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The map label for this gene is 150400466

Identifier: 150400466

GI number: 150400466

Start: 29701

End: 30714

Strand: Direct

Name: 150400466

Synonym: Maeo_0027

Alternate gene names: NA

Gene position: 29701-30714 (Clockwise)

Preceding gene: 150400465

Following gene: 150400467

Centisome position: 1.89

GC content: 31.76

Gene sequence:

>1014_bases
ATGAAAGATTTAAGACCTATAATATGGGATAATGAAAAAAATCAATTGATATTAATTGACCAGAGAAAACTACCAAATAG
TTTGGAATATTTTGTATGTAAAACCTATGAAGATGTTGCATTTGCAATTAAAGATATGGTTGTTAGGGGAGCTCCTGCAA
TAGGCGTATCTGCGGCTTATGGAATGGCACTTGCTGAATTAAATAACAACAATATCGCTTGCGGTAGCAAGCGAGCAACG
AAAACCAAAGGTTTTCGTCTAATAGAAAAAGCACACAATGAGTTAAAAAACACAAGACCAACAGCCGTAAATTTATTTTG
GGCTTTGGATAGATGTATGGAAGCATACAAAAACAATAAATCAATATTAAACGAAGCAAAAGAAATACATAATGAAGACA
TAGAAATATGTAAAAAAATAGGGCAAATAGGGGAAAAAATAATAAATGACGGAGATACAATTTTAACACATTGCAATGCG
GGAGCTTTGGCAACTTCGGCATATGGAACAGCTTTAAGTGTGATTAGATTTGCCCACTATAACAACAAAAAAATCAGCGT
CATAGCAGATGAAACCAGGCCCCGATTACAGGGGGCAAATCTAACGGCTTATGAGTTAAATTATGAAAATATACCTGTTA
AAGTAATAACTGATAATACCGCAGGATTTTTAATGAAAATGGGAAAAATAGATAAAATAATTGTAGGGGCAGATAGAATA
TTAAAAGATTATACGGTATTTAATAAAATTGGGACATATTCTCTTGCAGTGTTGGCAAAATATCATAATGTGCCTTTTTA
TGTGGGAGCTCCCTACTCTACATTTGATTATGAAAATAGCATTGAAGATATTATAATTGAAGAAAGAGACGAAAAAGAAG
TAAAATATATAAACAATATAAATATTATGCCAGAAGGCGTTTCTGTGTATAATTATGCTTTTGATAGCACACCTGCGGAA
TTAATTACTGGAATAATCACAGAAAAAGAAATAATTTATCCAAATAAAAAATAA

Upstream 100 bases:

>100_bases
ATTAAACAATTTATATTATGGGACCTCCAAAATGTTCTGAAATAAAATTAGTTTAGAATTTTAAGATTTACGAATTATTA
ATATATATGGATATGATATT

Downstream 100 bases:

>100_bases
TAAATATATAAATAATAAATATATAATACAAATATCAAAATATAAAATTATTATAAAATTATAAAAACTAAATAAGGAGA
TATAAAATGTATGCATTAGG

Product: aIF-2BI family translation initiation factor

Products: NA

Alternate protein names: M1Pi; MTR-1-P isomerase; MTNA-like protein; aMTNA; S-methyl-5-thioribose-1-phosphate isomerase [H]

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MKDLRPIIWDNEKNQLILIDQRKLPNSLEYFVCKTYEDVAFAIKDMVVRGAPAIGVSAAYGMALAELNNNNIACGSKRAT
KTKGFRLIEKAHNELKNTRPTAVNLFWALDRCMEAYKNNKSILNEAKEIHNEDIEICKKIGQIGEKIINDGDTILTHCNA
GALATSAYGTALSVIRFAHYNNKKISVIADETRPRLQGANLTAYELNYENIPVKVITDNTAGFLMKMGKIDKIIVGADRI
LKDYTVFNKIGTYSLAVLAKYHNVPFYVGAPYSTFDYENSIEDIIIEERDEKEVKYINNINIMPEGVSVYNYAFDSTPAE
LITGIITEKEIIYPNKK

Sequences:

>Translated_337_residues
MKDLRPIIWDNEKNQLILIDQRKLPNSLEYFVCKTYEDVAFAIKDMVVRGAPAIGVSAAYGMALAELNNNNIACGSKRAT
KTKGFRLIEKAHNELKNTRPTAVNLFWALDRCMEAYKNNKSILNEAKEIHNEDIEICKKIGQIGEKIINDGDTILTHCNA
GALATSAYGTALSVIRFAHYNNKKISVIADETRPRLQGANLTAYELNYENIPVKVITDNTAGFLMKMGKIDKIIVGADRI
LKDYTVFNKIGTYSLAVLAKYHNVPFYVGAPYSTFDYENSIEDIIIEERDEKEVKYINNINIMPEGVSVYNYAFDSTPAE
LITGIITEKEIIYPNKK
>Mature_337_residues
MKDLRPIIWDNEKNQLILIDQRKLPNSLEYFVCKTYEDVAFAIKDMVVRGAPAIGVSAAYGMALAELNNNNIACGSKRAT
KTKGFRLIEKAHNELKNTRPTAVNLFWALDRCMEAYKNNKSILNEAKEIHNEDIEICKKIGQIGEKIINDGDTILTHCNA
GALATSAYGTALSVIRFAHYNNKKISVIADETRPRLQGANLTAYELNYENIPVKVITDNTAGFLMKMGKIDKIIVGADRI
LKDYTVFNKIGTYSLAVLAKYHNVPFYVGAPYSTFDYENSIEDIIIEERDEKEVKYINNINIMPEGVSVYNYAFDSTPAE
LITGIITEKEIIYPNKK

Specific function: Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) [H]

COG id: COG0182

COG function: function code J; Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily [H]

Homologues:

Organism=Homo sapiens, GI72534748, Length=345, Percent_Identity=35.9420289855072, Blast_Score=199, Evalue=3e-51,
Organism=Homo sapiens, GI23943880, Length=328, Percent_Identity=32.6219512195122, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI4503503, Length=162, Percent_Identity=36.4197530864198, Blast_Score=84, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17557462, Length=336, Percent_Identity=35.1190476190476, Blast_Score=166, Evalue=2e-41,
Organism=Saccharomyces cerevisiae, GI6325375, Length=399, Percent_Identity=32.8320802005013, Blast_Score=159, Evalue=4e-40,
Organism=Saccharomyces cerevisiae, GI6322878, Length=236, Percent_Identity=27.1186440677966, Blast_Score=70, Evalue=6e-13,
Organism=Drosophila melanogaster, GI21357667, Length=349, Percent_Identity=37.2492836676218, Blast_Score=204, Evalue=7e-53,
Organism=Drosophila melanogaster, GI24651647, Length=349, Percent_Identity=37.2492836676218, Blast_Score=204, Evalue=7e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000649
- InterPro:   IPR005251
- InterPro:   IPR011559 [H]

Pfam domain/function: PF01008 IF-2B [H]

EC number: =5.3.1.23 [H]

Molecular weight: Translated: 37939; Mature: 37939

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDLRPIIWDNEKNQLILIDQRKLPNSLEYFVCKTYEDVAFAIKDMVVRGAPAIGVSAAY
CCCCCCCEECCCCCEEEEEECCCCCCCCCEEEECCHHHHHHHHHHHHHCCCCCCCHHHHH
GMALAELNNNNIACGSKRATKTKGFRLIEKAHNELKNTRPTAVNLFWALDRCMEAYKNNK
HEEEEEECCCCEECCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCH
SILNEAKEIHNEDIEICKKIGQIGEKIINDGDTILTHCNAGALATSAYGTALSVIRFAHY
HHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCC
NNKKISVIADETRPRLQGANLTAYELNYENIPVKVITDNTAGFLMKMGKIDKIIVGADRI
CCCEEEEEECCCCCCCCCCCEEEEEECCCCCCEEEEECCCCHHHHHHCCCCEEEECHHHH
LKDYTVFNKIGTYSLAVLAKYHNVPFYVGAPYSTFDYENSIEDIIIEERDEKEVKYINNI
HHHHHHHHHHCHHHHEEHHHHCCCCEEECCCCCCCCCCCCHHHHEECCCCCCHHHHHCCC
NIMPEGVSVYNYAFDSTPAELITGIITEKEIIYPNKK
EECCCCCEEEEEECCCCHHHHHHHHHCCCEEECCCCC
>Mature Secondary Structure
MKDLRPIIWDNEKNQLILIDQRKLPNSLEYFVCKTYEDVAFAIKDMVVRGAPAIGVSAAY
CCCCCCCEECCCCCEEEEEECCCCCCCCCEEEECCHHHHHHHHHHHHHCCCCCCCHHHHH
GMALAELNNNNIACGSKRATKTKGFRLIEKAHNELKNTRPTAVNLFWALDRCMEAYKNNK
HEEEEEECCCCEECCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCH
SILNEAKEIHNEDIEICKKIGQIGEKIINDGDTILTHCNAGALATSAYGTALSVIRFAHY
HHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCC
NNKKISVIADETRPRLQGANLTAYELNYENIPVKVITDNTAGFLMKMGKIDKIIVGADRI
CCCEEEEEECCCCCCCCCCCEEEEEECCCCCCEEEEECCCCHHHHHHCCCCEEEECHHHH
LKDYTVFNKIGTYSLAVLAKYHNVPFYVGAPYSTFDYENSIEDIIIEERDEKEVKYINNI
HHHHHHHHHHCHHHHEEHHHHCCCCEEECCCCCCCCCCCCHHHHEECCCCCCHHHHHCCC
NIMPEGVSVYNYAFDSTPAELITGIITEKEIIYPNKK
EECCCCCEEEEEECCCCHHHHHHHHHCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]