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The map label for this gene is bioW [H]

Identifier: 150399637

GI number: 150399637

Start: 908048

End: 908785

Strand: Reverse

Name: bioW [H]

Synonym: Mevan_0887

Alternate gene names: 150399637

Gene position: 908785-908048 (Counterclockwise)

Preceding gene: 150399639

Following gene: 150399636

Centisome position: 52.83

GC content: 29.95

Gene sequence:

>738_bases
ATGTTTAGTTTGAAAATGCGAGCTTCAAAAGATGGAGTCCATGTTTCGGGTGCAGAACGAATATCTACCGAAAATAAAAT
TGAAGAAATAGCAAATAGCCTAATAAAAAGAGCATTATTTCATGAAAACGGAACTCCGGATACTATAAACTTAAAACTGG
AAAAAATTACTAGTGAAATAACTTATTTAAAACATATTCCCATAAAAACGCTTATTTCAAATAACAAAGAAACTTCAAGG
AATATTTCAAGGAATATTTTAAGAAAAGAACTTGAAGTGTACTTTTTAAAAAATGGTAAAGATTTTGGAAAAATTGATAT
TTTGATTGATACTGCTTTTGAAATTATTGATAAAGGAAATATGAGGGGGGCTGCAGTTTTGGATTTAGATGGAAATAGGC
TCGAAGAAGATACTGAAAAAGGAGTTCGTGTAAAAAATATTGATACATCTGAGGAATTAAAAAGTAAAATATTAGCTGAT
TCAAAATTAACTGATAGAACAATTGATGCGATAGCAATTGCAACAAAGGTTTTGAATTTCGGGTTTATTGCAGAAATTTG
CACGTCAGATAACTATTCTTACAATATAGGATACGTGGCAACGAAATCGGGGTATTTCAGGATACCAAATCTCAAAAATG
AGGGCGAATTTGGTGGAAGGGTGTTTTTTATAGAAAATTCAGCAAATATTGAAGAAATTTTTGAAAAAATCGAAAAAACT
CCAGTAATTGTTTATTAG

Upstream 100 bases:

>100_bases
AATGAAAAATAATGATAGATTCTCCGTATTTATTGTAATTATCAATAATGATAAATAATAAAAAATACAACATTTAAAAA
ACGAGAAATATGTGATTAAA

Downstream 100 bases:

>100_bases
GTGTTTTCATGTTTAGGGAAAAGTTAAAAAGAGAACTTCAGGGAATAAAAGATGAAAATTTATATAGGAAATTAAGAAAT
CAAGATGATTTTATTTTAAA

Product: 6-carboxyhexanoate--CoA ligase

Products: NA

Alternate protein names: Pimeloyl-CoA synthase [H]

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MFSLKMRASKDGVHVSGAERISTENKIEEIANSLIKRALFHENGTPDTINLKLEKITSEITYLKHIPIKTLISNNKETSR
NISRNILRKELEVYFLKNGKDFGKIDILIDTAFEIIDKGNMRGAAVLDLDGNRLEEDTEKGVRVKNIDTSEELKSKILAD
SKLTDRTIDAIAIATKVLNFGFIAEICTSDNYSYNIGYVATKSGYFRIPNLKNEGEFGGRVFFIENSANIEEIFEKIEKT
PVIVY

Sequences:

>Translated_245_residues
MFSLKMRASKDGVHVSGAERISTENKIEEIANSLIKRALFHENGTPDTINLKLEKITSEITYLKHIPIKTLISNNKETSR
NISRNILRKELEVYFLKNGKDFGKIDILIDTAFEIIDKGNMRGAAVLDLDGNRLEEDTEKGVRVKNIDTSEELKSKILAD
SKLTDRTIDAIAIATKVLNFGFIAEICTSDNYSYNIGYVATKSGYFRIPNLKNEGEFGGRVFFIENSANIEEIFEKIEKT
PVIVY
>Mature_245_residues
MFSLKMRASKDGVHVSGAERISTENKIEEIANSLIKRALFHENGTPDTINLKLEKITSEITYLKHIPIKTLISNNKETSR
NISRNILRKELEVYFLKNGKDFGKIDILIDTAFEIIDKGNMRGAAVLDLDGNRLEEDTEKGVRVKNIDTSEELKSKILAD
SKLTDRTIDAIAIATKVLNFGFIAEICTSDNYSYNIGYVATKSGYFRIPNLKNEGEFGGRVFFIENSANIEEIFEKIEKT
PVIVY

Specific function: Transforms pimelate into pimeloyl-CoA [H]

COG id: COG1424

COG function: function code H; Pimeloyl-CoA synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BioW family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005499
- ProDom:   PD017229 [H]

Pfam domain/function: PF03744 BioW [H]

EC number: =6.2.1.14 [H]

Molecular weight: Translated: 27662; Mature: 27662

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSLKMRASKDGVHVSGAERISTENKIEEIANSLIKRALFHENGTPDTINLKLEKITSEI
CCEEEECCCCCCEEECCHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHH
TYLKHIPIKTLISNNKETSRNISRNILRKELEVYFLKNGKDFGKIDILIDTAFEIIDKGN
HHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHEEEEEECCCCCCEEEEEEEHHHHHHCCCC
MRGAAVLDLDGNRLEEDTEKGVRVKNIDTSEELKSKILADSKLTDRTIDAIAIATKVLNF
CCCEEEEECCCCCCCCHHHCCCEEECCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
GFIAEICTSDNYSYNIGYVATKSGYFRIPNLKNEGEFGGRVFFIENSANIEEIFEKIEKT
HHHHHHHCCCCCEEEEEEEEECCCEEECCCCCCCCCCCCEEEEEECCCCHHHHHHHHHCC
PVIVY
CEEEC
>Mature Secondary Structure
MFSLKMRASKDGVHVSGAERISTENKIEEIANSLIKRALFHENGTPDTINLKLEKITSEI
CCEEEECCCCCCEEECCHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHH
TYLKHIPIKTLISNNKETSRNISRNILRKELEVYFLKNGKDFGKIDILIDTAFEIIDKGN
HHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHEEEEEECCCCCCEEEEEEEHHHHHHCCCC
MRGAAVLDLDGNRLEEDTEKGVRVKNIDTSEELKSKILADSKLTDRTIDAIAIATKVLNF
CCCEEEEECCCCCCCCHHHCCCEEECCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
GFIAEICTSDNYSYNIGYVATKSGYFRIPNLKNEGEFGGRVFFIENSANIEEIFEKIEKT
HHHHHHHCCCCCEEEEEEEEECCCEEECCCCCCCCCCCCEEEEEECCCCHHHHHHHHHCC
PVIVY
CEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]