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The map label for this gene is ilvH [H]

Identifier: 150400279

GI number: 150400279

Start: 1555731

End: 1556240

Strand: Reverse

Name: ilvH [H]

Synonym: Mevan_1542

Alternate gene names: 150400279

Gene position: 1556240-1555731 (Counterclockwise)

Preceding gene: 150400280

Following gene: 150400276

Centisome position: 90.48

GC content: 32.94

Gene sequence:

>510_bases
ATGGAACACAAACATATTATTTCGGTCTTAGTACTACATAGGCCAGGAGTACTCCAAAGAATTTCAGGATTATTTACAAG
AAGATGGTTTAATATATCAAGCATTACTGTTGGAAGCACTGAAAATCCAGAAATTGCAAGAATGACTATCGTAGTAAATG
GAGACGATAATGTACTTGAACAGGTAATAAAACAGTTGAATAAACTTGTTGAAGTTGTAAAAGTAACTGATTTAAACAGT
AGTAAATCTGTTCAAAGAGAACTCTGCCTTGTAAAAGTTTATGCGCCAACCGAAGACAGTAAATCCCAAGTAATCCAGTA
TGTAAATATATTTCGTGGAAAAATTATTGATTTAAGTACTGAAACACTTACTGTTGAAATCACAGGGGATGAACAAAAAG
TAAACGCATTTTTAGACCTTGTAAGGCCAATGGGCATAAAAGAAATTGCAAGAACAGGTTTAACGGCACTTATGAGGGGT
TCTAAAATATTAAAATCAAATAAGGCATAA

Upstream 100 bases:

>100_bases
ACATATTATTCCCTGAAAGACAGGAACCTACTCCAAAGCCCACTTGCTTTAATGACATGAAAAAAATTCTTAATTTAAAG
GTCTAATCAGGTGATTTCCA

Downstream 100 bases:

>100_bases
CTCATTATTTAATATTTAAATATTACTACATTACAGTATATGGCTTAAAGTAACTTAAAACGTAGTAAACAGTAGTAAAT
CTGTTCAAAGAGAACTCTGC

Product: acetolactate synthase 3 regulatory subunit

Products: NA

Alternate protein names: Acetohydroxy-acid synthase small subunit; AHAS; ALS [H]

Number of amino acids: Translated: 169; Mature: 169

Protein sequence:

>169_residues
MEHKHIISVLVLHRPGVLQRISGLFTRRWFNISSITVGSTENPEIARMTIVVNGDDNVLEQVIKQLNKLVEVVKVTDLNS
SKSVQRELCLVKVYAPTEDSKSQVIQYVNIFRGKIIDLSTETLTVEITGDEQKVNAFLDLVRPMGIKEIARTGLTALMRG
SKILKSNKA

Sequences:

>Translated_169_residues
MEHKHIISVLVLHRPGVLQRISGLFTRRWFNISSITVGSTENPEIARMTIVVNGDDNVLEQVIKQLNKLVEVVKVTDLNS
SKSVQRELCLVKVYAPTEDSKSQVIQYVNIFRGKIIDLSTETLTVEITGDEQKVNAFLDLVRPMGIKEIARTGLTALMRG
SKILKSNKA
>Mature_169_residues
MEHKHIISVLVLHRPGVLQRISGLFTRRWFNISSITVGSTENPEIARMTIVVNGDDNVLEQVIKQLNKLVEVVKVTDLNS
SKSVQRELCLVKVYAPTEDSKSQVIQYVNIFRGKIIDLSTETLTVEITGDEQKVNAFLDLVRPMGIKEIARTGLTALMRG
SKILKSNKA

Specific function: Valine and isoleucine biosynthesis; first step. [C]

COG id: COG0440

COG function: function code E; Acetolactate synthase, small (regulatory) subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ACT domain [H]

Homologues:

Organism=Escherichia coli, GI1786266, Length=163, Percent_Identity=42.9447852760736, Blast_Score=134, Evalue=4e-33,
Organism=Saccharomyces cerevisiae, GI6319837, Length=204, Percent_Identity=30.3921568627451, Blast_Score=105, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004789
- InterPro:   IPR019455
- InterPro:   IPR002912 [H]

Pfam domain/function: PF01842 ACT; PF10369 ALS_ss_C [H]

EC number: =2.2.1.6 [H]

Molecular weight: Translated: 18927; Mature: 18927

Theoretical pI: Translated: 10.07; Mature: 10.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEHKHIISVLVLHRPGVLQRISGLFTRRWFNISSITVGSTENPEIARMTIVVNGDDNVLE
CCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCEEEEEEEEECCHHHHH
QVIKQLNKLVEVVKVTDLNSSKSVQRELCLVKVYAPTEDSKSQVIQYVNIFRGKIIDLST
HHHHHHHHHHHHHHHCCCCCCHHHHHHEEEEEEECCCCCCHHHHHHHHHHHCCEEEEECC
ETLTVEITGDEQKVNAFLDLVRPMGIKEIARTGLTALMRGSKILKSNKA
CEEEEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHCCCCC
>Mature Secondary Structure
MEHKHIISVLVLHRPGVLQRISGLFTRRWFNISSITVGSTENPEIARMTIVVNGDDNVLE
CCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCEEEEEEEEECCHHHHH
QVIKQLNKLVEVVKVTDLNSSKSVQRELCLVKVYAPTEDSKSQVIQYVNIFRGKIIDLST
HHHHHHHHHHHHHHHCCCCCCHHHHHHEEEEEEECCCCCCHHHHHHHHHHHCCEEEEECC
ETLTVEITGDEQKVNAFLDLVRPMGIKEIARTGLTALMRGSKILKSNKA
CEEEEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]