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The map label for this gene is nrdD [C]

Identifier: 150399983

GI number: 150399983

Start: 1272422

End: 1274728

Strand: Reverse

Name: nrdD [C]

Synonym: Mevan_1241

Alternate gene names: 150399983

Gene position: 1274728-1272422 (Counterclockwise)

Preceding gene: 150399985

Following gene: 150399982

Centisome position: 74.11

GC content: 33.98

Gene sequence:

>2307_bases
TTGGCATCTGGCTCAAAATATGCGGATTTAGAAATAAGTGTTGTAAAAAGAAGCGGTAATGAAGAATCCTTCAATGTAAA
TAAGTTCGTAAAATCGCTCATAACATCCGGTGTTGATTACGAAAACGTTGATACAATATTATCAGAAATTCAAGGGAAAT
TTTACAATGGAATGTCGACTGAAGACTTAAAGTCTGTGGTATATAGTATTCTAAAAGAATATGATAAAAAAACCGGAAAA
AGTTACTCTAAAAAGTACATGTCTGAAAACTGTCTAAAAATAAGAACTTCCGAAAAAGAATTTGAATCGTTTAATAAAGA
AAAAATCGTAAAAGCGTTAATTCAGGAAGCAGGAGCAGATTTAAAAACCGCTGAACGAATTGCATTAGAAGTAGAATCGG
AAGTTAAAACTTTAAATTTAAGTTATCTTACTGCCCCAATGATTAGAGAAATTGTAAATACTAAACTTATAGAACATGGA
TTAGAAGAATTCCGACATAAACACACGAGACTTGGAATTCCGGTTTATGACATTATTAAATTAATTGAAAAAGGTTCTAA
AGACAATGCAAACCTTATGCACAACCCGGAAAGTATTCATAAATGGGTTGCCGATGAAACAATGAAACAGTTTGCACTTT
TAAATGTATTCCCAAAATACATTGCAGATGCCCATATGCGAGGAGACATTCACCTTCACGACCTTGAATATGCTGCTGTA
AGAACAGTTTGTTGTCAGCATGATTTAAGGCAATTTTTCATGCACGGTTTAAAGGTAGATGGAACCGGTAGACATACAAG
TGTTTCAAAACCTGCAAAACATCCAGATGTGGCGTTACAGCATGCTGCAAAAGTATTAAGTGCTGCACAGTGTGAAATGT
CAGGTGGACAATCAATTGATGAATTTAATGTATGGATTGCACCATATATTAAAGGACTTCCTTATGATGAAGTAAAACAG
CTTATGCAATTGTTTATTTATGAAATGAACCAGATATATGCTGCAAGAGGTGGCCAAGTCGTATTTAGTTCAATAAATCT
TGAATTAGAAGTTCCAGAATATTTAAAAGGTAAACCTGCTGTAAAAGCAGGTCAAATAGTTGGAGCATACGAAGAATACG
ATTATGAAGTCAAATTAATTGCTAAAGCACTTGTTGATGTATTAATGCAAGGTGATGCGTATGGTAAACCATTCTTATTT
CCAAACATTATTTTTAAATTAAGAGAAAATGCATTTAAAGATGAAAATAAAGATTTAATGATAAAAATACACGAATTAAG
TGCTAAATGGGGACTTCCGTACTTTATAAATATGTTTGCAGATTATCAGTTCAAAAACACTAATGCAATGGGATGTAGAA
CCCGGTTGAGTGGAGATTGGGGGAATAGCGTTGAAGAAAGTTCCCTTAGAACCGGAAACATGCAGTGGTATACTGTAAAT
CTTCCAAGAATTGCTTATGAAGCAGACGGGGACGATGGAAAACTTTTTGAACTTCTTGAAGAAAAATTGAGCCTTATAAA
ACACGGTCTTGAACTAAAACACGAAATTACGAAAAAAAGGCTATATCATGATAAGACACATCCATTTTTAACTCAAAAAT
TCGATGATGAGCAGTACTATGGATACGACAACACGACAAAAACTTTCGGATTTGTAGGATTAAACGAACTTTTAAAATAC
CACGTTGGAAGCGAAATTCATGATACAAAGGATTCATTAGATTTTGGGGAAAAAGTAATTTCATTTATTCGAAATTATGC
AGATTCACTTAAAAAAGAAACTGGGCTTAGGTGGACCGTAACTCAAACGCCTGCAGAAAGTACGGCGGGAAGATTTGCAA
AGTTAGATTATAAATACTACCGGGAAGAGACTAAATCCGTTGTAAATGGGGAATTAAGCGATTTAAATAGCATCTACTAC
ACCAATTCGTCACACGTTAGGGTAAATGCACCCGTTACACTTGGGGAAAAAGTAAGTATTGAAGAAAAATTCCATTCATT
ATGTAATGGTGGGCATATCGGCCACTTCTGGAATGCTGAAGCGTATGCAAATCCAGAAGTATTGATGGAAATTACTCAAA
AAATGGCTAAAACAAACATTGGTTTTTTCACGTACACTAAAAATTTGAGTATTTGTGAAAAATGCAGTCTTGCAATGGGT
GGCTTGAAAGATAACTGTAATGGGTGCGGAAGTAATTCGATTGAAAGGTTTTCAAGAATTACGGGATATTTACAAAATGT
TTCAAACTGGAACAAAGCAAAACAGAAAGAACTAACCGATAGAAAAAGTAATTTAATTAAATTTTAG

Upstream 100 bases:

>100_bases
AGTATATTAAAAATTGCAACTTATGATTATTCAAGCCTTAAAAATCAAAACTTTTTGTTCATACCATTTTTATTTTTTTA
TACTCTTTTAGGTGATTTTG

Downstream 100 bases:

>100_bases
CTTTTTTAATTTTAAATTTTTTTAAAGTAATTTTTATATGACATATAATTTCTATAATTTTAAATACTCTTAAATATATA
AAGTGAATGATTTAACATAA

Product: anaerobic ribonucleoside-triphosphate reductase

Products: ribonucleoside triphosphate; thioredoxin

Alternate protein names: NA

Number of amino acids: Translated: 768; Mature: 767

Protein sequence:

>768_residues
MASGSKYADLEISVVKRSGNEESFNVNKFVKSLITSGVDYENVDTILSEIQGKFYNGMSTEDLKSVVYSILKEYDKKTGK
SYSKKYMSENCLKIRTSEKEFESFNKEKIVKALIQEAGADLKTAERIALEVESEVKTLNLSYLTAPMIREIVNTKLIEHG
LEEFRHKHTRLGIPVYDIIKLIEKGSKDNANLMHNPESIHKWVADETMKQFALLNVFPKYIADAHMRGDIHLHDLEYAAV
RTVCCQHDLRQFFMHGLKVDGTGRHTSVSKPAKHPDVALQHAAKVLSAAQCEMSGGQSIDEFNVWIAPYIKGLPYDEVKQ
LMQLFIYEMNQIYAARGGQVVFSSINLELEVPEYLKGKPAVKAGQIVGAYEEYDYEVKLIAKALVDVLMQGDAYGKPFLF
PNIIFKLRENAFKDENKDLMIKIHELSAKWGLPYFINMFADYQFKNTNAMGCRTRLSGDWGNSVEESSLRTGNMQWYTVN
LPRIAYEADGDDGKLFELLEEKLSLIKHGLELKHEITKKRLYHDKTHPFLTQKFDDEQYYGYDNTTKTFGFVGLNELLKY
HVGSEIHDTKDSLDFGEKVISFIRNYADSLKKETGLRWTVTQTPAESTAGRFAKLDYKYYREETKSVVNGELSDLNSIYY
TNSSHVRVNAPVTLGEKVSIEEKFHSLCNGGHIGHFWNAEAYANPEVLMEITQKMAKTNIGFFTYTKNLSICEKCSLAMG
GLKDNCNGCGSNSIERFSRITGYLQNVSNWNKAKQKELTDRKSNLIKF

Sequences:

>Translated_768_residues
MASGSKYADLEISVVKRSGNEESFNVNKFVKSLITSGVDYENVDTILSEIQGKFYNGMSTEDLKSVVYSILKEYDKKTGK
SYSKKYMSENCLKIRTSEKEFESFNKEKIVKALIQEAGADLKTAERIALEVESEVKTLNLSYLTAPMIREIVNTKLIEHG
LEEFRHKHTRLGIPVYDIIKLIEKGSKDNANLMHNPESIHKWVADETMKQFALLNVFPKYIADAHMRGDIHLHDLEYAAV
RTVCCQHDLRQFFMHGLKVDGTGRHTSVSKPAKHPDVALQHAAKVLSAAQCEMSGGQSIDEFNVWIAPYIKGLPYDEVKQ
LMQLFIYEMNQIYAARGGQVVFSSINLELEVPEYLKGKPAVKAGQIVGAYEEYDYEVKLIAKALVDVLMQGDAYGKPFLF
PNIIFKLRENAFKDENKDLMIKIHELSAKWGLPYFINMFADYQFKNTNAMGCRTRLSGDWGNSVEESSLRTGNMQWYTVN
LPRIAYEADGDDGKLFELLEEKLSLIKHGLELKHEITKKRLYHDKTHPFLTQKFDDEQYYGYDNTTKTFGFVGLNELLKY
HVGSEIHDTKDSLDFGEKVISFIRNYADSLKKETGLRWTVTQTPAESTAGRFAKLDYKYYREETKSVVNGELSDLNSIYY
TNSSHVRVNAPVTLGEKVSIEEKFHSLCNGGHIGHFWNAEAYANPEVLMEITQKMAKTNIGFFTYTKNLSICEKCSLAMG
GLKDNCNGCGSNSIERFSRITGYLQNVSNWNKAKQKELTDRKSNLIKF
>Mature_767_residues
ASGSKYADLEISVVKRSGNEESFNVNKFVKSLITSGVDYENVDTILSEIQGKFYNGMSTEDLKSVVYSILKEYDKKTGKS
YSKKYMSENCLKIRTSEKEFESFNKEKIVKALIQEAGADLKTAERIALEVESEVKTLNLSYLTAPMIREIVNTKLIEHGL
EEFRHKHTRLGIPVYDIIKLIEKGSKDNANLMHNPESIHKWVADETMKQFALLNVFPKYIADAHMRGDIHLHDLEYAAVR
TVCCQHDLRQFFMHGLKVDGTGRHTSVSKPAKHPDVALQHAAKVLSAAQCEMSGGQSIDEFNVWIAPYIKGLPYDEVKQL
MQLFIYEMNQIYAARGGQVVFSSINLELEVPEYLKGKPAVKAGQIVGAYEEYDYEVKLIAKALVDVLMQGDAYGKPFLFP
NIIFKLRENAFKDENKDLMIKIHELSAKWGLPYFINMFADYQFKNTNAMGCRTRLSGDWGNSVEESSLRTGNMQWYTVNL
PRIAYEADGDDGKLFELLEEKLSLIKHGLELKHEITKKRLYHDKTHPFLTQKFDDEQYYGYDNTTKTFGFVGLNELLKYH
VGSEIHDTKDSLDFGEKVISFIRNYADSLKKETGLRWTVTQTPAESTAGRFAKLDYKYYREETKSVVNGELSDLNSIYYT
NSSHVRVNAPVTLGEKVSIEEKFHSLCNGGHIGHFWNAEAYANPEVLMEITQKMAKTNIGFFTYTKNLSICEKCSLAMGG
LKDNCNGCGSNSIERFSRITGYLQNVSNWNKAKQKELTDRKSNLIKF

Specific function: Unknown

COG id: COG1328

COG function: function code F; Oxygen-sensitive ribonucleoside-triphosphate reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 DOD-type homing endonuclease domains [H]

Homologues:

Organism=Escherichia coli, GI1790686, Length=597, Percent_Identity=25.1256281407035, Blast_Score=140, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005144
- InterPro:   IPR003586
- InterPro:   IPR003587
- InterPro:   IPR007869
- InterPro:   IPR006142
- InterPro:   IPR004042
- InterPro:   IPR006141
- InterPro:   IPR012833 [H]

Pfam domain/function: PF03477 ATP-cone; PF05204 Hom_end [H]

EC number: 1.17.4.2

Molecular weight: Translated: 87510; Mature: 87378

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASGSKYADLEISVVKRSGNEESFNVNKFVKSLITSGVDYENVDTILSEIQGKFYNGMST
CCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCH
EDLKSVVYSILKEYDKKTGKSYSKKYMSENCLKIRTSEKEFESFNKEKIVKALIQEAGAD
HHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCEEEECCHHHHHHCCHHHHHHHHHHHCCCC
LKTAERIALEVESEVKTLNLSYLTAPMIREIVNTKLIEHGLEEFRHKHTRLGIPVYDIIK
HHHHHHHHHEEHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
LIEKGSKDNANLMHNPESIHKWVADETMKQFALLNVFPKYIADAHMRGDIHLHDLEYAAV
HHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHH
RTVCCQHDLRQFFMHGLKVDGTGRHTSVSKPAKHPDVALQHAAKVLSAAQCEMSGGQSID
HHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCH
EFNVWIAPYIKGLPYDEVKQLMQLFIYEMNQIYAARGGQVVFSSINLELEVPEYLKGKPA
HHHEEHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECEEEECCHHHCCCCC
VKAGQIVGAYEEYDYEVKLIAKALVDVLMQGDAYGKPFLFPNIIFKLRENAFKDENKDLM
CCCCCEEECHHHCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEE
IKIHELSAKWGLPYFINMFADYQFKNTNAMGCRTRLSGDWGNSVEESSLRTGNMQWYTVN
EEEEECCCCCCCHHHHHHHHCCEECCCCCCCCEEECCCCCCCCCCHHHCCCCCEEEEEEE
LPRIAYEADGDDGKLFELLEEKLSLIKHGLELKHEITKKRLYHDKTHPFLTQKFDDEQYY
CCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCCC
GYDNTTKTFGFVGLNELLKYHVGSEIHDTKDSLDFGEKVISFIRNYADSLKKETGLRWTV
CCCCCCCEEEHHHHHHHHHHHCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
TQTPAESTAGRFAKLDYKYYREETKSVVNGELSDLNSIYYTNSSHVRVNAPVTLGEKVSI
ECCCCHHHCCHHHHHHHHHHHHHHHHHHCCCHHHCCEEEEECCCCEEEECCEECCCCCCH
EEKFHSLCNGGHIGHFWNAEAYANPEVLMEITQKMAKTNIGFFTYTKNLSICEKCSLAMG
HHHHHHHHCCCCCCCEECCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHC
GLKDNCNGCGSNSIERFSRITGYLQNVSNWNKAKQKELTDRKSNLIKF
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ASGSKYADLEISVVKRSGNEESFNVNKFVKSLITSGVDYENVDTILSEIQGKFYNGMST
CCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCH
EDLKSVVYSILKEYDKKTGKSYSKKYMSENCLKIRTSEKEFESFNKEKIVKALIQEAGAD
HHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCEEEECCHHHHHHCCHHHHHHHHHHHCCCC
LKTAERIALEVESEVKTLNLSYLTAPMIREIVNTKLIEHGLEEFRHKHTRLGIPVYDIIK
HHHHHHHHHEEHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
LIEKGSKDNANLMHNPESIHKWVADETMKQFALLNVFPKYIADAHMRGDIHLHDLEYAAV
HHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHH
RTVCCQHDLRQFFMHGLKVDGTGRHTSVSKPAKHPDVALQHAAKVLSAAQCEMSGGQSID
HHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCH
EFNVWIAPYIKGLPYDEVKQLMQLFIYEMNQIYAARGGQVVFSSINLELEVPEYLKGKPA
HHHEEHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECEEEECCHHHCCCCC
VKAGQIVGAYEEYDYEVKLIAKALVDVLMQGDAYGKPFLFPNIIFKLRENAFKDENKDLM
CCCCCEEECHHHCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEE
IKIHELSAKWGLPYFINMFADYQFKNTNAMGCRTRLSGDWGNSVEESSLRTGNMQWYTVN
EEEEECCCCCCCHHHHHHHHCCEECCCCCCCCEEECCCCCCCCCCHHHCCCCCEEEEEEE
LPRIAYEADGDDGKLFELLEEKLSLIKHGLELKHEITKKRLYHDKTHPFLTQKFDDEQYY
CCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCCC
GYDNTTKTFGFVGLNELLKYHVGSEIHDTKDSLDFGEKVISFIRNYADSLKKETGLRWTV
CCCCCCCEEEHHHHHHHHHHHCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
TQTPAESTAGRFAKLDYKYYREETKSVVNGELSDLNSIYYTNSSHVRVNAPVTLGEKVSI
ECCCCHHHCCHHHHHHHHHHHHHHHHHHCCCHHHCCEEEEECCCCEEEECCEECCCCCCH
EEKFHSLCNGGHIGHFWNAEAYANPEVLMEITQKMAKTNIGFFTYTKNLSICEKCSLAMG
HHHHHHHHCCCCCCCEECCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHC
GLKDNCNGCGSNSIERFSRITGYLQNVSNWNKAKQKELTDRKSNLIKF
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Ca2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2'-deoxyribonucleoside triphosphate; thioredoxin disulfide; H2O

Specific reaction: 2'-deoxyribonucleoside triphosphate + thioredoxin disulfide + H2O = ribonucleoside triphosphate + thioredoxin

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]