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The map label for this gene is uvrB [H]

Identifier: 150400336

GI number: 150400336

Start: 1614612

End: 1616561

Strand: Reverse

Name: uvrB [H]

Synonym: Mevan_1599

Alternate gene names: 150400336

Gene position: 1616561-1614612 (Counterclockwise)

Preceding gene: 150400337

Following gene: 150400329

Centisome position: 93.98

GC content: 32.21

Gene sequence:

>1950_bases
ATGAGCTTTCCAGAATTTAGATTAAAATCAGATTTTGAGCCAAAGGGGTCTCAACCAAGTGCAATTGATAAACTTGTTTT
TGATTTAACTAAAAATCCAGAAAATAGTAAGCAAACTCTTCTTGGAGTGACAGGTTCTGGAAAAACATTTACAATTGCAA
ATGTTATTGAAAAAGTTAAAAAACCAACTCTTGTAATTGCACATAATAAAACACTTGCAGCACAGCTCTACAATGAGTTT
AAGGAATTCTTTCCTGAAAACCGTGTAGAATACTTTGTATCTTACTATGACTACTATCAACCTGAATCATATATTCCACA
AAAAGATCAGTATATCGAAAAGGATGCACAAATAAACCCAAAAATTGAACAAATGAGGCTTCGTGCAAGTTCTGCTATTT
TATCAAGGCGAGATGTAATTATAGTAGCATCTGTTTCCTGTATTTATGGCCTAGGTAGTCCAAAACTCTTTAAAGAAATG
GGTTTTGAGTTAAAAAAAGGCAGTAAAATCAAACGAGCAGAAATTATTGAAAAATTAGTAGATATCCAATATGAGAGAAA
CGATACAGAACTTGTTTCTGGAAGATTTAGGGTAAAAGGGGATACAATAGATATTATTCCGGGATACCAAGATGAAACTA
TAAGACTTGAACTTTTTGGCGATGAAATTGATAGAATTTACGAGCTCGACTCAAAAAATATGACTAAAAAACATGAATTA
GCTTCTTTTTATATGTATCCTGCAAAGCATTTTGTTACAACGGAAGAAAGTAAGAAAAATGCGATAAAATCTATTTTAAA
AGAACTTGATGAATGGCTACCCCACCTTGAAATGCTAAAAGCAAACCGTTTAAAACAGAAAACATTATATGATATTGAAA
TGATTGAAGAAACGGGAAGCTGTAAGGGCATTGAAAACTATTCCCGACATTTTGAAAATAGGGGTGAAAATGAACCTGCT
TATTGCCTTTTAGATTATTTTCCAGATGACTTTTTAATCGTAATTGATGAAAGCCATCAGACAATACCTCAAATTAGAGG
GATGTATAAAGGAGACCGTTCACGAAAAAAATCTTTAATAGATTATGGGTTTAGACTCCCAAGTGCATACGATAACCGCC
CTTTAAAATTTGAAGAATTTAAAAAATATATGAACAATGTAATTTTTGTGTCTGCAACTCCGGGTGAATATGAACTTGAA
AAGTCAAATCAAATCGTTGAACAGATTATTAGGCCCACAGGATTACTTGACCCAAAAGTAGAAATTAGGCCTATTAAAGG
ACAAGTTGAAGACATTATAAATGAAACTGAAAAGATGGTAAAAAGAGGAGAAAGAGTCCTAATTACAACACTTACAAAAC
GGTTATCTGAGGAATTAACAGAATATTTGGCTCAAAAAAATGTAAAAGCAAGGTACTTACATTCTGACATTGATACAATT
GAAAGAACGGAAATTATAAGAAATTTAAGACTTGGAAAATTTGATTGCCTTGTTGGGATAAATCTATTAAGAGAAGGACT
TGACATTCCAGAAGTCGGTTTTGTAGGAATACTTGATGCAGATAAGGAGGGATTTTTAAGAAACGATAAAAGTTTGATTC
AGACAATTGGCCGTGCTGCAAGAAATGCAAATTCAAAAGTCGTTCTTTATGCAGATAAAATTACTGATTCAATTCAAAAA
GCAGTTTTTGAAACTAAAAGAAGGCGAAAAATTCAGGAAGAGTATAATATAAAGCATGATATTACTCCTAAAACAATTGT
AAAGCCAATTAGAGATAAAGTAGTCGATATAGTGGATATAAAACACATTCCAAAATCTGAAATTCCAAATGTAATTGTAG
AACTTGAATCTGAAATGTACCTTGCAGCAGAAGCACTGGAATTTGAAAGGGCAATCCAAATAAGGGATAAAATTGCAAAA
TTGAAGAAAAAGGCAGGTATTGAGCTTTAA

Upstream 100 bases:

>100_bases
AAAATGAAAAAGCGTCATTATTCATTCAGGAGATCCGTGATGAGGCACACCGGTTTGCAATAACATATAACAAACTTTTA
AGGAAAAAGGATTTGATAAA

Downstream 100 bases:

>100_bases
ATGTATTTGGTTCCAACTGTTAATTAAAACTCTTCATGAATTTTATTTAAATTTAAAAGTATTTTTACATGCCTGTTAAT
TTCAGACTCAATATTAGATA

Product: excinuclease ABC subunit B

Products: NA

Alternate protein names: Protein uvrB; Excinuclease ABC subunit B [H]

Number of amino acids: Translated: 649; Mature: 648

Protein sequence:

>649_residues
MSFPEFRLKSDFEPKGSQPSAIDKLVFDLTKNPENSKQTLLGVTGSGKTFTIANVIEKVKKPTLVIAHNKTLAAQLYNEF
KEFFPENRVEYFVSYYDYYQPESYIPQKDQYIEKDAQINPKIEQMRLRASSAILSRRDVIIVASVSCIYGLGSPKLFKEM
GFELKKGSKIKRAEIIEKLVDIQYERNDTELVSGRFRVKGDTIDIIPGYQDETIRLELFGDEIDRIYELDSKNMTKKHEL
ASFYMYPAKHFVTTEESKKNAIKSILKELDEWLPHLEMLKANRLKQKTLYDIEMIEETGSCKGIENYSRHFENRGENEPA
YCLLDYFPDDFLIVIDESHQTIPQIRGMYKGDRSRKKSLIDYGFRLPSAYDNRPLKFEEFKKYMNNVIFVSATPGEYELE
KSNQIVEQIIRPTGLLDPKVEIRPIKGQVEDIINETEKMVKRGERVLITTLTKRLSEELTEYLAQKNVKARYLHSDIDTI
ERTEIIRNLRLGKFDCLVGINLLREGLDIPEVGFVGILDADKEGFLRNDKSLIQTIGRAARNANSKVVLYADKITDSIQK
AVFETKRRRKIQEEYNIKHDITPKTIVKPIRDKVVDIVDIKHIPKSEIPNVIVELESEMYLAAEALEFERAIQIRDKIAK
LKKKAGIEL

Sequences:

>Translated_649_residues
MSFPEFRLKSDFEPKGSQPSAIDKLVFDLTKNPENSKQTLLGVTGSGKTFTIANVIEKVKKPTLVIAHNKTLAAQLYNEF
KEFFPENRVEYFVSYYDYYQPESYIPQKDQYIEKDAQINPKIEQMRLRASSAILSRRDVIIVASVSCIYGLGSPKLFKEM
GFELKKGSKIKRAEIIEKLVDIQYERNDTELVSGRFRVKGDTIDIIPGYQDETIRLELFGDEIDRIYELDSKNMTKKHEL
ASFYMYPAKHFVTTEESKKNAIKSILKELDEWLPHLEMLKANRLKQKTLYDIEMIEETGSCKGIENYSRHFENRGENEPA
YCLLDYFPDDFLIVIDESHQTIPQIRGMYKGDRSRKKSLIDYGFRLPSAYDNRPLKFEEFKKYMNNVIFVSATPGEYELE
KSNQIVEQIIRPTGLLDPKVEIRPIKGQVEDIINETEKMVKRGERVLITTLTKRLSEELTEYLAQKNVKARYLHSDIDTI
ERTEIIRNLRLGKFDCLVGINLLREGLDIPEVGFVGILDADKEGFLRNDKSLIQTIGRAARNANSKVVLYADKITDSIQK
AVFETKRRRKIQEEYNIKHDITPKTIVKPIRDKVVDIVDIKHIPKSEIPNVIVELESEMYLAAEALEFERAIQIRDKIAK
LKKKAGIEL
>Mature_648_residues
SFPEFRLKSDFEPKGSQPSAIDKLVFDLTKNPENSKQTLLGVTGSGKTFTIANVIEKVKKPTLVIAHNKTLAAQLYNEFK
EFFPENRVEYFVSYYDYYQPESYIPQKDQYIEKDAQINPKIEQMRLRASSAILSRRDVIIVASVSCIYGLGSPKLFKEMG
FELKKGSKIKRAEIIEKLVDIQYERNDTELVSGRFRVKGDTIDIIPGYQDETIRLELFGDEIDRIYELDSKNMTKKHELA
SFYMYPAKHFVTTEESKKNAIKSILKELDEWLPHLEMLKANRLKQKTLYDIEMIEETGSCKGIENYSRHFENRGENEPAY
CLLDYFPDDFLIVIDESHQTIPQIRGMYKGDRSRKKSLIDYGFRLPSAYDNRPLKFEEFKKYMNNVIFVSATPGEYELEK
SNQIVEQIIRPTGLLDPKVEIRPIKGQVEDIINETEKMVKRGERVLITTLTKRLSEELTEYLAQKNVKARYLHSDIDTIE
RTEIIRNLRLGKFDCLVGINLLREGLDIPEVGFVGILDADKEGFLRNDKSLIQTIGRAARNANSKVVLYADKITDSIQKA
VFETKRRRKIQEEYNIKHDITPKTIVKPIRDKVVDIVDIKHIPKSEIPNVIVELESEMYLAAEALEFERAIQIRDKIAKL
KKKAGIEL

Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. Upon binding of the uvrA(2)B(2) complex to a putative damaged site, the DNA

COG id: COG0556

COG function: function code L; Helicase subunit of the DNA excision repair complex

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Escherichia coli, GI1786996, Length=670, Percent_Identity=53.7313432835821, Blast_Score=683, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR006935
- InterPro:   IPR001943
- InterPro:   IPR004807
- InterPro:   IPR009055 [H]

Pfam domain/function: PF00271 Helicase_C; PF04851 ResIII; PF02151 UVR [H]

EC number: NA

Molecular weight: Translated: 75178; Mature: 75046

Theoretical pI: Translated: 7.94; Mature: 7.94

Prosite motif: PS50151 UVR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFPEFRLKSDFEPKGSQPSAIDKLVFDLTKNPENSKQTLLGVTGSGKTFTIANVIEKVK
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCEEEEEECCCCEEEHHHHHHHHC
KPTLVIAHNKTLAAQLYNEFKEFFPENRVEYFVSYYDYYQPESYIPQKDQYIEKDAQINP
CCEEEEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCC
KIEQMRLRASSAILSRRDVIIVASVSCIYGLGSPKLFKEMGFELKKGSKIKRAEIIEKLV
HHHHHHHHHHHHHHCCCCEEEEEEHHHHHCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHH
DIQYERNDTELVSGRFRVKGDTIDIIPGYQDETIRLELFGDEIDRIYELDSKNMTKKHEL
CCEECCCCCHHHCCEEEEECCEEEECCCCCCCEEEEEEECCHHHHHHHCCCCCCCHHHHH
ASFYMYPAKHFVTTEESKKNAIKSILKELDEWLPHLEMLKANRLKQKTLYDIEMIEETGS
HHHHCCCCHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
CKGIENYSRHFENRGENEPAYCLLDYFPDDFLIVIDESHQTIPQIRGMYKGDRSRKKSLI
CCCCHHHHHHHHCCCCCCCCEEEEEECCCCEEEEECCCCCHHHHHHHHHCCCHHHHHHHH
DYGFRLPSAYDNRPLKFEEFKKYMNNVIFVSATPGEYELEKSNQIVEQIIRPTGLLDPKV
HHCCCCCCCCCCCCCCHHHHHHHHCCEEEEEECCCCCEEHHHHHHHHHHHCCCCCCCCCE
EIRPIKGQVEDIINETEKMVKRGERVLITTLTKRLSEELTEYLAQKNVKARYLHSDIDTI
EEEECCCHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
ERTEIIRNLRLGKFDCLVGINLLREGLDIPEVGFVGILDADKEGFLRNDKSLIQTIGRAA
HHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHH
RNANSKVVLYADKITDSIQKAVFETKRRRKIQEEYNIKHDITPKTIVKPIRDKVVDIVDI
CCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
KHIPKSEIPNVIVELESEMYLAAEALEFERAIQIRDKIAKLKKKAGIEL
CCCCHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SFPEFRLKSDFEPKGSQPSAIDKLVFDLTKNPENSKQTLLGVTGSGKTFTIANVIEKVK
CCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCEEEEEECCCCEEEHHHHHHHHC
KPTLVIAHNKTLAAQLYNEFKEFFPENRVEYFVSYYDYYQPESYIPQKDQYIEKDAQINP
CCEEEEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCC
KIEQMRLRASSAILSRRDVIIVASVSCIYGLGSPKLFKEMGFELKKGSKIKRAEIIEKLV
HHHHHHHHHHHHHHCCCCEEEEEEHHHHHCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHH
DIQYERNDTELVSGRFRVKGDTIDIIPGYQDETIRLELFGDEIDRIYELDSKNMTKKHEL
CCEECCCCCHHHCCEEEEECCEEEECCCCCCCEEEEEEECCHHHHHHHCCCCCCCHHHHH
ASFYMYPAKHFVTTEESKKNAIKSILKELDEWLPHLEMLKANRLKQKTLYDIEMIEETGS
HHHHCCCCHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
CKGIENYSRHFENRGENEPAYCLLDYFPDDFLIVIDESHQTIPQIRGMYKGDRSRKKSLI
CCCCHHHHHHHHCCCCCCCCEEEEEECCCCEEEEECCCCCHHHHHHHHHCCCHHHHHHHH
DYGFRLPSAYDNRPLKFEEFKKYMNNVIFVSATPGEYELEKSNQIVEQIIRPTGLLDPKV
HHCCCCCCCCCCCCCCHHHHHHHHCCEEEEEECCCCCEEHHHHHHHHHHHCCCCCCCCCE
EIRPIKGQVEDIINETEKMVKRGERVLITTLTKRLSEELTEYLAQKNVKARYLHSDIDTI
EEEECCCHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
ERTEIIRNLRLGKFDCLVGINLLREGLDIPEVGFVGILDADKEGFLRNDKSLIQTIGRAA
HHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHH
RNANSKVVLYADKITDSIQKAVFETKRRRKIQEEYNIKHDITPKTIVKPIRDKVVDIVDI
CCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
KHIPKSEIPNVIVELESEMYLAAEALEFERAIQIRDKIAKLKKKAGIEL
CCCCHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: Hydrolase; Acting on ester bonds [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA