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The map label for this gene is pyrF [H]

Identifier: 150400213

GI number: 150400213

Start: 1497834

End: 1498469

Strand: Reverse

Name: pyrF [H]

Synonym: Mevan_1474

Alternate gene names: 150400213

Gene position: 1498469-1497834 (Counterclockwise)

Preceding gene: 150400217

Following gene: 150400212

Centisome position: 87.12

GC content: 30.03

Gene sequence:

>636_bases
ATGCTCGCACTCGATGTATTAGATGAAAAAAACGCATTAAAAATTGCAGAAGAAACTTGTGAATATATCGATTCAATAAA
AATAGGGTATCCATTAGTTTTAGGTACTGATTTAAAAATTATTGAAAAAATAAAAAATCTTACAGGTAAAGAAGTAATCT
GCGATTTTAAAGTTGCGGATATTCCTTCAACAAATGAAAAAATAGCAGAATTGACTCTAAATTACGCTGACGGGATAATA
TGTCAGGGTTTTGTTGGTAAAGATAGCGTTTCTGCAATTTTAAACATTGCAAGGAAAAAAAATAAAAAAGTAATAGTTGT
AACTGAAATGTCGCATCCGGGAGCTACTGAATATTTAAAAAACGTAGCAAATGATATGGCAGATATGGCAAAGAATTTAA
AGGTTGATGGAATTGTTGCACCTTCAACAAGAGTAGAAAGGTTAAAAGAGCTTAAAAAAATTGTTGGAGATTTATTTATA
ATTTCTCCGGGCGTTGGTGCACAGGGTGGAGATTTAAAAGAAGTTTTAAATGTTTTAGATGAAAATGACTATGTTATTAT
TGGACGAGCAATATATGAAAGTGAAAATCCAAAAGAAAGTGCTAAAAATTATAAAATGCAAATATCAACATTTTAG

Upstream 100 bases:

>100_bases
CGTAAAACGAAAATTCGTTTTTGAATTTAAATCTTTTTATAGTAATGACGTATTAATCATTTATATACTTAATTATGGCG
GTGGTAATTTGATAAAGTTA

Downstream 100 bases:

>100_bases
CTTTTTTTTAATAAATTGCCACATAACATTTTTATATTTTTGAAAACATATATTTAGTATAGAATAGTAATTTAATAAGG
GTGTTGAAATTTTAAAAATG

Product: orotidine 5'-phosphate decarboxylase

Products: NA

Alternate protein names: OMP decarboxylase; OMPDCase; OMPdecase [H]

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MLALDVLDEKNALKIAEETCEYIDSIKIGYPLVLGTDLKIIEKIKNLTGKEVICDFKVADIPSTNEKIAELTLNYADGII
CQGFVGKDSVSAILNIARKKNKKVIVVTEMSHPGATEYLKNVANDMADMAKNLKVDGIVAPSTRVERLKELKKIVGDLFI
ISPGVGAQGGDLKEVLNVLDENDYVIIGRAIYESENPKESAKNYKMQISTF

Sequences:

>Translated_211_residues
MLALDVLDEKNALKIAEETCEYIDSIKIGYPLVLGTDLKIIEKIKNLTGKEVICDFKVADIPSTNEKIAELTLNYADGII
CQGFVGKDSVSAILNIARKKNKKVIVVTEMSHPGATEYLKNVANDMADMAKNLKVDGIVAPSTRVERLKELKKIVGDLFI
ISPGVGAQGGDLKEVLNVLDENDYVIIGRAIYESENPKESAKNYKMQISTF
>Mature_211_residues
MLALDVLDEKNALKIAEETCEYIDSIKIGYPLVLGTDLKIIEKIKNLTGKEVICDFKVADIPSTNEKIAELTLNYADGII
CQGFVGKDSVSAILNIARKKNKKVIVVTEMSHPGATEYLKNVANDMADMAKNLKVDGIVAPSTRVERLKELKKIVGDLFI
ISPGVGAQGGDLKEVLNVLDENDYVIIGRAIYESENPKESAKNYKMQISTF

Specific function: Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) [H]

COG id: COG0284

COG function: function code F; Orotidine-5'-phosphate decarboxylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OMP decarboxylase family. Type 1 subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR014732
- InterPro:   IPR018089
- InterPro:   IPR001754
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00215 OMPdecase [H]

EC number: =4.1.1.23 [H]

Molecular weight: Translated: 23178; Mature: 23178

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS00156 OMPDECASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLALDVLDEKNALKIAEETCEYIDSIKIGYPLVLGTDLKIIEKIKNLTGKEVICDFKVAD
CEEEEECCCCCHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHHCCCCCEEEEEEEECC
IPSTNEKIAELTLNYADGIICQGFVGKDSVSAILNIARKKNKKVIVVTEMSHPGATEYLK
CCCCCHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHH
NVANDMADMAKNLKVDGIVAPSTRVERLKELKKIVGDLFIISPGVGAQGGDLKEVLNVLD
HHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHCEEEECCCCCCCCCCHHHHHHHHC
ENDYVIIGRAIYESENPKESAKNYKMQISTF
CCCEEEEEEHHHCCCCCHHHHCCEEEEEECC
>Mature Secondary Structure
MLALDVLDEKNALKIAEETCEYIDSIKIGYPLVLGTDLKIIEKIKNLTGKEVICDFKVAD
CEEEEECCCCCHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHHCCCCCEEEEEEEECC
IPSTNEKIAELTLNYADGIICQGFVGKDSVSAILNIARKKNKKVIVVTEMSHPGATEYLK
CCCCCHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHH
NVANDMADMAKNLKVDGIVAPSTRVERLKELKKIVGDLFIISPGVGAQGGDLKEVLNVLD
HHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHCEEEECCCCCCCCCCHHHHHHHHC
ENDYVIIGRAIYESENPKESAKNYKMQISTF
CCCEEEEEEHHHCCCCCHHHHCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA