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The map label for this gene is pheA [H]

Identifier: 150399592

GI number: 150399592

Start: 871022

End: 871828

Strand: Reverse

Name: pheA [H]

Synonym: Mevan_0841

Alternate gene names: 150399592

Gene position: 871828-871022 (Counterclockwise)

Preceding gene: 150399593

Following gene: 150399591

Centisome position: 50.69

GC content: 31.85

Gene sequence:

>807_bases
ATGATATGCTGTCTTGGGCCAAAAGGGAGTTATAGTGAAAAAGCAGCCCAAAAATTTTCAGGATTACTAAATCAGGAAAT
TATATTTAAAAAATCAATATATGACGTTTTTAAGTCTCTTGAAACTGATTTTGAGCTTTTAGGGGTTGTTCCATCTGAAA
ATTCAATCGAAGGGTCAGTAACGATTACCCAAGACCTTTTTTTAGAGTTTCCGGTAAAAATTATTGGTGAAGTGGATATA
GAAATAAATCACAGTTTAATTGGGTATAATATCGAAAAGATAAGGGAAATACTCTCACACCCCCAAGCACTCGCTCAGTG
CGGCCGTTATATATATAAACACGGCTGGAAGGTAAGGCCCGTTGAAAGCACTGCAAAAGCTGCAAAAATCGTTTTCGAAG
AAAAAAATGAAGAATTAGCTGCAATTGGTTCAATTGAAAATGCAAGGATTTATGGCATAAAAGTTTTGGAAGAAAACGTT
CAAGATTATCAAAATAATAAAACAAGATTTTTTTTGATATGCAATAAAAATATGAATTTTAAAACGAATTTAATGCCATC
AAAATCTACAATAATCGTAGAATTAAAGAAAAACAGGCCCGGTGCATTTTATGAGCTTTTAGAAGTGTTTAAATATCGAA
ATGTTAATTTAACCAGAATAGAATCTAGGCCATCAAAAAAGGAAATTGGAAATTATGTATTTTATATCGATTATGAACAA
GATGATGATAATTTAGGATTACTCACTGATTTACGAAAGAGGGCATCAAATGTAATTGAAATTGGCAGTTACTTTGTAAT
CCGGTAA

Upstream 100 bases:

>100_bases
TTTTAAAAAAGATAATTGATTTATTTTTTAAAAATGACGAAAAAATTTCGAAATATTTAAAGTTTAAAGGACAGTTTTTA
ATTTGTAAGATGGTGAAAAA

Downstream 100 bases:

>100_bases
TTTATGATTTAACGGGCAGGTATTTCTATAAATACATATTAAACTATATATTAAACTATATATTTGAATATATAGTAAAG
TATTTATAGAAAGACTACTT

Product: prephenate dehydratase

Products: NA

Alternate protein names: PDT; MjPDT [H]

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MICCLGPKGSYSEKAAQKFSGLLNQEIIFKKSIYDVFKSLETDFELLGVVPSENSIEGSVTITQDLFLEFPVKIIGEVDI
EINHSLIGYNIEKIREILSHPQALAQCGRYIYKHGWKVRPVESTAKAAKIVFEEKNEELAAIGSIENARIYGIKVLEENV
QDYQNNKTRFFLICNKNMNFKTNLMPSKSTIIVELKKNRPGAFYELLEVFKYRNVNLTRIESRPSKKEIGNYVFYIDYEQ
DDDNLGLLTDLRKRASNVIEIGSYFVIR

Sequences:

>Translated_268_residues
MICCLGPKGSYSEKAAQKFSGLLNQEIIFKKSIYDVFKSLETDFELLGVVPSENSIEGSVTITQDLFLEFPVKIIGEVDI
EINHSLIGYNIEKIREILSHPQALAQCGRYIYKHGWKVRPVESTAKAAKIVFEEKNEELAAIGSIENARIYGIKVLEENV
QDYQNNKTRFFLICNKNMNFKTNLMPSKSTIIVELKKNRPGAFYELLEVFKYRNVNLTRIESRPSKKEIGNYVFYIDYEQ
DDDNLGLLTDLRKRASNVIEIGSYFVIR
>Mature_268_residues
MICCLGPKGSYSEKAAQKFSGLLNQEIIFKKSIYDVFKSLETDFELLGVVPSENSIEGSVTITQDLFLEFPVKIIGEVDI
EINHSLIGYNIEKIREILSHPQALAQCGRYIYKHGWKVRPVESTAKAAKIVFEEKNEELAAIGSIENARIYGIKVLEENV
QDYQNNKTRFFLICNKNMNFKTNLMPSKSTIIVELKKNRPGAFYELLEVFKYRNVNLTRIESRPSKKEIGNYVFYIDYEQ
DDDNLGLLTDLRKRASNVIEIGSYFVIR

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=247, Percent_Identity=32.3886639676113, Blast_Score=134, Evalue=5e-33,
Organism=Saccharomyces cerevisiae, GI6324013, Length=287, Percent_Identity=26.8292682926829, Blast_Score=77, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01842 ACT; PF00800 PDT [H]

EC number: =4.2.1.51 [H]

Molecular weight: Translated: 30788; Mature: 30788

Theoretical pI: Translated: 7.38; Mature: 7.38

Prosite motif: PS00858 PREPHENATE_DEHYDR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MICCLGPKGSYSEKAAQKFSGLLNQEIIFKKSIYDVFKSLETDFELLGVVPSENSIEGSV
CEEEECCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCEE
TITQDLFLEFPVKIIGEVDIEINHSLIGYNIEKIREILSHPQALAQCGRYIYKHGWKVRP
EEHHHHHHHCCCEEEEEEEEEECCEEECCCHHHHHHHHHCHHHHHHHHHHHHHCCCEEEE
VESTAKAAKIVFEEKNEELAAIGSIENARIYGIKVLEENVQDYQNNKTRFFLICNKNMNF
CHHHHHHHHHEEECCCCCEEEECCCCCCEEEEEEEHHHHHHHHHCCCEEEEEEECCCCCE
KTNLMPSKSTIIVELKKNRPGAFYELLEVFKYRNVNLTRIESRPSKKEIGNYVFYIDYEQ
EEECCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCEEEECCCCCHHHHCCEEEEEEEEC
DDDNLGLLTDLRKRASNVIEIGSYFVIR
CCCCCCHHHHHHHHHCCEEEECCEEEEC
>Mature Secondary Structure
MICCLGPKGSYSEKAAQKFSGLLNQEIIFKKSIYDVFKSLETDFELLGVVPSENSIEGSV
CEEEECCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCEE
TITQDLFLEFPVKIIGEVDIEINHSLIGYNIEKIREILSHPQALAQCGRYIYKHGWKVRP
EEHHHHHHHCCCEEEEEEEEEECCEEECCCHHHHHHHHHCHHHHHHHHHHHHHCCCEEEE
VESTAKAAKIVFEEKNEELAAIGSIENARIYGIKVLEENVQDYQNNKTRFFLICNKNMNF
CHHHHHHHHHEEECCCCCEEEECCCCCCEEEEEEEHHHHHHHHHCCCEEEEEEECCCCCE
KTNLMPSKSTIIVELKKNRPGAFYELLEVFKYRNVNLTRIESRPSKKEIGNYVFYIDYEQ
EEECCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCEEEECCCCCHHHHCCEEEEEEEEC
DDDNLGLLTDLRKRASNVIEIGSYFVIR
CCCCCCHHHHHHHHHCCEEEECCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]