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The map label for this gene is cbiL [H]

Identifier: 150400072

GI number: 150400072

Start: 1356492

End: 1357178

Strand: Reverse

Name: cbiL [H]

Synonym: Mevan_1330

Alternate gene names: 150400072

Gene position: 1357178-1356492 (Counterclockwise)

Preceding gene: 150400073

Following gene: 150400071

Centisome position: 78.9

GC content: 29.84

Gene sequence:

>687_bases
ATGGTTGATAAAATATATGGAATAGGCGTTGGGCCAGGAGATACGGATTTATTAACATTAAAATCTGTAAAAATACTAAA
TAGTGTAGAAACAATATTTGTACCAATTTCAAAGGAAGGAAAGGCTTCCGTTGCATACGAAATTATAAAAGGAATTATTC
CTGAAGATAAAAAAGTAGTTGAATTATTGTTTCCAATGAGTAAGGACATTGAATTTTTACAAAAACACTGGGAAAACGCT
GCAAAGGAGATAATTAACGAAAAAGGAACTGTTGCAGTCGTAACAATTGGGGATGCAACACTTTACAGTACATTTTCGTA
TGTATGGCAGATATTTAACAAAAATAATATTGAAGTTGAAGTCATAAATGGAATTTCTTCACCTTTTGCAGCAGCTGCTT
CCTTAAACATTCCCCTAGTTGAAGGAGATGAAAAATTAGCAATATTGCCTCAAGGAAAAGATTTAGAACGGTATTTAGAT
GAATTTGACACTTTAATCGTCATGAAAACAAATGATTTAGAAGAAAAATTGAAAAACTTAAAAAATAAAAAGGATAGTTT
TTTAGTCGGCGTTGTAAATCGAGTTACAAGTAGTAGTCAAAAAATATCGCTTGGAAAAATCGATGAAATTGATTTTGAAC
CGTTTAAAGATTATTTATCATTAGCAATTATTAAAAAATTGAAATAA

Upstream 100 bases:

>100_bases
TTATTTCAAAACCTGATAATTTTGGTTCAAAAATAATTTACTAGAGTAATTTAGTAATTTAATTTTAAAATTTTTAAAAA
TTTAAAAAAAGGTGAACGTT

Downstream 100 bases:

>100_bases
ATTTAATTTTTCATTAAATCTTTTTGAAGAACTTATAAAAAATTAAATTTATACGATACTTTTTTATCCAATCTAATTAA
ATACCAATTGGACTGTTAAT

Product: precorrin-2 C20-methyltransferase

Products: NA

Alternate protein names: S-adenosyl-L-methionine--cobalt-precorrin-2 methyltransferase [H]

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MVDKIYGIGVGPGDTDLLTLKSVKILNSVETIFVPISKEGKASVAYEIIKGIIPEDKKVVELLFPMSKDIEFLQKHWENA
AKEIINEKGTVAVVTIGDATLYSTFSYVWQIFNKNNIEVEVINGISSPFAAAASLNIPLVEGDEKLAILPQGKDLERYLD
EFDTLIVMKTNDLEEKLKNLKNKKDSFLVGVVNRVTSSSQKISLGKIDEIDFEPFKDYLSLAIIKKLK

Sequences:

>Translated_228_residues
MVDKIYGIGVGPGDTDLLTLKSVKILNSVETIFVPISKEGKASVAYEIIKGIIPEDKKVVELLFPMSKDIEFLQKHWENA
AKEIINEKGTVAVVTIGDATLYSTFSYVWQIFNKNNIEVEVINGISSPFAAAASLNIPLVEGDEKLAILPQGKDLERYLD
EFDTLIVMKTNDLEEKLKNLKNKKDSFLVGVVNRVTSSSQKISLGKIDEIDFEPFKDYLSLAIIKKLK
>Mature_228_residues
MVDKIYGIGVGPGDTDLLTLKSVKILNSVETIFVPISKEGKASVAYEIIKGIIPEDKKVVELLFPMSKDIEFLQKHWENA
AKEIINEKGTVAVVTIGDATLYSTFSYVWQIFNKNNIEVEVINGISSPFAAAASLNIPLVEGDEKLAILPQGKDLERYLD
EFDTLIVMKTNDLEEKLKNLKNKKDSFLVGVVNRVTSSSQKISLGKIDEIDFEPFKDYLSLAIIKKLK

Specific function: Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway [H]

COG id: COG2243

COG function: function code H; Precorrin-2 methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012382
- InterPro:   IPR006364
- InterPro:   IPR003043 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.151 [H]

Molecular weight: Translated: 25397; Mature: 25397

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDKIYGIGVGPGDTDLLTLKSVKILNSVETIFVPISKEGKASVAYEIIKGIIPEDKKVV
CCCCEEEECCCCCCCCEEEHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHCCCCCCHHHH
ELLFPMSKDIEFLQKHWENAAKEIINEKGTVAVVTIGDATLYSTFSYVWQIFNKNNIEVE
HHHCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHCCCCCEEE
VINGISSPFAAAASLNIPLVEGDEKLAILPQGKDLERYLDEFDTLIVMKTNDLEEKLKNL
EECCCCCCHHHHHCCCCEEEECCCEEEEECCCCCHHHHHHHHCEEEEEECCCHHHHHHHH
KNKKDSFLVGVVNRVTSSSQKISLGKIDEIDFEPFKDYLSLAIIKKLK
CCCCCHHHHHHHHHHCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVDKIYGIGVGPGDTDLLTLKSVKILNSVETIFVPISKEGKASVAYEIIKGIIPEDKKVV
CCCCEEEECCCCCCCCEEEHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHCCCCCCHHHH
ELLFPMSKDIEFLQKHWENAAKEIINEKGTVAVVTIGDATLYSTFSYVWQIFNKNNIEVE
HHHCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHCCCCCEEE
VINGISSPFAAAASLNIPLVEGDEKLAILPQGKDLERYLDEFDTLIVMKTNDLEEKLKNL
EECCCCCCHHHHHCCCCEEEECCCEEEEECCCCCHHHHHHHHCEEEEEECCCHHHHHHHH
KNKKDSFLVGVVNRVTSSSQKISLGKIDEIDFEPFKDYLSLAIIKKLK
CCCCCHHHHHHHHHHCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]