophila melanogaster, GI19922416, Length=458, Percent_Identity=24.8908296943231, Blast_Score=126, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24640851, Length=461, Percent_Identity=26.8980477223427, Blast_Score=115, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24640849, Length=461, Percent_Identity=26.8980477223427, Blast_Score=115, Evalue=5e-26,
Organism=Drosophila melanogaster, GI24584738, Length=298, Percent_Identity=30.8724832214765, Blast_Score=109, Evalue=4e-24,

Paralogues:

None

Copy number: 80 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): SYD_META3 (A6USZ9)

Other databases:

- EMBL:   CP000743
- RefSeq:   YP_001324233.1
- ProteinModelPortal:   A6USZ9
- SMR:   A6USZ9
- STRING:   A6USZ9
- GeneID:   5326419
- GenomeReviews:   CP000743_GR
- KEGG:   mae:Maeo_0028
- eggNOG:   arNOG04316
- HOGENOM:   HBG745843
- OMA:   TDWPSEI
- ProtClustDB:   PRK05159
- BioCyc:   MAEO419665:MAEO_0028-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00044_A
- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR020780
- InterPro:   IPR004523
- InterPro:   IPR002312
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365
- Gene3D:   G3DSA:2.40.50.140
- PANTHER:   PTHR22594
- PRINTS:   PR01042
- TIGRFAMs:   TIGR00458

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti; SSF50249 Nucleic_acid_OB

EC number: =6.1.1.12

Molecular weight: Translated: 50065; Mature: 50065

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYALGDWRRTHYSSEVNSEMDGQEIIIMGWNHSIRKLGKLVFIILRDREGTIQIVAPKQK
CCCCCCHHHHHCCCHHCCCCCCCEEEEECCCHHHHHHHHEEEEEEECCCCEEEEEECHHH
VSEETFATAKSLGKEDVMAIKGKVVANEKAPAGFEVIPIEIKILNKADTPLPLDPSEKVS
HHHHHHHHHHHCCHHHHHHHCCEEEECCCCCCCEEEEEEEEEEECCCCCCCCCCCCHHHC
ADIDTRLDKRFLDLRRPKIQSLFKLRSEVLKSIRNTFHDNGFIDVDTPKLVASATEGGTE
CCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHEECCCCCCE
LFPISYFDKEAFLGQSPQLYKQMMMAAGFDRVFEIGPIFRAEEHNTRRHLNEAISIDCEM
EEEEEECCHHHHCCCCHHHHHHHHHHHCCHHHHHCCCCEECCCCHHHHHHHHHHEEEEEE
SFADEKDAMEILEKVINNAFTDIYNNNQKELQTLGIDLKVQETPFPRIEYTEAVDMVNAK
CCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCEEEECCCCCCCCCHHHHHHHHCCC
GVEMEWGEDFSRPAEAALGEMMDGFYFITDWPTEIRPFYTLPNEDNPKLCKAFDLMYKDL
CCCEECCCCCCCHHHHHHHHHHCCEEEEECCCCCCCCEEECCCCCCHHHHHHHHHHHHHC
EISSGAQRNHKYDLLVEGIKRMGLNPEGFGTYLEAFKYGMPPHSGWGVGIERLMMIMACQ
CCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
QNIRECVLFPRDRQRLTP
HHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MYALGDWRRTHYSSEVNSEMDGQEIIIMGWNHSIRKLGKLVFIILRDREGTIQIVAPKQK
CCCCCCHHHHHCCCHHCCCCCCCEEEEECCCHHHHHHHHEEEEEEECCCCEEEEEECHHH
VSEETFATAKSLGKEDVMAIKGKVVANEKAPAGFEVIPIEIKILNKADTPLPLDPSEKVS
HHHHHHHHHHHCCHHHHHHHCCEEEECCCCCCCEEEEEEEEEEECCCCCCCCCCCCHHHC
ADIDTRLDKRFLDLRRPKIQSLFKLRSEVLKSIRNTFHDNGFIDVDTPKLVASATEGGTE
CCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHEECCCCCCE
LFPISYFDKEAFLGQSPQLYKQMMMAAGFDRVFEIGPIFRAEEHNTRRHLNEAISIDCEM
EEEEEECCHHHHCCCCHHHHHHHHHHHCCHHHHHCCCCEECCCCHHHHHHHHHHEEEEEE
SFADEKDAMEILEKVINNAFTDIYNNNQKELQTLGIDLKVQETPFPRIEYTEAVDMVNAK
CCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCEEEECCCCCCCCCHHHHHHHHCCC
GVEMEWGEDFSRPAEAALGEMMDGFYFITDWPTEIRPFYTLPNEDNPKLCKAFDLMYKDL
CCCEECCCCCCCHHHHHHHHHHCCEEEEECCCCCCCCEEECCCCCCHHHHHHHHHHHHHC
EISSGAQRNHKYDLLVEGIKRMGLNPEGFGTYLEAFKYGMPPHSGWGVGIERLMMIMACQ
CCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
QNIRECVLFPRDRQRLTP
HHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA