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The map label for this gene is queC

Identifier: 150399982

GI number: 150399982

Start: 1271609

End: 1272310

Strand: Reverse

Name: queC

Synonym: Mevan_1240

Alternate gene names: 150399982

Gene position: 1272310-1271609 (Counterclockwise)

Preceding gene: 150399983

Following gene: 150399981

Centisome position: 73.97

GC content: 32.34

Gene sequence:

>702_bases
ATGAAGGCTATCTCGGTATTAAGCGGGGGACTCGATTCTTTAGTGACTTCAATGGTTGCAAAAAAGGAAAATTCTGAAAT
AGCAACAGTTACATTTAATTACGGGCAGATGGCCCTTGATAAAGAACTAAAATCTGCTAAAAAAATTTCTAAAGTACTTG
GTGCAGAAAATCAGGTATTTGACATATCTTTTGTAAAAGAATTTAGTAAAAGTGGCCTAAATACTGGAAATATTCCTAAC
CCAAAAAAAGATGACCTAGATGATTTTAAAGAGTCTGAAAAAACTATGAAATCAGTTTGGGTTCCTGCAAGAAACATGAT
AATGTTTTCAATTGCTTCAGGCTTTGCAGAAGGGATAAATGCAGAAAAAATATATTCAGGATTAAATAAAGAAGAAGGAG
TAACCTTTCCAGACAATTCTACTGAATTTATAAATAGTTTTAATAAAAGCCTTGAATATGGGACACTAAATAAAGTTAAA
ATGTATGCTCCACTTTATAATCTCGATAAAGTTGAAATAGCAACTTTTGGAAAAAGATTAGAAGACGAATTAGGTTTGGA
CATTTTAAAATACAGTTACTCTTGTTACAGAGATAATTTAAAAGATTACCTACACTGCGGAACTTGTGAAAGCTGTATGC
GACGAAAAAGAGCGTTTGAATCTGCCGGAATCGTTGACCCAACAAACTATATTCTTCAATAA

Upstream 100 bases:

>100_bases
TTAAATTTTTTTAAAGTAATTTTTATATGACATATAATTTCTATAATTTTAAATACTCTTAAATATATAAAGTGAATGAT
TTAACATAAAAGGTGTTTTA

Downstream 100 bases:

>100_bases
GTGAAAAAATGATTGTAATCCCAAGATATTCTCTAATTAAAGAAAAAGCATCTGAAAGACTGCCTGAACTTCTTGAAAAT
CTTAATTTAAAAAAACCTCT

Product: exsB protein

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; Archaeosine biosynthesis protein queC; PreQ(0) synthase

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MKAISVLSGGLDSLVTSMVAKKENSEIATVTFNYGQMALDKELKSAKKISKVLGAENQVFDISFVKEFSKSGLNTGNIPN
PKKDDLDDFKESEKTMKSVWVPARNMIMFSIASGFAEGINAEKIYSGLNKEEGVTFPDNSTEFINSFNKSLEYGTLNKVK
MYAPLYNLDKVEIATFGKRLEDELGLDILKYSYSCYRDNLKDYLHCGTCESCMRRKRAFESAGIVDPTNYILQ

Sequences:

>Translated_233_residues
MKAISVLSGGLDSLVTSMVAKKENSEIATVTFNYGQMALDKELKSAKKISKVLGAENQVFDISFVKEFSKSGLNTGNIPN
PKKDDLDDFKESEKTMKSVWVPARNMIMFSIASGFAEGINAEKIYSGLNKEEGVTFPDNSTEFINSFNKSLEYGTLNKVK
MYAPLYNLDKVEIATFGKRLEDELGLDILKYSYSCYRDNLKDYLHCGTCESCMRRKRAFESAGIVDPTNYILQ
>Mature_233_residues
MKAISVLSGGLDSLVTSMVAKKENSEIATVTFNYGQMALDKELKSAKKISKVLGAENQVFDISFVKEFSKSGLNTGNIPN
PKKDDLDDFKESEKTMKSVWVPARNMIMFSIASGFAEGINAEKIYSGLNKEEGVTFPDNSTEFINSFNKSLEYGTLNKVK
MYAPLYNLDKVEIATFGKRLEDELGLDILKYSYSCYRDNLKDYLHCGTCESCMRRKRAFESAGIVDPTNYILQ

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family

Homologues:

Organism=Escherichia coli, GI1786648, Length=217, Percent_Identity=28.5714285714286, Blast_Score=99, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): QUEC_METVS (A6URL5)

Other databases:

- EMBL:   CP000742
- RefSeq:   YP_001323749.1
- STRING:   A6URL5
- GeneID:   5324938
- GenomeReviews:   CP000742_GR
- KEGG:   mvn:Mevan_1240
- eggNOG:   arNOG08306
- HOGENOM:   HBG553284
- OMA:   GWAEVLG
- ProtClustDB:   CLSK876541
- HAMAP:   MF_01633_A
- InterPro:   IPR018317
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PIRSF:   PIRSF006293
- TIGRFAMs:   TIGR00364

Pfam domain/function: PF06508 ExsB

EC number: NA

Molecular weight: Translated: 26086; Mature: 26086

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAISVLSGGLDSLVTSMVAKKENSEIATVTFNYGQMALDKELKSAKKISKVLGAENQVF
CCHHHHHHCCHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCEE
DISFVKEFSKSGLNTGNIPNPKKDDLDDFKESEKTMKSVWVPARNMIMFSIASGFAEGIN
HHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCC
AEKIYSGLNKEEGVTFPDNSTEFINSFNKSLEYGTLNKVKMYAPLYNLDKVEIATFGKRL
HHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHH
EDELGLDILKYSYSCYRDNLKDYLHCGTCESCMRRKRAFESAGIVDPTNYILQ
HHHHCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHCC
>Mature Secondary Structure
MKAISVLSGGLDSLVTSMVAKKENSEIATVTFNYGQMALDKELKSAKKISKVLGAENQVF
CCHHHHHHCCHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCEE
DISFVKEFSKSGLNTGNIPNPKKDDLDDFKESEKTMKSVWVPARNMIMFSIASGFAEGIN
HHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCC
AEKIYSGLNKEEGVTFPDNSTEFINSFNKSLEYGTLNKVKMYAPLYNLDKVEIATFGKRL
HHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHH
EDELGLDILKYSYSCYRDNLKDYLHCGTCESCMRRKRAFESAGIVDPTNYILQ
HHHHCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA