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The map label for this gene is 150399897

Identifier: 150399897

GI number: 150399897

Start: 1169724

End: 1170818

Strand: Reverse

Name: 150399897

Synonym: Mevan_1154

Alternate gene names: NA

Gene position: 1170818-1169724 (Counterclockwise)

Preceding gene: 150399901

Following gene: 150399896

Centisome position: 68.07

GC content: 29.04

Gene sequence:

>1095_bases
ATGACTTATGATGTTTTGAAATTTAAACCTACTGGTGATAAATTGAATTTAAAAAATGAGTATGCAGGGTTTTTATTAAG
TGGCGAACATGAACATCTCCCCTTTTCAGAATTAAATGCCCTTTTAGAAATATTTAATATTAAAGCTGAAAATTTAAAAA
TATTTAAAAATTATGCTGTATTTAATGGAATTATTTCAAAAGAAAATATTCAAAATATAGTAAAAAGAGGAGGATATATT
AACGAAGGGCATTTAATTCTTTTTGAGTGTCCCTTTGATGAATTTAACTTAGAAAAAAGTATCGAAGAACTTTATAGAAT
TTCCGAAATTACGGATTTTCCAATTTCTAAAAATGAAACTTTTGCAGTTAGAGTACATAAGTTAGACCGTGAAAAAGTTG
CTAAATCCATGGAAATAGAAAGAAAAATGGGTTCTATCATAAAAAGTAAAACCTTTTCGAGCGTTAATCTTAAAAACCCT
GAAAAAACCATAAAAATCGTAATTTCGGATAATTTAGCATATGTGTCAGTAGTTCTTGAAAAAAGGGATGTTGAATACTT
TCAAAATAACCGGCCACATTTAAGAGCTTACTTTCATCCAGGGTGCATAATGCCAAAGCTTGCACGCTGCATGGTAAATC
TTTCAAGGATTAACGAAAATGATATTTTACTTGATCCGTTTTGTGGAACTGGCGGTTTTTTAATAGAAGCCGGATTAATA
GGATGTAATGTAATTGGAAGTGATATAGATGAACAAATGGTAAACGGTGCCATTTTAAATCTAAATACTTACGACTTATC
TAAAAAAACAATATCAATCAAAAAATGGAATGCAAAAAATATATTAGACTACCTAAAAAGCCTCAATATCGAGAAAATAG
ATGCTGTTGTCACTGATCCGCCCTATGGAATATCAACTTCAAAAAAAGGGGATATTTTGGAAATATTTGAAGGAATAGTG
GAAATATTAAAAAAAGGAGATTATTTAGTGTTTGCTGCCCCAAATAAAATGAAATTAAATTTAGAATTAACCGAATTTTA
TGAAATGAGGGTTCATAAAAGCCTTACAAGATACATTCATGTTTACAAAAAATAA

Upstream 100 bases:

>100_bases
TTCAACTTTCCCATTTTTAATGCGGTGCATCGCTTTGGGTCGCACTGTTTTTCATGATATATGAAAAGTTTCATTGGAAA
TCACAAGATATATATGATAA

Downstream 100 bases:

>100_bases
TTAGAGAACCATTAAAAAATTAATAAAAAAATATTTATAAGTTTTTTAATCATATTTAAAGTCTTCAAGTTCTTTTTTAA
CTTCTTCTAAACTTGTATTA

Product: putative RNA methylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 364; Mature: 363

Protein sequence:

>364_residues
MTYDVLKFKPTGDKLNLKNEYAGFLLSGEHEHLPFSELNALLEIFNIKAENLKIFKNYAVFNGIISKENIQNIVKRGGYI
NEGHLILFECPFDEFNLEKSIEELYRISEITDFPISKNETFAVRVHKLDREKVAKSMEIERKMGSIIKSKTFSSVNLKNP
EKTIKIVISDNLAYVSVVLEKRDVEYFQNNRPHLRAYFHPGCIMPKLARCMVNLSRINENDILLDPFCGTGGFLIEAGLI
GCNVIGSDIDEQMVNGAILNLNTYDLSKKTISIKKWNAKNILDYLKSLNIEKIDAVVTDPPYGISTSKKGDILEIFEGIV
EILKKGDYLVFAAPNKMKLNLELTEFYEMRVHKSLTRYIHVYKK

Sequences:

>Translated_364_residues
MTYDVLKFKPTGDKLNLKNEYAGFLLSGEHEHLPFSELNALLEIFNIKAENLKIFKNYAVFNGIISKENIQNIVKRGGYI
NEGHLILFECPFDEFNLEKSIEELYRISEITDFPISKNETFAVRVHKLDREKVAKSMEIERKMGSIIKSKTFSSVNLKNP
EKTIKIVISDNLAYVSVVLEKRDVEYFQNNRPHLRAYFHPGCIMPKLARCMVNLSRINENDILLDPFCGTGGFLIEAGLI
GCNVIGSDIDEQMVNGAILNLNTYDLSKKTISIKKWNAKNILDYLKSLNIEKIDAVVTDPPYGISTSKKGDILEIFEGIV
EILKKGDYLVFAAPNKMKLNLELTEFYEMRVHKSLTRYIHVYKK
>Mature_363_residues
TYDVLKFKPTGDKLNLKNEYAGFLLSGEHEHLPFSELNALLEIFNIKAENLKIFKNYAVFNGIISKENIQNIVKRGGYIN
EGHLILFECPFDEFNLEKSIEELYRISEITDFPISKNETFAVRVHKLDREKVAKSMEIERKMGSIIKSKTFSSVNLKNPE
KTIKIVISDNLAYVSVVLEKRDVEYFQNNRPHLRAYFHPGCIMPKLARCMVNLSRINENDILLDPFCGTGGFLIEAGLIG
CNVIGSDIDEQMVNGAILNLNTYDLSKKTISIKKWNAKNILDYLKSLNIEKIDAVVTDPPYGISTSKKGDILEIFEGIVE
ILKKGDYLVFAAPNKMKLNLELTEFYEMRVHKSLTRYIHVYKK

Specific function: Unknown

COG id: COG1041

COG function: function code L; Predicted DNA modification methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 THUMP domain [H]

Homologues:

Organism=Homo sapiens, GI94420683, Length=345, Percent_Identity=26.6666666666667, Blast_Score=84, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6324448, Length=317, Percent_Identity=26.1829652996845, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005885
- InterPro:   IPR002052
- InterPro:   IPR002296
- InterPro:   IPR000241
- InterPro:   IPR004114 [H]

Pfam domain/function: PF02926 THUMP; PF01170 UPF0020 [H]

EC number: NA

Molecular weight: Translated: 41706; Mature: 41575

Theoretical pI: Translated: 8.18; Mature: 8.18

Prosite motif: PS51165 THUMP ; PS00092 N6_MTASE ; PS01261 UPF0020

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYDVLKFKPTGDKLNLKNEYAGFLLSGEHEHLPFSELNALLEIFNIKAENLKIFKNYAV
CCCEEEEEECCCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHCCCCCCEEEEEHHHH
FNGIISKENIQNIVKRGGYINEGHLILFECPFDEFNLEKSIEELYRISEITDFPISKNET
HHCCCCHHHHHHHHHCCCEECCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCE
FAVRVHKLDREKVAKSMEIERKMGSIIKSKTFSSVNLKNPEKTIKIVISDNLAYVSVVLE
EEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCEEEEEEEH
KRDVEYFQNNRPHLRAYFHPGCIMPKLARCMVNLSRINENDILLDPFCGTGGFLIEAGLI
HHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEECEE
GCNVIGSDIDEQMVNGAILNLNTYDLSKKTISIKKWNAKNILDYLKSLNIEKIDAVVTDP
ECEECCCCHHHHHHCCEEEEEEEEECCCEEEEEEECCHHHHHHHHHHCCHHHEEEEECCC
PYGISTSKKGDILEIFEGIVEILKKGDYLVFAAPNKMKLNLELTEFYEMRVHKSLTRYIH
CCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHH
VYKK
EECC
>Mature Secondary Structure 
TYDVLKFKPTGDKLNLKNEYAGFLLSGEHEHLPFSELNALLEIFNIKAENLKIFKNYAV
CCEEEEEECCCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHCCCCCCEEEEEHHHH
FNGIISKENIQNIVKRGGYINEGHLILFECPFDEFNLEKSIEELYRISEITDFPISKNET
HHCCCCHHHHHHHHHCCCEECCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCE
FAVRVHKLDREKVAKSMEIERKMGSIIKSKTFSSVNLKNPEKTIKIVISDNLAYVSVVLE
EEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCEEEEEEEH
KRDVEYFQNNRPHLRAYFHPGCIMPKLARCMVNLSRINENDILLDPFCGTGGFLIEAGLI
HHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEECEE
GCNVIGSDIDEQMVNGAILNLNTYDLSKKTISIKKWNAKNILDYLKSLNIEKIDAVVTDP
ECEECCCCHHHHHHCCEEEEEEEEECCCEEEEEEECCHHHHHHHHHHCCHHHEEEEECCC
PYGISTSKKGDILEIFEGIVEILKKGDYLVFAAPNKMKLNLELTEFYEMRVHKSLTRYIH
CCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHH
VYKK
EECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]