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The map label for this gene is tadA [H]

Identifier: 150398810

GI number: 150398810

Start: 49601

End: 50041

Strand: Reverse

Name: tadA [H]

Synonym: Mevan_0051

Alternate gene names: 150398810

Gene position: 50041-49601 (Counterclockwise)

Preceding gene: 150398815

Following gene: 150398809

Centisome position: 2.91

GC content: 30.16

Gene sequence:

>441_bases
ATGACAAAATTCATGGAAGAAGCTATAAAAGAAGCAAAATTAGGGGCTATTGAAGGTGGAATTCCAATTGGGGCAGTTTT
AGTCTATAAAAATAAAGTTATCGGAAGAGGGCATAACAAAAGAATTCAAAAAAATAGTGTAGTATTTCATGCAGAAATGG
ATGCACTTGAAAATGCAGGACGCATTAATTCTAGTATTTATAAAGACTGCGAGCTTTATACTACTCTTTCACCGTGCATT
ATGTGTAGCGGTGCAATTTTATTATATAATATAAAAAAAGTGATTATTGGGGAAAATAAGACGTTTAAAGGTGCAGAAGA
ACTTTTAGAAAAAAATGGTGTTAAACTGGAAGTTTTAAATGATAAAAACTGCATAGATATGATGGAAGAATTTATAAAAA
GTAATGAAGAACTATGGAATGAAGATATTGGTAAAGAATAA

Upstream 100 bases:

>100_bases
TTAGAATTTATAAGTTGACAGTATAATACCCCTTTAAAATTAAGAACATATAAATACGTTTTTTAAAAGAAATAATTTAG
GCTTAAAAAATGGTGGTATA

Downstream 100 bases:

>100_bases
AAAAATAAAAAATAAAAATAAGGAATCGTGGTTTTTTATGAAAATAATAATTCTTGAGGGATATGCATAACTTCTAGGAA
TTATCTTGGAATAAATTGGA

Product: CMP/dCMP deaminase zinc-binding

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 146; Mature: 145

Protein sequence:

>146_residues
MTKFMEEAIKEAKLGAIEGGIPIGAVLVYKNKVIGRGHNKRIQKNSVVFHAEMDALENAGRINSSIYKDCELYTTLSPCI
MCSGAILLYNIKKVIIGENKTFKGAEELLEKNGVKLEVLNDKNCIDMMEEFIKSNEELWNEDIGKE

Sequences:

>Translated_146_residues
MTKFMEEAIKEAKLGAIEGGIPIGAVLVYKNKVIGRGHNKRIQKNSVVFHAEMDALENAGRINSSIYKDCELYTTLSPCI
MCSGAILLYNIKKVIIGENKTFKGAEELLEKNGVKLEVLNDKNCIDMMEEFIKSNEELWNEDIGKE
>Mature_145_residues
TKFMEEAIKEAKLGAIEGGIPIGAVLVYKNKVIGRGHNKRIQKNSVVFHAEMDALENAGRINSSIYKDCELYTTLSPCIM
CSGAILLYNIKKVIIGENKTFKGAEELLEKNGVKLEVLNDKNCIDMMEEFIKSNEELWNEDIGKE

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=115, Percent_Identity=35.6521739130435, Blast_Score=76, Evalue=1e-14,
Organism=Escherichia coli, GI145693172, Length=146, Percent_Identity=32.8767123287671, Blast_Score=80, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17554608, Length=96, Percent_Identity=40.625, Blast_Score=69, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17541138, Length=108, Percent_Identity=35.1851851851852, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6325319, Length=146, Percent_Identity=46.5753424657534, Blast_Score=140, Evalue=1e-34,
Organism=Drosophila melanogaster, GI21355527, Length=112, Percent_Identity=34.8214285714286, Blast_Score=66, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 16371; Mature: 16240

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKFMEEAIKEAKLGAIEGGIPIGAVLVYKNKVIGRGHNKRIQKNSVVFHAEMDALENAG
CCHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCEEEEEHHHHHHCCC
RINSSIYKDCELYTTLSPCIMCSGAILLYNIKKVIIGENKTFKGAEELLEKNGVKLEVLN
CCCHHHHHHHHHHHHHHHHHHHCCHHEEEEHHHHEECCCCCCCCHHHHHHCCCCEEEEEC
DKNCIDMMEEFIKSNEELWNEDIGKE
CCCHHHHHHHHHHCCHHHHHHCCCCC
>Mature Secondary Structure 
TKFMEEAIKEAKLGAIEGGIPIGAVLVYKNKVIGRGHNKRIQKNSVVFHAEMDALENAG
CHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCEEEEEHHHHHHCCC
RINSSIYKDCELYTTLSPCIMCSGAILLYNIKKVIIGENKTFKGAEELLEKNGVKLEVLN
CCCHHHHHHHHHHHHHHHHHHHCCHHEEEEHHHHEECCCCCCCCHHHHHHCCCCEEEEEC
DKNCIDMMEEFIKSNEELWNEDIGKE
CCCHHHHHHHHHHCCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]