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The map label for this gene is uvrC [H]

Identifier: 150400337

GI number: 150400337

Start: 1616558

End: 1618141

Strand: Reverse

Name: uvrC [H]

Synonym: Mevan_1600

Alternate gene names: 150400337

Gene position: 1618141-1616558 (Counterclockwise)

Preceding gene: 150400338

Following gene: 150400336

Centisome position: 94.08

GC content: 27.97

Gene sequence:

>1584_bases
ATGATTAATCTATCAGTTATTCCAAAAGAACCAGGATGCTACATATATAGGGATATTGAAAAAAATATAATATATGTTGG
AAAAGCAAAAAATCTAAAAAAGCGAATCAGTAGTTATTTTAGCAAAAAAAATCACGACACAAAAACTCAAAACTTGGTAA
AATCTATTTTTGACATAGAATTTATTGTTACAAATAACGAAATTGAAGCATTGCTTTTAGAAAGCATTTTGATTAAAAAA
CACTCTCCCAAATATAATATAGATTTAAAGGACTCAAAAAATTATGCTTATATTTACATAAGCGAAGAGAATTTTCCAAG
AATTGGGATATCAAGAAATAAATCAGAAAAAGGAAAGTTTTATGGGCCATTTATTTCTGCAAAGGAAAGAGATTATGTTC
TTGATATTTTAAAAAAAACTTTTAAAATAAGGTCATGCAAAAATATGCAGAAACGACCATGTCTAAGGCACCATATAAAA
AATTGTACTGCACCGTGTACGGGAAATATTGCGTCTAAAAAATACTTGGATCAGATAAAAAAGGCAGAATATATATTAAA
AGGAAATATAGAATCTTTAATTTCAAAATTAAAAGATGAAATGATTATTAAATCAAAAAATCTCCAGTTTGAGGAAGCAA
TATTAATACGGGAAGAAATATCTGCTATTGAAAATCTGAAAACTAAGCAGAACATTAACAGGCAGAAAAATTATGATGAA
GATATTATTGCATATATTGAAAAAGATGGGAATATCCATATTATTGTATTTAACGTGTTAAAAGGAACATTATATGATAA
AAAATATTTTAAATTTGAATACGTAGAAAATTTCTTTGAAGAATTTTTAATACAATATTATTCCGAAAACCGCCCGCCTT
CTGAAATAATAATTTCAGGTTTTCCAAAAGATTTTGAAGACTTTTCAAAGGAATACAATCCAAATGCACTTTTAGAATTT
TTATCAAAAAAAAGGGAATCAAAAGTTTCATTTAAAGTACCTAAAAAGGGAGAAAAAAAAGAATTGTTAAATCTTGCAAT
GAAAAATCTTGAAATCTTGGTTTTAGGAAATGATTTAAAAGTTGAAGCCTTAAAAAACAAATTAATGCTAGAAAATCCTC
CAAAAGTTATTGAATGTTTTGATATATCCCATCTTTCCGGAAATTTTACTGTTGCATCGATGGTGCAGTTTAGGGATGGA
AAAGCGGACAAAAAAAATTACCGGAGATATAAAATTAAAACAGTTACTGGAATTGATGACTTTAAATCAATTTCTGAAGT
TGTTTTTAGGCGCTACAGTAAATTATTAAAAGAAAATTCAAAAATGCCTGATTTAATAATCATTGATGGGGGAAAGGGCC
AATTATCCTCTGCATTTTATGAATTAAAAAAGTTAAACTTAAAAATACCCGTAGTATCCATTGCAAAGAGGGAAGAAGAA
ATTTACGCTCCAGGAACTGAAAACGCCCTTCCAATAACCAAAAATGAAAAAGCGTCATTATTCATTCAGGAGATCCGTGA
TGAGGCACACCGGTTTGCAATAACATATAACAAACTTTTAAGGAAAAAGGATTTGATAAAATGA

Upstream 100 bases:

>100_bases
TTAAATTTAAAATACTTGATTTTTAATTTAAAAATTATTTGAAGTTATTTTAAAGTTATTTTAAACTTTAATTTCACTAA
AAAAAGCTTAAAGTGTTAAG

Downstream 100 bases:

>100_bases
GCTTTCCAGAATTTAGATTAAAATCAGATTTTGAGCCAAAGGGGTCTCAACCAAGTGCAATTGATAAACTTGTTTTTGAT
TTAACTAAAAATCCAGAAAA

Product: excinuclease ABC subunit C

Products: NA

Alternate protein names: Protein uvrC; Excinuclease ABC subunit C [H]

Number of amino acids: Translated: 527; Mature: 527

Protein sequence:

>527_residues
MINLSVIPKEPGCYIYRDIEKNIIYVGKAKNLKKRISSYFSKKNHDTKTQNLVKSIFDIEFIVTNNEIEALLLESILIKK
HSPKYNIDLKDSKNYAYIYISEENFPRIGISRNKSEKGKFYGPFISAKERDYVLDILKKTFKIRSCKNMQKRPCLRHHIK
NCTAPCTGNIASKKYLDQIKKAEYILKGNIESLISKLKDEMIIKSKNLQFEEAILIREEISAIENLKTKQNINRQKNYDE
DIIAYIEKDGNIHIIVFNVLKGTLYDKKYFKFEYVENFFEEFLIQYYSENRPPSEIIISGFPKDFEDFSKEYNPNALLEF
LSKKRESKVSFKVPKKGEKKELLNLAMKNLEILVLGNDLKVEALKNKLMLENPPKVIECFDISHLSGNFTVASMVQFRDG
KADKKNYRRYKIKTVTGIDDFKSISEVVFRRYSKLLKENSKMPDLIIIDGGKGQLSSAFYELKKLNLKIPVVSIAKREEE
IYAPGTENALPITKNEKASLFIQEIRDEAHRFAITYNKLLRKKDLIK

Sequences:

>Translated_527_residues
MINLSVIPKEPGCYIYRDIEKNIIYVGKAKNLKKRISSYFSKKNHDTKTQNLVKSIFDIEFIVTNNEIEALLLESILIKK
HSPKYNIDLKDSKNYAYIYISEENFPRIGISRNKSEKGKFYGPFISAKERDYVLDILKKTFKIRSCKNMQKRPCLRHHIK
NCTAPCTGNIASKKYLDQIKKAEYILKGNIESLISKLKDEMIIKSKNLQFEEAILIREEISAIENLKTKQNINRQKNYDE
DIIAYIEKDGNIHIIVFNVLKGTLYDKKYFKFEYVENFFEEFLIQYYSENRPPSEIIISGFPKDFEDFSKEYNPNALLEF
LSKKRESKVSFKVPKKGEKKELLNLAMKNLEILVLGNDLKVEALKNKLMLENPPKVIECFDISHLSGNFTVASMVQFRDG
KADKKNYRRYKIKTVTGIDDFKSISEVVFRRYSKLLKENSKMPDLIIIDGGKGQLSSAFYELKKLNLKIPVVSIAKREEE
IYAPGTENALPITKNEKASLFIQEIRDEAHRFAITYNKLLRKKDLIK
>Mature_527_residues
MINLSVIPKEPGCYIYRDIEKNIIYVGKAKNLKKRISSYFSKKNHDTKTQNLVKSIFDIEFIVTNNEIEALLLESILIKK
HSPKYNIDLKDSKNYAYIYISEENFPRIGISRNKSEKGKFYGPFISAKERDYVLDILKKTFKIRSCKNMQKRPCLRHHIK
NCTAPCTGNIASKKYLDQIKKAEYILKGNIESLISKLKDEMIIKSKNLQFEEAILIREEISAIENLKTKQNINRQKNYDE
DIIAYIEKDGNIHIIVFNVLKGTLYDKKYFKFEYVENFFEEFLIQYYSENRPPSEIIISGFPKDFEDFSKEYNPNALLEF
LSKKRESKVSFKVPKKGEKKELLNLAMKNLEILVLGNDLKVEALKNKLMLENPPKVIECFDISHLSGNFTVASMVQFRDG
KADKKNYRRYKIKTVTGIDDFKSISEVVFRRYSKLLKENSKMPDLIIIDGGKGQLSSAFYELKKLNLKIPVVSIAKREEE
IYAPGTENALPITKNEKASLFIQEIRDEAHRFAITYNKLLRKKDLIK

Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision [H]

COG id: COG0322

COG function: function code L; Nuclease subunit of the excinuclease complex

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Escherichia coli, GI87081999, Length=554, Percent_Identity=34.2960288808664, Blast_Score=276, Evalue=2e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001943
- InterPro:   IPR009055
- InterPro:   IPR004791
- InterPro:   IPR001162
- InterPro:   IPR000305 [H]

Pfam domain/function: PF01541 GIY-YIG; PF02151 UVR; PF08459 UvrC_HhH_N [H]

EC number: NA

Molecular weight: Translated: 61465; Mature: 61465

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: PS50151 UVR ; PS50164 UVRC_1 ; PS50165 UVRC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINLSVIPKEPGCYIYRDIEKNIIYVGKAKNLKKRISSYFSKKNHDTKTQNLVKSIFDIE
CEEEEEECCCCCEEEEEECCCCEEEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCEE
FIVTNNEIEALLLESILIKKHSPKYNIDLKDSKNYAYIYISEENFPRIGISRNKSEKGKF
EEEECCCHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEEECCCCCCCCCCCCCCCCCCE
YGPFISAKERDYVLDILKKTFKIRSCKNMQKRPCLRHHIKNCTAPCTGNIASKKYLDQIK
ECCCCCCCCHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHCCCCCCCCCCHHHHHHHHHH
KAEYILKGNIESLISKLKDEMIIKSKNLQFEEAILIREEISAIENLKTKQNINRQKNYDE
HHHHHCCCCHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
DIIAYIEKDGNIHIIVFNVLKGTLYDKKYFKFEYVENFFEEFLIQYYSENRPPSEIIISG
CEEEEEECCCCEEEEEEEEHHCHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHEEEEC
FPKDFEDFSKEYNPNALLEFLSKKRESKVSFKVPKKGEKKELLNLAMKNLEILVLGNDLK
CCCCHHHHHHCCCHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHCEEEEEECCCCC
VEALKNKLMLENPPKVIECFDISHLSGNFTVASMVQFRDGKADKKNYRRYKIKTVTGIDD
HHHHHCCCCCCCCCCEEEEEEEEECCCCCCHHHHHHHCCCCCCCCCCCEEEEEEECCCHH
FKSISEVVFRRYSKLLKENSKMPDLIIIDGGKGQLSSAFYELKKLNLKIPVVSIAKREEE
HHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHCCEEECEEHHHHCCCC
IYAPGTENALPITKNEKASLFIQEIRDEAHRFAITYNKLLRKKDLIK
EECCCCCCCCCCCCCCHHHHHHHHHHHHHHHEEHHHHHHHHHHHCCC
>Mature Secondary Structure
MINLSVIPKEPGCYIYRDIEKNIIYVGKAKNLKKRISSYFSKKNHDTKTQNLVKSIFDIE
CEEEEEECCCCCEEEEEECCCCEEEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCEE
FIVTNNEIEALLLESILIKKHSPKYNIDLKDSKNYAYIYISEENFPRIGISRNKSEKGKF
EEEECCCHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEEECCCCCCCCCCCCCCCCCCE
YGPFISAKERDYVLDILKKTFKIRSCKNMQKRPCLRHHIKNCTAPCTGNIASKKYLDQIK
ECCCCCCCCHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHCCCCCCCCCCHHHHHHHHHH
KAEYILKGNIESLISKLKDEMIIKSKNLQFEEAILIREEISAIENLKTKQNINRQKNYDE
HHHHHCCCCHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
DIIAYIEKDGNIHIIVFNVLKGTLYDKKYFKFEYVENFFEEFLIQYYSENRPPSEIIISG
CEEEEEECCCCEEEEEEEEHHCHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHEEEEC
FPKDFEDFSKEYNPNALLEFLSKKRESKVSFKVPKKGEKKELLNLAMKNLEILVLGNDLK
CCCCHHHHHHCCCHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHCEEEEEECCCCC
VEALKNKLMLENPPKVIECFDISHLSGNFTVASMVQFRDGKADKKNYRRYKIKTVTGIDD
HHHHHCCCCCCCCCCEEEEEEEEECCCCCCHHHHHHHCCCCCCCCCCCEEEEEEECCCHH
FKSISEVVFRRYSKLLKENSKMPDLIIIDGGKGQLSSAFYELKKLNLKIPVVSIAKREEE
HHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHCCEEECEEHHHHCCCC
IYAPGTENALPITKNEKASLFIQEIRDEAHRFAITYNKLLRKKDLIK
EECCCCCCCCCCCCCCHHHHHHHHHHHHHHHEEHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA