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The map label for this gene is pgk [H]

Identifier: 150399596

GI number: 150399596

Start: 873991

End: 875235

Strand: Reverse

Name: pgk [H]

Synonym: Mevan_0845

Alternate gene names: 150399596

Gene position: 875235-873991 (Counterclockwise)

Preceding gene: 150399599

Following gene: 150399595

Centisome position: 50.88

GC content: 35.98

Gene sequence:

>1245_bases
ATGTTTTTGACCCTTGATGACTTTAATTTGGAAGGAAAAACGGTTGCATTACGTGTAGATATTAATAGTCCGATTGATGT
GAATAATGGGGCTATTTTGGATGACACGAGAATTAAAGCATGTTACAATACGATAAAAGACCTTTCTAACAAAGGTGCAA
AAGTAGTAATTTTGGCCCACCAGAGTAGGCCTGGAAAAAAGGATTTTACAACCCTCGAATCTCACGCAAAAAAATTATCC
GAGGTCTTAGGTATCGAAGTAGGATATGTTGATGGGTTATTGGGGTCTACTGTACGAGAATCTATTTTAGGGATGGACAA
CGGCGAAGTAATACTTCTTGAAAATGTAAGGCTTTTATCTGAAGAAGTCCTTTCAGAATGGAAATCTTGGGATAAAATTA
CCCCTGAAAAACAGGCAAAAACAATAATGGTAAAAAAATTACATCCTTTTTTTGATTATTTCGTAAATGATGCGTTTGCA
GCAGCCCACAGGGCCCAACCTTCACTTGTAGGCTTTTCATATTATATGCCAATGCTTTGTGGACGGGTCATGGAAAAAGA
ACTTTTTACGCTTACAAAAGTTATTAAAAATCCAGATAGGCCATGTGTATTTGCACTAGGGGGTGCAAAAGCGGATGACA
GTATCGAAGTAATTAAAAACGTGCTTGAAAAACAGACTGCTGATCAAGTAATTACAAGTGGGATTGTTGCAAATATATTT
TTAATTGCAAAAGGATTTAAATTGGGCCCTAACGAAAAATTAATTGACGATATGGGTTACACTGGGCAAGTAACTATTGC
AAAAGAGTTAATTGAAAAATACGGTGAGAAAATCGTAATACCTATTGATGCAGCTTTAAATATTGAAGGGGAAAGAAAAG
AAACTGAATTAAATTTAAATAATGAAGTAAGTCATCCAATCCATGATCTGGGTCAAAAAACAATTGAAAGTTATTGGGAA
ATTTTAAAGAATGCCAAGACAATAGTTGCAAACGGCCCTGCAGGAGTATTTGAAAACAAAAATTTCTTAAAAGGAACAGA
AGAAATTTTAAAAGCAACTGCAAGTTCAAAAGGATTTTCAGTAATTGGAGGCGGACATCTGTCTGCTGCTGCTGAAGTAG
TCGGAATTTCTGGAAATGTGGGCCACATAAGCACTGGAGGGGGTGCGTGTATTGAATTTTTGGCAGGAAAAAGACTTCCC
GTAATTGAAATGCTTTTAGAGTCTTATGAAAAACATAAAGCCTAA

Upstream 100 bases:

>100_bases
AGGATTGGAAAGATATATATAACTAAGTTATCTAGCTTTTAACGATTTAATGTCATAATAGTGCGAAAATAAAAGTAAAA
TATCAACTGGAGGATGCGTT

Downstream 100 bases:

>100_bases
TTCCATCAAAATATTTCATTTAGACTTATTTTTTACTCTTATTTTAAAAAAGTACTGAAAATATATTTTAAATGGAAAAT
TATATATAAGAATCAACTTA

Product: phosphoglycerate kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 414; Mature: 414

Protein sequence:

>414_residues
MFLTLDDFNLEGKTVALRVDINSPIDVNNGAILDDTRIKACYNTIKDLSNKGAKVVILAHQSRPGKKDFTTLESHAKKLS
EVLGIEVGYVDGLLGSTVRESILGMDNGEVILLENVRLLSEEVLSEWKSWDKITPEKQAKTIMVKKLHPFFDYFVNDAFA
AAHRAQPSLVGFSYYMPMLCGRVMEKELFTLTKVIKNPDRPCVFALGGAKADDSIEVIKNVLEKQTADQVITSGIVANIF
LIAKGFKLGPNEKLIDDMGYTGQVTIAKELIEKYGEKIVIPIDAALNIEGERKETELNLNNEVSHPIHDLGQKTIESYWE
ILKNAKTIVANGPAGVFENKNFLKGTEEILKATASSKGFSVIGGGHLSAAAEVVGISGNVGHISTGGGACIEFLAGKRLP
VIEMLLESYEKHKA

Sequences:

>Translated_414_residues
MFLTLDDFNLEGKTVALRVDINSPIDVNNGAILDDTRIKACYNTIKDLSNKGAKVVILAHQSRPGKKDFTTLESHAKKLS
EVLGIEVGYVDGLLGSTVRESILGMDNGEVILLENVRLLSEEVLSEWKSWDKITPEKQAKTIMVKKLHPFFDYFVNDAFA
AAHRAQPSLVGFSYYMPMLCGRVMEKELFTLTKVIKNPDRPCVFALGGAKADDSIEVIKNVLEKQTADQVITSGIVANIF
LIAKGFKLGPNEKLIDDMGYTGQVTIAKELIEKYGEKIVIPIDAALNIEGERKETELNLNNEVSHPIHDLGQKTIESYWE
ILKNAKTIVANGPAGVFENKNFLKGTEEILKATASSKGFSVIGGGHLSAAAEVVGISGNVGHISTGGGACIEFLAGKRLP
VIEMLLESYEKHKA
>Mature_414_residues
MFLTLDDFNLEGKTVALRVDINSPIDVNNGAILDDTRIKACYNTIKDLSNKGAKVVILAHQSRPGKKDFTTLESHAKKLS
EVLGIEVGYVDGLLGSTVRESILGMDNGEVILLENVRLLSEEVLSEWKSWDKITPEKQAKTIMVKKLHPFFDYFVNDAFA
AAHRAQPSLVGFSYYMPMLCGRVMEKELFTLTKVIKNPDRPCVFALGGAKADDSIEVIKNVLEKQTADQVITSGIVANIF
LIAKGFKLGPNEKLIDDMGYTGQVTIAKELIEKYGEKIVIPIDAALNIEGERKETELNLNNEVSHPIHDLGQKTIESYWE
ILKNAKTIVANGPAGVFENKNFLKGTEEILKATASSKGFSVIGGGHLSAAAEVVGISGNVGHISTGGGACIEFLAGKRLP
VIEMLLESYEKHKA

Specific function: Second phase of glycolysis; second step. [C]

COG id: COG0126

COG function: function code G; 3-phosphoglycerate kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate kinase family [H]

Homologues:

Organism=Homo sapiens, GI4505763, Length=421, Percent_Identity=35.3919239904988, Blast_Score=189, Evalue=3e-48,
Organism=Homo sapiens, GI31543397, Length=425, Percent_Identity=35.7647058823529, Blast_Score=186, Evalue=4e-47,
Organism=Escherichia coli, GI1789294, Length=425, Percent_Identity=34.8235294117647, Blast_Score=204, Evalue=6e-54,
Organism=Caenorhabditis elegans, GI17508823, Length=422, Percent_Identity=36.9668246445498, Blast_Score=207, Evalue=1e-53,
Organism=Saccharomyces cerevisiae, GI6319857, Length=420, Percent_Identity=33.0952380952381, Blast_Score=182, Evalue=9e-47,
Organism=Drosophila melanogaster, GI24581203, Length=421, Percent_Identity=33.9667458432304, Blast_Score=183, Evalue=2e-46,
Organism=Drosophila melanogaster, GI17136394, Length=423, Percent_Identity=34.9881796690307, Blast_Score=176, Evalue=2e-44,

Paralogues:

None

Copy number: 2990 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1460 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001576
- InterPro:   IPR015901
- InterPro:   IPR015824 [H]

Pfam domain/function: PF00162 PGK [H]

EC number: =2.7.2.3 [H]

Molecular weight: Translated: 45233; Mature: 45233

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLTLDDFNLEGKTVALRVDINSPIDVNNGAILDDTRIKACYNTIKDLSNKGAKVVILAH
CEEEEECCCCCCCEEEEEEECCCCEECCCCEEECCHHHHHHHHHHHHHHCCCCEEEEEEE
QSRPGKKDFTTLESHAKKLSEVLGIEVGYVDGLLGSTVRESILGMDNGEVILLENVRLLS
CCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHH
EEVLSEWKSWDKITPEKQAKTIMVKKLHPFFDYFVNDAFAAAHRAQPSLVGFSYYMPMLC
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
GRVMEKELFTLTKVIKNPDRPCVFALGGAKADDSIEVIKNVLEKQTADQVITSGIVANIF
HHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIAKGFKLGPNEKLIDDMGYTGQVTIAKELIEKYGEKIVIPIDAALNIEGERKETELNLN
HHHCCCCCCCCCHHHHHCCCCCEEHHHHHHHHHCCCEEEEEECCEEECCCCCCCCCCCCC
NEVSHPIHDLGQKTIESYWEILKNAKTIVANGPAGVFENKNFLKGTEEILKATASSKGFS
CCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCE
VIGGGHLSAAAEVVGISGNVGHISTGGGACIEFLAGKRLPVIEMLLESYEKHKA
EEECCCHHHHHHEEEECCCCCEEECCHHHHHHHHCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFLTLDDFNLEGKTVALRVDINSPIDVNNGAILDDTRIKACYNTIKDLSNKGAKVVILAH
CEEEEECCCCCCCEEEEEEECCCCEECCCCEEECCHHHHHHHHHHHHHHCCCCEEEEEEE
QSRPGKKDFTTLESHAKKLSEVLGIEVGYVDGLLGSTVRESILGMDNGEVILLENVRLLS
CCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHH
EEVLSEWKSWDKITPEKQAKTIMVKKLHPFFDYFVNDAFAAAHRAQPSLVGFSYYMPMLC
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
GRVMEKELFTLTKVIKNPDRPCVFALGGAKADDSIEVIKNVLEKQTADQVITSGIVANIF
HHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIAKGFKLGPNEKLIDDMGYTGQVTIAKELIEKYGEKIVIPIDAALNIEGERKETELNLN
HHHCCCCCCCCCHHHHHCCCCCEEHHHHHHHHHCCCEEEEEECCEEECCCCCCCCCCCCC
NEVSHPIHDLGQKTIESYWEILKNAKTIVANGPAGVFENKNFLKGTEEILKATASSKGFS
CCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCE
VIGGGHLSAAAEVVGISGNVGHISTGGGACIEFLAGKRLPVIEMLLESYEKHKA
EEECCCHHHHHHEEEECCCCCEEECCHHHHHHHHCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA